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Volumn 100, Issue 3, 1998, Pages 313-328

Increase of interleukin 6 and decrease of interleukin 2 production during the ageing process are influenced by the health status

Author keywords

Ageing; Health status; IL2; IL6

Indexed keywords

CYTOKINE; INTERLEUKIN 2; INTERLEUKIN 6; MESSENGER RNA;

EID: 0344269351     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0047-6374(97)00154-1     Document Type: Article
Times cited : (91)

References (46)
  • 1
    • 0030021055 scopus 로고    scopus 로고
    • The biological effects of interleukin 6
    • Barton B.E. The biological effects of interleukin 6. Med. Res. Rev. 16:1996;87-109.
    • (1996) Med. Res. Rev. , vol.16 , pp. 87-109
    • Barton, B.E.1
  • 2
    • 0028835485 scopus 로고
    • Increased production of Tumor Necrosis Factor and Interleukin-6 by arterial wall of aged rats
    • Belmin J., Bernard C., Corman B., Merval R., esposito B., Tedgui A. Increased production of Tumor Necrosis Factor and Interleukin-6 by arterial wall of aged rats. Am. J. Physiol. 268:1995;H2288-H2293.
    • (1995) Am. J. Physiol. , vol.268
    • Belmin, J.1    Bernard, C.2    Corman, B.3    Merval, R.4    Esposito, B.5    Tedgui, A.6
  • 4
    • 0031062412 scopus 로고    scopus 로고
    • Nutritional status of centenarians assassed by activity and anthropometric, hematological and biochemical characteristics
    • Chan Y.C., Suzuki M., Yamamoto S. Nutritional status of centenarians assassed by activity and anthropometric, hematological and biochemical characteristics. J. Nutr. Sci. Vitaminol. 43:1997;73-81.
    • (1997) J. Nutr. Sci. Vitaminol. , vol.43 , pp. 73-81
    • Chan, Y.C.1    Suzuki, M.2    Yamamoto, S.3
  • 5
    • 0024435582 scopus 로고
    • Interleukin-2, Interleukin-2 receptor and interferon γ synthesis and mRNA expression in PMA and A23187 stimulated T cells from elderly humans
    • Chopra R.K., Holbrook N.J., Powers D.C., McCoy M.T., Adlerand W.H., Nagel J.E. Interleukin-2, Interleukin-2 receptor and interferon γ synthesis and mRNA expression in PMA and A23187 stimulated T cells from elderly humans. Clin. Immunol. Immunpathol. 53:1989;297-308.
    • (1989) Clin. Immunol. Immunpathol. , vol.53 , pp. 297-308
    • Chopra, R.K.1    Holbrook, N.J.2    Powers, D.C.3    McCoy, M.T.4    Adlerand, W.H.5    Nagel, J.E.6
  • 6
    • 0026750568 scopus 로고
    • Synergism of interleukin 6 and 1 alpha-25 dihydroxyvitamin D3 in induction of myeloid differentiation of human leukemic cell lines
    • Duits A.J., Dimjati W., Van de Winkel J.G., Capel P.J. Synergism of interleukin 6 and 1 alpha-25 dihydroxyvitamin D3 in induction of myeloid differentiation of human leukemic cell lines. J. Leukoc. Biol. 51:1992;237-243.
    • (1992) J. Leukoc. Biol. , vol.51 , pp. 237-243
    • Duits, A.J.1    Dimjati, W.2    Van De Winkel, J.G.3    Capel, P.J.4
  • 7
    • 0027371237 scopus 로고
    • Aging and lymphokine production by T cell subsets
    • Ernst D.N., Weigle W.O., Hobbs M.V. Aging and lymphokine production by T cell subsets. Stem Cells. 11:1993;487-498.
    • (1993) Stem Cells , vol.11 , pp. 487-498
    • Ernst, D.N.1    Weigle, W.O.2    Hobbs, M.V.3
  • 10
    • 0023181147 scopus 로고
    • Recombinant interferons or interleukin-2 increase cytotoxicity by human monocytes and NK cells
    • Frey J.R., Kamber M., Peck R. Recombinant interferons or interleukin-2 increase cytotoxicity by human monocytes and NK cells. Lymphokine Res. 6:1987;215-227.
    • (1987) Lymphokine Res. , vol.6 , pp. 215-227
    • Frey, J.R.1    Kamber, M.2    Peck, R.3
  • 11
    • 0025999752 scopus 로고
    • Interleukin 6 is constitutively produced by human CTL clones and is required to maintain their cytolytic function
