Carbonic anhydrase inhibition. Insight into the characteristics of zonisamide, topiramate, and the sulfamide cognate of topiramate

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 23, Issue 2, 2008, Pages 271-276

  Shank, Richard P ^a   Smith Swintosky, Virginia L ^a   Maryanoff, Bruce E ^a  

^a Johnson and Johnson Pharmaceutical Research and Development   (United States)

Author keywords

Carbonic anhydrase; Inhibition; Preincubation; Sulfamide; Topiramate; Zonisamide

Indexed keywords

CARBON DIOXIDE; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; JNJ 17065984; SULFANILAMIDE DERIVATIVE; TOPIRAMATE; UNCLASSIFIED DRUG; ZONISAMIDE;

ARTICLE; DRUG MECHANISM; ENZYME INHIBITION; ENZYME KINETICS; HYDRATION; IC 50; PRIORITY JOURNAL;

CARBONIC ANHYDRASE I; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; ERYTHROCYTES; FRUCTOSE; HUMANS; ISOXAZOLES; SULFONAMIDES;

EID: 40949145238     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.1080/14756360701507001     Document Type: Article

References (24)

1. Wistrand, PJ. (2000) The carbonic anhydrases: New horizons, pp. 597-609. Birkhäuser Verlag, Basel
2. Scozzafava, A., Mastrolorenzo, A. and Supuran, CT (2004) Expert Opin Ther Pat, 14, pp. 667-702.
3. Maren, TH. (2000) The carbonic anhydrases: New horizons, pp. 425-436. Birkhäuser Verlag, Basel
4. Parkkila, S., Parkkila, A-K and Kivela, J. (2004) Carbonic anhydrase: Its inhibitors and activators, pp. 283-301. CRC Press, Boca Raton, FL
5. Rogawski, MA and Löscher, W. (2004) Nat Rev Neurosci, 5, pp. 553-564.
6. Matsumoto, K., Miyazaki, H., Fujii, T. and Hashimoto, M. (1989) Chem Pharm Bull, 37, pp. 1913-1915.
7. Masuda, Y. and Karasawa, T. (1993) Arzneim-Forsch, 43, pp. 416-418.
8. Masuda, Y., Noguchi, H. and Karasawa, T. (1994) Arzneim.-Forsch, 44, pp. 267-269.
9. Maryanoff, BE, Nortey, SO, Gardocki, JF, Shank, RP and Dodgson, SP (1987) J Med Chem, 30, pp. 880-887.
10. Shank, RP, Gardocki, JF, Vaught, JL, Davis, CB, Schupsky, JJ, Raffa, RB, Dodgson, SJ, Nortey, SO and Maryanoff, BE (1994) Epilepsia, 35, pp. 450-460.
11. Dodgson, SJ, Shank, RP and Maryanoff, BE (2000) Epilepsia, 41, pp. S35-S39.
12. Shank, RP, Doose, DR, Streeter, AJ and Bialer, M. (2005) Epilepsy Res, 63, pp. 103-112.
13. Maryanoff, BE, McComsey, DF, Costanzo, MJ, Hochman, C., Smith-Swintosky, V. and Shank, RP (2005) J Med Chem, 48, pp. 1941-1947.
14. Klinger, AL, McComsey, DF, Smith-Swintosky, V., Shank, RP and Maryanoff, BE (2006) J Med Chem, 49, pp. 3496-3500.
15. Shank, RP, McComsey, DF, Smith-Swintosky, VL and Maryanoff, BE (2006) Chem Biol Drug Design, 68, pp. 113-119.
16. Casini, A., Antel, J., Abbate, F., Scozzafava, A., David, S., Waldeck, H., Schäfer, S. and Supuran, CT (2003) Bioorg Med Chem Lett, 13, pp. 841-845.
17. Winum, J-Y, Temperini, C., Cheikh, KE, Innocenti, A., Vullo, D., Ciattini, S., Montero, J-L, Scozzafava, A. and Supuran, CT (2006) J Med Chem, 49, pp. 7024-7031.
18. De Simone, G., Fiore, A Di, Menchise, V., Pedone, C., Antel, J., Casini, A., Scozzafava, A., Wurlb, M. and Supuran, CT (2005) Bioorg Med Chem Lett, 15, pp. 2315-2320.
19. Thorslund, A. and Lindskog, S. (1967) Eur J Biochem, 3, pp. 117-123.
20. Pocker, Y. and Stone, JT (1967) Biochemistry, 6, pp. 668-678.
21. Cheng, Y. and Prusoff, WH (1973) Biochem Pharmacol, 22, pp. 3099-3108.
22. Matulis, D., Kranz, JK, Salemme, FR and Todd, MJ (2005) Biochemistry, 44, pp. 5258-5266.
23. Cammer, W., Fredman, T., Rose, AL and Norton, WT (1976) J Neurochem, 27, pp. 165-171.
24. Husic, HD, Hsieh, S. and Berrier, AL (1991) Biochim Biophys Acta, 1078, pp. 35-42.