Insulin-like growth factor type-I receptor-dependent phosphorylation of extracellular signal-regulated kinase 1/2 but not Akt (protein kinase B) can be induced by picropodophyllin

Molecular Pharmacology

Volumn 73, Issue 3, 2008, Pages 930-939

  Vasilcanu, Radu ^a   Vasilcanu, Daiana ^a   Sehat, Bita ^a   Yin, Shucheng ^a,c   Girnita, Ada ^a   Axelson, Magnus ^b   Girnita, Leonard ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c ZHONGNAN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

LIGNAN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PICROPODOPHYLLIN; PROTEIN KINASE B; PROTEIN MDM2; SMALL INTERFERING RNA; SOMATOMEDIN C RECEPTOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER GRAFT; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; SIGNAL TRANSDUCTION; SURVIVAL RATE; TUMOR REGRESSION; UBIQUITINATION;

CELL SURVIVAL; ENZYME ACTIVATION; ENZYME INDUCTION; GLIOBLASTOMA; HUMANS; MELANOMA; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; PODOPHYLLOTOXIN; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, IGF TYPE 1; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSFECTION; TUMOR CELLS, CULTURED; UBIQUITINATION;

EID: 40849131149     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.107.040014     Document Type: Article

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