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Volumn 28, Issue 9, 2003, Pages 1712-1719

Lower CSF homovanillic acid levels in depressed patients with a history of alcoholism

Author keywords

Alcoholism; Cerebrospinal fluid; Depression; Dopamine; Homovanillic acid

Indexed keywords

4 HYDROXY 3 METHOXYPHENYLETHYLENE GLYCOL; 5 HYDROXYINDOLEACETIC ACID; HOMOVANILLIC ACID; MONOAMINE;

EID: 0141781029     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1300231     Document Type: Article
Times cited : (56)

References (113)
  • 1
    • 0022115857 scopus 로고
    • Higher CSF levels of HVA and 5-HIAA in delusional compared to nondelusional depression
    • Aberg-Wistedt A, Wistedt B, Bertilsson L (1985). Higher CSF levels of HVA and 5-HIAA in delusional compared to nondelusional depression. Arch Gen Psychiatry 42: 925-926.
    • (1985) Arch Gen Psychiatry , vol.42 , pp. 925-926
    • Aberg-Wistedt, A.1    Wistedt, B.2    Bertilsson, L.3
  • 2
    • 0030249351 scopus 로고    scopus 로고
    • Cerebrospinal fluid concentrations of corticotropin-releasing hormone (CRH) and diazepam-binding inhibitor (DBI) during alcohol withdrawal and abstinence
    • Adinoff B, Anton R, Linnoila M, Guidotti A, Nemeroff CB, Bissette G (1996). Cerebrospinal fluid concentrations of corticotropin-releasing hormone (CRH) and diazepam-binding inhibitor (DBI) during alcohol withdrawal and abstinence. Neuropsychopharmacology 15: 288-295.
    • (1996) Neuropsychopharmacology , vol.15 , pp. 288-295
    • Adinoff, B.1    Anton, R.2    Linnoila, M.3    Guidotti, A.4    Nemeroff, C.B.5    Bissette, G.6
  • 3
    • 0029608882 scopus 로고
    • Levels of gamma-aminobutyric acid in cerebrospinal fluid and plasma during alcohol withdrawal
    • Adinoff B, Kramer GL, Petty F (1995). Levels of gamma-aminobutyric acid in cerebrospinal fluid and plasma during alcohol withdrawal. Psychiatry Res 59: 137-144.
    • (1995) Psychiatry Res , vol.59 , pp. 137-144
    • Adinoff, B.1    Kramer, G.L.2    Petty, F.3
  • 4
    • 0026072424 scopus 로고
    • Inverse relationship between CSF TRH concentrations and the TSH response to TRH in abstinent alcohol-dependent patients
    • Adinoff B, Nemeroff CB, Bissette G, Martin PR, Linnoila M (1991). Inverse relationship between CSF TRH concentrations and the TSH response to TRH in abstinent alcohol-dependent patients. Am J Psychiatry 148: 1586-1588.
    • (1991) Am J Psychiatry , vol.148 , pp. 1586-1588
    • Adinoff, B.1    Nemeroff, C.B.2    Bissette, G.3    Martin, P.R.4    Linnoila, M.5
  • 8
    • 0031929016 scopus 로고    scopus 로고
    • Alcohol, aggression and serotonin: Metabolic aspects
    • Badawy AAB (1998). Alcohol, aggression and serotonin: metabolic aspects. Alcohol Alcoholism 33: 66-72.
    • (1998) Alcohol Alcoholism , vol.33 , pp. 66-72
    • Badawy, A.A.B.1
  • 9
    • 76549195945 scopus 로고
    • Factor analysis of some psychometric measures of impulsiveness and anxiety
    • Barratt ES (1965). Factor analysis of some psychometric measures of impulsiveness and anxiety. Psychol Rep 16: 547-554.
    • (1965) Psychol Rep , vol.16 , pp. 547-554
    • Barratt, E.S.1
  • 10
    • 0028961903 scopus 로고
    • Personality-environment constellations and alcohol use: A process-oriented study of intraindividual change during adolescence
    • Bates ME, Labouvie EW (1995). Personality-environment constellations and alcohol use: a process-oriented study of intraindividual change during adolescence. Psychol Addict Behav 9: 23-35.
    • (1995) Psychol Addict Behav , vol.9 , pp. 23-35
    • Bates, M.E.1    Labouvie, E.W.2
  • 11
    • 0018771454 scopus 로고
    • Assessment of suicidal intention: The scale for suicide ideation
    • Beck AT, Kovacs M, Weissman A (1979). Assessment of suicidal intention: the scale for suicide ideation. J Consult Clin Psychol 47: 343-352.
    • (1979) J Consult Clin Psychol , vol.47 , pp. 343-352
    • Beck, A.T.1    Kovacs, M.2    Weissman, A.3
  • 12
    • 0016379354 scopus 로고
    • Cross-validation of the suicidal intent scale
    • Beck RW, Morris JB, Beck AT (1974a). Cross-validation of the suicidal intent scale. Psychol Rep 34: 445-446.
    • (1974) Psychol Rep , vol.34 , pp. 445-446
    • Beck, R.W.1    Morris, J.B.2    Beck, A.T.3
  • 15
    • 0028308789 scopus 로고
    • The prevalence and distribution of major depression in a national community sample: The National Comorbidity Survey
    • Blazer DG, Kessler RC, McGonagle KA, Swartz MS (1994). The prevalence and distribution of major depression in a national community sample: the National Comorbidity Survey. Am J Psychiatry 151: 979-986.
    • (1994) Am J Psychiatry , vol.151 , pp. 979-986
    • Blazer, D.G.1    Kessler, R.C.2    McGonagle, K.A.3    Swartz, M.S.4
  • 16
    • 0020385151 scopus 로고
    • Endorphin levels in human cerebrospinal fluid during alcohol intoxication and withdrawal
    • Borg S, Kvande H, Rydberg U, Terenius L, Wahlstrom A (1982). Endorphin levels in human cerebrospinal fluid during alcohol intoxication and withdrawal. Psychopharmacology (Berl) 78: 101-103.
