메뉴 건너뛰기




Volumn 41, Issue 1, 2008, Pages 47-53

Association between the - 174 G/C promoter polymorphism of the interleukin-6 gene and cardiovascular disease risk factors in Brazilian older women

Author keywords

Brazil; Cardiovascular disease; Cytokine; Elderly; Genetics; Interleukin 6

Indexed keywords

C REACTIVE PROTEIN; CYTOKINE; GLUCOSE; GLYCOSYLATED HEMOGLOBIN; INTERLEUKIN 6;

EID: 41149139303     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X2006005000190     Document Type: Article
Times cited : (32)

References (39)
  • 1
    • 0032524973 scopus 로고    scopus 로고
    • Altered cytokine production in the elderly
    • Rink L, Cakman I, Kirchner H. Altered cytokine production in the elderly. Mech Ageing Dev 1998; 102: 199-209.
    • (1998) Mech Ageing Dev , vol.102 , pp. 199-209
    • Rink, L.1    Cakman, I.2    Kirchner, H.3
  • 2
    • 1542297244 scopus 로고    scopus 로고
    • IL-6 signal transduction and its physiological roles: The signal orchestration model
    • Kamimura D, Ishihara K, Hirano T. IL-6 signal transduction and its physiological roles: the signal orchestration model. Rev Physiol Biochem Pharmacol 2003; 149: 1-38.
    • (2003) Rev Physiol Biochem Pharmacol , vol.149 , pp. 1-38
    • Kamimura, D.1    Ishihara, K.2    Hirano, T.3
  • 3
    • 0032189103 scopus 로고    scopus 로고
    • The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis
    • Fishman D, Faulds G, Jeffery R, Mohamed-Ali V, Yudkin JS, Humphries S, et al. The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J Clin Invest 1998; 102: 1369-1376.
    • (1998) J Clin Invest , vol.102 , pp. 1369-1376
    • Fishman, D.1    Faulds, G.2    Jeffery, R.3    Mohamed-Ali, V.4    Yudkin, J.S.5    Humphries, S.6
  • 6
    • 23044505300 scopus 로고    scopus 로고
    • C-174G polymorphism in the promoter of the interleukin-6 gene is associated with insulin resistance Diabetes
    • Cardellini M, Perego L. D'Adamo M, Marini MA, Procopio C, Hribal ML., et al. C-174G polymorphism in the promoter of the interleukin-6 gene is associated with insulin resistance Diabetes Care 2005; 28: 2007-2012.
    • (2005) Care , vol.28 , pp. 2007-2012
    • Cardellini, M.1    Perego, L.2    D'Adamo, M.3    Marini, M.A.4    Procopio, C.5    Hribal, M.L.6
  • 7
    • 0034938412 scopus 로고    scopus 로고
    • Elevated interleukin-6 plasma levels are regulated by the promoter region polymorphism of the IL6 gene in primary Sjogren's syndrome and correlate with the clinical manifestations of the disease
    • Hulkkonen J, Pertovaara M, Antonen J, Pastemack A, Hurme M. Elevated interleukin-6 plasma levels are regulated by the promoter region polymorphism of the IL6 gene in primary Sjogren's syndrome and correlate with the clinical manifestations of the disease. Rheumatology 2001; 40: 656-661.
    • (2001) Rheumatology , vol.40 , pp. 656-661
    • Hulkkonen, J.1    Pertovaara, M.2    Antonen, J.3    Pastemack, A.4    Hurme, M.5
  • 8
    • 0037312898 scopus 로고    scopus 로고
    • The C-174G promotbr polymorphism of the IL-6 gene affects energy expenditure and insulin sensitivity
    • Kubaszek A, Pihlajamaki J, Punnonen K, Karhapaa P, Vauhkonen I, Laakso M. The C-174G promotbr polymorphism of the IL-6 gene affects energy expenditure and insulin sensitivity. Diabetes 2003; 52: 558-561.
    • (2003) Diabetes , vol.52 , pp. 558-561
    • Kubaszek, A.1    Pihlajamaki, J.2    Punnonen, K.3    Karhapaa, P.4    Vauhkonen, I.5    Laakso, M.6
  • 9
    • 0242500485 scopus 로고    scopus 로고
    • Interleukin-6-gene CIG 174 polymorphism in nonagenarian and octogenarian subjects in the BELFAST study. Reciprocal effects on IL-6, soluble IL-6 receptor and for IL-10 in serum and monocyte supernatants
