The positive relationship between the expression of CD44 variant 6 and prognosis in colorectal cancer

Surgery Today

Volumn 26, Issue 9, 1996, Pages 760-761

  Nihei, Zenro ^a   Ichikawa, Wataru ^a   Kojima, Kazuyuki ^a   Togo, Sanetaka ^b   Miyanaga, Tadahiko ^b   Hirayama, Renzo ^a   Mishima, Yoshio ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b Tojun Hospital   (Japan)

Author keywords

CD44 variant 6; colorectal cancer; prognosis

Indexed keywords

HERMES ANTIGEN;

ARTICLE; CANCER CLASSIFICATION; CLINICAL ARTICLE; COLORECTAL CANCER; DISEASE ASSOCIATION; HUMAN; LIVER METASTASIS; PREDICTION; PROGNOSIS;

EID: 0029745762     PISSN: 09411291     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00312104     Document Type: Article

References (6)

1. Günthert U, Hofman M, Rudy W, Reber S, Zöller M, Haußmunn I, Matzku S, Wenzel A, Ponta H, Herrlich P (1991) A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells. Cell 66:13-24
2. Matsumura Y, Tarin D (1992) Significance of CD44 gene products for cancer diagnosis and disease evaluation. Lancet 340:1053-1058
3. Wielenga VJM, Heider KH, Offerhaus JA, Günther RA, van den Berg F, Ponta H, Herrlich P, Pals ST (1993) Expression of CD44 variant proteins in human colorectal cancer is related to tumor progression. Cancer Res. 53:4754-4756
4. Mulder JWR, Wielenga VJM, Polak MM, van den Berg F, Günther RA, Herrlich P, Pals ST, Offerhaus JA (1995) Expression of mutant p53 protein and CD44 variant proteins in colorectal tumorigenesis. Gut 36:76-80
5. Heider KH, Hofmann M, Hors E, van den Berg F, Ponta H, Herrlich P, Pals ST (1993) A human homologue of the rat metastasis-associated variant of CD44 is expressed in colorectal carcinomas and adenomatous polyps. J Cell Biol 120:227-233
6. Screaton GR, Bell MV, Jackson DG, Cornelis FB, Gerth U, Bell JI (1992) Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons. Proc Natl Acad Sci USA 89:12160-12164