DNA fragmentation in V79 cells irradiated with light ions as measured by pulsed-field gel electrophoresis. I. Experimental results

International Journal of Radiation Biology

Volumn 78, Issue 6, 2002, Pages 475-482

  Belli, M ^a,b   Cherubini, R ^c   Vecchia, M Dalla ^c   Dini, V ^a,b   Esposito, G ^a   Moschini, G ^c   Sapora, O ^a,b   Simone, G ^a,b   Tabocchini, M A ^a,b  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b INFN SEZIONE DI ROMA   (Italy)

^c LABORATORI NAZIONALI DI LEGNARO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DNA FRAGMENT; HELIUM; PROTON;

ANIMAL CELL; ARTICLE; CALIBRATION; CHO CELL; CONTROLLED STUDY; DNA STRAND BREAKAGE; GAMMA RADIATION; LOW ENERGY RADIATION; NONHUMAN; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; RADIATION DOSE; RADIOSENSITIVITY;

ANIMALS; CELL LINE; CRICETINAE; DNA; DNA DAMAGE; DNA FRAGMENTATION; ELECTROPHORESIS, GEL, PULSED-FIELD; GAMMA RAYS; HELIUM; PROTONS;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0036082849     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/09553000210123676     Document Type: Article

References (28)

1. RBE-LET relationships for cell inactivation and mutation induced by low energy protons in V79 cells: Further results at the LNL facility
2. DNA double-strand breaks induced by low energy protons in V79 cells
3. DNA fragmentation in mammalian cells exposed to various light ions
4. DSB induction and rejoining in V79 cells irradiated with light ions: A constant field gel electrophoresis study
5. Proton irradiation facility for radiobiological studies at a 7MeV Van de Graaff accelerator
6. In CHEF electrophoresis a linear induction of dsb corresponds to a nonlinear fraction of extracted DNA with dose
7. Enzymatic restriction of mammalian cell DNA: Evidence for double-strand breaks as potentially lethal lesions
8. Cell inactivation, mutation and DNA damage induced by light ions: Dependence on radiation quality
9. A quantitative model of DNA fragments generated by ionising radiation, and possible experimental applications
10. -1
11. Simulation of DNA fragment distributions after irradiation with photons
12. Initial events in the cellular effects of ionising radiations: Clustered damage to DNA
13. DNA damage induced by radiation of different linear energy transfer: Initial fragmentation
14. Induction and rejoining of DNA double-strand breaks in normal human skin fibroblasts after exposure to radiation of different linear energy transfer: Possible roles of track structure and chromatin organisation
15. Clusters of DNA damage induced by ionising radiation: Formation of short DNA fragments. I. Theoretical modelling
16. Non-random distribution of DNA double-strand breaks induced by particle irradiation
17. DNA double-strand break distributions in X-ray and α-particle irradiated V79 cells: Evidence for non-random breakage
18. The role of higher-order chromatin structure in the yield and distribution of DNA double-strand breaks in cells irradiated with X-rays and α-particles
19. DNA double-strand breaks induced by sparsely ionising radiation and endonucleases as critical lesions for cell death, chromosomal aberrations, mutation and oncogenic transformation
20. Use of radiation quality as a probe for DNA lesion complexity
21. A review of dsb induction data for varying quality radiations
22. Clusters of DNA damage induced by ionising radiation: Formation of short DNA fragments. II. Experimental detection
23. Radiation-induced heat-labile sites that convert into DNA double-strand breaks
24. Chromatin conformation in living cells: Support for a zig-zag model of the 30 nm chromatin fiber. Appendix: Theoretical modelling of DNA damage
25. The DNA content of some mammalian cells measured by flow cytometry and its influence on radiation sensitivity
26. Induction and rejoining of large DNA fragments after ion irradiation
27. DNA damage produced by ionising radiation in mammalian cells: Identities, mechanisms of formation and reparability