Effects of prednisolone on the systemic release of mediators of cell-mediated cytotoxicity during human endotoxemia

Shock

Volumn 29, Issue 4, 2008, Pages 458-461

  De Kruif, Martijn D ^a,d   Lemaire, Lucienne C ^b   Giebelen, Ida A ^a   Groot, Angelique P ^a   Pater, Jennie M ^a   Van Den Pangaart, Petra S ^a   Elliott, Peter J ^c,e   Van Der Poll, Tom ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c Department of Preclinical Development and Formulations   (United States)

^d ACADEMIC MEDICAL CENTER   (Netherlands)

^e GLAXOSMITHKLINE   (United States)

Author keywords

Chemokines; Corticosteroids; Endotoxin; Granzymes; LPS; Phospholipase; Volunteers

Indexed keywords

GRANZYME A; GRANZYME B; LIPOPOLYSACCHARIDE; PHOSPHOLIPASE A2; PREDNISOLONE;

ARTICLE; CELL MEDIATED CYTOTOXICITY; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; ENDOTOXEMIA; ENZYME RELEASE; ESCHERICHIA COLI; HUMAN; IN VIVO STUDY; MEDIATOR RELEASE;

ADMINISTRATION, ORAL; ADULT; CHEMOKINE CXCL10; CHEMOKINE CXCL9; CYTOTOXICITY, IMMUNOLOGIC; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTOXEMIA; GRANZYMES; HUMANS; INJECTIONS, INTRAVENOUS; KILLER CELLS, NATURAL; LIPOPOLYSACCHARIDES; MALE; PREDNISOLONE; T-LYMPHOCYTES; T-LYMPHOCYTES, CYTOTOXIC;

EID: 40949111066     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e3181598a6a     Document Type: Article

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