메뉴 건너뛰기




Volumn 32, Issue 4, 2008, Pages 593-599

Family history of alcoholism is associated with lower 5-HT2A receptor binding in the prefrontal cortex

Author keywords

Genotyping; Human; Postmortem; Quantitative Autoradiography; Serotonin

Indexed keywords

KETANSERIN; SEROTONIN 2A RECEPTOR; TRITIUM;

EID: 41149171360     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2007.00610.x     Document Type: Article
Times cited : (21)

References (51)
  • 1
    • 0027332691 scopus 로고
    • Quantitative autoradiography of alpha 1- and alpha 2-adrenergic receptors in the cerebral cortex of controls and suicide victims
    • Arango V, Ernsberger P, Sved AF, Mann JJ (1993) Quantitative autoradiography of alpha 1- and alpha 2-adrenergic receptors in the cerebral cortex of controls and suicide victims. Brain Res 630: 271 282.
    • (1993) Brain Res , vol.630 , pp. 271-282
    • Arango, V.1    Ernsberger, P.2    Sved, A.F.3    Mann, J.J.4
  • 2
    • 0035669353 scopus 로고    scopus 로고
    • Serotonin 1A receptors, serotonin transporter binding and serotonin transporter mRNA expression in the brainstem of depressed suicide victims
    • Arango V, Underwood MD, Boldrini M, Tamir H, Kassir SA, Hsiung S, Chen JJX, Mann JJ (2001) Serotonin 1A receptors, serotonin transporter binding and serotonin transporter mRNA expression in the brainstem of depressed suicide victims. Neuropsychopharmacology 25: 892 903.
    • (2001) Neuropsychopharmacology , vol.25 , pp. 892-903
    • Arango, V.1    Underwood, M.D.2    Boldrini, M.3    Tamir, H.4    Kassir, S.A.5    Hsiung, S.6    Chen, J.J.X.7    Mann, J.J.8
  • 3
    • 0029134538 scopus 로고
    • Localized alterations in pre- and postsynaptic serotonin binding sites in the ventrolateral prefrontal cortex of suicide victims
    • Arango V, Underwood MD, Gubbi AV, Mann JJ (1995) Localized alterations in pre- and postsynaptic serotonin binding sites in the ventrolateral prefrontal cortex of suicide victims. Brain Res 688: 121 133.
    • (1995) Brain Res , vol.688 , pp. 121-133
    • Arango, V.1    Underwood, M.D.2    Gubbi, A.V.3    Mann, J.J.4
  • 4
    • 0029926044 scopus 로고    scopus 로고
    • Chronic alcoholics without Wernicke-Korsakoff syndrome or cirrhosis do not lose serotonergic neurons in the dorsal raphe nucleus
    • Baker KG, Halliday GM, Kril JJ, Harper CG (1996) Chronic alcoholics without Wernicke-Korsakoff syndrome or cirrhosis do not lose serotonergic neurons in the dorsal raphe nucleus. Alcohol Clin Exp Res 20: 61 66.
    • (1996) Alcohol Clin Exp Res , vol.20 , pp. 61-66
    • Baker, K.G.1    Halliday, G.M.2    Kril, J.J.3    Harper, C.G.4
  • 5
    • 0028048701 scopus 로고
    • Neuroendocrine evidence for reduced serotonergic neurotransmission during heavy drinking
    • Balldin J, Berggren U, Engel J, Eriksson M (1994) Neuroendocrine evidence for reduced serotonergic neurotransmission during heavy drinking. Alcohol Clin Exp Res 18: 822 825.
    • (1994) Alcohol Clin Exp Res , vol.18 , pp. 822-825
    • Balldin, J.1    Berggren, U.2    Engel, J.3    Eriksson, M.4
  • 7
    • 0019826345 scopus 로고
    • Cerebrospinal fluid 5-hydroxyindoleacetic acid as an index of central serotonergic processes
    • Banki CM, Molnar G (1981) Cerebrospinal fluid 5-hydroxyindoleacetic acid as an index of central serotonergic processes. Psychiatry Res 5: 23 32.
