메뉴 건너뛰기




Volumn 31, Issue 1, 2008, Pages 34-42

CpG therapy is superior to BCG in an orthotopic bladder cancer model and generates CD4+ T-cell immunity

Author keywords

BCG; CpG ODNs; Experimental bladder cancer; MB49; Memory

Indexed keywords

BCG VACCINE; CPG OLIGODEOXYNUCLEOTIDE; CYTOKINE; MEDAC; ANTIBODY; CPG OLIGONUCLEOTIDE; CPG-OLIGONUCLEOTIDE; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; IMMUNOLOGICAL ADJUVANT; OLIGODEOXYRIBONUCLEOTIDE; UNCLASSIFIED DRUG;

EID: 40749103853     PISSN: 15249557     EISSN: None     Source Type: Journal    
DOI: 10.1097/CJI.0b013e3181587d29     Document Type: Article
Times cited : (42)

References (39)
  • 1
    • 0033562695 scopus 로고    scopus 로고
    • BCG immunotherapy of bladder cancer: 20 years on
    • Alexandroff AB, Jackson AM, O'Donnell MA, et al. BCG immunotherapy of bladder cancer: 20 years on. Lancet. 1999;353:1689-1694.
    • (1999) Lancet , vol.353 , pp. 1689-1694
    • Alexandroff, A.B.1    Jackson, A.M.2    O'Donnell, M.A.3
  • 2
    • 0034822163 scopus 로고    scopus 로고
    • Diagnosis and management of superficial bladder cancer
    • Amling CL. Diagnosis and management of superficial bladder cancer. Curr Probl Cancer. 2001;25:219-278.
    • (2001) Curr Probl Cancer , vol.25 , pp. 219-278
    • Amling, C.L.1
  • 4
    • 0026751765 scopus 로고
    • Changes of host cell infiltration into Meth A fibrosarcoma tumor during the course of regression induced by injections of a BCG nucleic acid fraction
    • Kuramoto E, Watanabe N, Iwata D, et al. Changes of host cell infiltration into Meth A fibrosarcoma tumor during the course of regression induced by injections of a BCG nucleic acid fraction. Int J Immunopharmacol. 1992;14:773-782.
    • (1992) Int J Immunopharmacol , vol.14 , pp. 773-782
    • Kuramoto, E.1    Watanabe, N.2    Iwata, D.3
  • 5
    • 0028931102 scopus 로고
    • CpG motifs in bacterial DNA trigger direct B-cell activation
    • Krieg AM, Yi AK, Matson S, et al. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature. 1995;374:546-549.
    • (1995) Nature , vol.374 , pp. 546-549
    • Krieg, A.M.1    Yi, A.K.2    Matson, S.3
  • 6
    • 0023472826 scopus 로고
    • CpG islands as gene markers in the vertebrate nucleus
    • Bird AP. CpG islands as gene markers in the vertebrate nucleus. Trends Genet. 1995;3:342-347.
    • (1995) Trends Genet , vol.3 , pp. 342-347
    • Bird, A.P.1
  • 7
    • 0035477969 scopus 로고    scopus 로고
    • Cutting edge: Role of Toll-like receptor 9 in CpG DNA-induced activation of human cells
    • Takeshita F, Leifer CA, Gursel I, et al. Cutting edge: role of Toll-like receptor 9 in CpG DNA-induced activation of human cells. J Immunol. 2001;167:3555-3558.
    • (2001) J Immunol , vol.167 , pp. 3555-3558
    • Takeshita, F.1    Leifer, C.A.2    Gursel, I.3
  • 8
    • 0034619794 scopus 로고    scopus 로고
    • A Toll-like receptor recognizes bacterial DNA
    • Hemmi H, Takeuchi O, Kawai T, et al. A Toll-like receptor recognizes bacterial DNA. Nature. 2000;408:740-745.
    • (2000) Nature , vol.408 , pp. 740-745
    • Hemmi, H.1    Takeuchi, O.2    Kawai, T.3
  • 9
    • 0038236749 scopus 로고    scopus 로고
    • Rational design of new CpG oligonucleotides that combine B cell activation with high IFN-alpha induction in plasmacytoid dendritic cells
    • Hartmann G, Battiany J, Poeck H, et al. Rational design of new CpG oligonucleotides that combine B cell activation with high IFN-alpha induction in plasmacytoid dendritic cells. Eur J Immunol. 2003;33:1633-1641.
    • (2003) Eur J Immunol , vol.33 , pp. 1633-1641
    • Hartmann, G.1    Battiany, J.2    Poeck, H.3
  • 10
    • 11344284095 scopus 로고    scopus 로고
    • CpG oligonucleotide therapy cures subcutaneous and orthotopic tumors and evokes protective immunity in murine bladder cancer
