Progressive loss of CD44 gene expression in invasive bladder cancer

American Journal of Pathology

Volumn 149, Issue 3, 1996, Pages 873-882

  Sugino, Takashi ^a   Gorham, Hazel ^a   Yoshida, Kazuhiro ^a   Bolodeoku, John ^a   Nargund, Vinod ^b   Cranston, David ^b   Goodison, Steve ^a   Tarin, David ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b CHURCHILL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HERMES ANTIGEN; MESSENGER RNA; MONOCLONAL ANTIBODY;

ARTICLE; BLADDER CANCER; CANCER INVASION; CLINICAL ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOUTHERN BLOTTING;

ANTIGENS, CD44; BASE SEQUENCE; BLOTTING, SOUTHERN; CARCINOMA, TRANSITIONAL CELL; GENE EXPRESSION; HUMANS; IN SITU HYBRIDIZATION; MOLECULAR SEQUENCE DATA; NEOPLASM INVASIVENESS; RETROSPECTIVE STUDIES; RNA, MESSENGER; RNA, NEOPLASM; URINARY BLADDER; URINARY BLADDER NEOPLASMS;

EID: 0029750232     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Matsumura Y, Tarin D: Significance of CD44 gene products for cancer diagnosis and disease evaluation. Lancet 1992, 340:1053-1058
2. Tarin D, Bolodeoku J, Hatfill SJ, Sugino T, Woodman A, Yoshida K: The clinical significance of malfunction of the CD44 locus in malignancy. J Neurol Oncol 1995, 26:209-219
3. Gunthert U, Hofmann M, Rudy W, Reber S, Zoller M, Haussmann I, Matzku S, Wenzel A, Ponta H, Herrlich P: A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells. Cell 1991, 65:13-24
4. Birch M, Mitchell S, Hart IR: Isolation and characterization of human melanoma cell variants expressing high and low levels of CD44. Cancer Res 1991, 51:6660-6667
5. Sy MS, Guo Y-J, Stamenkovic I: Distinct effects of two CD44 isoforms on tumor growth in vivo. J Exp Med 1991, 174:859-866
6. Merzak A, Koocheckpour S, Pilkington GJ: CD44 mediates human glioma cell adhesion and invasion in vitro. Cancer Res 1994, 54:3988-3992
7. Wielenga VJM, Heider K-H, Offerhaus GJA, Adolf GR, van den Berg FM, Ponta H, Herrlich P, Pals ST: Expression of CD44 variant proteins in human colorectal cancer is related to tumor progression. Cancer Res 1993, 53:4754-4756
8. Mulder J-WT, Kruyt PM, Sewnath M, Oosting J, Seldenrijk CA, Weidema WF, Offerhaus GJA, Pals ST: Colorectal cancer prognosis and expression of exon-v6-containing CD44 proteins. Lancet 1994, 344:1470-1472
9. Joensuu H, Klemi PJ, Toikkanen S, Jalkanen S: Glycoprotein CD44 expression and its association with survival in breast cancer. Am J Pathol 1993, 143:867-974
10. Kaufmann M, Heider KH, Sinn HP, von Minckwitz Gunter, Ponta H, Herrlich P: CD44 variant exon epitopes in primary breast cancer and length of survival. Lancet 1995, 345:615-619
11. Terpe HJ, Koopmann R, Imhof BA, Gunthert U: Expression of integrins and CD44 isoforms in non-Hodgkin's lymphomas: CD44 variant isoforms are preferentially expressed in high-grade malignant lymphomas. J Pathol 1994, 174:89-100
12. Washington K, Gottfried MR, Telen MJ: Expression of the cell adhesion molecule CD44 in gastric adenocarcinomas. Hum Pathol 1994, 25:1043-1112
13. Kainz C, Kohlberger P, Sliutz G, Tempfer C, Heinzl H, Reinthaller A, Breitenecker G, Koelbl H: Splice variants of CD44 in human cervical cancer stage IB to IIB. Gynecol Oncol 1995, 57:383-387
14. Hong RL, Pu YS, Hsieh TS, Chu JS, Lee WJ: Expression of E-cadherin and exon V6-containing isoforms of CD44 and their prognostic values in human transitional cell carcinoma. J Urol 1995, 153:2025-2028
15. Gross N, Beretta C, Peruisseau G, Jackson D, Simmons D, Beck D: CD44H expression by human neuroblastoma cells: relation to MYCN amplification and lineage differentiation. Cancer Res 1994, 54:4238-4242