    • (1982) Psychopharmacology (Berl) , vol.78 , pp. 101-103
    • Borg, S.1    Kvande, H.2    Rydberg, U.3    Terenius, L.4    Wahlstrom, A.5
  • 17
    • 0015261453 scopus 로고
    • Clinical measurements of central dopamine and 5-hydroxytryptamine metabolism: Reliability and interpretation of cerebrospinal fluid acid monoamine metabolite measures
    • Bowers Jr M (1972). Clinical measurements of central dopamine and 5-hydroxytryptamine metabolism: reliability and interpretation of cerebrospinal fluid acid monoamine metabolite measures. Neuropharmacology 11: 101-111.
    • (1972) Neuropharmacology , vol.11 , pp. 101-111
    • Bowers Jr., M.1
  • 21
    • 0017325030 scopus 로고
    • Correlation of clinical symptoms, HVA and 5-HIAA in csf and plasma L-DOPA in Parkinsonian patients treated with L-DOPA and L-DOPA+RO 4-4602
    • Campanella G, Algeri S, Cerletti C, Dolfini E, Jori A, Rinaldi F (1977). Correlation of clinical symptoms, HVA and 5-HIAA in csf and plasma L-DOPA in Parkinsonian patients treated with L-DOPA and L-DOPA+RO 4-4602. Eur J Clin Pharmacol 11: 255-261.
    • (1977) Eur J Clin Pharmacol , vol.11 , pp. 255-261
    • Campanella, G.1    Algeri, S.2    Cerletti, C.3    Dolfini, E.4    Jori, A.5    Rinaldi, F.6
  • 22
    • 0031279496 scopus 로고    scopus 로고
    • Personality differences predict health-risk behaviors in young adulthood: Evidence from a longitudinal study
    • Caspi A, Begg D, Dickson N, Harrington H, Langley J, Moffitt TE et al (1997). Personality differences predict health-risk behaviors in young adulthood: evidence from a longitudinal study. J Pers Soc Psychol 73: 1052-1063.
    • (1997) J Pers Soc Psychol , vol.73 , pp. 1052-1063
    • Caspi, A.1    Begg, D.2    Dickson, N.3    Harrington, H.4    Langley, J.5    Moffitt, T.E.6
  • 23
    • 0031793778 scopus 로고    scopus 로고
    • CSF monoamine metabolites in relation to the diagnostic interview for borderline patients (DIB)
    • Chotai J, Kullgren G, Asberg M (1998). CSF monoamine metabolites in relation to the diagnostic interview for borderline patients (DIB). Neuropsychobiology 38: 207-212.
    • (1998) Neuropsychobiology , vol.38 , pp. 207-212
    • Chotai, J.1    Kullgren, G.2    Asberg, M.3
  • 24
    • 0023777831 scopus 로고
    • Childhood personality predicts alcohol abuse in young adults
    • Cloninger CR, Sigvardsson S, Bohman M (1988). Childhood personality predicts alcohol abuse in young adults. Alcohol Clin Exp Res 12: 494-505.
    • (1988) Alcohol Clin Exp Res , vol.12 , pp. 494-505
    • Cloninger, C.R.1    Sigvardsson, S.2    Bohman, M.3
  • 28
    • 13244288867 scopus 로고    scopus 로고
    • Relapse in violent crime in relation to cerebrospinal fluid monoamine metabolites (5-HIAA, HVA and HMPG) in male forensic psychiatric patients convicted of murder: A 16-year follow-up
    • Daderman AM, Lidberg L (2002). Relapse in violent crime in relation to cerebrospinal fluid monoamine metabolites (5-HIAA, HVA and HMPG) in male forensic psychiatric patients convicted of murder: a 16-year follow-up. Acta Psychiatr Scand 106(Suppl 412): 71-74.
    • (2002) Acta Psychiatr Scand , vol.106 , Issue.412 SUPPL. , pp. 71-74
    • Daderman, A.M.1    Lidberg, L.2
  • 29
    • 0031722219 scopus 로고    scopus 로고
    • Co-morbid depression and drinking outcome in those with alcohol dependence
    • Davidson KM, Blackburn IM (1998). Co-morbid depression and drinking outcome in those with alcohol dependence. Alcohol Alcoholism 33: 482-487.
    • (1998) Alcohol Alcoholism , vol.33 , pp. 482-487
    • Davidson, K.M.1    Blackburn, I.M.2
  • 30
    • 0027184193 scopus 로고
    • Profound decrement of mesolimbic dopaminergic neuronal activity during ethanol withdrawal syndrome in rats: Electrophysiological and biochemical evidence
    • Diana M, Pistis M, Carboni S, Cessa GL, Rossetti ZL (1993). Profound decrement of mesolimbic dopaminergic neuronal activity during ethanol withdrawal syndrome in rats: electrophysiological and biochemical evidence. Proc Natl Acad Sci USA 90: 7966-7969.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7966-7969
    • Diana, M.1    Pistis, M.2    Carboni, S.3    Cessa, G.L.4    Rossetti, Z.L.5
  • 31
    • 0033198794 scopus 로고    scopus 로고
    • Reduced cerebrospinal HVA concentrations and HVA/5-HIAA ratios in suicide attempters. Monoamine metabolites in 120 suicide attempters and 47 controls
    • Engstrom G, Alling C, Blennow K, Regnell G, Traskman-Bendz L (1999). Reduced cerebrospinal HVA concentrations and HVA/5-HIAA ratios in suicide attempters. Monoamine metabolites in 120 suicide attempters and 47 controls. Eur Neuropsychopharmacol 9: 399-405.
    • (1999) Eur Neuropsychopharmacol , vol.9 , pp. 399-405
    • Engstrom, G.1    Alling, C.2    Blennow, K.3    Regnell, G.4    Traskman-Bendz, L.5
  • 32
    • 0025738989 scopus 로고
    • MMPI measures of impulsivity and depression correlate with CSF 5-HIAA and HVA in depression but not schizophrenia
    • Faustman WO, King RJ, Faull KF, Moses Jr JA, Benson KL, Zarcone VP et al (1991). MMPI measures of impulsivity and depression correlate with CSF 5-HIAA and HVA in depression but not schizophrenia. J Affect Disord 22: 235-239.
