Crystal structure and mechanism of human L-arginine:glycine amidinotransferase: A mitochondrial enzyme involved in creatine biosynthesis

EMBO Journal

Volumn 16, Issue 12, 1997, Pages 3373-3385

  Humm, Andreas ^a   Fritsche, Erich ^a   Steinbacher, Stefan ^a   Huber, Robert ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

Creatine; Induced fit; Pseudosymmetry; Reaction mechanism; Telluromethionine

Indexed keywords

AMIDINOTRANSFERASE; ARGININE; CREATINE; GLYCINE AMIDINOTRANSFERASE; GUANIDINOACETIC ACID; METHIONINE DERIVATIVE; MITOCHONDRIAL ENZYME; ORNITHINE;

AMINO ACID SYNTHESIS; ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; REACTION ANALYSIS; STEREOCHEMISTRY;

AMIDINOTRANSFERASES; AMINO ACID SEQUENCE; ANIMALS; ARGININE; BINDING SITES; COMPUTER GRAPHICS; CREATINE; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; HUMANS; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; ORNITHINE; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

EID: 0030978412     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.12.3373     Document Type: Article

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