    • (1981) Psychiatry Res , vol.5 , pp. 23-32
    • Banki, C.M.1    Molnar, G.2
  • 9
    • 0033061430 scopus 로고    scopus 로고
    • Autoradiographic analysis of 5-HT2A binding sites in the brain of Sardinian alcohol-preferring and nonpreferring rats
    • Ciccocioppo R, Angeletti S, Colombo G, Gessa G, Massi M (1999) Autoradiographic analysis of 5-HT2A binding sites in the brain of Sardinian alcohol-preferring and nonpreferring rats. Eur J Pharmacol 373: 13 19.
    • (1999) Eur J Pharmacol , vol.373 , pp. 13-19
    • Ciccocioppo, R.1    Angeletti, S.2    Colombo, G.3    Gessa, G.4    Massi, M.5
  • 10
    • 0031776553 scopus 로고    scopus 로고
    • Serotonin is reduced in the frontal cortex of sardinian ethanol-preferring rats
    • Devoto P, Colombo G, Stefanini E, Gessa GL (1998) Serotonin is reduced in the frontal cortex of sardinian ethanol-preferring rats. Alcohol Alcohol 33: 226 229.
    • (1998) Alcohol Alcohol , vol.33 , pp. 226-229
    • Devoto, P.1    Colombo, G.2    Stefanini, E.3    Gessa, G.L.4
  • 11
    • 0029868373 scopus 로고    scopus 로고
    • Early-onset alcoholics have lower cerebrospinal fluid 5-hydroxyindoleacetic acid levels than late-onset alcoholics
    • Fils-Aime ML, Eckardt MJ, George DT, Brown GL, Mefford I, Linnoila M (1996) Early-onset alcoholics have lower cerebrospinal fluid 5-hydroxyindoleacetic acid levels than late-onset alcoholics. Arch Gen Psychiatry 53: 211 216.
    • (1996) Arch Gen Psychiatry , vol.53 , pp. 211-216
    • Fils-Aime, M.L.1    Eckardt, M.J.2    George, D.T.3    Brown, G.L.4    Mefford, I.5    Linnoila, M.6
  • 12
    • 0025232511 scopus 로고
    • Serotonin receptors: Clinical implications
    • Glennon RA (1990) Serotonin receptors: clinical implications. Neurosci Biobehav Rev 14: 35 47.
    • (1990) Neurosci Biobehav Rev , vol.14 , pp. 35-47
    • Glennon, R.A.1
  • 13
    • 0029081968 scopus 로고
    • Identifying alcoholism vulnerability alleles
    • Goldman D (1995) Identifying alcoholism vulnerability alleles. Alcohol Clin Exp Res 19: 824 831.
    • (1995) Alcohol Clin Exp Res , vol.19 , pp. 824-831
    • Goldman, D.1
  • 14
    • 0031881598 scopus 로고    scopus 로고
    • The neuropathology of alcohol-specific brain damage, or does alcohol damage the brain?
    • Harper C (1998) The neuropathology of alcohol-specific brain damage, or does alcohol damage the brain? J Neuropathol Exp Neurol 57: 101 110.
    • (1998) J Neuropathol Exp Neurol , vol.57 , pp. 101-110
    • Harper, C.1
  • 15
    • 0024420408 scopus 로고
    • Patterns of neuronal loss in the cerebral cortex in chronic alcoholic patients
    • Harper C, Kril J (1989) Patterns of neuronal loss in the cerebral cortex in chronic alcoholic patients. J Neurol Sci 92: 81 89.
    • (1989) J Neurol Sci , vol.92 , pp. 81-89
    • Harper, C.1    Kril, J.2
  • 16
    • 0025364553 scopus 로고
    • Neuropathology of alcoholism
    • Harper CG, Kril JJ (1990) Neuropathology of alcoholism. Alcohol Alcohol 25: 207 216.
    • (1990) Alcohol Alcohol , vol.25 , pp. 207-216
    • Harper, C.G.1    Kril, J.J.2
  • 17
    • 0023151980 scopus 로고
    • Are we drinking our neurons away?
    • Harper C, Kril J, Daly J (1987) Are we drinking our neurons away? Br Med J 294: 534 536.