    • (1991) J Affect Disord , vol.22 , pp. 235-239
    • Faustman, W.O.1    King, R.J.2    Faull, K.F.3    Moses Jr., J.A.4    Benson, K.L.5    Zarcone, V.P.6
  • 33
    • 0029868373 scopus 로고    scopus 로고
    • Early-onset alcoholics have lower cerebrospinal fluid 5-hydroxyindoleacetic acid levels than late-onset alcoholics
    • Fils-Aime ML, Eckardt MJ, George DT, Brown GL, Mefford I, Linnoila M (1996). Early-onset alcoholics have lower cerebrospinal fluid 5-hydroxyindoleacetic acid levels than late-onset alcoholics. Arch Gen Psychiatry 53: 211-216.
    • (1996) Arch Gen Psychiatry , vol.53 , pp. 211-216
    • Fils-Aime, M.L.1    Eckardt, M.J.2    George, D.T.3    Brown, G.L.4    Mefford, I.5    Linnoila, M.6
  • 34
    • 0002134556 scopus 로고    scopus 로고
    • Neurobiological bases of alcohol's psychological effects
    • Leonard KE, Blane HT (eds). Guilford Press: New York
    • Fromme K, D'Amico EJ (1999). Neurobiological bases of alcohol's psychological effects. In: Leonard KE, Blane HT (eds) Psychological Theories of Drinking and Alcoholism. Guilford Press: New York. pp 422-455.
    • (1999) Psychological Theories of Drinking and Alcoholism , pp. 422-455
    • Fromme, K.1    D'Amico, E.J.2
  • 35
    • 0021031926 scopus 로고
    • Cerebrospinal fluid monoamine metabolites during alcohol withdrawal syndrome and recovered state
    • Fujimoto A, Nagao T, Ebara T, Sato M, Otsuki S (1983). Cerebrospinal fluid monoamine metabolites during alcohol withdrawal syndrome and recovered state. Biol Psychiatry 18: 1141-1152.
    • (1983) Biol Psychiatry , vol.18 , pp. 1141-1152
    • Fujimoto, A.1    Nagao, T.2    Ebara, T.3    Sato, M.4    Otsuki, S.5
  • 36
    • 9844252892 scopus 로고    scopus 로고
    • Cerebrospinal fluid neuroendocrinology of alcohol misusers
    • Geracioti Jr TD (1997). Cerebrospinal fluid neuroendocrinology of alcohol misusers. Addict Biol 2: 401-409.
    • (1997) Addict Biol , vol.2 , pp. 401-409
    • Geracioti Jr., T.D.1
  • 37
    • 0028079727 scopus 로고
    • Concentrations of corticotropin-releasing hormone, norepinephrine, MHPG, 5-hydroxyindoleacetic acid, and tryptophan in the cerebrospinal fluid of alcoholic patients: Serial sampling studies
    • Geracioti Jr TD, Loosen PT, Ebert MH, Ekhator NN, Burns D, Nicholson WE et al (1994). Concentrations of corticotropin-releasing hormone, norepinephrine, MHPG, 5-hydroxyindoleacetic acid, and tryptophan in the cerebrospinal fluid of alcoholic patients: serial sampling studies. Neuroendocrinology 60: 635-642.
    • (1994) Neuroendocrinology , vol.60 , pp. 635-642
    • Geracioti Jr., T.D.1    Loosen, P.T.2    Ebert, M.H.3    Ekhator, N.N.4    Burns, D.5    Nicholson, W.E.6
  • 38
    • 0027453381 scopus 로고
    • Cholecystokinin in human cerebrospinal fluid: Concentrations, dynamics, molecular forms and relationship to fasting and feeding in health, depression and alcoholism
    • Geracioti Jr TD, Nicholson WE, Orth DN, Ekhator NN, Loosen PT (1993). Cholecystokinin in human cerebrospinal fluid: concentrations, dynamics, molecular forms and relationship to fasting and feeding in health, depression and alcoholism. Brain Res 629: 260-268.
    • (1993) Brain Res , vol.629 , pp. 260-268
    • Geracioti Jr., T.D.1    Nicholson, W.E.2    Orth, D.N.3    Ekhator, N.N.4    Loosen, P.T.5
  • 40
    • 0035427258 scopus 로고    scopus 로고
    • A longitudinal study of the order of onset of alcohol dependence and major depression
    • Gilman SE, Abraham HD (2001). A longitudinal study of the order of onset of alcohol dependence and major depression. Drug Alcohol Depend 63: 277-286.
    • (2001) Drug Alcohol Depend , vol.63 , pp. 277-286
    • Gilman, S.E.1    Abraham, H.D.2
  • 41
    • 0026615089 scopus 로고
    • D2 dopamine receptor genotype and cerebrospinal fluid homovanillic acid, 5-hydroxyindoleacetic acid and 3-methoxy-4-hydroxyphenylglycol in alcoholics in Finland and the United States
    • Goldman D, Dean M, Brown GL, Bolos AM, Tokola R, Virkkunen M et al (1992). D2 dopamine receptor genotype and cerebrospinal fluid homovanillic acid, 5-hydroxyindoleacetic acid and 3-methoxy-4-hydroxyphenylglycol in alcoholics in Finland and the United States. Acta Psychiatr Scand 86: 351-357.
    • (1992) Acta Psychiatr Scand , vol.86 , pp. 351-357
    • Goldman, D.1    Dean, M.2    Brown, G.L.3    Bolos, A.M.4    Tokola, R.5    Virkkunen, M.6
  • 42
    • 0033842481 scopus 로고    scopus 로고
    • The tonic/phasic model of dopamine system regulation and its implications for understanding alcohol and psychostimulant craving
    • Grace AA (2000). The tonic/phasic model of dopamine system regulation and its implications for understanding alcohol and psychostimulant craving. Addiction 95(Suppl 2): S119-S128.
    • (2000) Addiction , vol.95 , Issue.2 SUPPL.
    • Grace, A.A.1
  • 43
    • 0030763094 scopus 로고    scopus 로고
    • Prevalence and correlates of alcohol use and DSM-IV alcohol dependence in the United States: Results of the national Longitudinal Alcohol Epidemiological Survey
    • Grant BF (1997). Prevalence and correlates of alcohol use and DSM-IV alcohol dependence in the United States: results of the national Longitudinal Alcohol Epidemiological Survey. J Stud Alcohol 58: 464-473.
    • (1997) J Stud Alcohol , vol.58 , pp. 464-473
    • Grant, B.F.1
  • 44
    • 0028950558 scopus 로고
    • Drinking problems and self-reported criminal behavior, arrests and convictions: 1990 US alcohol and 1989 county surveys
    • Greenfield TK, Weisner C (1995). Drinking problems and self-reported criminal behavior, arrests and convictions: 1990 US alcohol and 1989 county surveys. Addiction 90: 361-373.
