Changes in HLA-DR expression, cytokine production and coagulation following endotoxin infusion in healthy human volunteers

International Immunopharmacology

Volumn 8, Issue 5, 2008, Pages 701-707

  Mant, Timothy G K ^a   Borozdenkova, Svetlana ^a   Bradford, Daniel B A ^a   Allen, Elizabeth ^a   Amin, Dipti M ^a   Toothaker, Roger D ^b   Collins, Robert W M ^c   Hargreaves, Roseanna E G ^c   Jurcevic, Stipo ^c  

^a Guy's Drug Research Unit Ltd   (United Kingdom)

^b Akros Pharma Inc   (United States)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Coagulation; Cytokines; Endotoxin; HLA DR expression

Indexed keywords

CYTOKINE; ENDOTOXIN; GRANULOCYTE COLONY STIMULATING FACTOR; HLA DR ANTIGEN; INTERLEUKIN 1 RECEPTOR ACCESSORY PROTEIN; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR;

ANTIGEN EXPRESSION; ARTICLE; BLOOD CLOTTING; BODY WEIGHT; CONCENTRATION (PARAMETERS); CYTOKINE PRODUCTION; FIBRINOLYSIS; HUMAN; HUMAN EXPERIMENT; INFUSION; LEUKOCYTE; MALE; MONOCYTE; NORMAL HUMAN; PRIORITY JOURNAL;

ANTITHROMBINS; BLOOD COAGULATION; C-REACTIVE PROTEIN; CYTOKINES; ELECTROCARDIOGRAPHY; ENDOTOXINS; FIBRINOLYSIS; GRANULOCYTE COLONY-STIMULATING FACTOR; HLA-DR ANTIGENS; HUMANS; LEUKOCYTE COUNT; LIPOPOLYSACCHARIDES; LIVER FUNCTION TESTS; PARTIAL THROMBOPLASTIN TIME;

EID: 41149139282     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2008.01.014     Document Type: Article

References (51)

