A deletion in the R region of long terminal repeats in small ruminant lentiviruses is associated with decreased pathology in the lung

Veterinary Journal

Volumn 175, Issue 3, 2008, Pages 346-355

  Angelopoulou, K ^a   Poutahidis, T ^a   Brellou, G D ^a   Greenland, T ^b   Vlemmas, I ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b UMR 754   (France)

Author keywords

Deletion; LTR; MVV; Productive infection; SRLV

Indexed keywords

VIRUS PROTEIN;

ANIMAL TISSUE; ARTICLE; BRAIN INFECTION; CONTROLLED STUDY; GENE DELETION; GENE SEQUENCE; GENETIC VARIABILITY; HETEROZYGOTE; HISTOPATHOLOGY; LONG TERMINAL REPEAT; LUNG INFECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENICITY; PROTEIN EXPRESSION; RETROVIRUS INFECTION; RUMINANT STOMACH; SHEEP DISEASE; UDDER; VIRUS STRAIN; VIRUS VIRULENCE; VISNA VIRUS;

ANIMALS; BRAIN; CASE-CONTROL STUDIES; DNA PRIMERS; DNA, VIRAL; IMMUNOHISTOCHEMISTRY; LENTIVIRUS; LENTIVIRUS INFECTIONS; LUNG; MAMMARY GLANDS, ANIMAL; POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SEQUENCE DELETION; SHEEP; SHEEP DISEASES; TERMINAL REPEAT SEQUENCES;

ANIMALIA; OVIS ARIES; SMALL RUMINANT LENTIVIRUS; VISNA/MAEDI VIRUS;

EID: 40449109116     PISSN: 10900233     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tvjl.2007.01.025     Document Type: Article

References (40)