    • (1987) Br Med J , vol.294 , pp. 534-536
    • Harper, C.1    Kril, J.2    Daly, J.3
  • 18
    • 0028556248 scopus 로고
    • 1994 Draft DSM-IV criteria for alcohol use disorders: Comparison to DSM-III-R and implications
    • Hasin D, Grant B (1994a) 1994 Draft DSM-IV criteria for alcohol use disorders: comparison to DSM-III-R and implications. Alcohol Clin Exp Res 18: 1348 1353.
    • (1994) Alcohol Clin Exp Res , vol.18 , pp. 1348-1353
    • Hasin, D.1    Grant, B.2
  • 19
    • 0028297765 scopus 로고
    • Nosological comparisons of DSM-III-R and DSM-IV alcohol abuse and dependence in a clinical facility: Comparison with the 1988 National Health Interview Survey results
    • Hasin DS, Grant B (1994b) Nosological comparisons of DSM-III-R and DSM-IV alcohol abuse and dependence in a clinical facility: comparison with the 1988 National Health Interview Survey results. Alcohol Clin Exp Res 18: 272 279.
    • (1994) Alcohol Clin Exp Res , vol.18 , pp. 272-279
    • Hasin, D.S.1    Grant, B.2
  • 20
    • 0035371383 scopus 로고    scopus 로고
    • Right amygdala volume in adolescent and young adult offspring from families at high risk for developing alcoholism
    • Hill SY, De Bellis MD, Keshavan MS, Lowers L, Shen S, Hall J, Pitts T (2001) Right amygdala volume in adolescent and young adult offspring from families at high risk for developing alcoholism. Biol Psychiatry 49: 894 905.
    • (2001) Biol Psychiatry , vol.49 , pp. 894-905
    • Hill, S.Y.1    De Bellis, M.D.2    Keshavan, M.S.3    Lowers, L.4    Shen, S.5    Hall, J.6    Pitts, T.7
  • 21
    • 0034606206 scopus 로고    scopus 로고
    • Association of 5HT2A receptor gene polymorphism and alcohol abuse with behavior problems
    • Hwu HG, Chen CH (2000) Association of 5HT2A receptor gene polymorphism and alcohol abuse with behavior problems. Am J Med Genet 96: 797 800.
    • (2000) Am J Med Genet , vol.96 , pp. 797-800
    • Hwu, H.G.1    Chen, C.H.2
  • 22
    • 1842525769 scopus 로고    scopus 로고
    • Neurobehavioral effects in rat pups whose sires were exposed to alcohol
    • Jamerson PA, Wulser MJ, Kimler BF (2004) Neurobehavioral effects in rat pups whose sires were exposed to alcohol. Brain Res Dev Brain Res 149: 103 111.
    • (2004) Brain Res Dev Brain Res , vol.149 , pp. 103-111
    • Jamerson, P.A.1    Wulser, M.J.2    Kimler, B.F.3
  • 23
    • 0029965048 scopus 로고    scopus 로고
    • Validity of DSM-III-R diagnosis by psychological autopsy: A comparison with clinician ante-mortem diagnosis
    • Kelly TM, Mann JJ (1996) Validity of DSM-III-R diagnosis by psychological autopsy: a comparison with clinician ante-mortem diagnosis. Acta Psychiatr Scand 94: 337 343.
    • (1996) Acta Psychiatr Scand , vol.94 , pp. 337-343
    • Kelly, T.M.1    Mann, J.J.2
  • 25
    • 0038135176 scopus 로고    scopus 로고
    • Cigarette smoking, suicidal behavior, and serotonin function in major psychiatric disorders
    • Malone KM, Waternaux C, Haas GL, Cooper TB, Li S, Mann JJ (2003) Cigarette smoking, suicidal behavior, and serotonin function in major psychiatric disorders. Am J Psychiatry 160: 773 779.