    • Galandrini R., Cernetti C., Albi N., Dembech C., Terenzi A., Grignari F., Verlardi A. Interleukin 6 is constitutively produced by human CTL clones and is required to maintain their cytolytic function. Cell. Immunol. 138:1991;11-23.
    • (1991) Cell. Immunol. , vol.138 , pp. 11-23
    • Galandrini, R.1    Cernetti, C.2    Albi, N.3    Dembech, C.4    Terenzi, A.5    Grignari, F.6    Verlardi, A.7
  • 12
    • 0028922552 scopus 로고
    • Influence of age on human marrow
    • Glowacki J. Influence of age on human marrow. Calcif. Tissue Int. 56(Suppl.1):1995;S50-S51.
    • (1995) Calcif. Tissue Int. , vol.56 , Issue.SUPPL.1
    • Glowacki, J.1
  • 13
  • 14
    • 0029103416 scopus 로고
    • Interleukin-6 autoantibodies possible biological and clinical significance
    • Hansen M.B., Svenson M., Diamant M., Abell K., Bendtzen K. Interleukin-6 autoantibodies possible biological and clinical significance. Leukemia. 9:1995;1113-1115.
    • (1995) Leukemia , vol.9 , pp. 1113-1115
    • Hansen, M.B.1    Svenson, M.2    Diamant, M.3    Abell, K.4    Bendtzen, K.5
  • 15
    • 0023790982 scopus 로고
    • Age-related changes of expression of IL2-receptor subunits and kinetics of IL2 internalisation in T cells after mitogenic stimulation
    • Hara H., Tanaka T., Negoro S., Deguchi Y., Saiki O., Kishimoto S. Age-related changes of expression of IL2-receptor subunits and kinetics of IL2 internalisation in T cells after mitogenic stimulation. Mech. Ageing Dev. 45:1988;167-175.
    • (1988) Mech. Ageing Dev. , vol.45 , pp. 167-175
    • Hara, H.1    Tanaka, T.2    Negoro, S.3    Deguchi, Y.4    Saiki, O.5    Kishimoto, S.6
  • 17
    • 0021284678 scopus 로고
    • Ageing and immune response: A unifying hypothesis
    • Horan M.A., Fox R.A. Ageing and immune response: a unifying hypothesis. Mech. Ageing Dev. 26:1984;165-181.
    • (1984) Mech. Ageing Dev. , vol.26 , pp. 165-181
    • Horan, M.A.1    Fox, R.A.2
  • 19
    • 0025220865 scopus 로고
    • Accessory cell-derived helper signals in human T-cell activation with phytohemagglutinin, induction of interleukin 2, responsiveness by interleukin 6 and production of interleukin 2 by interleukin 1
    • Kuhweide R., Van Damme J., Lorre K., Baroja M.L., Tsudon M., L Ceuppens J. Accessory cell-derived helper signals in human T-cell activation with phytohemagglutinin, induction of interleukin 2, responsiveness by interleukin 6 and production of interleukin 2 by interleukin 1. Cytokine. 2:1990;45-54.
    • (1990) Cytokine , vol.2 , pp. 45-54
    • Kuhweide, R.1    Van Damme, J.2    Lorre, K.3    Baroja, M.L.4    Tsudon, M.5    L. Ceuppens, J.6
  • 20
    • 0025772901 scopus 로고
    • Increased spontaneous secretion of IL6 from B cells of patients with chronic lymphatic leukemia (B-CLL) and autoimmunity
    • Lahat N., Aghai E., Maronn B. Increased spontaneous secretion of IL6 from B cells of patients with chronic lymphatic leukemia (B-CLL) and autoimmunity. Clin. Exp. Immunol. 85:1991;302-306.
    • (1991) Clin. Exp. Immunol. , vol.85 , pp. 302-306
    • Lahat, N.1    Aghai, E.2    Maronn, B.3
  • 24
    • 0024316782 scopus 로고
    • Contribution of IL-6 to the antiproliferative effect of IL-1 and tumor necrosis Factor on tumor cell lines
    • Morinaga Y., Suzuki H., Takatsuki F., Akiyama Y., Taniyama T., Matsushima K., Onozaki K. Contribution of IL-6 to the antiproliferative effect of IL-1 and tumor necrosis Factor on tumor cell lines. J. Immunol. 143:1989;3538-3542.
    • (1989) J. Immunol. , vol.143 , pp. 3538-3542
    • Morinaga, Y.1    Suzuki, H.2    Takatsuki, F.3    Akiyama, Y.4    Taniyama, T.5    Matsushima, K.6    Onozaki, K.7
  • 25
    • 0025601628 scopus 로고
    • Cooperative interaction of nuclear factor kappa B and cis-regulator enhancer binding protein-like factor binding elements in activity the interleukin 8 gene by proinflammatory cytokines
