Transcriptional and posttranscriptional control of tyrosine hydroxylase gene expression during persistent stimulation of pituitary adenylate cyclase- activating polypeptide receptors on PC12 cells: Regulation by protein kinase A-dependent and protein kinase A-independent pathways

Journal of Neurochemistry

Volumn 71, Issue 2, 1998, Pages 478-486

  Corbitt, James ^a   Vivekananda, Jeevalatha ^b   Wang, Shou Shu ^b   Strong, Randy ^a,b,c  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

Author keywords

Gene transcription; MRNA stability; Pituitary adenylate cyclase activating polypeptide (PACAP); Tyrosine hydroxylase; Tyrosine hydroxylase mRNA

Indexed keywords

ADENYLATE CYCLASE ACTIVATOR; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; DEXAMETHASONE; HISTIDINE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE RECEPTOR; ISOLEUCINE; SECRETIN; TYROSINE 3 MONOOXYGENASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CATECHOLAMINE RELEASE; CONTROLLED STUDY; DRUG MECHANISM; GENE EXPRESSION REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR UPREGULATION; TRANSCRIPTION REGULATION;

ANIMALIA;

EID: 0031784630     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.71020478.x     Document Type: Article

References (58)

1. Arimura A. (1992) Pituitary adenylate cyclase activating polypeptide (PACAP): discovery and current status of research. Regul. Pept. 37, 287-303.
2. Black I. B., Adler J. E., Dreyfus C. F., Friedman W. F., Lagamma E. F., and Roach A. H. (1987) Biochemistry of information storage in the nervous system. Science 236, 1263-1268.
3. Bradford M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
4. Cavallaro S., D'Agata V., Guadabasso V., Travali S., Stivala F., and Canonico P. L. (1995) Differentiation induces pituitary adenylate cyclase-activating polypeptide receptor expression in PC-12 cells. Mol. Pharmacol. 48, 56-62.
5. Chomczynski P. and Sacchi N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
6. Chow J. and Dennis P. P. (1994) Coupling between mRNA synthe-sis and mRNA stability in Escherichia coli. Mol. Microbiol. 11, 919-931.
7. Christophe J. (1993) Type I receptors for PACAP (a neuropeptide even more important than VIP?). Biochim. Biophys. Acta 1154, 183-199.
8. Craviso G. L., Hemelt V. B., Waymire J. C., Mihaylova-Todorova S. T., Fernandez E., and Moore R. (1996) Posttranscriptional control of tyrosine hydroxylase induction during continuous nicotinic receptor activation of bovine adrenal chromaffin cells, in Stress: Molecular Genetic and Neurobiological Advances, Vol. 2 (McCarty R., Aguilera G., Sabban E., and Kvetnansky R., eds), pp. 663-675. Gordon and Breach Science Publishers S.A., New York.
9. Czyzyk-Krzeska M. F. and Beresh J. E. (1996) Characterization of the hypoxia-inducible protein binding site within the pyrimidine-rich tract in the 3′-untranslated region of the tyrosine hydroxylase mRNA. J. Biol. Chem. 271, 3293-3299.
10. Czyzyk-Krzeska M. F., Furnari B. A., Lawson E. E., and Millhorn D. E. (1994a) Hypoxia increases rate of transcription and stability of tyrosine hydroxylase mRNA in pheochromocytoma (PC12) cells. J. Biol. Chem. 269, 760-764.
11. Czyzyk-Krzeska M. F., Dominski Z., Kole R., and Millhorn D. E. (1994b) Hypoxia stimulates binding of a cytoplasmic protein to a pyrimidine-rich sequence in the 3′-untranslated region of rat tyrosine hydroxylase mRNA. J. Biol. Chem. 269, 9940-9945.