1. Beutler B., and Rietschel E.T. Nat Rev Immunol 3 (2003) 169-176
2. Beutler B. Mol Immunol 40 (2004) 845-859
3. Rietschel E.T., Kirikae T., Schade F.U., Mamat U., Schmidt G., Loppnow H., et al. FASEB J 8 (1994) 217-225
4. Raetz C.R., Ulevitch R.J., Wright S.D., Sibley C.H., Ding A., and Nathan C.F. FASEB J 5 (1991) 2652-2660
5. Jiang Z., Georgel P., Du X., Shamel L., Sovath S., Mudd S., et al. Nat Immunol 6 (2005) 565-570
6. Beutler B., Jiang Z., Georgel P., Crozat K., Croker B., Rutschmann S., et al. Annu Rev Immunol 24 (2006) 353-389
7. Elin R.J., Wolff S.M., McAdam K.P., Chedid L., Audibert F., Bernard C., et al. J Infect Dis 144 (1981) 329-336
8. Michie H.R., Manogue K.R., Spriggs D.R., Revhaug A., O'Dwyer S., Dinarello C.A., et al. N Engl J Med 318 (1988) 1481-1486
9. Suffredini A.F., Fromm R.E., Parker M.M., Brenner M., Kovacs J.A., Wesley R.A., et al. N Engl J Med 321 (1989) 280-287
10. Martich G.D., Danner R.L., Ceska M., and Suffredini A.F. J Exp Med 173 (1991) 1021-1024
11. van Deventer S.J., Buller H.R., ten Cate J.W., Aarden L.A., Hack C.E., and Sturk A. Blood 76 (1990) 2520-2526
12. Morrison D.C., and Kline L.F. J Immunol 118 (1977) 362-368
13. Leitner J.M., Firbas C., Mayr F.B., Reiter R.A., Steinlechner B., and Jilma B. Clin Pharmacol Ther 79 (2006) 23-34
14. Santos A.A., and Wilmore D.W. Shock 6 Suppl 1 (1996) S50-S56
15. Hoebe K., Janssen E., and Beutler B. Nat Immunol 5 (2004) 971-974
16. Dinarello C.A. Chest 118 (2000) 503-508
17. Suter P.M., Suter S., Girardin E., Roux-Lombard P., Grau G.E., and Dayer J.M. Am Rev Respir Dis 145 (1992) 1016-1022
18. Wolk K., Kunz S., Crompton N.E., Volk H.D., and Sabat R. J Biol Chem 278 (2003) 18030-18036
19. Ditschkowski M., Kreuzfelder E., Majetschak M., Obertacke U., Schade U.F., and Grosse-Wilde H. Eur J Surg 165 (1999) 1129-1133
20. Hershman M.J., Cheadle W.G., Wellhausen S.R., Davidson P.F., and Polk Jr. H.C. Br J Surg 77 (1990) 204-207
21. Docke W.D., Randow F., Syrbe U., Krausch D., Asadullah K., Reinke P., et al. Nat Med 3 (1997) 678-681
22. van den Berk J.M., Oldenburger R.H., van den Berg A.P., Klompmaker I.J., Mesander G., van Son W.J., et al. Transplantation 63 (1997) 1846-1848
23. Muller Kobold A.C., Tulleken J.E., Zijlstra J.G., Sluiter W., Hermans J., Kallenberg C.G., and Tervaert J.W. Intensive Care Med 26 (2000) 883-892
24. Talwar S., Munson P.J., Barb J., Fiuza C., Cintron A.P., Logun C., et al. Physiol Genomics 25 (2006) 203-215
25. Suffredini A.F., Reda D., Banks S.M., Tropea M., Agosti J.M., and Miller R. J Immunol 155 (1995) 5038-5045
26. Van Zee K.J., Coyle S.M., Calvano S.E., Oldenburg H.S., Stiles D.M., Pribble J., et al. J Immunol 154 (1995) 1499-1507
27. Pajkrt D., Camoglio L., Tiel-van Buul M.C., de Bruin K., Cutler D.L., Affrime M.B., et al. J Immunol 158 (1997) 3971-3977
28. Bunnell E., Lynn M., Habet K., Neumann A., Perdomo C.A., Friedhoff L.T., et al. Crit Care Med 28 (2000) 2713-2720
29. Branger J., van den Blink B., Weijer S., Madwed J., Bos C.L., Gupta A., et al. J Immunol 168 (2002) 4070-4077
30. Kumar A., Zanotti S., Bunnell G., Habet K., Anel R., Neumann A., et al. Crit Care Med 33 (2005) 331-340
31. Rast J.P., Smith L.C., Loza-Coll M., Hibino T., and Litman G.W. Science 314 (2006) 952-956
32. Prabhakar U., Conway T.M., Murdock P., Mooney J.L., Clark S., Hedge P., et al. DNA Cell Biol 24 (2005) 410-431
33. Preas II H.L., Reda D., Tropea M., Vandivier R.W., Banks S.M., Agosti J.M., et al. Blood 88 (1996) 2465-2472
34. van der Poll T., Coyle S.M., Levi M., Jansen P.M., Dentener M., Barbosa K., et al. Blood 89 (1997) 3727-3734
35. Lauw F.N., Pajkrt D., Hack C.E., Kurimoto M., van Deventer S.J., and van der Poll T. J Immunol 165 (2000) 2783-2789
36. Schinkel C., Sendtner R., Zimmer S., and Faist E. J Trauma 44 (1998) 743-748 discussion 748-9
37. Ditschkowski M., Kreuzfelder E., Rebmann V., Ferencik S., Majetschak M., Schmid E.N., et al. Ann Surg 229 (1999) 246-254
38. Haveman J.W., van den Berg A.P., Verhoeven E.L., Nijsten M.W., van den Dungen J.J., The H.T., et al. Crit Care 10 (2006) R119
39. Le Tulzo Y., Pangault C., Amiot L., Guilloux V., Tribut O., Arvieux C., et al. Am J Respir Crit Care Med 169 (2004) 1144-1151
40. Fijen J.W., Kobold A.C., de Boer P., Jones C.R., van der Werf T.S., Tervaert J.W., et al. Eur J Intern Med 11 (2000) 89-95
41. Pajkrt D., Manten A., van der Poll T., Tiel-van Buul M.M., Jansen J., Wouter ten Cate J., et al. Blood 90 (1997) 1415-1424
42. Marsik C., Mayr F., Cardona F., Schaller G., Wagner O.F., and Jilma B. J Clin Immunol 24 (2004) 62-65
43. Pollmacher T., Korth C., Mullington J., Schreiber W., Sauer J., Vedder H., et al. Blood 87 (1996) 900-905
44. Erikstrup C., Ullum H., and Pedersen B.K. Clin Exp Immunol 144 (2006) 94-100
45. Aderka D., Engelmann H., Maor Y., Brakebusch C., and Wallach D. J Exp Med 175 (1992) 323-329
46. Gabay C., Smith M.F., Eidlen D., and Arend W.P. J Clin Invest 99 (1997) 2930-2940
47. Volanakis J.E. Mol Immunol 38 (2001) 189-197
48. Bisoendial R.J., Kastelein J.J., Levels J.H., Zwaginga J.J., van den Bogaard B., Reitsma P.H., et al. Circ Res 96 (2005) 714-716
49. Weinhold B., Bader A., Poli V., and Ruther U. Biochem J 325 Pt 3 (1997) 617-621
50. Suffredini A.F., Hochstein H.D., and McMahon F.G. J Infect Dis 179 (1999) 1278-1282
51. Kemna E., Pickkers P., Nemeth E., van der Hoeven H., and Swinkels D. Blood 106 (2005) 1864-1866