Prognostic significance of CD44s expression in biliary tract cancers

Annals of Surgical Oncology

Volumn 15, Issue 4, 2008, Pages 1155-1160

  Lee, Sang Min ^a   Lee, Kyoung Eun ^a   Chang, Hye Jung ^a   Choi, Moon Young ^a   Cho, Min Sun ^a   Min, Seog Ki ^a   Lee, Hyeon Kook ^a   Mun, Yeung Chul ^a   Nam, Eun Mi ^a   Seong, Chu Myong ^a   Lee, Soon Nam ^a  

^a Ewha Womans University School of Medicine   (South Korea)

Author keywords

Biliary tract cancer; CD44s; CD44v6; Immunohistochemistry; Prognosis

Indexed keywords

CD44V6 ANTIGEN; HERMES ANTIGEN;

ADULT; AGED; ANTIGEN EXPRESSION; BILIARY TRACT CANCER; CANCER PATIENT; CANCER SURGERY; CANCER SURVIVAL; CANCER TISSUE; CONFERENCE PAPER; FEMALE; FOLLOW UP; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; POSTOPERATIVE PERIOD; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; SURVIVAL RATE; SURVIVAL TIME;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD44; BILIARY TRACT NEOPLASMS; FEMALE; GLYCOPROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; PROGNOSIS; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS;

EID: 40549115983     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-007-9786-9     Document Type: Conference Paper

References (20)

1. Choi YL, Xuan YH, Shin YK, et al. An immunohistochemical study of the expression of adhesion molecules in gallbladder lesions. J Histochem Cytochem 2004;52:591-601
2. Ponta H, Sherman L, Herrlich PA. CD44: from adhesion molecules to signalling regulators. Nat Rev Mol Cell Biol 2003;4:33-45
3. Sneath RJ, Mangham DC. The normal structure and function of CD44 and its role in neoplasia. Mol Pathol 1998;51:191-200
4. Kawano T, Nakamura Y, Yanoma S, et al. Expression of E-cadherin, and CD44s and CD44v6 and its association with prognosis in head and neck cancer. Auris Nasus Larynx 2004;31:35-41
5. Nihei Z, Ichikawa W, Kojima K, et al. The positive relationship between the expression of CD44 variant 6 and prognosis in colorectal cancer. Surg Today 1996;26:760-1
6. Nishimura S, Chung YS, Yashiro M, et al. CD44H plays an important role in peritoneal dissemination of scirrhous gastric cancer cells. Jpn J Cancer Res 1996;87:1235-44
7. Stauder R, Van Driel M, Schwarzler C, et al. Different CD44 splicing patterns define prognostic subgroups in multiple myeloma. Blood 1996;88:3101-8
8. Tempfer C, Losch A, Heinzl H, et al. Prognostic value of immunohistochemically detected CD44 isoforms CD44v5, CD44v6 and CD44v7-8 in human breast cancer. Eur J Cancer 1996;32A:2023-5
9. Stavropoulos NE, Filliadis I, Ioachim E, et al. CD44 standard form expression as a predictor of progression in high risk superficial bladder tumors. Int Urol Nephrol 2001;33:479-83
10. Goodison S, Urquidi V, Tarin D. CD44 cell adhesion molecules. Mol Pathol 1999;52:189-96
11. Kalekou H, Miliaras D. Immunohistochemical study of microvessel density, CD44 (standard form), p53 protein and c-erbB2 in gallbladder carcinoma. J Gastroenterol Hepatol 2004;19:812-8
12. Mikami T, Saegusa M, Mitomi H, et al. Significant correlations of E-cadherin, catenin, and CD44 variant form expression with carcinoma cell differentiation and prognosis of extrahepatic bile duct carcinomas. Am J Clin Pathol 2001;116:369-76
13. Yun KJ YK, Han WC. Immunohistochemical study for CD44v6 in hepatocellular carcinoma and cholangiocarcinoma. Cancer Res Treat 2002;34:170-4
14. Naor D, Nedvetzki S, Golan I, et al. CD44 in cancer. Crit Rev Clin Lab Sci 2002;39:527-79
15. Sugino T, Gorham H, Yoshida K, et al. Progressive loss of CD44 gene expression in invasive bladder cancer. Am J Pathol 1996;149:873-82
16. Nagano O, Saya H. Mechanism and biological significance of CD44 cleavage. Cancer Sci 2004;95:930-5
17. Yanagisawa N, Mikami T, Mitomi H, et al. CD44 variant overexpression in gallbladder carcinoma associated with tumor dedifferentiation. Cancer 2001;91:408-16
18. Faivre J, Forman D, Esteve J, et al. Survival of patients with primary liver cancer, pancreatic cancer and biliary tract cancer in Europe. Eur J Cancer 1998;34:2184-90
19. Nakeeb A, Pitt HA, Sohn TA, et al. Cholangiocarcinoma. A spectrum of intrahepatic, perihilar, and distal tumors. Ann Surg 1996;224:463-73
20. Yokoyama Y, Hiyama E, Murakami Y, et al. Lack of CD44 variant 6 expression in advanced extrahepatic bile duct/ampullary carcinoma. Cancer 1999;86:1691-9