    • Mukaida N., Mahe Y., Matsushima K. Cooperative interaction of nuclear factor kappa B and cis-regulator enhancer binding protein-like factor binding elements in activity the interleukin 8 gene by proinflammatory cytokines. J. Biol. Chem. 265:1990;2128-2133.
    • (1990) J. Biol. Chem. , vol.265 , pp. 2128-2133
    • Mukaida, N.1    Mahe, Y.2    Matsushima, K.3
  • 26
    • 0345130874 scopus 로고    scopus 로고
    • Overactivity of TNFα but not IL6 is associated with low NK cytotoxic activity in the elderly
    • Myśliwska J., Bryl E., Zorena K., Foerster J., Myśliwski A. Overactivity of TNFα but not IL6 is associated with low NK cytotoxic activity in the elderly. Gerontology. 43:1997;158-167.
    • (1997) Gerontology , vol.43 , pp. 158-167
    • Myśliwska, J.1    Bryl, E.2    Zorena, K.3    Foerster, J.4    Myśliwski, A.5
  • 27
    • 0026501412 scopus 로고
    • Macrophage differentiation-specific expression of NF-IL6, a transcription factor for IL6
    • Natsuka S., Akira S., Nishio Y., Hashimoto S., Sugita T., Isshiki H., Kishimoto T. Macrophage differentiation-specific expression of NF-IL6, a transcription factor for IL6. Blood. 79:1992;460-466.
    • (1992) Blood , vol.79 , pp. 460-466
    • Natsuka, S.1    Akira, S.2    Nishio, Y.3    Hashimoto, S.4    Sugita, T.5    Isshiki, H.6    Kishimoto, T.7
  • 28
    • 0016836760 scopus 로고
    • Immunological pattern in humans over 95 years of age
    • Radl J., Sepers J.M., Skvaril F. Immunological pattern in humans over 95 years of age. Clin. Exp. Immunol. 22:1975;84-90.
    • (1975) Clin. Exp. Immunol. , vol.22 , pp. 84-90
    • Radl, J.1    Sepers, J.M.2    Skvaril, F.3
  • 29
    • 0029925555 scopus 로고    scopus 로고
    • Changes in lymphocyte subsets, Interleukin 2, and suluble Interleukin 2 receptor in old and very old age
    • Rea I.M., Stewart M., Campbell P., Alexander H.D., Crockard A.D., Morris T.C.M. Changes in lymphocyte subsets, Interleukin 2, and suluble Interleukin 2 receptor in old and very old age. Gerontology. 42:1996;69-78.
    • (1996) Gerontology , vol.42 , pp. 69-78
    • Rea, I.M.1    Stewart, M.2    Campbell, P.3    Alexander, H.D.4    Crockard, A.D.5    Morris, T.C.M.6
  • 31
    • 0023638874 scopus 로고
    • Immune response of elderly adults to pneumococcus, variation by age, sex, and functional impairment
    • Roghmann K.J., Tabloski P.A., Bentley D.W., Schiffman G. Immune response of elderly adults to pneumococcus, variation by age, sex, and functional impairment. J. Gerontol. 3:1987;265-270.
    • (1987) J. Gerontol. , vol.3 , pp. 265-270
    • Roghmann, K.J.1    Tabloski, P.A.2    Bentley, D.W.3    Schiffman, G.4
  • 32
    • 0030596136 scopus 로고    scopus 로고
    • Interleukin-6 and interleukin-8 protein and gene expression in human arterial atherosclerotic wall
    • Rus H.G., Vlaicu R., Niculescu F. Interleukin-6 and interleukin-8 protein and gene expression in human arterial atherosclerotic wall. Atherosclerosis. 127:1996;263-271.
    • (1996) Atherosclerosis , vol.127 , pp. 263-271
    • Rus, H.G.1    Vlaicu, R.2    Niculescu, F.3
  • 33
    • 0025124491 scopus 로고
    • Secretion of interleukin 6 (IL6) by human monocytes stimulated by muramyl dipeptide and tumor necrosis factor alpha
    • Sanceau J., Falcoff R., Beranger F., Carter D.B., Wietzerbin J. Secretion of interleukin 6 (IL6) by human monocytes stimulated by muramyl dipeptide and tumor necrosis factor alpha. Immunology. 69:1990;52-56.
    • (1990) Immunology , vol.69 , pp. 52-56
    • Sanceau, J.1    Falcoff, R.2    Beranger, F.3    Carter, D.B.4    Wietzerbin, J.5
  • 34
    • 0024357546 scopus 로고
    • Endotoxin, tumor necrosis factor α and interleukin 1 induce interleukin 6 production in vivo
