Gene and stem cell therapies

JAMA

Volumn 285, Issue 5, 2001, Pages 545-550

  Kaji, Eugene H ^a,b,c   Leiden, Jeffrey M ^a,d  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL ISOLATION; DNA VECTOR; EMBRYO; EMBRYO CELL; GENE THERAPY; HUMAN; HUMAN CELL; PLASTICITY; PRIORITY JOURNAL; STEM CELL TRANSPLANTATION;

EID: 0035819463     PISSN: 00987484     EISSN: None     Source Type: Journal    
DOI: 10.1001/jama.285.5.545     Document Type: Article

References (46)

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7. Cell and gene therapy in Duchenne muscular dystrophy
8. Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia
9. Cancer gene therapy: Hard lessons and new courses
10. Cytostatic gene therapy for vascular proliferative disorders with a constitutively active form of the retinoblastoma gene product
11. Gene therapy for myocardial angiogenesis: Initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia
12. Complete cloning of the Duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals
13. The J.D. mutation in familial hypercholesterolemia: Amino acid substitution in cytoplasmic domain impedes internalization of LDL receptors
14. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
15. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
16. CpG motifs in bacterial DNA trigger direct B-cell activation
17. Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease
18. AAV vectors: Is clinical success on the horizon?
19. Lentiviral vectors: Turning a deadly foe into a therapeutic agent
20. Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector
21. Tissue-specific targeting of retroviral vectors through ligand-receptor interactions
22. Identification of a conserved receptor-binding site on the fiber proteins of CAR-recognizing adenoviridae
23. Regulated delivery of therapeutic proteins after in vivo somatic cell gene transfer
24. Long-term control of erythropoietin secretion by doxycycline in mice transplanted with engineered primary myoblasts
25. An adenoviral vector regulated by hypoxia for the treatment of ischaemic disease and cancer
26. Biocompatibility of cardiovascular gene delivery catheters with adenovirus vectors: An important determinant of the efficiency of cardiovascular gene transfer
27. Gene therapy's trials
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29. Prospective identification, isolation by flow cytometry, and in vivo self-renewal of multipotent mammalian neural crest stem cells
30. Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
31. Neuronal production, migration, and differentiation in a vocal control nucleus of the adult female canary brain
32. Dystrophin expression in the mdx mouse restored by stem cell transplantation
33. Dynamics of myoblast transplantation reveal a discrete minority of precursors with stem cell-like properties as the myogenic source
34. Turning brain into blood: A hematopoietic fate adopted by adult neural stem cells in vivo
35. Muscle regeneration by bone marrow-derived myogenic progenitors
36. Hematopoietic cells differentiate into both microglia and macroglia in the brains of adult mice
37. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains
38. Bone marrow as a potential source of hepatic oval cells
39. Viable offspring derived from fetal and adult mammalian cells
40. Embryonic stem cell lines derived from human blastocysts
41. Derivation of pluripotent stem cells from cultured human primordial germ cells
42. Derivation of completely cell culturederived mice from early-passage embryonic stem cells
43. Embryonic stem cell-derived glial precursors: A source of myelinating transplants
44. Systemic delivery of recombinant proteins by genetically modified myoblasts
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46. A time for restraint