    • Ninalga C, Loskog A, Klevenfeldt M, et al. CpG oligonucleotide therapy cures subcutaneous and orthotopic tumors and evokes protective immunity in murine bladder cancer. J Immunother. 2005;28:20-27.
    • (2005) J Immunother , vol.28 , pp. 20-27
    • Ninalga, C.1    Loskog, A.2    Klevenfeldt, M.3
  • 11
    • 4444324183 scopus 로고    scopus 로고
    • Antineoplastic effect of immunostimulatory DNA (CpG-ODN) in a murine C57-BL6/ MB-49 transitional cell carcinoma model
    • Hegele A, Dalpke A, Barth P, et al. Antineoplastic effect of immunostimulatory DNA (CpG-ODN) in a murine C57-BL6/ MB-49 transitional cell carcinoma model. Anticancer Res. 2004;24: 2225-2230.
    • (2004) Anticancer Res , vol.24 , pp. 2225-2230
    • Hegele, A.1    Dalpke, A.2    Barth, P.3
  • 12
    • 24144434714 scopus 로고    scopus 로고
    • Immunostimulatory CpG oligonucleotides reduce tumor burden after intravesical administration in an orthotopic murine bladder cancer model
    • Hegele A, Dalpke A, Heeg K, et al. Immunostimulatory CpG oligonucleotides reduce tumor burden after intravesical administration in an orthotopic murine bladder cancer model. Tumour Biol. 2005;26:274-280.
    • (2005) Tumour Biol , vol.26 , pp. 274-280
    • Hegele, A.1    Dalpke, A.2    Heeg, K.3
  • 13
    • 0027179385 scopus 로고
    • T-cell subsets required for intravesical BCG immunotherapy for bladder cancer
    • Ratliff TL, Ritchey JK, Yuan JJ, et al. T-cell subsets required for intravesical BCG immunotherapy for bladder cancer. J Urol. 1993;150:1018-1023.
    • (1993) J Urol , vol.150 , pp. 1018-1023
    • Ratliff, T.L.1    Ritchey, J.K.2    Yuan, J.J.3
  • 14
    • 26044456143 scopus 로고    scopus 로고
    • Cytometric bead array (CBA) for the measurement of cytokines in urine and plasma of patients undergoing renal rejection
    • Jimenez R, Ramirez R, Carracedo J, et al. Cytometric bead array (CBA) for the measurement of cytokines in urine and plasma of patients undergoing renal rejection. Cytokine. 2005;32:45-50.
    • (2005) Cytokine , vol.32 , pp. 45-50
    • Jimenez, R.1    Ramirez, R.2    Carracedo, J.3
  • 15
    • 2442667692 scopus 로고    scopus 로고
    • Adenovirus CD40 ligand gene therapy counteracts immune escape mechanisms in the tumor microenvironment
    • Loskog A, Dzojic H, Vikman S, et al. Adenovirus CD40 ligand gene therapy counteracts immune escape mechanisms in the tumor microenvironment. J Immunol. 2004;172:7200-7205.
    • (2004) J Immunol , vol.172 , pp. 7200-7205
    • Loskog, A.1    Dzojic, H.2    Vikman, S.3
  • 16
    • 0142188693 scopus 로고    scopus 로고
    • Intratumoral vaccination with vaccinia-expressed tumor antigen and granulocyte macrophage colony-stimulating factor overcomes immunological ignorance to tumor antigen
    • Yang AS, Monken CE, Lattime EC. Intratumoral vaccination with vaccinia-expressed tumor antigen and granulocyte macrophage colony-stimulating factor overcomes immunological ignorance to tumor antigen. Cancer Res. 2003;63:6956-6961.
    • (2003) Cancer Res , vol.63 , pp. 6956-6961
    • Yang, A.S.1    Monken, C.E.2    Lattime, E.C.3
  • 17
    • 0038404925 scopus 로고    scopus 로고
    • Tumor-induced interleukin 10 suppresses the ability of splenic dendritic cells to stimulate CD4 and CD8 T-cell responses
    • Yang AS, Lattime EC. Tumor-induced interleukin 10 suppresses the ability of splenic dendritic cells to stimulate CD4 and CD8 T-cell responses. Cancer Res. 2003;63:2150-2157.
    • (2003) Cancer Res , vol.63 , pp. 2150-2157
    • Yang, A.S.1    Lattime, E.C.2
  • 18
    • 0033557968 scopus 로고    scopus 로고
    • Tumor-induced interleukin-10 inhibits type 1 immune responses directed at a tumor antigen as well as a non-tumor antigen present at the tumor site
    • Halak BK, Maguire HC Jr, Lattime EC. Tumor-induced interleukin-10 inhibits type 1 immune responses directed at a tumor antigen as well as a non-tumor antigen present at the tumor site. Cancer Res. 1999;59:911-917.
