Diffusion-limited reactions in G-protein activation: Unexpected consequences of antagonist and agonist competition

Journal of Theoretical Biology

Volumn 251, Issue 4, 2008, Pages 561-569

  Brinkerhoff, Christopher J ^a   Choi, Ji Sun ^a   Linderman, Jennifer J ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Desensitization; G protein coupled receptor; Model; Simulation

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHOTRANSFERASE;

ANTAGONISM; DIFFUSION; EXPERIMENTAL STUDY; MODEL; MONTE CARLO ANALYSIS; PROTEIN; REACTION KINETICS;

ARTICLE; DIFFUSION; DISSOCIATION; KINETICS; MONTE CARLO METHOD; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION;

ANIMALS; CELL MEMBRANE; COMPUTER SIMULATION; DIFFUSION; GTP-BINDING PROTEINS; HUMANS; MODELS, BIOLOGICAL; MONTE CARLO METHOD; PHOSPHORYLATION; PHOSPHOTRANSFERASES; PROTEIN BINDING; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION;

EID: 41049090774     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2008.01.002     Document Type: Article

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