Simulation of DNA damage after proton irradiation

Radiation Research

Volumn 159, Issue 3, 2003, Pages 401-410

  Friedland, Werner ^a   Jacob, Peter ^a   Bernhardt, Philipp ^a   Paretzke, Herwig G ^a   Dingfelder, Michael ^a  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; PROTON; WATER;

ALGORITHM; ARTICLE; COMPUTER SIMULATION; DNA DAMAGE; DNA STRAND BREAKAGE; GENE TARGETING; GENOME; PRIORITY JOURNAL; PROTON RADIATION;

DNA; DNA DAMAGE; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, RADIATION; GENOME; HUMANS; MODELS, STATISTICAL; MONTE CARLO METHOD; PROTONS; SOFTWARE;

RICKETTSIA SP. PAR;

EID: 0037335592     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/0033-7587(2003)159[0401:SODDAP]2.0.CO;2     Document Type: Article

References (37)

1. C. von Sonntag, The Chemical Basis of Radiation Biology. Taylor & Francis, London and New York, 1987.
2. K. M. Prise, G. Ahnstrom, M. Belli, J. Carlsson, D. Frankenberg, J. Kiefer, M. Lobrich, B. D. Michael, J. Nygren and B. Stenerlow, A review of dsb induction data for varying quality radiations. Int. J. Radiat. Biol. 74, 173-184 (1998).
3. K. M. Prise, M. Pinto, H. C. Newman and B. D. Michael, A review of studies of ionizing radiation-induced double-strand break clustering. Radiat. Res. 156, 572-576 (2001).
4. M. Belli, F. Cera, R. Cherubini, F. Ianzini, G. Moschini, O. Sapora, G. Simone, M. A. Tabocchini and P. Tiveron, DNA double-strand breaks induced by low energy protons in V79 cells. Int. J. Radiat. Biol. 65, 529-536 (1994).
5. T. J. Jenner, M. Belli, D. T. Goodhead, F. Ianzini, G. Simone and M. A. Tabocchini, Direct comparison of biological effectiveness of protons and alpha-particles of the same LET III. Initial yield of DNA double-strand breaks in V79 cells. Int. J. Radiat. Biol. 61, 631-637 (1992).
6. K. M. Prise, M. Folkard, S. Davies and B. D. Michael, The irradiation of V79 mammalian cells by protons with energies below 2 MeV. Part II. Measurement of oxygen enhancement ratios and DNA damage. Int. J. Radiat. Biol. 58, 261-277 (1990).
7. 4He ions in primary human skin fibroblasts in the LET range of 8 to 124 keV/nucleon. Radiat. Res. 151, 540-549 (1999).
8. M. Belli, R. Cherubini, M. Dalla Vecchia, V. Dini, G. Moschini, C. Signoretti, G. Simone, M. A. Tabocchini and P. Tiveron, DNA DSB induction and rejoining in V79 cells irradiated with light ions: A constant field gel electrophoresis study. Int. J. Radiat. Biol. 76, 1095-1104 (2000).
9. M. Belli, R. Cherubini, M. Dalla Vecchia, V. Dini, G. Esposito, G. Moschini, O. Sapora, C. Signoretti, G. Simone and M. A. Tabocchini, DNA fragmentation in mammalian cells exposed to various light ions. Adv. Space Res. 27, 393-399 (2001).
10. B. Cedervall, R. Wong, N. Albright, J. Dynlacht, P. Lambin and W. C. Dewey, Methods for the quantification of DNA double-strand breaks determined from the distribution of DNA fragment sizes measured by pulsed-field gel electrophoresis. Radiat. Res. 143, 8-16 (1995); Erratum, Radiat. Res. 144, 122 (1995).
11. M. Pinto, K. M. Prise and B. D. Michael, Quantification of radiation induced DNA DSBs in human fibroblasts by PFGE: Testing the applicability of random breakage models. Int. J. Radiat. Biol. 78, 375-388 (2002).
12. M. Belli, R. Cherubini, M. Dalla Vecchia, V. Dini, G. Esposito, G. Moschini, O. Sapora, G. Simone and M. A. Tabocchini, DNA fragmentation in V79 cells irradiated with light ions as measured by pulsed-field gel electrophoresis. I. Experimental results. Int. J. Radiat. Biol. 78, 475-482 (2002).
13. M. Pinto, H. C. Newman, K. M. Prise and B. D. Michael, Quantification of DNA damage by PFGE: Development of an analytical approach to correct for the background distribution. Int. J. Radiat. Biol. 76, 741-748 (2000).
14. H. C. Newman, K. M. Prise and B. D. Michael, The role of higherorder chromatin structure in the yield and distribution of DNA double-strand breaks in cells irradiated with X-rays or alpha-particles. Int. J. Radiat. Biol. 76, 1085-1093 (2000).
15. W. Friedland, P. Bernhardt, P. Jacob, H. G. Paretzke and M. Dingfelder, Simulation of DNA damage after proton and low-LET irradiation. Radiat. Prot. Dosim. 99, 99-102 (2002).
16. W. Friedland, P. Jacob, H. G. Paretzke and T. Stork, Monte Carlo simulation of the production of short DNA fragments by low-linear energy transfer radiation using higher-order DNA models. Radiat. Res. 150, 170-182 (1998).
