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Volumn 5, Issue 1, 2008, Pages 70-74

Emerging the role of the structure of brain membrane targets recognizing glutamate

Author keywords

Glutamate conformation; Glutamate transporter; Ionotropic glutamate receptor; Metabotropic glutamate receptor; PDB database analysis

Indexed keywords

AMINO ACID TRANSPORTER; GLUTAMATE RECEPTOR; GLUTAMIC ACID; GUANINE NUCLEOTIDE BINDING PROTEIN; ION CHANNEL; IONOTROPIC RECEPTOR; METABOTROPIC RECEPTOR;

EID: 40549108925     PISSN: 15701638     EISSN: None     Source Type: Journal    
DOI: 10.2174/157016308783769496     Document Type: Review
Times cited : (1)

References (31)
  • 2
    • 17744387125 scopus 로고    scopus 로고
    • Ionotropic and metabotropic glutamate receptor structure and pharmacology
    • Kew J.N.C., Kemp J.A.: Ionotropic and metabotropic glutamate receptor structure and pharmacology. Psychopharmacology 179(1), 4, (2005).
    • (2005) Psychopharmacology , vol.179 , Issue.1 , pp. 4
    • Kew, J.N.C.1    Kemp, J.A.2
  • 3
    • 33645321641 scopus 로고    scopus 로고
    • Glutamate receptors at atomic resolution
    • Mayer M.L.: Glutamate receptors at atomic resolution. Nature 440(7083), 456, (2006).
    • (2006) Nature , vol.440 , Issue.7083 , pp. 456
    • Mayer, M.L.1
  • 4
    • 7244254186 scopus 로고    scopus 로고
    • Structure of a glutamate transporter homologue from Pyrococcus horikoshii
    • Yernool D., Boudker O., Jin Y., Gouaux E.: Structure of a glutamate transporter homologue from Pyrococcus horikoshii. Nature 431(7010), 811, (2004).
    • (2004) Nature , vol.431 , Issue.7010 , pp. 811
    • Yernool, D.1    Boudker, O.2    Jin, Y.3    Gouaux, E.4
  • 5
    • 33846505059 scopus 로고    scopus 로고
    • Coupling substrate and ion binding to extracellular gate of a sodium dependent aspartate transporter
    • Boudker O., Ryan R.M., Yernool D., Shimamoto K., Gouaux E.: Coupling substrate and ion binding to extracellular gate of a sodium dependent aspartate transporter. Nature 445(7126), 387, (2007).
    • (2007) Nature , vol.445 , Issue.7126 , pp. 387
    • Boudker, O.1    Ryan, R.M.2    Yernool, D.3    Shimamoto, K.4    Gouaux, E.5
  • 6
    • 34248572483 scopus 로고    scopus 로고
    • Gate Movements in Glutamate Transporters
    • Kanner B.I.: Gate Movements in Glutamate Transporters. ACS Chem. Biol. 2(3), 166, (2007).
    • (2007) ACS Chem. Biol , vol.2 , Issue.3 , pp. 166
    • Kanner, B.I.1
  • 7
    • 0033636314 scopus 로고    scopus 로고
    • Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: Crystal structure of the GluR2 ligand binding core
    • Armstrong N., Gouaux E.: Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structure of the GluR2 ligand binding core. Neuron 28(1), 165, (2000).
    • (2000) Neuron , vol.28 , Issue.1 , pp. 165
    • Armstrong, N.1    Gouaux, E.2
  • 10
    • 0036843081 scopus 로고    scopus 로고
    • The dance of the clams: Twists and turns in the family C GPCR homodimer
    • Jensen A.A., Greenwood J.R., Bräuner-Osborne H.: The dance of the clams: twists and turns in the family C GPCR homodimer. Trends Pharmacol. Sci. 23(11), 491, (2002).
    • (2002) Trends Pharmacol. Sci , vol.23 , Issue.11 , pp. 491
    • Jensen, A.A.1    Greenwood, J.R.2    Bräuner-Osborne, H.3
  • 12
    • 0014280059 scopus 로고
    • New looks and outlooks on physical enzymology
    • Eigen M.: New looks and outlooks on physical enzymology. Q. Rev. Biophys. 1(1), 3, (1968).
    • (1968) Q. Rev. Biophys , vol.1 , Issue.1 , pp. 3
    • Eigen, M.1
  • 13
    • 78651189765 scopus 로고