    • Rea IM, Ross OA, Armstrong M, McNerlan S, Alexander DH, Curran MD, et al. Interleukin-6-gene CIG 174 polymorphism in nonagenarian and octogenarian subjects in the BELFAST study. Reciprocal effects on IL-6, soluble IL-6 receptor and for IL-10 in serum and monocyte supernatants. Mech Ageing Dev 2003; 124: 555-561.
    • (2003) Mech Ageing Dev , vol.124 , pp. 555-561
    • Rea, I.M.1    Ross, O.A.2    Armstrong, M.3    McNerlan, S.4    Alexander, D.H.5    Curran, M.D.6
  • 11
    • 0344269351 scopus 로고    scopus 로고
    • Increase of interleukin 6 and decrease of interleukin 2 production during the ageing process are influenced by the health status
    • Mysliwska J, Bryl E, Foerster J, Mysliwski A. Increase of interleukin 6 and decrease of interleukin 2 production during the ageing process are influenced by the health status. Mech Ageing Dev 1998; 100: 313-328.
    • (1998) Mech Ageing Dev , vol.100 , pp. 313-328
    • Mysliwska, J.1    Bryl, E.2    Foerster, J.3    Mysliwski, A.4
  • 12
    • 0034051068 scopus 로고    scopus 로고
    • Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty
    • Ershler WB, Keller ET. Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty. Annu Rev Med 2000; 51: 245-270.
    • (2000) Annu Rev Med , vol.51 , pp. 245-270
    • Ershler, W.B.1    Keller, E.T.2
  • 13
    • 0031895616 scopus 로고    scopus 로고
    • Lipoprotein(a) and lipoprotein profile in healthy centenarians: A reappraisal of vascular risk factors
    • Baggio G, Donazzari S, Monti D, Mari D, Martini S, Gabelli C, et al. Lipoprotein(a) and lipoprotein profile in healthy centenarians: a reappraisal of vascular risk factors. FASEB J 1998; 12: 433-437.
    • (1998) FASEB J , vol.12 , pp. 433-437
    • Baggio, G.1    Donazzari, S.2    Monti, D.3    Mari, D.4    Martini, S.5    Gabelli, C.6
  • 16
    • 0031455903 scopus 로고    scopus 로고
    • Lifetime smoking exposure affects the association of C-reactive protein with cardiovascular disease risk factors and subclinical disease in healthy elderly subjects
    • Tracy RP, Psaty BM, Macy E, Bovill EG, Cushman M, Comell ES, et al. Lifetime smoking exposure affects the association of C-reactive protein with cardiovascular disease risk factors and subclinical disease in healthy elderly subjects. Arterioscler Thromb Vasc Biol 1997; 17: 2167-2176.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 2167-2176
    • Tracy, R.P.1    Psaty, B.M.2    Macy, E.3    Bovill, E.G.4    Cushman, M.5    Comell, E.S.6
  • 18
    • 0035908632 scopus 로고    scopus 로고
    • C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus
    • Pradhan AD, Manson JE, Rifai N, Buring JE, Ridker PM. C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA 2001; 286: 327-334.
    • (2001) JAMA , vol.286 , pp. 327-334
    • Pradhan, A.D.1    Manson, J.E.2    Rifai, N.3    Buring, J.E.4    Ridker, P.M.5
  • 19
    • 0345700727 scopus 로고    scopus 로고
    • Inflammatory cytokines and the risk to develop type 2 diabetes: Results of the prospective population-based European Prospective Investigation into Cancer and Nutritiom (EPIC)-Potsdam Study
    • Spranger J, Kroke A, Mohlig M, Hoffmann K, Bergmann MM, Ristow M, et al. Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutritiom (EPIC)-Potsdam Study. Diabetes 2003; 52: 812-817.
    • (2003) Diabetes , vol.52 , pp. 812-817
    • Spranger, J.1    Kroke, A.2    Mohlig, M.3    Hoffmann, K.4    Bergmann, M.M.5    Ristow, M.6
  • 20
    • 33750877102 scopus 로고    scopus 로고
    • IL6 gene promoter polymorphisms and type 2 diabetes: Joint analysis of individual participants' data from 21 studies