    • Shalaby M.R., Waage A., Aarden L., Espevik T. Endotoxin, tumor necrosis factor α and interleukin 1 induce interleukin 6 production in vivo. Clin. Immunol. Immunopathol. 53:1989;488-498.
    • (1989) Clin. Immunol. Immunopathol. , vol.53 , pp. 488-498
    • Shalaby, M.R.1    Waage, A.2    Aarden, L.3    Espevik, T.4
  • 35
    • 0026085022 scopus 로고
    • Comparison of the effect of IL2 and IL6 on the lytic activity of purified human peripheral blood large granular lymphocytes
    • Smyth J.M., Ortaldo J.R. Comparison of the effect of IL2 and IL6 on the lytic activity of purified human peripheral blood large granular lymphocytes. J. Immunol. 146:1991;1380-1384.
    • (1991) J. Immunol. , vol.146 , pp. 1380-1384
    • Smyth, J.M.1    Ortaldo, J.R.2
  • 38
    • 0027787510 scopus 로고
    • The influence of recombinant interleukin-6 on blood and immune parameters in middle-aged and old rhesus monkeys
    • Sun W.H., Binkley N., Bidwell D.W., Ershler W.B. The influence of recombinant interleukin-6 on blood and immune parameters in middle-aged and old rhesus monkeys. Lymphokine Cytokine Res. 12:1993;449-455.
    • (1993) Lymphokine Cytokine Res. , vol.12 , pp. 449-455
    • Sun, W.H.1    Binkley, N.2    Bidwell, D.W.3    Ershler, W.B.4
  • 39
    • 0030890718 scopus 로고    scopus 로고
    • Gp130 and the interleukin-6 family of cytokines
    • Taga T., Kishimoto T. Gp130 and the interleukin-6 family of cytokines. Annu. Rev. Immunol. 15:1997;797-819.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 797-819
    • Taga, T.1    Kishimoto, T.2
  • 40
    • 0023732978 scopus 로고
    • Human recombinant IL6/b cell stimulator factor 2 augments murine antigen-specific antibody responses in vitro and in vivo
    • Takasuki F., Okano A., Suzuki C., Chiela R., Takahara Y., Hirano T., Kishimoto T., Hamuro J., Akiyama Y. Human recombinant IL6/b cell stimulator factor 2 augments murine antigen-specific antibody responses in vitro and in vivo. J. Immunol. 141:1988;3072-3077.
    • (1988) J. Immunol. , vol.141 , pp. 3072-3077
    • Takasuki, F.1    Okano, A.2    Suzuki, C.3    Chiela, R.4    Takahara, Y.5    Hirano, T.6    Kishimoto, T.7    Hamuro, J.8    Akiyama, Y.9
  • 41
    • 0029900649 scopus 로고    scopus 로고
    • Evidence for lowered induction of nuclear factor kappa B in activated human T lymphocytes during aging
    • Trebilkock A., Ponnappan U.U. Evidence for lowered induction of nuclear factor kappa B in activated human T lymphocytes during aging. Gerontology. 42:1996;137-146.
    • (1996) Gerontology , vol.42 , pp. 137-146
    • Trebilkock, A.1    Ponnappan, U.U.2
  • 42
    • 0026497223 scopus 로고
    • Increase of plasma IL-6 concentration with age in healthy subjects
    • Wei J., Xu H., Davies J.L., Hemmings G.P. Increase of plasma IL-6 concentration with age in healthy subjects. Life Sci. 51:1993;1953.
    • (1993) Life Sci. , vol.51 , pp. 1953
    • Wei, J.1    Xu, H.2    Davies, J.L.3    Hemmings, G.P.4
  • 43
    • 0029935914 scopus 로고    scopus 로고
    • Age-related decreases in IL-2 production by human T cells are associated with impaired activation of nuclear transcriptional factors AP-1 and NF-AT
    • Whisler R.L., Beiqing L., Chen M. Age-related decreases in IL-2 production by human T cells are associated with impaired activation of nuclear transcriptional factors AP-1 and NF-AT. Cell. Immunol. 169:1996;185-195.
    • (1996) Cell. Immunol. , vol.169 , pp. 185-195
    • Whisler, R.L.1    Beiqing, L.2    Chen, M.3
  • 46
    • 0026318122 scopus 로고
    • Cancer in the aged
    • Yancik R., Ries L.G. Cancer in the aged. Cancer. 68 (suppl):1991;2502-2510.
    • (1991) Cancer , vol.68 , pp. 2502-2510
    • Yancik, R.1    Ries, L.G.2


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