Examination of two independent kinetic assays for determining the inhibition of carbonic anhydrases I and II: Structure-activity comparison of sulfamates and sulfamides

Chemical Biology and Drug Design

Volumn 68, Issue 2, 2006, Pages 113-119

  Shank, Richard P ^a   McComsey, David F ^a   Smith Swintosky, Virginia L ^a   Maryanoff, Bruce E ^a  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

4 nitrophenylacetate hydrolysis; Carbonic anhydrase; CO2 hydration; Sulfamate; Sulfamide; Sulfonamide

Indexed keywords

4 NITROPHENYLACETIC ACID; ACETAZOLAMIDE; CARBON DIOXIDE; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE INHIBITOR; FRUCTOSE; PHENYLACETIC ACID; SULFAMIC ACID; SULFAMIDE DERIVATIVE; UNCLASSIFIED DRUG; ZONISAMIDE;

ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENCY; DRUG SELECTIVITY; DRUG TARGETING; ENANTIOMER; ENZYME ASSAY; ENZYME INHIBITION; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; HYDRATION; INHIBITION KINETICS; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

CARBONIC ANHYDRASE I; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; KINETICS; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONIC ACIDS;

EID: 33749011965     PISSN: 17470277     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2006.00423.x     Document Type: Article

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