    • Huth C, Heid IM, Vollmert C, Gieger C, Grallert H, Wolford JK, et al. IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants' data from 21 studies. Diabetes 2006; 55: 2915-2921.
    • (2006) Diabetes , vol.55 , pp. 2915-2921
    • Huth, C.1    Heid, I.M.2    Vollmert, C.3    Gieger, C.4    Grallert, H.5    Wolford, J.K.6
  • 21
    • 0142185104 scopus 로고    scopus 로고
    • Variants in the interleukin 6 receptor gene are associated with obesity in Pima Indians
    • Wolford JK, Colligan PB, Gruber JD, Bogardus C. Variants in the interleukin 6 receptor gene are associated with obesity in Pima Indians. Mol Genet Metab 2003; 80: 338-343.
    • (2003) Mol Genet Metab , vol.80 , pp. 338-343
    • Wolford, J.K.1    Colligan, P.B.2    Gruber, J.D.3    Bogardus, C.4
  • 22
    • 0037849948 scopus 로고    scopus 로고
    • The interleukin-6 (-174) G/C promoter polymorphism is associated with type-2 diabetes mellitus in Native Americans and Caucasians
    • Vozarova B, Fernandez-Real JM, Knowler WC, Gallart L, Hanson RL, Gruber JD, et al. The interleukin-6 (-174) G/C promoter polymorphism is associated with type-2 diabetes mellitus in Native Americans and Caucasians. Hum Genet 2003; 112: 409-413.
    • (2003) Hum Genet , vol.112 , pp. 409-413
    • Vozarova, B.1    Fernandez-Real, J.M.2    Knowler, W.C.3    Gallart, L.4    Hanson, R.L.5    Gruber, J.D.6
  • 24
    • 33747139333 scopus 로고    scopus 로고
    • IL-6 promoter polymorphisms and quantitative traits related to the metabolic syndrome in KORA S4
    • Grallert H, Huth C, Kolz M, Meisinger C, Herder C, Strassburger K, et al. IL-6 promoter polymorphisms and quantitative traits related to the metabolic syndrome in KORA S4. Exp Gerontol 2006; 41: 737-745.
    • (2006) Exp Gerontol , vol.41 , pp. 737-745
    • Grallert, H.1    Huth, C.2    Kolz, M.3    Meisinger, C.4    Herder, C.5    Strassburger, K.6
  • 25
    • 0035571399 scopus 로고    scopus 로고
    • Blood pressure and inflammation in apparently healthy men
    • Chae CU, Lee RT, Rifai N, Ridker PM. Blood pressure and inflammation in apparently healthy men. Hypertension 2001; 38: 399-403.
    • (2001) Hypertension , vol.38 , pp. 399-403
    • Chae, C.U.1    Lee, R.T.2    Rifai, N.3    Ridker, P.M.4
  • 26
    • 0036632169 scopus 로고    scopus 로고
    • Peripheral mechanisms involved with catabolism
    • Langhans W. Peripheral mechanisms involved with catabolism. Curr Opin Clin Nutr Metab Care 2002; 5: 419-426.
    • (2002) Curr Opin Clin Nutr Metab Care , vol.5 , pp. 419-426
    • Langhans, W.1
  • 27
    • 0031762908 scopus 로고    scopus 로고
    • Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: Depot difference and regulation by glucocorticoid
    • Fried SK, Bunkin DA, Greenberg AS. Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid. J Clin Endocrinol Metab 1998; 83: 847-850.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 847-850
    • Fried, S.K.1    Bunkin, D.A.2    Greenberg, A.S.3
  • 30
    • 0026520358 scopus 로고
    • Insulin is a prominent modulator of the cytokine-stimulated expression of acute-phase plasma protein genes
    • Campos SP, Baumann H. Insulin is a prominent modulator of the cytokine-stimulated expression of acute-phase plasma protein genes. Mol Cell Biol 1992; 12: 1789-1797.
    • (1992) Mol Cell Biol , vol.12 , pp. 1789-1797
    • Campos, S.P.1    Baumann, H.2
  • 31
    • 0028815235 scopus 로고
    • Insulin and counterregulatory hormones influence acute-phase protein production in human hepatocytes
