Characteristics of genomic signatures derived using univariate methods and mechanistically anchored functional descriptors for predicting drug- and xenobiotic-induced nephrotoxicity

Toxicology Mechanisms and Methods

Volumn 18, Issue 2-3, 2008, Pages 267-276

  Shi, Weiwei ^a   Bugrim, Andrej ^a   Nikolsky, Yuri ^a   Nikolskya, Tatiana ^b   Brennan, Richard J ^a,c  

^a GeneGo bioinformatics software Inc   (United States)

^b VAVILOV INSTITUTE OF GENERAL GENETICS   (Russian Federation)

^c NONE   (United States)

Author keywords

Canonical Pathway Maps; Enrichment Analysis; Feature Selection; Functional Descriptors; Multivariate Analysis; Out of Bag Validation; Renal Tubular Toxicity; Signatures; Univariate Analysis

Indexed keywords

4 NONYLPHENOL; 4,4' ISOPROPYLIDENEDIPHENOL; ACARBOSE; ACETYLSALICYLIC ACID; AMPRENAVIR; CANDESARTAN; CARBOPLATIN; CELECOXIB; CISPLATIN; CLINDAMYCIN; CLOFIBRATE; CROMOGLYCATE DISODIUM; CYCLOSPORIN A; DAUNORUBICIN; DOXORUBICIN; GENTAMICIN; GLICLAZIDE; IDARUBICIN; INDINAVIR; KETOPROFEN; NETILMICIN; RIFABUTIN; RIFAPENTINE; ROXARSONE; TENIDAP; TOBRAMYCIN; UNINDEXED DRUG; VALACICLOVIR; VALPROIC ACID; XENOBIOTIC AGENT; ZOMEPIRAC;

ALGORITHM; ANIMAL EXPERIMENT; ARTICLE; DATA BASE; GENETIC ANALYSIS; GENOMICS; HOMEOSTASIS; KIDNEY DEVELOPMENT; KIDNEY TUBULE; KNOWLEDGE BASE; LINEAR SYSTEM; MOLECULAR PROBE; NEPHROTOXICITY; NONHUMAN; PREDICTION; PRIORITY JOURNAL; RISK ASSESSMENT; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; STATISTICS; TOXICOGENETICS; UNIVARIATE ANALYSIS;

EID: 40949089698     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.1080/15376510701857072     Document Type: Article

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