Transgenic tissue-type plasminogen activator expression improves host defense during Klebsiella pneumonia

Journal of Thrombosis and Haemostasis

Volumn 6, Issue 4, 2008, Pages 660-668

  Renckens, Rosemarijn ^a,b   Roelofs, J J T H ^c   Stegenga, M E ^a,b   Florquin, S ^c   Levi, M ^c   Carmeliet, P ^d   Van't Veer, C ^a,b   Van Der Poll, T ^a,b  

^a Center for Infection and Immunity Amsterdam CINIMA   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

^d UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Fibrinolysis; Host defense; Inflammation; Sepsis

Indexed keywords

ADENOVIRUS VECTOR; D DIMER; TISSUE PLASMINOGEN ACTIVATOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL GROWTH; BACTERIAL PNEUMONIA; DRUG MECHANISM; FEMALE; FIBRINOLYSIS; GENE EXPRESSION; GENE OVEREXPRESSION; GENE THERAPY; GENE TRANSFER; HOST RESISTANCE; INFECTION RESISTANCE; KLEBSIELLA PNEUMONIAE; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SEPSIS; TRANSGENE; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; ADMINISTRATION, INTRANASAL; ANIMALS; FEMALE; FIBRIN; FIBRIN FIBRINOGEN DEGRADATION PRODUCTS; FIBRINOLYSIS; GENETIC VECTORS; HUMANS; IMMUNITY, NATURAL; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; LUNG; MICE; MICE, INBRED C57BL; PNEUMONIA, BACTERIAL; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; SEPSIS; TISSUE PLASMINOGEN ACTIVATOR; TRANSGENES;

EID: 40949113136     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2008.02892.x     Document Type: Article

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