Anti-obesity and hypolipidemic effects of a proprietary herb and fiber combination (S&S PWH) in rats fed high-fat diets

Journal of Medicinal Food

Volumn 11, Issue 1, 2008, Pages 169-178

  Woo, Myoung Nam ^a   Bok, Song Hae ^b   Lee, Mi Kyung ^c   Kim, Hye Jin ^a   Jeon, Seon Min ^a   Do, Gyeong Min ^a   Shin, Su Kyung ^a   Ha, Tae Yeul ^d   Choi, Myung Sook ^a  

^a Kyungpook National University   (South Korea)

^b Bionutrigen   (South Korea)

^c Sunchon National University   (South Korea)

^d Korea Food Research Institute   (South Korea)

Author keywords

Anti obesity functional formula; Body weight; Lipid metabolism; Lipoprotein lipase; Phenolic compound; White adipose tissue

Indexed keywords

3 HYDROXY 3 METHYLGLUTARYL COENZYME A; ANTILIPEMIC AGENT; ANTIOBESITY AGENT; CHOLESTEROL; CHOLESTEROL ACYLTRANSFERASE; COENZYME A; CORN OIL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LARD; LIPOPROTEIN LIPASE; PHENOL DERIVATIVE; PLANT EXTRACT; TRIACYLGLYCEROL;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATHEROGENIC DIET; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG EFFICACY; DRUG MECHANISM; FIBER; HERB; LIPID DIET; LIPID METABOLISM; MALE; MEDICINAL PLANT; NONHUMAN; PRIORITY JOURNAL; RAT; SPRAGUE DAWLEY RAT; STATISTICAL SIGNIFICANCE; TRIACYLGLYCEROL BLOOD LEVEL;

ADIPOCYTES; ANIMALS; ANTI-OBESITY AGENTS; ANTILIPEMIC AGENTS; CHOLESTEROL; CHOLESTEROL, HDL; DIET; DIETARY FATS; DIETARY FIBER; EPIDIDYMIS; HEPATOCYTES; HYDROXYMETHYLGLUTARYL COA REDUCTASES; LIPOPROTEIN LIPASE; LIVER; MALE; PHENOLS; PHYTOTHERAPY; PLANT PREPARATIONS; RATS; RATS, SPRAGUE-DAWLEY; STEROL O-ACYLTRANSFERASE; TRIGLYCERIDES;

RATTUS; ZEA MAYS;

EID: 41349090882     PISSN: 1096620X     EISSN: None     Source Type: Journal    
DOI: 10.1089/jmf.2007.082     Document Type: Article

References (52)