    • (2003) Am J Psychiatry , vol.160 , pp. 773-779
    • Malone, K.M.1    Waternaux, C.2    Haas, G.L.3    Cooper, T.B.4    Li, S.5    Mann, J.J.6
  • 29
    • 33750308133 scopus 로고    scopus 로고
    • Reduced glial and neuronal packing density in the orbitofrontal cortex in alcohol dependence and its relationship with suicide and duration of alcohol dependence
    • Miguel-Hidalgo JJ, Overholser JC, Meltzer HY, Stockmeier CA, Rajkowska G (2006) Reduced glial and neuronal packing density in the orbitofrontal cortex in alcohol dependence and its relationship with suicide and duration of alcohol dependence. Alcohol Clin Exp Res 30: 1845 1855.
    • (2006) Alcohol Clin Exp Res , vol.30 , pp. 1845-1855
    • Miguel-Hidalgo, J.J.1    Overholser, J.C.2    Meltzer, H.Y.3    Stockmeier, C.A.4    Rajkowska, G.5
  • 30
    • 0027335559 scopus 로고
    • 2 Receptor blockade by amperozide suppresses ethanol drinking in genetically preferring rats
    • 2 Receptor blockade by amperozide suppresses ethanol drinking in genetically preferring rats. Pharmacol Biochem Behav 45: 741 747.
    • (1993) Pharmacol Biochem Behav , vol.45 , pp. 741-747
    • Myers, R.D.1    Lankford, M.F.2    Björk, A.3
  • 32
    • 0030657594 scopus 로고    scopus 로고
    • Selective inhibition of alcohol intake in diverse alcohol-preferring rat strains by the 5-HT2A antagonists amperozide and FG 5974
    • Overstreet DH, McArthur RA, Rezvani AH, Post C (1997) Selective inhibition of alcohol intake in diverse alcohol-preferring rat strains by the 5-HT2A antagonists amperozide and FG 5974. Alcohol Clin Exp Res 21: 1448 1454.
    • (1997) Alcohol Clin Exp Res , vol.21 , pp. 1448-1454
    • Overstreet, D.H.1    McArthur, R.A.2    Rezvani, A.H.3    Post, C.4
  • 33
    • 0027071703 scopus 로고
    • Effect of ethanol administration and withdrawal on serotonin receptor subtypes and receptor-mediated phosphoinositide hydrolysis in rat brain
    • Pandey SC, Piano MR, Schwertz DW, Davis JM, Pandey GN (1992) Effect of ethanol administration and withdrawal on serotonin receptor subtypes and receptor-mediated phosphoinositide hydrolysis in rat braAlcohol Clin Exp Res 16: 1110 1116.
    • (1992) Alcohol Clin Exp Res , vol.16 , pp. 1110-1116
    • Pandey, S.C.1    Piano, M.R.2    Schwertz, D.W.3    Davis, J.M.4    Pandey, G.N.5
  • 34
    • 4444232862 scopus 로고    scopus 로고
    • The -1438A/G polymorphism in the 5-hydroxytryptamine type 2A receptor gene affects promoter activity
    • Parsons MJ, D'Souza UM, Arranz MJ, Kerwin RW, Makoff AJ (2004) The -1438A/G polymorphism in the 5-hydroxytryptamine type 2A receptor gene affects promoter activity. Biol Psychiatry 56: 406 410.
    • (2004) Biol Psychiatry , vol.56 , pp. 406-410
    • Parsons, M.J.1    D'Souza, U.M.2    Arranz, M.J.3    Kerwin, R.W.4    Makoff, A.J.5
  • 35
    • 0004601156 scopus 로고
    • Multiple Serotonin Receptors in the Human Brain
    • Mendelsohn, F.A.O., Paxinos, G. eds. pp. Academic Press, New York.
    • Pazos A, González AM, Waeber C, Palacios JM (1991) Multiple Serotonin Receptors in the Human Brain, in Receptors in the Human Nervous System (Mendelsohn FAO, Paxinos G eds pp 71 101. Academic Press, New York.
    • (1991) Receptors in the Human Nervous System , pp. 71-101
    • Pazos, A.1    González, A.M.2    Waeber, C.3    Palacios, J.M.4
  • 36
    • 0033846865 scopus 로고    scopus 로고
    • Sex-specific genetic influences on the comorbidity of alcoholism and major depression in a population-based sample of US twins
    • Prescott CA, Aggen SH, Kendler KS (2000) Sex-specific genetic influences on the comorbidity of alcoholism and major depression in a population-based sample of US twins. Arch Gen Psychiatry 57: 803 811.