    • O'Riordain MG, Ross JA, Fearon KC, Maingay J, Farouk M, Garden OJ, et al. Insulin and counterregulatory hormones influence acute-phase protein production in human hepatocytes. Am J Physiol 1995; 269: E323-E330.
    • (1995) Am J Physiol , vol.269
    • O'Riordain, M.G.1    Ross, J.A.2    Fearon, K.C.3    Maingay, J.4    Farouk, M.5    Garden, O.J.6
  • 32
    • 0037631831 scopus 로고    scopus 로고
    • Insulin resistance and chronic cardiovascular inflammatory syndrome
    • Fernandez-Real JM, Ricart W. Insulin resistance and chronic cardiovascular inflammatory syndrome. Endocr Rev 2003; 24: 278-301.
    • (2003) Endocr Rev , vol.24 , pp. 278-301
    • Fernandez-Real, J.M.1    Ricart, W.2
  • 33
    • 0242580711 scopus 로고    scopus 로고
    • Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects
    • Rotter V, Nagaev I, Smith U. Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects. J Biol Chem 2003; 278: 45777-45784.
    • (2003) J Biol Chem , vol.278 , pp. 45777-45784
    • Rotter, V.1    Nagaev, I.2    Smith, U.3
  • 34
    • 0037853260 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes
    • Senn JJ, Klover PJ, Nowak IA, Zimmers TA, Koniaris LG, Furlanetto RW, et al. Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes. J Biol Chem 2003; 278: 13740-13746.
    • (2003) J Biol Chem , vol.278 , pp. 13740-13746
    • Senn, J.J.1    Klover, P.J.2    Nowak, I.A.3    Zimmers, T.A.4    Koniaris, L.G.5    Furlanetto, R.W.6
  • 35
    • 20244369579 scopus 로고    scopus 로고
    • Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes
    • Hamid YH, Rose CS, Urhammer SA, Glumer C, Nolsoe R, Kristiansen OP. et al. Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes. Diabetologia 2005;, 48: 251-260.
    • (2005) Diabetologia , vol.48 , pp. 251-260
    • Hamid, Y.H.1    Rose, C.S.2    Urhammer, S.A.3    Glumer, C.4    Nolsoe, R.5    Kristiansen, O.P.6
  • 37
    • 0037241338 scopus 로고    scopus 로고
    • Two promoter polymorphisms regulating interleukin-6 gene expression are associated with circulating levels of C-reactive protein and markers of bone resorption in postmenopausal women
    • Ferrari SL, Ahn-Luong L, Garnero P, Humphries SE, Greenspan SL. Two promoter polymorphisms regulating interleukin-6 gene expression are associated with circulating levels of C-reactive protein and markers of bone resorption in postmenopausal women. J Clin Endocrinol Metab 2003; 88: 255-259.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 255-259
    • Ferrari, S.L.1    Ahn-Luong, L.2    Garnero, P.3    Humphries, S.E.4    Greenspan, S.L.5
  • 38
    • 0032707321 scopus 로고    scopus 로고
    • Impaired production of proinflammatory cytokines in response to lipopolysaccharide (LPS) stimulation in elderly humans
    • Bruunsgaard H, Pedersen AN, Schroll M, Skinhoj P, Pedersen BK. Impaired production of proinflammatory cytokines in response to lipopolysaccharide (LPS) stimulation in elderly humans. Clin Exp Immunol 1999; 118: 235-241.
    • (1999) Clin Exp Immunol , vol.118 , pp. 235-241
    • Bruunsgaard, H.1    Pedersen, A.N.2    Schroll, M.3    Skinhoj, P.4    Pedersen, B.K.5
  • 39
    • 0034849867 scopus 로고    scopus 로고
    • A gender-dependent genetic predisposition to produce high levels of IL-6 is detrimental for longevity
    • Bonafe M, Olivieri F, Cavallone L, Giovagnetti S, Mayegiani F, Cardelli M, et al. A gender-dependent genetic predisposition to produce high levels of IL-6 is detrimental for longevity. Eur J Immunol 2001; 31: 2357-2361.
    • (2001) Eur J Immunol , vol.31 , pp. 2357-2361
    • Bonafe, M.1    Olivieri, F.2    Cavallone, L.3    Giovagnetti, S.4    Mayegiani, F.5    Cardelli, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.