    • (1995) Addiction , vol.90 , pp. 361-373
    • Greenfield, T.K.1    Weisner, C.2
  • 45
    • 0001026262 scopus 로고    scopus 로고
    • Depressive disorders
    • Tasman A, Kay J, Lieberman JA (eds), WB Saunders Co: Philadelphia
    • Gruenberg AM, Goldstein RD (1997). Depressive disorders. In: Tasman A, Kay J, Lieberman JA (eds) Psychiatry, Vol. 2 WB Saunders Co: Philadelphia. pp 990-1019.
    • (1997) Psychiatry , vol.2 , pp. 990-1019
    • Gruenberg, A.M.1    Goldstein, R.D.2
  • 48
    • 0025137871 scopus 로고
    • Additional psychiatric illness by Diagnostic Interview Schedule in male alcoholics
    • Herz LR, Volicer L, D'Angelo N, Gadish D (1990). Additional psychiatric illness by Diagnostic Interview Schedule in male alcoholics. Compr Psychiatry 31: 72-79.
    • (1990) Compr Psychiatry , vol.31 , pp. 72-79
    • Herz, L.R.1    Volicer, L.2    D'Angelo, N.3    Gadish, D.4
  • 50
    • 18844472139 scopus 로고    scopus 로고
    • Essential fatty acids predict metabolites of serotonin and dopamine in cerebrospinal fluid among healthy control subjects, and early- and late-onset alcoholics
    • Hibbeln JR, Linnoila M, Umhau JC, Rawlings R, George DT, Salem Jr N (1998). Essential fatty acids predict metabolites of serotonin and dopamine in cerebrospinal fluid among healthy control subjects, and early- and late-onset alcoholics. Biol Psychiatry 44: 235-242.
    • (1998) Biol Psychiatry , vol.44 , pp. 235-242
    • Hibbeln, J.R.1    Linnoila, M.2    Umhau, J.C.3    Rawlings, R.4    George, D.T.5    Salem Jr., N.6
  • 54
    • 0027538596 scopus 로고
    • Biogenic amine metabolites in the CSF of patients with late onset and alcoholic ataxias
    • Kaakkola S, Tuomainen P, Mannisto PT, Palo J (1993). Biogenic amine metabolites in the CSF of patients with late onset and alcoholic ataxias. Acta Neurol Scand 87: 309-311.
    • (1993) Acta Neurol Scand , vol.87 , pp. 309-311
    • Kaakkola, S.1    Tuomainen, P.2    Mannisto, P.T.3    Palo, J.4
  • 55
    • 0032478525 scopus 로고    scopus 로고
    • Cerebrospinal fluid homovanillic acid levels are not reduced in early corticobasal degeneration
    • Kanemaru K, Mitani K, Yamanouchi H (1998). Cerebrospinal fluid homovanillic acid levels are not reduced in early corticobasal degeneration. Neurosci Lett 245: 121-122.
    • (1998) Neurosci Lett , vol.245 , pp. 121-122
    • Kanemaru, K.1    Mitani, K.2    Yamanouchi, H.3
  • 56
    • 0026775763 scopus 로고
    • Role of the dopaminergic system in depression
    • Kapur S, Mann JJ (1992). Role of the dopaminergic system in depression. Biol Psychiatry 32: 1-17.
    • (1992) Biol Psychiatry , vol.32 , pp. 1-17
    • Kapur, S.1    Mann, J.J.2
  • 57
    • 0018741013 scopus 로고
    • Changes in the metabolism of biogenic amines in alcoholism - Especially regarding CSF monoamine metabolites and serum DBH activity
    • Kato N, Takahashi S, Tani N, Iwase N, Odani K (1979). Changes in the metabolism of biogenic amines in alcoholism - especially regarding CSF monoamine metabolites and serum DBH activity. Alcohol Clin Exp Res 3: 24-27.
    • (1979) Alcohol Clin Exp Res , vol.3 , pp. 24-27
    • Kato, N.1    Takahashi, S.2    Tani, N.3    Iwase, N.4    Odani, K.5
  • 58
    • 0026759536 scopus 로고
    • Neural mechanisms of drug reinforcement
    • Kalivas PW, Samson HH (eds). New York Academy of Sciences: New York
    • Koob GF (1992). Neural mechanisms of drug reinforcement. In: Kalivas PW, Samson HH (eds) The Neurobiology of Drug and Alcohol Addiction. New York Academy of Sciences: New York. pp 171-191.
    • (1992) The Neurobiology of Drug and Alcohol Addiction , pp. 171-191
    • Koob, G.F.1
  • 59
    • 0020604415 scopus 로고
    • CSF and urinary biogenic amines and metabolites in depression and mania. A controlled, univariate analysis
    • Koslow SH, Maas JW, Bowden CL, Davis JM, Hanin I, Javaid J (1983). CSF and urinary biogenic amines and metabolites in depression and mania. A controlled, univariate analysis. Arch Gen Psychiatry 40: 999-1010.
    • (1983) Arch Gen Psychiatry , vol.40 , pp. 999-1010
    • Koslow, S.H.1    Maas, J.W.2    Bowden, C.L.3    Davis, J.M.4    Hanin, I.5    Javaid, J.6
  • 60
    • 0025872673 scopus 로고
    • Personality and cerebrospinal fluid monoamine metabolites in alcoholics and controls
    • Limson R, Goldman D, Roy A, Lamparski D, Ravitz B, Adinoff B et al (1991). Personality and cerebrospinal fluid monoamine metabolites in alcoholics and controls. Arch Gen Psychiatry 48: 437-441.
    • (1991) Arch Gen Psychiatry , vol.48 , pp. 437-441
    • Limson, R.1    Goldman, D.2    Roy, A.3    Lamparski, D.4    Ravitz, B.5    Adinoff, B.6
  • 61
    • 0021834013 scopus 로고
    • Low HVA and normal 5HIAA CSF levels in drug-free schizophrenic patients compared to healthy volunteers: Correlations to symptomatology and family history
    • Lindstrom LH (1985). Low HVA and normal 5HIAA CSF levels in drug-free schizophrenic patients compared to healthy volunteers: correlations to symptomatology and family history. Psychiatry Res 14: 265-273.