1. Donahue RP, Abbott RD, Bloom E, Reed DM: Central obesity and coronary heart disease in men. Lancet 1987;11:821-824.
2. McNamara DJ: Dietary cholesterol and atherosclerosis. Biochim Biophys Acta 2000;1529:310-320.
3. Spiegelman BM, Flier JS: Obesity and regulation of energy balance. Cell 2001;104:531-543.
4. Knekt P, Jarvinen R, Seppanen R, Heliovaara M, Teppo L, Aroma A: Dietary flavonoids and the risk of lung cancer and other malignant neoplasms. Am J Epidemiol 1997;146:223-230.
5. Wilett WC: Balancing life-style and genomics research for disease prevention. Science 2002;296:695-698.
6. Kanekt P, Jarvinen R, Reunanen A, Maatela J: Flavonoid intake and coronary mortality in Finland: a cohort study. Br Med J 1996;312:478-481.
7. Le-Marchand L, Murphy SP, Hankin JH, Wilkens LR, Kolonel LN: Intake of flavonoids and lung cancer. J Natl Cancer Inst 2000;92:154-160.
8. Xing N, Chen Y, Mitchell SH, Young CYF: Quercetin inhibits the expression and function of the androgen receptor in LNCaP prostate cancer cells. Carcinogenesis 2001;22:409-414.
9. Yugarani T, Tan BK, The M, Das NP: Effects of polyphenolic natural products on the lipid profiles of rats fed high-fat diets. Lipids 1992;27:181-186.
10. Hartog MGL, Feskens EJM, Hollman PCH, Katan MB, Kromhouy D: Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study. Lancet 1993;342:1007-1011.
11. Jung UJ, Lee MK, Jeong KS, Choi MS: The hypoglycemic effects of hesperidin and naringin are partly mediated by hepatic glucose-regulating enzymes in C57BL/KsJ-db/db mice. J Nutr 2004;134:2499-2503.
12. Lee JS, Lee MK, Ha TY, et al.: Supplementation of whole persimmon leaf improves lipid profiles and suppresses body weight gain in rats fed high-fat diet. Food Chem Toxicol 2006;44:1875-1883.
13. Bok SH, Lee SH, Park YB, et al.: Plasma and hepatic cholesterol and hepatic activities of 3-hydroxy-3-methyl-glutaryl-CoA reductase and acyl CoA:cholesterol transferase are lower in rats fed citrus peel extract or a mixture of citrus bioflavonoids. J Nutr 1999;129:1182-1185.
14. th ed. Association of Official Analytical Chemists, Washington, DC, 1995, pp. 22-24.
15. Prosky L, Asp NG, Schweizer TF, Devries JW, Furda I: Determination of insoluble, soluble and total dietary fiber in food and food products interlaboratory study. J Assoc Off Anal Chem 1988;71:1017-1023.
16. Singleton VL, Orthofer R, Lamuela-Raventos RM: Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent. Methods Enzymol 1999;299:152-178.
17. Wolfe K, Wu X, Liu RH: Antioxidant activity of apple peels. J Agric Food Chem 2003;51:609-614.
18. American Institute of Nutrition: Report of the American Institute of Nutrition Ad Hoc Committee on Standards for Nutritional Studies. J Nutr 1977;107:1340-1348.
19. American Institute of Nutrition: Report of Ad Hoc Committee on Standards for Nutritional Studies. J Nutr 1980;110:1717-1726.
20. Allain CC, Poon LS, Chan CS, Richmond W, Fu PC: Enzymatic determination of total serum cholesterol. Clin Chem 1974;20:470-475.
21. Warnick GR, Albers JJ: A comprehensive evaluation of the heparin-manganease precipitation procedure for estimating high density lipoprotein cholesterol. J Lipid Res 1978;19:65-76.
22. McGowan MW, Artiss JD, Strandbergh DR, Zak B: A peroxidase-coupled method for the colorimetric determination of serum triglycerides. Clin Chem 1983;29:538-542.
23. Folch J, Lees M, Sloan-Stanley GH: A simple method for isolation and purification of total lipids from animal tissues. J Biol Chem 1957;226:497-509.
24. Hulcher FH, Oleson WH: Simplified spectrophotometric assay for microsomal 3-hydroxy-3-methylglutaryl CoA reductase by measurement of coenzyme A. J Lipid Res 1973;14:625-631.
25. Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-254.
26. Shapiro DJ, Nordstrom JL, Mitschelen JJ, Rodwell VW, Schimke RT: Micro assay for 3-hydroxy-3-methylglutaryl-CoA reductase in rat liver and in L-cell fibroblasts. Biochim Biophys Acta 1974;370:369-377.
27. Erickson SK, Schrewsbury MA, Brooks C, Meyer DJ: Rat liver acyl-coenzyme A:cholesterol acyltransferase: its regulation in vivo and some of its properties in vitro. J Lipid Res 1980;21:930-941.