    • On the nature of allosteric transitions: A plausible model
    • Monod J., Wyman J., Changeux J. P.: On the nature of allosteric transitions: a plausible model. J. Mol. Biol. 12, 88, (1965).
    • (1965) J. Mol. Biol , vol.12 , pp. 88
    • Monod, J.1    Wyman, J.2    Changeux, J.P.3
  • 14
    • 0001858251 scopus 로고
    • Application of a Theory of Enzyme Specificity to Protein Synthesis
    • Koshland D.E.: Application of a Theory of Enzyme Specificity to Protein Synthesis. Proc. Natl. Acad. Sci. USA. 44(2), 98, (1958).
    • (1958) Proc. Natl. Acad. Sci. USA , vol.44 , Issue.2 , pp. 98
    • Koshland, D.E.1
  • 15
    • 0013863816 scopus 로고
    • Comparison of Experimental Binding Data and Theoretical Models in Proteins Containing Subunits
    • Koshland D.E., Némethy G., Filmer D.: Comparison of Experimental Binding Data and Theoretical Models in Proteins Containing Subunits. Biochemistry 5(1), 365, (1966).
    • (1966) Biochemistry , vol.5 , Issue.1 , pp. 365
    • Koshland, D.E.1    Némethy, G.2    Filmer, D.3
  • 16
    • 0043033172 scopus 로고    scopus 로고
    • Structural basis for partial agonist action at ionotropic glutamate receptors
    • Jin R., Banke T.G., Mayer M.L., Traynelis S.F., Gouaux E.: Structural basis for partial agonist action at ionotropic glutamate receptors. Nat. Neurosci. 6(8), 803, (2003).
    • (2003) Nat. Neurosci , vol.6 , Issue.8 , pp. 803
    • Jin, R.1    Banke, T.G.2    Mayer, M.L.3    Traynelis, S.F.4    Gouaux, E.5
  • 17
    • 0035576829 scopus 로고    scopus 로고
    • Universality of receptor channel responses
    • Kardos J., Nyikos L.: Universality of receptor channel responses. Trends Pharmacol. Sci. 22(12), 642, (2001).
    • (2001) Trends Pharmacol. Sci , vol.22 , Issue.12 , pp. 642
    • Kardos, J.1    Nyikos, L.2
  • 18
    • 0037319323 scopus 로고    scopus 로고
    • Binding sites, singly bound states, and conformation coupling shape GABA-evoked currents
    • Mozrzymas J.W., Barberis A., Mercik K., Żarnowska E.D.: Binding sites, singly bound states, and conformation coupling shape GABA-evoked currents. J. Neurophysiol. 89(2), 871, (2003).
    • (2003) J. Neurophysiol , vol.89 , Issue.2 , pp. 871
    • Mozrzymas, J.W.1    Barberis, A.2    Mercik, K.3    Żarnowska, E.D.4
  • 19
    • 0036762866 scopus 로고    scopus 로고
    • Ligand-specific conformations of an ionotropic glutamate receptor
    • Nyikos L., Simon Á., Barabás P., Kardos J.: Ligand-specific conformations of an ionotropic glutamate receptor. Protein. Eng. 15(9), 717, (2002).
    • (2002) Protein. Eng , vol.15 , Issue.9 , pp. 717
    • Nyikos, L.1    Simon, A.2    Barabás, P.3    Kardos, J.4
  • 20
    • 0042208459 scopus 로고    scopus 로고
    • Crystallizing our understanding of partial agonists
    • Weiss D., Chang Y.: Crystallizing our understanding of partial agonists. Nat. Neurosci. 6(8), 788, (2003).
    • (2003) Nat. Neurosci , vol.6 , Issue.8 , pp. 788
    • Weiss, D.1    Chang, Y.2
  • 21
    • 0038625032 scopus 로고    scopus 로고
    • Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes
    • Armstrong N., Mayer M., Gouaux E.: Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes. Proc. Natl. Acad. Sci. USA. 100(10), 5741, (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , Issue.10 , pp. 5741
    • Armstrong, N.1    Mayer, M.2    Gouaux, E.3
  • 22
    • 0036483593 scopus 로고    scopus 로고
    • The structure and function of glutamate receptor ion channel
    • Madden D. R.: The structure and function of glutamate receptor ion channel. Nat. Rev. Neurosci. 3(2), 91, (2002).
