An adhesin of the yeast pathogen Candida glabrata mediating adherence to human epithelial cells

Science

Volumn 285, Issue 5427, 1999, Pages 578-582

  Cormack, Brendan P ^a,b   Ghori, Nafisa ^a   Falkow, Stanley ^a,c  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DEPARTMENT OF PATHOLOGY   (United States)

^c PROTEIN DESIGN LABS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN;

ARTICLE; CANDIDA GLABRATA; CANDIDIASIS; CELL ADHESION; EPITHELIUM CELL; FUNGUS MUTATION; GENE DELETION; GENETIC SCREENING; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; VIRULENCE;

AMINO ACID SEQUENCE; ANIMALS; CALCIUM; CANDIDA; CANDIDIASIS, VULVOVAGINAL; CARBOHYDRATES; CELL ADHESION; CLONING, MOLECULAR; EPITHELIAL CELLS; FEMALE; FUNGAL PROTEINS; GENES, FUNGAL; HUMANS; LECTINS; LIGANDS; MICE; MICE, INBRED DBA; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; MUTATION; PLASMIDS; POLYMERASE CHAIN REACTION; TRANSFORMATION, GENETIC; TUMOR CELLS, CULTURED; VIRULENCE;

CANDIDA GLABRATA; FUNGI;

EID: 0033597797     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.285.5427.578     Document Type: Article

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47. We thank P. Fidel and J. Sobel for the gift of the C. glabrata clinical isolate; K. demons and D. Stevens for the clinical S. cerevisiae isolates; E. Ortega-Barria for many helpful discussions and advice; and J. Mecsas, C. Greider, and S. Fisher for a critical reading of the manuscript. This work was funded by a grant to S.F. from SmithKline Beecham. B.P.C. was supported by a postdoctoral fellowship from the Helen Hay Whitney Foundation and a career award from the Burroughs Wellcome Fund.