12. Czyzyk-Krzeska M. F., Paulding W., Beresh J. E., and Kroll S. L. (1997) Post-transcriptional regulation of tyrosine hydroxylase gene expression by oxygen in PC12 cells. Kidney Int. 51, 585-590.
13. Damon D. H., D'Amore P. A., and Wagner J, A. (1990) Nerve growth factor and fibroblast growth factor regulate neurite outgrowth and gene expression in PC12 cells via both protein kinase C- and cAMP-independent mechanisms. J. Cell Biol. 110, 1333-1339.
14. Deutsch P. J. and Sun Y. (1992) The 38 amino acid form of pituitary adenylate cyclase activating polypeptide stimulates dual signalling cascades in PC12 cells and promotes neurite outgrowth. J. Biol. Chem. 267, 5108-5113.
15. Elango N., Vivekananda J., Strong R., and Katz M. S. (1997) Nuclei isolation from bone cells for nuclear run-on assays. Biotechniques 23, 422-424.
16. Fluharty S. J., Snyder G. L., Stricker E. M., and Zigmond M. J. (1983) Short- and long-term changes in adrenal tyrosine hydroxylase activity during insulin-induced hypoglycemia and cold stress. Brain Res. 267, 384-387.
17. Fossom L. H., Sterling C. R., and Tank A. W. (1992) Regulation of tyrosine hydroxylase gene transcription rate and tyrosine hydroxylase mRNA stability by cyclic AMP and glucocorticoid. Mol. Pharmacol. 42, 898-908.
18. Ginty D. D., Glowacka D., Bader D. S., Hidaka H., and Wagner J. A. (1991) Induction of immediate early genes by Ca2+ influx requires cAMP-dependent protein kinase in PC12 cells. J. Biol. Chem. 266, 17454-17458.
19. Greene L. A. and Tischler A. S. (1976) Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Natl. Acad. Sci. USA 73, 2424-2428.
20. Guidotti A. and Costa E. (1977) Trans-synaptic regulation of tyrosine 3′-monooxygenase biosynthesis in the adrenal medulla. Biochem. Pharmacol. 26, 817-823.
21. Guo X. and Wakade A. R. (1994) Differential secretion of catecholamines in response to peptidergic and cholinergic transmitters in rat adrenals. J. Physiol. (Lond.) 475, 539-545.
22. Gutierrez G. E., Mundy G. R., Derynck R., Hewlett E. L., and Katz M. S. (1987) Inhibition of parathyroid hormone-responsive adenylate cyclase in clonal osteoblast-like cells by transforming growth factor alpha epidermal growth factor. J. Biol. Chem. 262, 15845-15850.
23. Hanbauer I., Lovenberg W., Guidotti A., and Costa E. (1975) Role of cholinergic and glucocorticosteroid receptors in the tyrosine hydroxylase induction elicited by reserpine in superior cervical ganglion. Brain Res. 96, 197-200.
24. Haycock J. W. (1990) Phosphorylation of tyrosine hydroxylase in situ at serine 8, 19, 31 and 40. J. Biol. Chem. 265, 11682-11691.
25. Haycock J. W. (1996) Short- and long-term regulation of tyrosine hydroxylase in chromaffin cells by VIP and PACAP. Ann. NY Acad. Sci. 805, 219-230.
26. Haycock J. W. and Wakade A. R. (1992) Activation and multiplesite phosphorylation of tyrosine hydroxylase in perfused rat adrenal glands. J. Neurochem. 58, 57-64.
27. Ip N. Y., Perlman R. L., and Zigmond R. E. (1983) Acute transsynaptic regulation of tyrosine 3-monooxygenase activity in the rat superior cervical ganglion: evidence for both cholinergic and noncholinergic mechanisms. Proc. Natl. Acad. Sci. USA 80, 2081-2085.
