Activity of the Bcr GTPase-activating domain is regulated through direct protein/protein interaction with the Rho guanine nucleotide dissociation inhibitor

Journal of Biological Chemistry

Volumn 283, Issue 6, 2008, Pages 3023-3030

  Kweon, Soo Mi ^a   Young, Jin Cho ^a,c   Minoo, Parviz ^b   Groffen, John ^a,b   Heisterkamp, Nora ^a,b  

^a CHILDREN S HOSPITAL LOS ANGELES   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COORDINATION REACTIONS; DISSOCIATION; FLOW INTERACTIONS; GALLIUM ALLOYS; NUCLEIC ACIDS; NUCLEOTIDES; PROTEINS;

ACTIVATING PROTEINS; BOUND STATES; CONTROLLING ACTIVITIES; DO-MAINS; GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; IN CELLS; NULL MUTANTS; PROTEIN COMPLEXES; PROTEIN/PROTEIN INTERACTIONS; RAC GTPASES;

POSITIVE IONS;

BREAKPOINT CLUSTER REGION PROTEIN; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; GUANOSINE TRIPHOSPHATE; PROTEIN INHIBITOR; RAC PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHO GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR ALPHA; UNCLASSIFIED DRUG; BCR PROTEIN, HUMAN; GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR; RHO GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CELL LYSATE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; GENE MUTATION; HYDROLYSIS; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; ANIMAL; CHEMISTRY; CHO CELL; CRICETULUS; GENE EXPRESSION REGULATION; HAMSTER; HUMAN; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE;

MUS;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; GENE EXPRESSION REGULATION; GTP PHOSPHOHYDROLASES; GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-BCR; RHO GTP-BINDING PROTEINS;

EID: 41249100873     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M705513200     Document Type: Article

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