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 803-811
    • Prescott, C.A.1    Aggen, S.H.2    Kendler, K.S.3
  • 38
    • 0025844780 scopus 로고
    • Depression among alcoholics. Relationship to clinical and cerebrospinal fluid variables
    • Roy A, DeJong J, Lamparski D, George T, Linnoila M (1991) Depression among alcoholics. Relationship to clinical and cerebrospinal fluid variables. Arch Gen Psychiatry 48: 428 432.
    • (1991) Arch Gen Psychiatry , vol.48 , pp. 428-432
    • Roy, A.1    Dejong, J.2    Lamparski, D.3    George, T.4    Linnoila, M.5
  • 42
    • 34247109567 scopus 로고    scopus 로고
    • Morphometry of dorsal raphe nucleus serotonergic neurons in alcoholism
    • Underwood MD, Mann JJ, Arango V (2007) Morphometry of dorsal raphe nucleus serotonergic neurons in alcoholism. Alcohol Clin Exp Res 31: 837 845.
    • (2007) Alcohol Clin Exp Res , vol.31 , pp. 837-845
    • Underwood, M.D.1    Mann, J.J.2    Arango, V.3
  • 43
  • 46
    • 0027330278 scopus 로고
    • 1A receptor in some brain areas of alcohol-preferring (P) rats compared to nonpreferring (NP) rats
    • 1A receptor in some brain areas of alcohol-preferring (P) rats compared to nonpreferring (NP) rats. Pharmacol Biochem Behav 46: 173 177.
    • (1993) Pharmacol Biochem Behav , vol.46 , pp. 173-177
    • Wong, D.T.1    Reid, L.R.2    Li, T.-K.3    Lumeng, L.4
  • 47
    • 0025174810 scopus 로고
    • Higher density of serotonin-1A receptors in the hippocampus and cerebral cortex of alcohol-preferring P rats
    • Wong DT, Threlkeld PG, Lumeng L, Li TK (1990) Higher density of serotonin-1A receptors in the hippocampus and cerebral cortex of alcohol-preferring P rats. Life Sci 46: 231 235.
    • (1990) Life Sci , vol.46 , pp. 231-235
    • Wong, D.T.1    Threlkeld, P.G.2    Lumeng, L.3    Li, T.K.4
  • 49
    • 0025746664 scopus 로고
    • Immunostained serotonergic fibers are decreased in selected brain regions of alcohol-preferring rats
    • Zhou FC, Bledsoe S, Lumeng L, Li T-K (1991) Immunostained serotonergic fibers are decreased in selected brain regions of alcohol-preferring rats. Alcohol 8: 425 431.
    • (1991) Alcohol , vol.8 , pp. 425-431
    • Zhou, F.C.1    Bledsoe, S.2    Lumeng, L.3    Li, T.-K.4
  • 50
    • 0028365749 scopus 로고
    • Reduced serotonergic immunoreactive fibers in the forebrain of alcohol-preferring rats
    • Zhou FC, Bledsoe S, Lumeng L, Li T-K (1994a) Reduced serotonergic immunoreactive fibers in the forebrain of alcohol-preferring rats. Alcohol Clin Exp Res 18: 571 579.
    • (1994) Alcohol Clin Exp Res , vol.18 , pp. 571-579
    • Zhou, F.C.1    Bledsoe, S.2    Lumeng, L.3    Li, T.-K.4
  • 51
    • 0028059985 scopus 로고
    • Serotonergic neurons in the alcohol preferring rats
    • Zhou FC, Pu CF, Murphy J, Lumeng L, Li T-K (1994b) Serotonergic neurons in the alcohol preferring rats. Alcohol 11: 397 403.
    • (1994) Alcohol , vol.11 , pp. 397-403
    • Zhou, F.C.1    Pu, C.F.2    Murphy, J.3    Lumeng, L.4    Li, T.-K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.