    • (1985) Psychiatry Res , vol.14 , pp. 265-273
    • Lindstrom, L.H.1
  • 63
    • 0017753010 scopus 로고
    • Cerebrospinal fluid homovanillic acid in male alcoholics: Effects of disulfiram
    • Major LF, Ballenger JC, Goodwin FK, Brown GL (1977). Cerebrospinal fluid homovanillic acid in male alcoholics: effects of disulfiram. Biol Psychiatry 12: 635-642.
    • (1977) Biol Psychiatry , vol.12 , pp. 635-642
    • Major, L.F.1    Ballenger, J.C.2    Goodwin, F.K.3    Brown, G.L.4
  • 64
    • 0034526273 scopus 로고    scopus 로고
    • Current concepts in the treatment of depression in alcohol-dependent patients
    • McGrath PJ, Nunes EV, Quitkin FM (2000). Current concepts in the treatment of depression in alcohol-dependent patients. Psychiatr Clin North Am 23: 695-711.
    • (2000) Psychiatr Clin North Am , vol.23 , pp. 695-711
    • McGrath, P.J.1    Nunes, E.V.2    Quitkin, F.M.3
  • 65
    • 0027155037 scopus 로고
    • Effects of haloperidol on measures of craving and impaired control in alcoholic subjects
    • Modell JG, Mountz JM, Glaser FB, Lee JY (1993). Effects of haloperidol on measures of craving and impaired control in alcoholic subjects. Alcohol Clin Exp Res 17: 234-240.
    • (1993) Alcohol Clin Exp Res , vol.17 , pp. 234-240
    • Modell, J.G.1    Mountz, J.M.2    Glaser, F.B.3    Lee, J.Y.4
  • 66
    • 0014721817 scopus 로고
    • Cerebral metabolites in cerebrospinal fluid as a biochemical approach to the brain
    • Moir ATB, Aschcroft GW, Crawford TBB, Eccleston D, Guldberg HC (1970). Cerebral metabolites in cerebrospinal fluid as a biochemical approach to the brain. Brain 93: 357-368.
    • (1970) Brain , vol.93 , pp. 357-368
    • Moir, A.T.B.1    Aschcroft, G.W.2    Crawford, T.B.B.3    Eccleston, D.4    Guldberg, H.C.5
  • 67
    • 0030996001 scopus 로고    scopus 로고
    • Global mortality, disability, and the contribution of risk factors: Global burden of disease study
    • Murray CJ, Lopez AD (1997). Global mortality, disability, and the contribution of risk factors: global burden of disease study. Lancet 349: 1436-1442.
    • (1997) Lancet , vol.349 , pp. 1436-1442
    • Murray, C.J.1    Lopez, A.D.2
  • 68
    • 0028770329 scopus 로고
    • Alcohol- and drug-related visits to hospital emergency departments: 1992 national hospital ambulatory medical care survey
    • Nelson CR, Stussman BJ (1994). Alcohol- and drug-related visits to hospital emergency departments: 1992 national hospital ambulatory medical care survey. Adv Data 251: 1-16.
    • (1994) Adv Data , vol.251 , pp. 1-16
    • Nelson, C.R.1    Stussman, B.J.2
  • 69
    • 0002007510 scopus 로고    scopus 로고
    • Pathophysiological basis of psychiatric disorders: Focus on mood disorders and schizophrenia
    • Tasman A, Kay J, Lieberman JA (eds), WB Saunders Co: Philadelphia
    • Nemeroff CB, Musselman DL, Nathan KI, Schatzberg AF, Knable MB, Kllinman JE (1997). Pathophysiological basis of psychiatric disorders: focus on mood disorders and schizophrenia. In: Tasman A, Kay J, Lieberman JA (eds) Psychiatry, Vol. 1 WB Saunders Co: Philadelphia. pp 258-295.
    • (1997) Psychiatry , vol.1 , pp. 258-295
    • Nemeroff, C.B.1    Musselman, D.L.2    Nathan, K.I.3    Schatzberg, A.F.4    Knable, M.B.5    Kllinman, J.E.6
  • 70
    • 0029057338 scopus 로고
    • Neurotransmitter and neuromodulatory mechanism involved in alcohol abuse and alcoholism
    • Nevo I, Hamon M (1995). Neurotransmitter and neuromodulatory mechanism involved in alcohol abuse and alcoholism. Neurochem Int 26: 305-336.
    • (1995) Neurochem Int , vol.26 , pp. 305-336
    • Nevo, I.1    Hamon, M.2
  • 71
    • 0016232316 scopus 로고
    • Alcoholics admitted to four hospitals in England. II. General and cause-specific mortality
    • Nicholls P, Edwards G, Kyle E (1974). Alcoholics admitted to four hospitals in England. II. General and cause-specific mortality. QJ Stud Alcohol 35: 841-855.
    • (1974) QJ Stud Alcohol , vol.35 , pp. 841-855
    • Nicholls, P.1    Edwards, G.2    Kyle, E.3
  • 72
    • 0000890444 scopus 로고    scopus 로고
    • Alcoholism and the dopaminergic system a review
    • Noble EP (1996). Alcoholism and the dopaminergic system A review. Addict Biol 1: 333-348.
    • (1996) Addict Biol , vol.1 , pp. 333-348
    • Noble, E.P.1
  • 73
    • 0029052364 scopus 로고
    • Gradients of CSF monoamine metabolites: A comparison between male and female volunteers
    • Nordin C, Eklundh T, Fernstrom V, Swedin A, Zachau AC (1995). Gradients of CSF monoamine metabolites: a comparison between male and female volunteers. J Psychiatr Res 29: 133-140.
    • (1995) J Psychiatr Res , vol.29 , pp. 133-140
    • Nordin, C.1    Eklundh, T.2    Fernstrom, V.3    Swedin, A.4    Zachau, A.C.5
  • 74
    • 0034056479 scopus 로고    scopus 로고
    • The biology of impulsivity and suicidality
    • Oquendo MA, Mann JJ (2000). The biology of impulsivity and suicidality. Psychiatr Clin North Am 23: 11-25.