28. Isobe K., Nakai T., and Takuwa Y. (1993) Ca(2+)-dependent stimulatory effect of pituitary adenylate cyclase-activating polypeptide on catecholamine secretion from cultured porcine adrenal medullary chromaffin cells. Endocrinology 132, 1757-1765.
29. Isobe K., Yukimasa N., Nakai T., and Takuwa Y. (1996) Pituitary adenylate cyclase-activating polypeptide induces gene expression of the catecholamine synthesizing enzymes, tyrosine hydroxylase and dopamine beta hydroxylase, through 3′,5′-cyclic adenosine monophosphate- and protein kinase C-dependent mechanisms in cultured porcine adrenal medullary cells. Neuropeptides 30, 167-175.
30. Kim K. S., Lee M. K., Carrol J., and Joh T. H. (1993a) Both the basal and inducible transcription of the tyrosine hydroxylase gene are dependent upon a cAMP response element. J. Biol. Chem. 268, 15689-15695.
31. Kirn K. S., Park D. H., Wessel T. C., Song B., Wagner J. A., and Joh T. H. (1993b) A dual role for the cAMP-dependent protein kinase in tyrosine hydroxylase expression. Proc. Natl. Acad. Sci. USA 90, 3471-3475.
32. Malhotra R. K. and Wakade A. R. (1987) Vasoactive intestinal polypeptide stimulates the secretion of catecholamines from the rat adrenal gland. J. Physiol. (Lond.) 388, 285-294.
33. Marley P. D., Cheung C. Y., Thomson K. A., and Murphy R. (1996) Activation of tyrosine hydroxylase by pituitary adenylate cyclase-activating polypeptide (PACAP-27) in bovine adrenal chromaffin cells. J. Auton. Nerv. Syst. 60, 141-146.
34. May V. and Braas K. M. (1995) Pituitary adenylate cyclase-activating polypeptide (PACAP) regulation of sympathetic neuron neuropeptide Y and catecholamine expression. J. Neurochem. 65, 978-987.
35. McCracken S., Fong N., Yankulov K., Ballantyne S., Pan G., Greenblatt J. S., Patterson D., Wickens M., and Bentley D. L. (1997) The C-terminal domain of RNA polymerase II couples mRNA processing to transcription. Nature 385, 357-361.
36. Mueller R. A., Thoenen H., and Axelrod J. (1970) Inhibition of neurally induced tyrosine hydroxylase by nicotinic receptor blockade. Eur. J. Pharmacol. 10, 51-56.
37. Muller A., Monnier D., Rene F., Larmet Y., Koch B., and Loeffler J.-P. (1997) Pituitary adenylate cyclase-activating polypeptide triggers dual signaling in CATH.a cells and transcriptionally activates tyrosine hydroxylase and c-fos expression. J. Neurochem. 68, 1696-1704.
38. Otten U. and Thoenen H. (1975) Circadian rhythm of tyrosine hydroxylase induction by short-term cold stress: modulatory action of glucocorticoids in newborn and adult rats. Proc. Natl. Acad. Sci. USA 72, 1415-1419.
39. Otten U. and Thoenen H. (1976) Selective induction of tyrosine hydroxylase and dopamine beta-hydroxylase in sympathetic ganglia in organ culture: role of glucocorticoids as modulators. Mol. Pharmacol. 12, 353-361.
40. Otten U., Paravicini U., Oesch F., and Thoenen H. (1973) Time requirement for the single steps of trans-syhaptic induction of tyrosine hydroxylase in the peripheral sympathetic nervous system. Naunyn Schmiedebergs Arch. Pharmacol. 280, 117-127.
41. Rius R. A., Guidotti A., and Costa E. (1994) Pituitary adenylate cyclase activating polypeptide (PACAP) potently enhances tyrosine hydroxylase (TH) in adrenal chromaffin cells. Life Sci. 54, 1735-1743.
42. Roskoski R. Jr., White L., Knowlton R., and Roskoski L. M. (1989) Regulation of tyrosine hydroxylase activity in rat PC12 cells by neuropeptides of the secretin family. Mol. Pharmacol. 36, 925-931.