16. Fujita N, Yaegashi N, Ide Y, Sato S, Nakamura M, Ishikawa I, Yajima A: Expression of CD44 in normal versus tumor endometrial tissues: possible implication of reduced expression of CD44 in lymph-vascular space involvement of cancer cells. Cancer Res 1994, 54:3992-3928
17. Salmi M, Grron-Virta K, Sointu P, Grenman R, Kalimo H, Jalkanen S: Regulated expression of exon v6 containing isoforms of CD44 in man: down regulation during malignant transformation of tumors of squamocellular origin. J Cell Biol 1993, 122:431-442
18. Clarke MR, Landreneau RJ, Resnick NM, Crowley R, Dougherty G, Cooper DL, Youssem SA: Prognostic significance of CD44 expression in adenocarcinoma of the lung. J Clin Pathol Mol Pathol 1995, 4:200-204
19. Bostwick DG: Natural history of early bladder cancer. J Cell Biochem 1992, 161(suppl):31-38
20. Melamed MR: Papillary tumors of the bladder. J Cell Biochem 1992, 161(suppl):44-47
21. Matsumura Y, Hanbury D, Smith J, Tarin D: Non-invasive detection of malignancy by identification of unusual CD44 gene activity in exfoliated cancer cells. Br Med J 1994, 308:691-624
22. Sugiyama M, Woodman A, Sugino T, Crowley S, Ho K, Smith J, Matsumura Y, Tarin D: Non-invasive detection of bladder cancer by identification of abnormal CD44 proteins in exfoliated cancer cells in urine, J Clin Pathol Mol Pathol 1995, 48:142-143
23. Borgya A, Woodman A, Sugiyama M, Donie F, Kopetzki E, Matsumura Y, Tarin D: Isolation and characterisation of antibodies which specifically recognise the peptide encoded by exon 7 (v2) of the human CD44 gene. J Clin Pathol Mol Pathol 1995, 5:241-250
24. Gorham H, Sugino T, Bolodeoku J, Yoshida K, Goodison S, Tarin D: Distribution of CD44 messenger RNA in archival paraffin wax embedded tumours and normal tissues viewed by in situ hybridisation. J Clin Pathol Mol Pathol 1996, 49:1-4
25. Czerniak B, Cohen GL, Etkind P, Dietch D, Simmons H, Herz F, Koss LG: Concurrent mutations of coding and regulatory sequences of the Ha-ras gene in urinary bladder carcinomas. Hum Pathol 1992, 23:1199-1204
26. Matsumura Y, Sugiyama M, Matsumura S, Hayle AJ, Robinson P, Smith JC, Tarin D: Unusual retention of introns in CD44 gene transcripts in bladder cancer provides new diagnostic and clinical oncological opportunities. J Pathol 1995, 177:11-20
27. Yoshida K, Bolodeoku J, Sugino T, Goodtson S, Matsumura Y, Warren BF, Toge T, Tahara E, Tarin D: Abnormal retention of intron 9 in CD44 gene transcripts in human gastrointestinal tumors. Cancer Res 1995, 55:4273-4277
28. Higashikawa K, Yokozaki H, Ue T, Taniyama K, Ishikawa T, Tarin D, Tahara E: Evaluation of CD44 transcription variants in human digestive tract carcinomas and normal tissues, Int J Cancer 1996 (in press)
29. Friedrichs K, Franke F, Lisboa BW, Kugler G, Gille I, Terpe H-J, Holzel F, Maass H, Gunthert U: CD44 isoforms correlate with cellular differentiation but not with prognosis in human breast cancer. Cancer Res 1995, 55:5424-5433
30. Liebert M, Washington R, Wedemeyer G, Carey TE, Grossman HB: Loss of co-localization of α6β4 integrin and collagen VII in bladder cancer. Am J Pathol 1994, 144:787-795
31. Aruffo A, Stamenkovic M, Melnick CB, Underbill B, Seed B: CD44 is the principal cell surface receptor for hyaluronate. Cell 1990, 61:1303-1313
32. Neame SJ, Isacke CM: The cytoplasmic tail of CD44 is required for basolateral localization in epithelial MDCK cells but does not mediate association with the detergent-insoluble cytoskeleton of fibroblasts. J Cell Biol 1993, 121:1299-1310