Regulation of expression of the steroidogenic acute regulatory protein (StAR) gene: A central role for steroidogenic factor 1

Steroids

Volumn 62, Issue 1, 1997, Pages 5-9

  Sugawara, Teruo ^a   Kiriakidou, Marianthi ^a   McAllister, Jan M ^b   Holt, John A ^a   Arakane, Futoshi ^a   Strauss III, Jerome F ^a,c  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c Ctr for Res on Repro and W H   (United States)

Author keywords

cAMP; StAR gene; steroidogenic factor 1

Indexed keywords

REGULATOR PROTEIN;

ADRENAL CORTEX CELL; CONFERENCE PAPER; GENE ACTIVATION; GENE EXPRESSION REGULATION; GRANULOSA CELL; HUMAN; STEROIDOGENESIS; TRANSCRIPTION REGULATION;

MURINAE;

EID: 0031022664     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-128X(96)00152-3     Document Type: Conference Paper

References (12)

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2. Rennert H, Chang YJ, Strauss III JF (1993). Intracellular cholesterol dynamics in steroidogenic cells: a contemporary view. In: Adashi EY, Leung PCK (eds), The Ovary, Raven Press, New York, pp. 147-164.
3. Stocco DM, Clark BJ (1996). Regulation of the acute production of steroids in steroidogenic cells. Endocr Rev 17:221-244.
4. Clark BJBJ, Wells J, King SR, Stocco DM (1994). The purification, cloning, and expression of a novel LH-induced mitochondrial protein in MA-10 mouse Leydig tumor cells: characterization of the steroidogenic acute regulatory protein (StAR) protein. J Biol Chem 269:28314-28322.
5. Sugawara T, Holt JA, Driscoll D, Strauss JF III, Lin D, Miller WL, Patterson D, Clancy KP, Hart IM, Clark BJ, Stocco DM (1995). Human steroidogenic acute regulatory protein: functional activity in COS-1 cells, tissue-specific expression, mapping of the gene to 8p11.2 and a pseudogene to chromosome 13. Proc Natl Acad Sci USA 92:4778-4782.
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7. Tee MK, Lin D, Sugawara T, Holt JA, Guigen Y, Buckingham B, Strauss III JF, Miller WL (1995). T-A transversion 11 bp from a splice acceptor site in the human gene for steroidogenic acute regulatory protein causes congenital lipoid adrenal hyperplasia. Hum Mol Genet 4:2299-2305.
8. Kiriakidou M, McAllister JM, Sugarwara T, Strauss III JF (1996). Expression of steroidogenic acute regulatory protein (StAR) in the human ovary. J Clin Endocrinol Metab 81:4122-4128.
9. Lala DS, Ikeda Y, Luo X, Baity LA, Meade JC, Parker KL (1995). A cell-specific nuclear receptor regulates the steroid hydroxylases. Steroids 14:10-14.
10. Morohashi K, Hatano O, Nomura M, Takayama K, Hara M, Yoshii H, Takakusu A, Omura T (1995). Function and distribution of a steroidogenic cell-specific transcription factor, Ad4BP. J Steroid Biochem Mol Biol 53:81-88.
11. Sugawara T, Holt JA, Kiriakidou M, Strauss III JF (1996). Steroidogenic factor 1-dependent promoter activity of the human steroidogenic acute regulatory protein (StAR) gene. Biochemistry 35:9052-9059.
12. Sugawara T, Lin D, Holt JA, Martin KO, Javitt NB, Miller WL, Strauss III JF (1995). Structure of the human steroidogenic acute regulatory protein (StAR) gene: StAR stimulates mitochondrial cholesterol 27-hydroxylase activity. Biochemistry 34:12506-12512.