43. Sabban E. L. (1996) Synthesis of dopamine and its regulation, in CNS Neurotransmitters and Neuromodulators: Dopamine (Stone T. W., ed), pp. 1-20. CRC Press, Boca Raton, Florida.
44. Sabban E. L. (1997) Control of tyrosine hydroxylase gene expression in chromaffin and PC12 cells. Semin. Cell Dev. Biol. 8, 101-111.
45. Schadlow V. C., Barzilai N., and Deutsch P. J. (1992) Regulation of gene expression in PC12 cells via an activator of dual second messengers: pituitary adenylate cyclase activating polypeptide. Mol. Biol. Cell 3, 941-951.
46. Stachowiak M. K., Stricker E. M., Zigmond M. J., and Kaplan B. B. (1988) A cholinergic antagonist blocks cold stress-induced alterations in rat adrenal tyrosine hydroxylase mRNA. Mol. Brain Res. 3, 193-196.
47. Thoenen H. (1970) Induction of tyrosine hydroxylase in peripheral and central adrenergic neurones by cold exposure of rats. Nature 228, 861-862.
48. Thoenen H., Mueller R. A., and Axelrod J. (1969) Trans-synaptic induction of adrenal tyrosine hydroxylase. J. Pharmacol. Exp. Ther. 169, 249-254.
49. Van Buskirk R., Corcoran T., and Wagner J. A. (1985) Clonal variants of PC12 pheochromocytoma cells with defects in cAMP-dependent protein kinases induce ornithine decarboxylase in response to nerve growth factor but not to adenosine agonists. Mol. Cell. Biol. 5, 1984-1992,
50. Vyas S., Biguet N. F., and Mallet J. (1990) Transcriptional and post-transcriptional regulation of tyrosine hydroxylase gene by protein kinase C. EMBO J. 9, 3707-3712.
51. Watanabe T., Shimamoto N., Takahashi A., and Fujino M. (1995) PACAP stimulates catecholamine release from adrenal medulla: a novel noncholinergic secretagogue. Am. J. Physiol. 269, E903-E909.
52. Waymire J. C., Craviso G. L., Lichteig K., Johnston J. P., Baldwin C., and Zigmond R. E. (1991) Vasoactive intestinal peptide stimulates catecholamine biosynthesis in isolated adrenal chromaffin cells: evidence for a cyclic AMP-dependent phosphorylation and activation of tyrosine hydroxylase. J. Neurochem. 57, 1313-1324.
53. Wessels-Reiker M., Haycock J. W., Howlett A. C., and Strong R. (1991) Vasoactive intestinal polypeptide induces tyrosine hydroxylase in PC12 cells. J. Biol. Chem. 266, 9347-9350.
54. Wessels-Reiker M., Basiboina R., Hewlett A. C, and Strong R. (1993) Vasoactive intestinal polypeptide-related peptides modulate tyrosine hydroxylase gene expression in PC12 cells through multiple adenylate cyclase-coupled receptors. J. Neurochem. 60, 1018-1029.
55. Zhou H., Manji S. S., Findlay D. M., Martin T. J., Heath J. K., and Ng K. W. (1994) Novel action of retinoic acid. Stabilization of newly synthesized alkaline phosphatase transcripts. J. Biol. Chem. 269, 22433-22439.
56. Zigmond R. E. (1988) A comparison of the long-term and short-term regulations of tyrosine hydroxylase activity. J. Physiol. (Paris) 83, 267-271.
57. Zigmond R. E. and Bowers C. W. (1981) Influence of nerve activity of the macromolecular content of neurons and their effector organs. Annu. Rev. Physiol. 43, 673-687.
58. Zigmond R. E., Schwarzschild M. A., and Rittenhouse A. R. (1989) Acute regulation of tyrosine hydroxylase by nerve activity and by neurotransmitters via phosphorylation. Annu. Rev. Neurosci. 12, 415-461.