    • (2000) Psychiatr Clin North Am , vol.23 , pp. 11-25
    • Oquendo, M.A.1    Mann, J.J.2
  • 76
    • 0032868917 scopus 로고    scopus 로고
    • CSF monoamine metabolite and beta endorphin levels in recently detoxified alcoholics and healthy controls: Prediction of alcohol cue-induced craving?
    • Petrakis IL, Trevisan L, D'Souza C, Gil R, Krasnicki S, Webb E et al (1999). CSF monoamine metabolite and beta endorphin levels in recently detoxified alcoholics and healthy controls: prediction of alcohol cue-induced craving? Alcohol Clin Exp Res 23: 1336-1341.
    • (1999) Alcohol Clin Exp Res , vol.23 , pp. 1336-1341
    • Petrakis, I.L.1    Trevisan, L.2    D'Souza, C.3    Gil, R.4    Krasnicki, S.5    Webb, E.6
  • 77
    • 0031904910 scopus 로고    scopus 로고
    • Serotonin and aggression and the alcohol-aggression relationship
    • Pihl RO, LeMarquand D (1998). Serotonin and aggression and the alcohol-aggression relationship. Alcohol Alcoholism 33: 55-65.
    • (1998) Alcohol Alcoholism , vol.33 , pp. 55-65
    • Pihl, R.O.1    LeMarquand, D.2
  • 78
    • 0035890923 scopus 로고    scopus 로고
    • Aggressivity, suicide attempts, and depression: Relationship to cerebrospinal fluid monoamine metabolite levels
    • Placidi GP, Oquendo MA, Malone KM, Huang YY, Ellis SP, Mann JJ (2001). Aggressivity, suicide attempts, and depression: relationship to cerebrospinal fluid monoamine metabolite levels. Biol Psychiatry 50: 783-791.
    • (2001) Biol Psychiatry , vol.50 , pp. 783-791
    • Placidi, G.P.1    Oquendo, M.A.2    Malone, K.M.3    Huang, Y.Y.4    Ellis, S.P.5    Mann, J.J.6
  • 79
    • 0015538178 scopus 로고
    • Psychomotor activity and cerebrospinal fluid amine metabolites in affective illness
    • Post RM, Kotin J, Goodwin FK, Gordon EK (1973). Psychomotor activity and cerebrospinal fluid amine metabolites in affective illness. Am J Psychiatry 130: 67-72.
    • (1973) Am J Psychiatry , vol.130 , pp. 67-72
    • Post, R.M.1    Kotin, J.2    Goodwin, F.K.3    Gordon, E.K.4
  • 80
    • 0025794368 scopus 로고
    • Ethanol drinking following 6-OHDA lesions of nucleus accumbens and tuberculum olfactorum of the rat
    • Quarfordt SD, Kalmus GW, Myers RD (1991). Ethanol drinking following 6-OHDA lesions of nucleus accumbens and tuberculum olfactorum of the rat. Alcohol 8: 211-217.
    • (1991) Alcohol , vol.8 , pp. 211-217
    • Quarfordt, S.D.1    Kalmus, G.W.2    Myers, R.D.3
  • 81
    • 0026453623 scopus 로고
    • Individual differences in basal cisternal cerebrospinal fluid 5-HIAA and HVA in monkeys. The effects of gender, age, physical characteristics, and matrilineal influences
    • Raleigh MJ, Brammer GL, McGuire MT, Pollack DB, Yuwiler A (1992). Individual differences in basal cisternal cerebrospinal fluid 5-HIAA and HVA in monkeys. The effects of gender, age, physical characteristics, and matrilineal influences. Neuropsychopharmacology 7: 295-304.
    • (1992) Neuropsychopharmacology , vol.7 , pp. 295-304
    • Raleigh, M.J.1    Brammer, G.L.2    McGuire, M.T.3    Pollack, D.B.4    Yuwiler, A.5
  • 83
    • 0036038108 scopus 로고    scopus 로고
    • High correlation between salivary MHPG and CSF MHPG
    • Reuster T, Rilke O, Oehler J (2002). High correlation between salivary MHPG and CSF MHPG. Psychopharmacology 162: 415-418.
    • (2002) Psychopharmacology , vol.162 , pp. 415-418
    • Reuster, T.1    Rilke, O.2    Oehler, J.3
  • 84
    • 0027305458 scopus 로고
    • The neural basis of drug craving: An incentive-sensitization theory of addiction
    • Robinson TE, Berridge KC (1993). The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res Rev 18: 247-291.
    • (1993) Brain Res Rev , vol.18 , pp. 247-291
    • Robinson, T.E.1    Berridge, K.C.2
  • 85
    • 0015932038 scopus 로고
    • Homovanillic acid in cerebrospinal fluid of alcoholics
    • Roos BE, Silfverskiöld BP (1973). Homovanillic acid in cerebrospinal fluid of alcoholics. N Engl J Med 288: 1358-1359.
    • (1973) N Engl J Med , vol.288 , pp. 1358-1359
    • Roos, B.E.1    Silfverskiöld, B.P.2
  • 86
    • 0025774381 scopus 로고
    • Mental disorders among alcoholics. Relationship to age of onset and cerebrospinal fluid neuropeptides
    • Roy A, DeJong J, Lamparski D, Adinoff B, George T, Moore V et al (1991b). Mental disorders among alcoholics. Relationship to age of onset and cerebrospinal fluid neuropeptides. Arch Gen Psychiatry 48: 423-427.
    • (1991) Arch Gen Psychiatry , vol.48 , pp. 423-427
    • Roy, A.1    DeJong, J.2    Lamparski, D.3    Adinoff, B.4    George, T.5    Moore, V.6
  • 87
    • 0025844780 scopus 로고
    • Depression among alcoholics. Relationship to clinical and cerebrospinal fluid variables
    • Roy A, DeJong J, Lamparski D, George T, Linnoila M (1991a). Depression among alcoholics. Relationship to clinical and cerebrospinal fluid variables. Arch Gen Psychiatry 48: 428-432.
    • (1991) Arch Gen Psychiatry , vol.48 , pp. 428-432
    • Roy, A.1    DeJong, J.2    Lamparski, D.3    George, T.4    Linnoila, M.5
  • 90
    • 0025062652 scopus 로고
    • Oral ethanol self-administration: A behavioral pharmacological approach to SND control mechanisms
    • Samson HH, Tolliver GA, Schwarz-Stevens K (1990). Oral ethanol self-administration: a behavioral pharmacological approach to SND control mechanisms. Alcohol 7: 187-191.