17. W. Friedland, P. Jacob, H. G. Paretzke, M. Merzagora and A. Ottolenghi, Simulation of DNA fragment distributions after irradiation with photons. Radiat. Environ. Biophys. 38, 39-47 (1999).
18. M. Dingfelder, M. Inokuti and H. G. Paretzke, Inelastic-collision cross sections of liquid water for interactions of energetic protons. Radiat. Phys. Chem. 59, 255-275 (2000).
19. M. Dingfelder, D. Hantke, M. Inokuti and H. G. Paretzke, Electron inelastic-scattering cross sections in liquid water. Radiat. Phys. Chem. 53, 1-18 (1998).
20. ICRU, Stopping Powers and Ranges for Protons and Alpha Particles. Report 49, International Commission on Radiation Units and Measurements, Bethesda, MD, 1993.
21. M. Dingfelder, Cross section calculations in condensed media - charged particles in liquid water. Radiat. Prot. Dosim. 99, 23-28 (2002).
22. C. M. de Lara, M. A. Hill, T. J. Jenner, D. Papworth and P. O'Neill, Dependence of the yield of DNA double-strand breaks in Chinese hamster V79-4 cells on the photon energy of ultrasoft X rays. Radiat. Res. 155, 440-448 (2001).
23. J. Nygren, M. Ljungman and G. Ahnstrom, Chromatin structure and radiation-induced DNA strand breaks in human cells: Soluble scavengers and DNA-bound proteins offer a better protection against single- than double-strand breaks. Int. J. Radiat. Biol. 68, 11-18 (1995).
24. B. D. Michael and P. O'Neill, A sting in the tail of electron tracks. Science 287, 1603-1604 (2000).
25. B. Boudaiffa, P. Cloutier, D. Hunting, M. A. Huels and L. Sanche, Resonant formation of DNA strand breaks by low-energy (3 to 20 eV) electrons. Science 287, 1658-1660 (2000).
26. K. M. Prise, M. Folkard, B. D. Michael, B. Vojnovic, B. Brocklehurst, A. Hopkirk and I. H. Munro, Critical energies for SSB and DSB induction in plasmid DNA by low-energy photons: Action spectra for strand-break induction in plasmid DNA irradiated in vacuum. Int. J. Radiat. Biol. 76, 881-890 (2000).
27. V. V. Moiseenko, R. N. Hamm, A. J. Waker and W. V. Prestwich, Calculation of radiation-induced DNA damage from photons and tritium beta-particles. Part I: Model formulation and basic results. Radiat. Environ. Biophys. 40, 23-31 (2001).
28. F. Ballarini, M. Biaggi, M. Merzagora, A. Ottolenghi, M. Dingfelder, W. Friedland, P. Jacob and H. G. Paretzke, Stochastic aspects and uncertainties in the prechemical and chemical stages of electron tracks in liquid water: A quantitative analysis based on Monte Carlo simulations. Radiat. Environ. Biophys. 39, 179-188 (2000).
29. G. V. Buxton, C. L. Greenstock, W. P. Helman and A. B. Ross, Critical review of rate constants for reactions of hydrated electrons, hydrogen atoms and hydroxyl radicals in aqueous solution. J. Phys. Chem. Ref. Data 17, 513-886 (1988).
30. R. N. Hamm, J. E. Turner and M. G. Stabin, Monte Carlo simulation of diffusion and reaction in water radiolysis - a study of reactant 'jump through' and jump distances. Radiat. Environ. Biophys. 36, 229-234 (1998).
31. J. R. Milligan, J. A. Aguilera and J. F. Ward, Variation of singlestrand break yield with scavenger concentration for plasmid DNA irradiated in aqueous solution. Radiat. Res. 133, 151-157 (1993).
32. V. V. Moiseenko, R. N. Hamm, A. J. Waker and W. V. Prestwich, The cellular environment in computer simulations of radiation-induced damage to DNA. Radiat. Environ. Biophys. 37, 167-172 (1998).
33. M. A. Siddiqi and E. Bothe, Single- and double-strand break formation in DNA irradiated in aqueous solution: Dependence on dose and OH radical scavenger concentration. Radiat. Res. 112, 449-463 (1987).
34. B. Cedervall and P. Kallman, Randomly distributed DNA doublestrand breaks as measured by pulsed field gel electrophoresis: A series of explanatory calculations. Radiat. Environ. Biophys. 33, 9-21 (1994).
35. C. R. Contopoulou, V. E. Cook and R. K. Mortimer, Analysis of DNA double strand breakage and repair using orthogonal field alternation gel electrophoresis. Yeast 3, 71-76 (1987).
36. H. Nikjoo, P. O'Neill, W. E. Wilson and D. T. Goodhead, Computational approach for determining the spectrum of DNA damage induced by ionizing radiation. Radiat. Res. 156, 577-583 (2001).
37. B. Rydberg, W. R. Holley, I. S. Mian and A. Chatterjee, Chromatin conformation in living cells: support for a zig-zag model of the 30 nm chromatin fiber. J. Mol. Biol. 284, 71-84 (1998).