Imbalances of chromosome 17 in medulloblastomas determined by comparative genomic hybridisation and fluorescence in situ hybridisation

Journal of Clinical Pathology - Molecular Pathology

Volumn 53, Issue 6, 2000, Pages 313-319

  Nicholson, J ^a   Wickramasinghe, C ^a   Ross, F ^b   Crolla, J ^b   Ellison, D ^a  

^a SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

^b SALISBURY DISTRICT HOSPITAL   (United Kingdom)

Author keywords

Comparative genomic hybridisation; Fluorescence in situ hybridisation; Medulloblastoma

Indexed keywords

PARAFFIN;

ADOLESCENT; ADULT; ARTICLE; CARCINOGENESIS; CENTROMERE; CHILD; CHROMOSOME 17; CHROMOSOME ABERRATION; CHROMOSOME LOSS; COMPARATIVE GENOMIC HYBRIDIZATION; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN TISSUE; INFANT; ISOCHROMOSOME; MAJOR CLINICAL STUDY; MEDULLOBLASTOMA; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; TELOMERE;

ADOLESCENT; ADULT; CEREBELLAR NEOPLASMS; CHILD; CHILD, PRESCHOOL; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 17; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INFANT; MEDULLOBLASTOMA; NUCLEIC ACID HYBRIDIZATION; PARAFFIN EMBEDDING; REPRODUCIBILITY OF RESULTS;

EID: 0033669529     PISSN: 13668714     EISSN: None     Source Type: Journal    
DOI: 10.1136/mp.53.6.313     Document Type: Article

References (35)

1. Epidemiology and prognosis in children treated for intracranial tumours in Denmark 1960-1984
2. Brain tumors in children
3. Cytogenetic analysis of 120 primary brain tumours and literature review
4. Isochromosome 17q in primitive neuroectodermal tumours of the central nervous system
5. Isochromosome 17q demonstrated by interphase fluorescence in situ hybridization in primitive neuroectodermal tumours of the central nervous system
6. Chromosomal characteristics of childhood brain tumors
7. Isochromosomes in neoplasia
8. Microsatellite analysis of childhood brain tumours
9. Deletion mapping of the medulloblastoma locus on chromosome 17p
10. Highresolution deletion mapping of chromosome arm 17p in childhood primitive neuroectodermal tumors reveals a common chromosomal disruption within the Smith-Magenis region, an unstable region in chromosome band 17p11.2
11. Detection of complete and partial chromosome gains and losses by comparative genomic in situ hybridization
12. Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors
13. Comparative genomic hybridization and histological variation in primitive neuroectodermal tumours
14. Extensive genomic abnormalities in childhood medulloblastoma by comparative genomic hybridization
15. Mapping of chromosomal gains and losses in primitive neuroectodermal tumours by comparative genomic hybridization
16. DNA in situ hybridization as an adjunct in tumor diagnosis
17. Fluorescence in situ hybridization in cancer and radiation biology
18. Comparison of fluorescence in situ hybridization analysis of isolated nuclei and routine histological sections from paraffin-embedded prostatic adenocarcinoma specimens
19. Physical deletion of the p53 gene in bladder cancer. Detection by fluorescence in situ hybridization
20. Optimising comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumours
21. A simple salting out procedure for extracting DNA from human nucleated cells
22. In situ hybridization as a tool to study numerical chromosome aberrations in solid bladder tumors
23. Analysis of chromosome 17p13 (p53 locus) alterations in gastric carcinoma cells by dual-color fluorescence in situ hybridization
24. Genetics of pediatric central nervous system tumors
25. Interphase cytogenetics reveals somatic pairing of chromosome 17 centromeres in normal human brain tissue, but no trisomy 7 or sex-chromosome loss
26. The utilization of interphase cytogenetic analysis for the detection of mosaicism
27. Detection of chromosome aneuploidy in interphase nuclei from human primary breast tumors using chromosome-specific repetitive DNA probes
28. Amplification of the c-erbB-2 (HER-2/neu) gene in gastric cancer cells. Detection by fluorescence in situ hybridization
29. Detection of an I(17q) chromosome by fluorescent in situ hybridization with a chromosome 17 alpha satellite DNA probe
30. Detection of chromosome aberrations in interphase tumor nuclei by nonradioactive in situ hybridization
31. Significance of trisomy 7 and 12 in thyroid lesions with follicular differentiation: A cytogenetic and in situ hybridization study
32. Prognostic implications of chromosome 17p deletions in human medulloblastomas
33. Prognostic significance of chromosome 17p deletions in childhood primitive neuroectodermal tumors (medulloblastomas) of the central nervous system
34. Correlation of chromosome 17p loss with clinical outcome in medulloblastoma
35. Molecular analysis of childhood primitive neuroectodermal tumors defines markers associated with poor outcome