Abrogation of AIDS vaccine-induced cytotoxic T-lymphocyte efficacy in vivo due to a change in viral epitope flanking sequences

Microbes and Infection

Volumn 10, Issue 3, 2008, Pages 285-292

  Moriya, Chikaya ^a   Igarashi, Hiroko ^b   Takeda, Akiko ^a   Tsukamoto, Tetsuo ^a,b   Kawada, Miki ^a,b   Yamamoto, Hiroyuki ^a,b   Inoue, Makoto ^c   Iida, Akihiro ^c   Shu, Tsugumine ^c   Hasegawa, Mamoru ^c   Nagai, Yoshiyuki ^d   Matano, Tetsuro ^a,b,e  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c University of Tokyo   (Japan)

^d RIKEN YOKOHAMA INSTITUTE   (Japan)

^e NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

AIDS vaccine; Cytotoxic T lymphocyte; Escape; Simian immunodeficiency virus

Indexed keywords

AMINO ACID; DNA VACCINE; EPITOPE; GAG PROTEIN; GLUTAMIC ACID; HUMAN IMMUNODEFICIENCY VIRUS VACCINE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DRUG EFFICACY; HAPLOTYPE; IMMUNE RESPONSE; IN VIVO STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS REPLICATION;

ADMINISTRATION, INTRANASAL; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CELLS, CULTURED; EPITOPES, T-LYMPHOCYTE; GENE PRODUCTS, GAG; IMMUNIZATION, SECONDARY; INJECTIONS, INTRAMUSCULAR; LEUKOCYTES, MONONUCLEAR; MACACA MULATTA; MOLECULAR SEQUENCE DATA; SAIDS VACCINES; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; SPECIES SPECIFICITY; T-LYMPHOCYTES, CYTOTOXIC; VACCINATION; VACCINES, DNA; VIRUS REPLICATION;

MACACA; MACACA MULATTA; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 40949090132     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2007.12.002     Document Type: Article

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