    • (1990) Alcohol , vol.7 , pp. 187-191
    • Samson, H.H.1    Tolliver, G.A.2    Schwarz-Stevens, K.3
  • 91
    • 0037864815 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of depression
    • Davis KL, Charney D, Coyle JT, Nemeroff C (eds). Lippincott, Williams & Wilkins: Philadelphia
    • Schatzberg AF, Garlow SL, Nemeroff CB (2002). Molecular and cellular mechanisms of depression. In: Davis KL, Charney D, Coyle JT, Nemeroff C (eds) Neuropsychopharmacology: The Fifth Generation of Progress. Lippincott, Williams & Wilkins: Philadelphia. pp 1039-1050.
    • (2002) Neuropsychopharmacology: The Fifth Generation of Progress , pp. 1039-1050
    • Schatzberg, A.F.1    Garlow, S.L.2    Nemeroff, C.B.3
  • 92
    • 0020511212 scopus 로고
    • Simultaneous determination of 3-methoxy-4-hydroxyphenylglycol, 5-hydroxyindoleacetic acid, and homovanillic acid in cerebrospinal fluid with high-performance liquid chromatography using electrochemical detection
    • Scheinin M, Chang WH, Kirk KL, Linnoila M (1983). Simultaneous determination of 3-methoxy-4-hydroxyphenylglycol, 5-hydroxyindoleacetic acid, and homovanillic acid in cerebrospinal fluid with high-performance liquid chromatography using electrochemical detection. Anal Biochem 131: 246-253.
    • (1983) Anal Biochem , vol.131 , pp. 246-253
    • Scheinin, M.1    Chang, W.H.2    Kirk, K.L.3    Linnoila, M.4
  • 93
    • 0022637199 scopus 로고
    • Genetic and clinical implications of alcoholism and affective disorder
    • Schuckit MA (1986). Genetic and clinical implications of alcoholism and affective disorder. Am J Psychiatry 143: 140-147.
    • (1986) Am J Psychiatry , vol.143 , pp. 140-147
    • Schuckit, M.A.1
  • 94
    • 0021921843 scopus 로고
    • Lumbar cerebrospinal fluid homovanillic acid concentrations are higher in female than male non-human primates
    • Seegal RF (1985). Lumbar cerebrospinal fluid homovanillic acid concentrations are higher in female than male non-human primates. Brain Res 334: 375-379.
    • (1985) Brain Res , vol.334 , pp. 375-379
    • Seegal, R.F.1
  • 95
    • 0027976752 scopus 로고
    • CSF and plasma MHPG, and CSF MHPG index: Pretreatment levels in diagnostic groups and response to somatic treatments
    • Sharma RP, Javaid JI, Faull K, Davis JM, Janicak PG (1994). CSF and plasma MHPG, and CSF MHPG index: pretreatment levels in diagnostic groups and response to somatic treatments. Psychiatry Res 51: 51-60.
    • (1994) Psychiatry Res , vol.51 , pp. 51-60
    • Sharma, R.P.1    Javaid, J.I.2    Faull, K.3    Davis, J.M.4    Janicak, P.G.5
  • 96
    • 33845659837 scopus 로고    scopus 로고
    • Personality and alcoholism: Issues, methods, and etiological processes
    • Leonard KE, Blane HT (eds). Guilford Press: New York
    • Sher KJ, Trull TJ, Bartholow BD, Vieth A (1999). Personality and alcoholism: issues, methods, and etiological processes. In: Leonard KE, Blane HT (eds) Psychological Theories of Drinking and Alcoholism. Guilford Press: New York. pp 54-105.
    • (1999) Psychological Theories of Drinking and Alcoholism , pp. 54-105
    • Sher, K.J.1    Trull, T.J.2    Bartholow, B.D.3    Vieth, A.4
  • 97
    • 0034927718 scopus 로고    scopus 로고
    • CSF studies in violent offenders. I. 5-HIAA as a negative and HVA as a positive predictor of psychopathy
    • Soderstrom H, Blennow K, Manhem A, Forsman A (2001). CSF studies in violent offenders. I. 5-HIAA as a negative and HVA as a positive predictor of psychopathy. J Neural Transm 108: 869-878.
    • (2001) J Neural Transm , vol.108 , pp. 869-878
    • Soderstrom, H.1    Blennow, K.2    Manhem, A.3    Forsman, A.4
  • 98
    • 0034125788 scopus 로고    scopus 로고
    • Alcoholism and depression in a Swedish female population: Co-morbidity and risk factors
    • Spak L, Spak F, Allebeck P (2000). Alcoholism and depression in a Swedish female population: co-morbidity and risk factors. Acta Psychiatr Scand 102: 44-51.
    • (2000) Acta Psychiatr Scand , vol.102 , pp. 44-51
    • Spak, L.1    Spak, F.2    Allebeck, P.3
  • 99
    • 0026567337 scopus 로고
    • Hypnotizability and CSF HVA levels among psychiatric patients
    • Spiegel D, King R (1992). Hypnotizability and CSF HVA levels among psychiatric patients. Biol Psychiatry 31: 95-98.
    • (1992) Biol Psychiatry , vol.31 , pp. 95-98
    • Spiegel, D.1    King, R.2
  • 100
    • 0021889401 scopus 로고
    • Correlations between aminergic metabolites simultaneously obtained from human CSF and brain
    • Stanley M, Träskman-Bendz L, Dorovini-Zis K (1985). Correlations between aminergic metabolites simultaneously obtained from human CSF and brain. Life Sci 37: 1279-1286.
    • (1985) Life Sci , vol.37 , pp. 1279-1286
    • Stanley, M.1    Träskman-Bendz, L.2    Dorovini-Zis, K.3
  • 101
    • 0016181973 scopus 로고
    • CSF monoamine metabolites in alcoholism: A comparative study with depression
    • Takahashi S, Yamane H, Kondo H, Tani N, Kato N (1974). CSF monoamine metabolites in alcoholism: a comparative study with depression. Folia Psychiatr Neurol 28: 347-354.
