Characterization and manipulation of the Pseudomonas aeruginosa dimethylarginine dimethylaminohydrolase monomer-dimer equilibrium

Journal of Molecular Biology

Volumn 341, Issue 1, 2004, Pages 171-184

  Plevin, Michael J ^a   Magalhães, Beatriz S ^a   Harris, Richard ^a   Sankar, Andrew ^b   Perkins, Stephen J ^a   Driscoll, Paul C ^a,b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b LUDWIG INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

ADMA, asymmetric dimethylarginine; AMA, asymmetric methylarginine; analytical ultracentrifugation; ASA, accessible surface area; AUC, analytical ultracentrifugation; dimethyl arginine; heteronuclear NMR; portain self association; site directed mutagenesis

Indexed keywords

ARGININE; BACTERIAL ENZYME; DIMER; DIMETHYLARGININASE; ENZYME VARIANT; GLUTAMIC ACID; HISTIDINE; MONOMER;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISSOCIATION CONSTANT; DRUG POTENCY; DRUG TARGETING; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME MECHANISM; ENZYME MODIFICATION; ENZYME STABILITY; ENZYME STRUCTURE; EQUILIBRIUM CONSTANT; GEL PERMEATION CHROMATOGRAPHY; LIGAND BINDING; MUTATION; NITROGEN NUCLEAR MAGNETIC RESONANCE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; PROTON NUCLEAR MAGNETIC RESONANCE; PSEUDOMONAS AERUGINOSA; SEDIMENTATION; SEDIMENTATION RATE; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS; ULTRACENTRIFUGATION; WILD TYPE;

BACTERIA (MICROORGANISMS); MAMMALIA; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

EID: 4143092645     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.05.057     Document Type: Article

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