    • (1999) Cancer Res , vol.59 , pp. 911-917
    • Halak, B.K.1    Maguire Jr, H.C.2    Lattime, E.C.3
  • 19
    • 29344432052 scopus 로고    scopus 로고
    • AdCD40L gene therapy counteracts T regulatory cells and cures aggressive tumors in an orthotopic bladder cancer model
    • Loskog AS, Fransson ME, Totterman TT. AdCD40L gene therapy counteracts T regulatory cells and cures aggressive tumors in an orthotopic bladder cancer model. Clin Cancer Res. 2005;11:8816-8821.
    • (2005) Clin Cancer Res , vol.11 , pp. 8816-8821
    • Loskog, A.S.1    Fransson, M.E.2    Totterman, T.T.3
  • 20
    • 0034889255 scopus 로고    scopus 로고
    • Potent antitumor effects of CD154 transduced tumor cells in experimental bladder cancer
    • Loskog A, Bjorkland A, Brown MP, et al. Potent antitumor effects of CD154 transduced tumor cells in experimental bladder cancer. J Urol. 2001;166:1093-1097.
    • (2001) J Urol , vol.166 , pp. 1093-1097
    • Loskog, A.1    Bjorkland, A.2    Brown, M.P.3
  • 21
    • 0345711634 scopus 로고    scopus 로고
    • Optimizing syngeneic orthotopic murine bladder cancer (MB49)
    • Gunther JH, Jurczok A, Wulf T, et al. Optimizing syngeneic orthotopic murine bladder cancer (MB49). Cancer Res. 1999;59:2834-2837.
    • (1999) Cancer Res , vol.59 , pp. 2834-2837
    • Gunther, J.H.1    Jurczok, A.2    Wulf, T.3
  • 22
    • 0035371645 scopus 로고    scopus 로고
    • NK cells are essential for effective BCG immunotherapy
    • Brandau S, Riemensberger J, Jacobsen M, et al. NK cells are essential for effective BCG immunotherapy. Int J Cancer. 2001;92:697-702.
    • (2001) Int J Cancer , vol.92 , pp. 697-702
    • Brandau, S.1    Riemensberger, J.2    Jacobsen, M.3
  • 23
    • 0036837453 scopus 로고    scopus 로고
    • Intravesical bacillus Calmette-Guerin reduces the risk of progression in patients with superficial bladder cancer: A meta-analysis of the published results of randomized clinical trials
    • Sylvester RJ, van der MA, Lamm DL. Intravesical bacillus Calmette-Guerin reduces the risk of progression in patients with superficial bladder cancer: a meta-analysis of the published results of randomized clinical trials. J Urol. 2002;168:1964-1970.
    • (2002) J Urol , vol.168 , pp. 1964-1970
    • Sylvester, R.V.D.M.1    Lamm, D.L.2
  • 24
    • 0034455083 scopus 로고    scopus 로고
    • Immunology of bacille Calmette-Guerin and related topics
    • Wittes RC. Immunology of bacille Calmette-Guerin and related topics. Clin Infect Dis. 2000;31:59-63.
    • (2000) Clin Infect Dis , vol.31 , pp. 59-63
    • Wittes, R.C.1
  • 25
    • 33748085674 scopus 로고    scopus 로고
    • Neutrophil granulocytes are required for effective bacillus Calmette-Guerin immunotherapy of bladder cancer and orchestrate local immune responses
    • Suttmann H, Riemensberger J, Bentien G, et al. Neutrophil granulocytes are required for effective bacillus Calmette-Guerin immunotherapy of bladder cancer and orchestrate local immune responses. Cancer Res. 2006;66:8250-8257.
    • (2006) Cancer Res , vol.66 , pp. 8250-8257
    • Suttmann, H.1    Riemensberger, J.2    Bentien, G.3
  • 26
    • 33846912817 scopus 로고    scopus 로고
    • Macrophages are essential for antitumour effects against weakly immunogenic murine tumours induced by class B CpG-oligodeoxynucleotides
    • Buhtoiarov IN, Sondel PM, Eickhoff JC, et al. Macrophages are essential for antitumour effects against weakly immunogenic murine tumours induced by class B CpG-oligodeoxynucleotides. Immunology. 2007;120:412-423.
    • (2007) Immunology , vol.120 , pp. 412-423
    • Buhtoiarov, I.N.1    Sondel, P.M.2    Eickhoff, J.C.3
  • 27
    • 0141992946 scopus 로고    scopus 로고
    • Intratumor CpG- oligodeoxynucleotide injection induces protective antitumor T cell immunity
    • Lonsdorf AS, Kuekrek H, Stern BV, et al. Intratumor CpG- oligodeoxynucleotide injection induces protective antitumor T cell immunity. J Immunol. 2003;171:3941-3946.