    • (1974) Folia Psychiatr Neurol , vol.28 , pp. 347-354
    • Takahashi, S.1    Yamane, H.2    Kondo, H.3    Tani, N.4    Kato, N.5
  • 102
    • 0034816697 scopus 로고    scopus 로고
    • Comorbid alcoholism and depression: Treatment issues
    • Thase ME, Salloum IM, Cornelius JD (2001). Comorbid alcoholism and depression: treatment issues. J Clin Psychiatry 62(Suppl 20): 32-41.
    • (2001) J Clin Psychiatry , vol.62 , Issue.20 SUPPL. , pp. 32-41
    • Thase, M.E.1    Salloum, I.M.2    Cornelius, J.D.3
  • 103
    • 0003157486 scopus 로고    scopus 로고
    • Alcohol: Neurobiology
    • Lowinson JH, Ruiz P, Millman RB, Langrod JG (eds), Williams & Wilkins: Baltimore
    • Valenzuela CF, Harris RA (1997). Alcohol: neurobiology. In: Lowinson JH, Ruiz P, Millman RB, Langrod JG (eds) Substance Abuse. A Comprehensive Textbook, 3rd edn Williams & Wilkins: Baltimore. pp 119-142.
    • (1997) Substance Abuse. A Comprehensive Textbook, 3rd Edn , pp. 119-142
    • Valenzuela, C.F.1    Harris, R.A.2
  • 104
    • 0016738258 scopus 로고
    • Dopamine metabolism in depressions, psychoses, and Parkinson's disease: The problem of specificity of biological variables in behavior disorders
    • Van Praag HM, Korf J, Lakke JPWF, Schut T (1975). Dopamine metabolism in depressions, psychoses, and Parkinson's disease: the problem of specificity of biological variables in behavior disorders. Psychol Med 5: 138-146.
    • (1975) Psychol Med , vol.5 , pp. 138-146
    • Van Praag, H.M.1    Korf, J.2    Lakke, J.P.W.F.3    Schut, T.4
  • 105
    • 0003007427 scopus 로고
    • Ethanol effects of CNS dopamine receptors: In vivo binding following voluntary ethanol intake in rats
    • Naranjo CA, Sellers EM (eds). Springer: New York
    • Vavrousek-Jakuba E, Cohen CA, Shoemaker WJ (1992). Ethanol effects of CNS dopamine receptors: in vivo binding following voluntary ethanol intake in rats. In: Naranjo CA, Sellers EM (eds) Novel Pharmacological Interventions for Alcoholism. Springer: New York. pp 372-374.
    • (1992) Novel Pharmacological Interventions for Alcoholism , pp. 372-374
    • Vavrousek-Jakuba, E.1    Cohen, C.A.2    Shoemaker, W.J.3
  • 107
    • 0029947956 scopus 로고    scopus 로고
    • A prospective follow-up study of alcoholic violent offenders and fire setters
    • Virkkunen M, Eggert M, Rawlings R, Linnoila M (1996). A prospective follow-up study of alcoholic violent offenders and fire setters. Arch Gen Psychiatry 53: 523-529.
    • (1996) Arch Gen Psychiatry , vol.53 , pp. 523-529
    • Virkkunen, M.1    Eggert, M.2    Rawlings, R.3    Linnoila, M.4
  • 108
    • 0028053207 scopus 로고
    • CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers
    • Virkkunen M, Rawlings R, Tokola R, Poland RE, Guidotti A, Nemeroff C et al (1994). CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers. Arch Gen Psychiatry 51: 20-27.
    • (1994) Arch Gen Psychiatry , vol.51 , pp. 20-27
    • Virkkunen, M.1    Rawlings, R.2    Tokola, R.3    Poland, R.E.4    Guidotti, A.5    Nemeroff, C.6
  • 109
    • 0001486897 scopus 로고
    • The neuropharmacology of ethanol self-administration
    • Meyer RE, Koob GF, Lewis MJ, Paul SM (eds). Birkhauser: Boston
    • Weiss F, Koob GF (1991). The neuropharmacology of ethanol self-administration. In: Meyer RE, Koob GF, Lewis MJ, Paul SM (eds) Neuropharmacology of Ethanol. Birkhauser: Boston. pp 125-162.
    • (1991) Neuropharmacology of Ethanol , pp. 125-162
    • Weiss, F.1    Koob, G.F.2
  • 110
    • 0029990389 scopus 로고    scopus 로고
    • Ethanol self-administration restores withdrawal-associated deficiencies in accumbal dopamine and 5-hydroxytryptamine release in dependent rats
    • Weiss F, Parsons LH, Schulteis G, Hyytia P, Lorang MT, Bloom FE et al (1996). Ethanol self-administration restores withdrawal-associated deficiencies in accumbal dopamine and 5-hydroxytryptamine release in dependent rats. J Neurosci 16: 3474-3485.
    • (1996) J Neurosci , vol.16 , pp. 3474-3485
    • Weiss, F.1    Parsons, L.H.2    Schulteis, G.3    Hyytia, P.4    Lorang, M.T.5    Bloom, F.E.6
  • 111
    • 0034043946 scopus 로고    scopus 로고
    • Craving for alcohol and dopamine receptor sensitivity in alcohol-dependent men and coutroe subjects
    • Weisbeck GA, Weijers HG, Gross JP (2000). Craving for alcohol and dopamine receptor sensitivity in alcohol-dependent men and coutroe subjects. Neural Transm 107: 691-699.
    • (2000) Neural Transm , vol.107 , pp. 691-699
    • Weisbeck, G.A.1    Weijers, H.G.2    Gross, J.P.3
  • 112
    • 0023685513 scopus 로고
    • CSF monoamine metabolites in patients and controls: Support for a bimodal distribution in major affective disorders
    • Westenberg HG, Verhoeven WM (1988). CSF monoamine metabolites in patients and controls: support for a bimodal distribution in major affective disorders. Acta Psychiatr Scand 78: 541-549.
    • (1988) Acta Psychiatr Scand , vol.78 , pp. 541-549
    • Westenberg, H.G.1    Verhoeven, W.M.2
  • 113
    • 0022743457 scopus 로고
    • Etiology of alcoholism reconsidered: The case for a biopsychosocial process
    • Zucker RA, Gomberg ESL (1986). Etiology of alcoholism reconsidered: the case for a biopsychosocial process. Am Psychol 41: 783-793.
    • (1986) Am Psychol , vol.41 , pp. 783-793
    • Zucker, R.A.1    Gomberg, E.S.L.2


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