28. Gillies PJ, Rathgeb KA, Perri MA, Robinson CS: Regulation of acyl-CoA:cholesterol acyltransferase activity in normal controland atherosclerotic rabbit aortas: role of a cholesterol substrate pool. Exp Mol Pathol 1986;44:320-339.
29. Nilsson-Ehle P, Schotz MC: A stable, radioactive substrate emulsion for assay of lipoprotein lipase. J Lipid Res 1976:17:536-541.
30. Belfrage P, Vaughan M: Simple liquid-liquid partition system for isolation of labeled oleic acid from mixtures with glycerides. J Lipid Res 1969;10:341-344.
31. Downs JR, Clearfield M, Weis S, et al.: Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPA/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study. JAMA 1998;279:1615-1622.
32. Stangle V, Lorenz M, Stangl K: The role of tea and tea flavonoids in cardiovascular health. Mol Nutr Food Res 2006;50:218-228.
33. Ghasi S, Nwobodo E, Ofili JO: Hypocholesterolemic effects of crude extract of leaf of Moringa oleifera Lam in high-fat diet fed wistar rats. J Ethnopharmacol 2000;69:21-25.
34. Jo C, Son JH, Shin MG, Byun MW: Irradiation effects on color and functional properties of persimmon (Diospyros kaki L. folium) leaf extract and licorice (Glycyrrhiza uralensis Fischer) root extract during storage. Radiat Phys Chem 2003;67:143-148.
35. Matsuok T, Ito S: The chemical structure of kaki tannin from immature fruit of the persimmon (Dispyros kaki L.). Agric Biol Chem 1978;42:1637-1643.
36. Choi C: Studies on Investigation into Biologically Activated Substances from Korean Persimmon Leaves and Developing High Function Beverages. Report of the Ministry of Agriculture and Forestry. Ministry of Agriculture and Forestry, Seoul, 2000, pp. 149-150.
37. Park SY, Park SH, Jeon SM, et al.: Effect of rutin and tanic acid supplements on cholesterol metabolism in rats. Nutr Res 2002;22:283-295.
38. Gorinstein S, Kulasek GW, Bartnikowska E, et al.: The effects of diets, supplemented with either whole persimmon or phenolfree persimmon, on rats fed cholesterol. Food Chem 2000;70:303-308.
39. Heckers H, Zielinsky D: Fecal composition and colonic function due to dietary variables. Pract Gastroenterol 1984;(Suppl):24-39.
40. Marlett JA, Li BU, Patrow CJ, Bass P: Comparative laxation of psyllium with and without senna in an ambulatory constipated population. Am J Gastroenterol 1987;82:333-337.
41. Fernandez ML, Ruiz LR, Conde AK: Psyllium reduces plasma LDL in guinea pigs by altering hepatic cholesterol homeostasis. J Lipid Res 1995;36:1128-1138.
42. Terpstra AH, Lapre JA, de Vries HT, Beynen AC: Hypocholesterolemic effect of dietary psyllium in female rats. Ann Nutr Metab 2000;44:223-228.
43. Hansen SH: The role of taurine in diabetes and the development of diabetic complications. Diabetes Metab Res Rev 2001;17:330-346.
44. Yokogoshi H, Mochizuki H, Nanami K, Hida Y, Miyachi F, Oda H: Dietary taurine enhances cholesterol degradation and reduces serum and liver cholesterol concentration in rats fed a high-cholesterol diet. J Nutr 1999;129:1705-1712.
45. Havsteen B: Flavonoids, a class of natural product high pharmacological potency. Biochem Pharmacol 1983;32:1141-1148.
46. Monforte MT, Trovato A, Kirjavainen S, Forestieri AM, Galati EM, Lo Curt RB: Biological effects of hesperidin, a citrus flavonoid. (Note II): Hypolipidemic activity on experimental hypercholesterolemia in rat. Farmaco 1995;50:595-599.
47. Kurowska EM, Borradaile NM, Spence JD, Carroll KK: Hypocholesterolemic effects of dietary citrus juices in rabbits. Nutr Res 2000;20:121-129.
48. Jeon SM, Park YB, Choi MS: Antihypercholesterolemic property of naringin alters plasma and tissue lipids, cholesterol-regulating enzymes, fecal sterol and tissue morphology in rabbits. Clin Nutr 2004;23:1025-1034.
49. Kim HS, Park YS, Kim CI: Changes of serum lipid profiles after eating Lycii Fructus in rats fed high fat diet. Korean J Nutr 1998;31:263-270.
50. Moyers SB, Kumarm NB: Green tea polyphenols and cancer chemoprevention: multiple mechanisms and endpoints for phase II trials. Nutr Rev 2004;62:204-211.
51. Sueok N, Suganumam M, Sueok AE, et al.: A new function of green tea: prevention of lifestyle-related diseases. Ann N Y Acad Sci 2001;928:274-280.
52. Chung CH, Yoo YS: Effect of aqueous green tea extracts with α-tocoperol and lecithin on the lipid metabolism in serum and liver of rats. Korean J Nutr 1995;28:15-22.