    • (2002) Nat. Rev. Neurosci , vol.3 , Issue.2 , pp. 91
    • Madden, D.R.1
  • 23
    • 0036591660 scopus 로고    scopus 로고
    • The ligand paradox between affinity and efficacy: Can you be there and not make a difference?
    • Kenakin T., Onaran O.: The ligand paradox between affinity and efficacy: can you be there and not make a difference? Trends Pharmacol. Sci. 23(6), 275, (2002).
    • (2002) Trends Pharmacol. Sci , vol.23 , Issue.6 , pp. 275
    • Kenakin, T.1    Onaran, O.2
  • 24
    • 0036683420 scopus 로고    scopus 로고
    • Ion channels: Does each subunit do something on its own?
    • Karpen J. W., Ruiz M.: Ion channels: does each subunit do something on its own? Trends Biochem. Sci. 27(8), 402, (2002).
    • (2002) Trends Biochem. Sci , vol.27 , Issue.8 , pp. 402
    • Karpen, J.W.1    Ruiz, M.2
  • 25
    • 13844266202 scopus 로고    scopus 로고
    • Crystal structures of the GluR5 and GluR6 ligand binding cores: Molecular mechanisms underlying kainate receptor selectivity
    • Mayer M. L.: Crystal structures of the GluR5 and GluR6 ligand binding cores: Molecular mechanisms underlying kainate receptor selectivity. Neuron 45(4), 539, (2005).
    • (2005) Neuron , vol.45 , Issue.4 , pp. 539
    • Mayer, M.L.1
  • 26
    • 33646588654 scopus 로고    scopus 로고
    • Pharmacological insights obtained from structure-function studies of ionotropic glutamate receptors
    • Chen E.P., Wyllie D.J.A.: Pharmacological insights obtained from structure-function studies of ionotropic glutamate receptors. Brit. J. Pharmacol. 147(8), 839, (2006).
    • (2006) Brit. J. Pharmacol , vol.147 , Issue.8 , pp. 839
    • Chen, E.P.1    Wyllie, D.J.A.2
  • 27
    • 0031551577 scopus 로고    scopus 로고
    • Stabilization centers in proteins: Identification, characterization and predictions
    • Dosztányi Zs., Fiser A., Simon I.: Stabilization centers in proteins: identification, characterization and predictions. J. Mol. Biol. 272(4), 597, (1997).
    • (1997) J. Mol. Biol , vol.272 , Issue.4 , pp. 597
    • Dosztányi, Z.1    Fiser, A.2    Simon, I.3
  • 29
    • 33646353703 scopus 로고    scopus 로고
    • Suppression of neuronal network excitability and seizure-like events by 2-methyl-4-oxo-3H-quinazoline-3-acetyl piperidine in juvenile rat hippocampus: Involvement of a metabotropic glutamate receptor
    • Lasztóczi B., Emri Zs., Szárics É., Héja L., Simon Á., Nyikos L., Kardos J.: Suppression of neuronal network excitability and seizure-like events by 2-methyl-4-oxo-3H-quinazoline-3-acetyl piperidine in juvenile rat hippocampus: Involvement of a metabotropic glutamate receptor. Neurochem. Int. 49(1), 41, (2006).
    • (2006) Neurochem. Int , vol.49 , Issue.1 , pp. 41
    • Lasztóczi, B.1    Emri, Z.2    Szárics, E.3    Héja, L.4    Simon, A.5    Nyikos, L.6    Kardos, J.7
  • 30
    • 33745617041 scopus 로고    scopus 로고
    • Target structure-based modeling of the glutamate transporter pharmacophore
    • Simon Á., Bencsura Á., Kardos J.: Target structure-based modeling of the glutamate transporter pharmacophore. Lett. Drug Des. Disc. 3, 293, (2006).
    • (2006) Lett. Drug Des. Disc , vol.3 , pp. 293
    • Simon, A.1    Bencsura, A.2    Kardos, J.3
  • 31
    • 33846448786 scopus 로고    scopus 로고
    • Crystallographic refinement of ligand complexes
    • Kleywegt G.J.: Crystallographic refinement of ligand complexes. Acta. Crystallogr. D. Biol. Crystallogr. 63(Pt 1), 94, (2007).
    • (2007) Acta. Crystallogr. D. Biol. Crystallogr , vol.63 , Issue.PART 1 , pp. 94
    • Kleywegt, G.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.