    • (2003) J Immunol , vol.171 , pp. 3941-3946
    • Lonsdorf, A.S.1    Kuekrek, H.2    Stern, B.V.3
  • 29
    • 18844380660 scopus 로고    scopus 로고
    • Signaling in B cells via Toll-like receptors
    • Peng SL. Signaling in B cells via Toll-like receptors. Curr Opin Immunol. 2005;17:230-236.
    • (2005) Curr Opin Immunol , vol.17 , pp. 230-236
    • Peng, S.L.1
  • 30
    • 33746880685 scopus 로고    scopus 로고
    • Distinct responses of lung and spleen dendritic cells to the TLR9 agonist CpG oligodeoxynucleotide
    • Chen L, Arora M, Yarlagadda M, et al. Distinct responses of lung and spleen dendritic cells to the TLR9 agonist CpG oligodeoxynucleotide. J Immunol. 2006;177:2373-2383.
    • (2006) J Immunol , vol.177 , pp. 2373-2383
    • Chen, L.1    Arora, M.2    Yarlagadda, M.3
  • 31
    • 33748691678 scopus 로고    scopus 로고
    • Role of Th1-stimulating cytokines in bacillus Calmette-Guerin (BCG)-induced macrophage cytotoxicity against mouse bladder cancer MBT-2 cells
    • Luo Y, Yamada H, Evanoff DP, et al. Role of Th1-stimulating cytokines in bacillus Calmette-Guerin (BCG)-induced macrophage cytotoxicity against mouse bladder cancer MBT-2 cells. Clin Exp Immunol. 2006;146:181-188.
    • (2006) Clin Exp Immunol , vol.146 , pp. 181-188
    • Luo, Y.1    Yamada, H.2    Evanoff, D.P.3
  • 32
    • 0035500280 scopus 로고    scopus 로고
    • NK- and CD8(+) T cell-mediated eradication of established tumors by peritumoral injection of CpG-containing oligodeoxynucleotides
    • Kawarada Y, Ganss R, Garbi N, et al. NK- and CD8(+) T cell-mediated eradication of established tumors by peritumoral injection of CpG-containing oligodeoxynucleotides. J Immunol. 2001;167:5247-5253.
    • (2001) J Immunol , vol.167 , pp. 5247-5253
    • Kawarada, Y.1    Ganss, R.2    Garbi, N.3
  • 33
    • 0034532681 scopus 로고    scopus 로고
    • Bacterial CpG-DNA activates dendritic cells in vivo: T helper cell-independent cytotoxic T cell responses to soluble proteins
    • Sparwasser T, Vabulas RM, Villmow B, et al. Bacterial CpG-DNA activates dendritic cells in vivo: T helper cell-independent cytotoxic T cell responses to soluble proteins. Eur J Immunol. 2000;30:3591-3597.
    • (2000) Eur J Immunol , vol.30 , pp. 3591-3597
    • Sparwasser, T.1    Vabulas, R.M.2    Villmow, B.3
  • 34
    • 0037097633 scopus 로고    scopus 로고
    • Vaccination with tumor peptide in CpG adjuvant protects via IFN-gamma-dependent CD4 cell immunity
    • Stern BV, Boehm BO, Tary-Lehmann M. Vaccination with tumor peptide in CpG adjuvant protects via IFN-gamma-dependent CD4 cell immunity. J Immunol. 2002;168:6099-6105.
    • (2002) J Immunol , vol.168 , pp. 6099-6105
    • Stern, B.V.1    Boehm, B.O.2    Tary-Lehmann, M.3
  • 35
    • 0035936797 scopus 로고    scopus 로고
    • The TNF and TNF receptor superfamilies: Integrating mammalian biology
    • Locksley RM, Killeen N, Lenardo MJ. The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell. 2001;104:487-501.
    • (2001) Cell , vol.104 , pp. 487-501
    • Locksley, R.M.1    Killeen, N.2    Lenardo, M.J.3
  • 36
    • 0348223787 scopus 로고    scopus 로고
    • + regulatory T cells by TGF-beta induction of transcription factor Foxp3
    • + regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med. 2003;198:1875-1886.
    • (2003) J Exp Med , vol.198 , pp. 1875-1886
    • Chen, W.1    Jin, W.2    Hardegen, N.3
  • 37
  • 39
    • 33845311502 scopus 로고    scopus 로고
    • Human bladder carcinoma is dominated by T-regulatory cells and Th1 inhibitory cytokines
    • Loskog A, Ninalga C, Paul-Wetterberg G, et al. Human bladder carcinoma is dominated by T-regulatory cells and Th1 inhibitory cytokines. J Urol. 2007;177:353-358.
    • (2007) J Urol , vol.177 , pp. 353-358
    • Loskog, A.1    Ninalga, C.2    Paul-Wetterberg, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.