Synthesis of new 1,3,8-trisubstituted purine-2,6-diones and 1,3,6-trisubstituted thiazolo[2,3-f]purine-2,4diones

Heterocycles

Volumn 74, Issue C, 2007, Pages 369-382

  Hayallah, Alaa M ^a,b   Famulok, Michael ^a  

^a UNIVERSITY OF BONN   (Germany)

^b Assiut University   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 40749157144     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/com-07-s(w)15     Document Type: Article

References (30)

1. Sadzuka Y., Sugiyama T., Suzuki H., Sawanishi H., and Miyamoto K. Toxicology Lett. 150 (2004) 341
2. Sadzuka Y., Egawa Y., Sawanishi H., Miyamoto K., and Sonobe T. Toxicology Lett. 135 (2002) 137
3. Taisei U., Tsuneyasu A., Jinsaku S., Masahisa A., and Jozi N. Chem. Pharm. Bull. 35 (1987) 4031
4. Da Settimo A., Da Settimo F., Marini A.M., Primofiore G., Salermo S., Viola G., Dalla Via L., and Magno S.M. Eur. J. Med. Chem. 33 (1998) 685
5. Arnold R., Beer D., Bhalay G., Baettig U., Collingwood S., Craig S., Devereux N., Dunstan A., Glen A., Gomez S., Harberthuer S., Howe T., Jells S., Moser H., Naef R., Nicklin P., Sandham D., Stringer R., Turner K., Waston S., and Zurini M. Bioorg. Med. Chem. Lett. 12 (2002) 2587
6. Raj S., and Dhala S. Appl. Microbiol. 13 (1965) 432
7. Basyouni W., Hosni H., and Helmy S. Egy. J. Chem. 42 (1999) 587
8. Persson C., Anderson K., and Kjellin G. Life Sci. 38 (1986) 1057
9. Feoktistov I., and Biaggioni I. Drug Dev. Res. 39 (1996) 333
10. Berk B., Akgün H., Erol K., Sirmagül B., Gao Z.-G., and Jacobson K.A. ll Farmaco 60 (2005) 974
11. Blythin D., Kaminski J., Domalski M., Spitler J., Solomon D., Corm D., Wong S., Verbiar L., Bober L., Chiu P., Watnick A., Siegel M., Hilbert J., and McPhail A. J. Med. Chem. 29 (1986) 1099
12. Foley L.H., Wang P., Dunten P., Ramsey G., Gublar M.L., and Wertheimer S.J. Bioorg. Med. Chem. Lett. 13 (2003) 3607
13. Hayallah A.M., Sandoval-Ramirez J., Reith U., Schobert U., Preiss B., Schumacher B., Daly J., and Müller C. J. Med. Chem. 45 (2002) 1500
14. Abo Salem O., Hayallah A.M., Bilkei-Gorzo A., Filipek B., Abdel Wahab M., Hamada F., Zimmer A., and Müller C. J. Pharamacol. Exp. Ther. 308 (2004) 358
15. Hayallah A.M. Pharmacia (2007) 54 in press
16. Dietz A., and Burgison R. J. Med. Chem. 9 (1966) 160
17. Yanovskaya L. Dokl. Akad. Nauk. SSSR 71 (1950) 693 (CA, 1950, 44, 8354)
18. Yanovskaya L., and Terentev A. Zhur. Obshch. Khim. 22 (1952) 1598 (CA, 1953, 47, 9258)
19. Machinkaya L., and Prodberezina A. Zhur. Obshch. Khim. 28 (1958) 1501 (CA, 1959, 53, 1184)
20. Lister L. fused pyrimidines. In: Brown D. (Ed). part 2, Purines (1971), Wiley-Interscience, New York 278-281
21. Uno H., Irie A., and Hino K. Chem. Pharm Bull. 21 (1973) 256
22. 8 but succeeded with 1,3,8-trisubstituted xanthines although the cyclised product needed tedious purification.
23. Lebreton S., Newcombe N., and Bradley M. Tetrahedron 59 (2003) 10213
24. Müller C., and Sandoval-Ramirez J. Synthesis (1995) 1295
25. Müller C.E. Tetrahedron Lett. 32 (1991) 6539
26. Janda K., Ashley J., Jones T., Mcleod D., Schoelder D., Weinhouse M., Lerner R., Gibbs R., Benkovic P., Hilhorst R., and Benkovic S. J. Am. Chem. Soc. 113 (1991) 291
27. Weyler S., Hayallah A., and Müller C. Tetrahedron 59 (2003) 47
28. Compound 30 was reported in reference 6 by different methods without reporting any data.
29. 13C-NMR of compound 32 in reference 6.
30. Papesh V., and Schroeder E. J. Org. Chem. 16 (1951) 1879