Human mesenchymal stem cells improve myocardial performance in a splenectomized rat model of chronic myocardial infarction

Journal of the Formosan Medical Association

Volumn 107, Issue 2, 2008, Pages 165-174

  Liu, Jen Fu ^a   Wang, Bao Wei ^a   Hung, Huei Fong ^a   Chang, Hang ^a   Shyu, Kou Gi ^a,b  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Cellular therapy; Mesenchymal stem cells; Myocardial infarction; Myocardial regeneration

Indexed keywords

TROPONIN T;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAPILLARY DENSITY; CHRONIC DISEASE; CONTROLLED STUDY; ECHOCARDIOGRAPHY; FLOW CYTOMETRY; HEART FUNCTION; HEART INFARCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE FIBROSIS; HEART PERFORMANCE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; IN VITRO STUDY; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MUSCLE DEVELOPMENT; MUSCLE REGENERATION; NONHUMAN; RAT; SPLENECTOMY;

EID: 40749091694     PISSN: 09296646     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0929-6646(08)60130-8     Document Type: Article

References (29)

1. Perin EC, Geng YJ, Willerson JT. Adult stem cell type in perspective. Circulation 2003;107:935-8.
2. Al-Radi OO, Rao VR, Li RK, et al. Cardiac cell transplantation: closer to bedside. Ann Thorac Surg 2003;75: S674-7.
3. Orlic D, Hill JM, Arai AE. Stem cell for myocardial regeneration. Circ Res 2002;91:1092-102.
4. Rafii S, Lyden D. Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration. Nat Med 2003;9:702-12.
5. Weissman IL. Translating stem and progenitor cell biology to the clinic: barriers and opportunities. Science 2000; 287:1442-6.
6. Kaji EH, Leiden JM. Gene and stem cell therapies. JAMA 2001;285:545-50.
7. Fukuda D. Development of regenerative cardiomyocytes from mesenchymal stem cells for cardiovascular tissue engineering. Artif Organs 2001;25:187-93.
8. Sussman M. Cardiovascular biology. Hearts and bones. Nature 2001;410:640-1.
9. Shyu KG, Wang BW, Hung HF, et al. Mesenchymal stem cells are superior to angiogenic growth factor genes for improving myocardial performance in the mouse model of acute myocardial infarction. J Biomed Sci 2006;13: 47-58.
10. Nagaya N, Fujii T, Iwase T, et al. Intravenous administration of mesenchymal stem cells improves cardiac function in rats with acute myocardial infarction through angiogenesis and myogenesis. Am J Physiol Heart Circ Physiol 2004; 287:H2670-6.
11. Piao H, Youn TJ, Kwon JS, et al. Effects of bone marrow-derived mesenchymal stem cells transplantation in acutely infarcting myocardium. Eur Heart J 2005;7:730-8.
12. Silva GV, Litovsky S, Assad JAR, et al. Mesenchymal stem cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a canine chronic ischemia model. Circulation 2005;111:150-6.
13. Makkar RR, Price MJ, Lill M, et al. Intramyocardial injection of allogenic bone marrow-derived mesenchymal stem cells without immunosuppression preserves cardiac function in a porcine model of myocardial infarction. J Cardiovasc Pharmacol Therapeut 2005;10:225-33.
14. Pittenger MF, Mackay AM, Beck SC, et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999;284:143-7.
15. Vasa M, Fichtlscherer S, Aicher A, et al. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res 2001;89:E1-7.
16. Shyu KG, Wang MT, Wang BW, et al. Intramyocardial injection of naked DNA encoding HIF-1α/VP16 hybrid to enhance angiogenesis in an acute myocardial infarction model in the rat. Cardiouasc Res 2002;54:576-83.
17. Rosenzweig A. Cardiac cell therapy - mixed results from mixed cells. N Engl J Med 2006;355:1274-7.
18. Brehm M, Strauer BE. Stem cell therapy in postinfarction chronic coronary heart disease. Nat Clin Pract Cardiovasc Med 2006;Suppl 1:S101-4.
19. Minguell JJ, Erices A. Mesenchymal stem cells and the treatment of cardiac disease. Exp Biol Med 2006;231:39-49.
20. Kinnaird T, Stabile E, Burnett MS, et al. Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms. Circ Res 2004;94:678-85.
21. Mangi A, Noiseux N, Kong D, et al. Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts. Nat Med 2003;9:1195-201.
22. Pittenger MF, Martin BJ. Mesenchymal stem cells and their potential as cardiac therapeutics. Circ Res 2004; 95:9-20.
23. Grinnemo KH, Mansson A, Dellgren G, et al. Xenoreactivity and engraftment of human mesenchymal stem cells transplanted into infarcted rat myocardium. J Thorac Cardiovasc Surg 2004;127:1293-300.
24. Heeschen C, Lehmann R, Honold J, et al. Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease. Circulation 2004;109:1615-22.
25. Rauscher FM, Goldschmidt-Clermont PJ, Davis BH, et al. Aging, progenitor cell exhaustion, and atherosclerosis. Circulation 2003;108:457-63.
26. Berry MF, Engler AJ, Woo J, et al. Mesenchymal stem cells injection after myocardial infarction improves myocardial compliance. Am J Physiol Heart Circ Physiol 2006;290: H2196-203.
27. Miyahara Y, Nagaya N, Kataoka M, et al. Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarction. Nat Med 2006;12:459-65.
28. Pfefer JM, Pfefer MA, Fletcher PJ, et al. Progressive ventricular remodeling in rat with myocardial infarction. Am J Physiol 1991;260:H1406-14.
29. Fishbein MC, Maclean D, Maroko PR. Experimental myocardial infarction in the rat: qualitative and quantitative changes during pathologic evolution. Am J Pathol 1978; 90:7-70.