1. Agnarsdottir G., Thorsteinsdottir H., Oskarsson T., Matthiasdottir S., Haflidadottir B., Andresson O.S., and Andresdottir V. The long terminal repeat is a determinant of cell tropism of maedi-visna virus. Journal of General Virology 81 (2000) 1901-1905
2. Angelopoulou K., Karanikolaou K., Papanastasopoulou M., Koumpati-Artopiou M., Vlemmas I., Papadopoulos O., and Koptopoulos G. First partial characterization of small ruminant lentiviruses from Greece. Veterinary Microbiology 109 (2005) 1-9
3. Angelopoulou K., Brellou G.D., and Vlemmas I. Detection of maedi-visna virus in the kidneys of naturally infected sheep. Journal of Comparative Pathology 134 (2006) 329-335
4. Angelopoulou K., Brellou G.D., Greenland T., and Vlemmas I. A novel deletion in the LTR region of a Greek small ruminant lentivirus may be associated with low pathogenicity. Virus Research 118 (2006) 178-184
5. Barros S.C., Ramos F., Duarte M., Fagulha T., Cruz B., and Fevereiro M. Genomic characterization of a slow/low maedi visna virus. Virus Genes 29 (2004) 199-210
6. Barros S.C., Andresdottir V., and Fevereiro M. Cellular specificity and replication rate of maedi visna virus in vitro can be controlled by LTR sequences. Archives of Virology 150 (2005) 201-213
7. Bolea R., Monleon E., Carrasco L., Vargas A., de Andrec D., Amorena B., Badiola J.J., and Lujan L. Maedi-visna virus infection of ovine mammary epithelial cells. Veterinary Research 37 (2006) 133-144
8. Brodie S.J., Marcom K.A., Pearson L.D., Anderson B.C., de la Concha-Bermejillo A., Ellis J.A., and DeMartini J.C. The effects of virus load in the pathogenesis of the lentivirus-induced lymphoid interstitial pneumonia. Journal of Infectious Diseases 166 (1992) 531-541
9. Brodie S.J., Pearson L.D., Zink M.C., Bickle H.M., Anderson B.C., Marcom K.A., and DeMartini J.C. Ovine lentivirus expression and disease. Virus replication, but not entry, is restricted to macrophages of specific tissues. American Journal of Pathology 146 (1995) 250-263
10. Campbell B.J., and Avery R.J. Sequence analysis and transcriptional activity of the LTR of OLV-CU1, a North American ovine lentivirus. Journal of General Virology 77 (1996) 2999-3004
11. Carrozza M.L., Mazzei M.B., Bandecchi P., Arispici M., and Tolari F. In situ PCR-associated immunohistochemistry identifies cell types harbouring the maedi-visna virus genome in tissue sections of sheep infected naturally. Journal of Virological Methods 107 (2003) 121-127
12. Clements J.E., and Payne S.L. Molecular basis of the pathobiology of lentiviruses. Virus Research 32 (1994) 97-109
13. Clements J.E., and Zink M.C. Molecular biology and pathogenesis of animal lentivirus infections. Clinical Microbiology Reviews 9 (1996) 100-117
14. Craig L.E., Nealen M.L., Strandberg J.D., and Zink M.C. Different replication of ovine lentivirus in endothelial cells cultured from different tissues. Virology 238 (1997) 316-326
15. Extramiana A.B., González L., Cortabarría N., García M., and Juste R.A. Evaluation of a PCR technique for the detection of maedi-visna proviral DNA in blood, milk and tissue samples of naturally infected sheep. Small Ruminant Research 44 (2002) 109-118
16. Gabuzda D.H., Hess J.L., Small J.A., and Clements J. Regulation of the visna virus long terminal repeat in macrophages involves cellular factors that bind sequences containing AP-1 sites. Molecular and Cellular Biology 9 (1989) 2728-2733
17. Gdovin S., and Clements J. Molecular mechanisms of visna virus tat: identification of the targets for transcriptional activation and evidence for a post-transcriptional effect. Virology 188 (1992) 438-450
18. Gendelman H.E., Narayan O., Kennedy-Stoskopf S., Kennedy P.G.E., Ghotbi Z., Clements J.E., Stanley J., and Pezeshkpour G. Tropism of sheep lentiviruses for monocytes: susceptibility to infection and virus gene expression increase during maturation of monocytes to macrophages. Journal of Virology 58 (1986) 67-74
19. Georgsson G., Houwers D.J., Palsson P.A., and Petursson G. Expression of viral-antigens in the central nervous-system of visna-infected sheep - An immunohistochemical study on experimental visna induced by virus-strains of increased neurovirulence. Acta Neuropathologica 77 (1989) 299-306
20. Gudmundsson B., Jonsson S.R., Olafsson O., Agnarsdottir G., Matthi{dotless}asdottir S., Georgsson G., Torsteinsdottir S., Svansson V., Kristbjornsdottir H.B., Franzdottir S.R., Andresson O.S., and Andresdotti V. Simultaneous mutations in CA and vif of maedi-visna virus cause attenuated replication in macrophages and reduced infectivity in vivo. Journal of Virology 79 (2005) 15038-15042
21. Hess J.L., Pyper J.M., and Clements J.E. Nucleotide sequence and transcriptional activity of the caprine arthritis encephalitis virus long terminal repeat. Journal of Virology 60 (1986) 385-393
22. Hess J.L., Small J.A., and Clements J. Sequences in the visna virus long terminal repeat that control transcriptional activity and respond to viral transactivation: involvement of AP-1 sites in basal activity and transactivation. Journal of Virology 63 (1989) 3001-3010
23. Houwers, D.J., 1988. Ovine lentivirus infections. Aspects of immunology, pathology, epidemiology and control. Doctoral thesis. University of Utrecht.
24. Karanikolaou K., Angelopoulou K., Papanastasopoulou M., Koumpati-Artopiou M., Papadopoulos O., and Koptopoulos G. Detection of small ruminant lentiviruses by PCR and serology tests in field samples of animals from Greece. Small Ruminant Research 58 (2005) 181-187
25. Lairmore M.D., Akita G., Russell H., and DeMartini J.C. Replication and cytopathic effects of ovine lentivirus strains in alveolar macrophages correlate with in vivo pathogenicity. Journal of Virology 61 (1987) 4038-4042
26. Lee W.C., McConnell I., and Blacklaws B.A. Electron microscopic studies of the replication of a British isolate of maedi-visna virus in macrophages and skin cell lines. Veterinary Microbiology 49 (1996) 93-104
27. Leroux C., Chastang J., Greenland T., and Mornex J.F. Genomic heterogeneity of small ruminant lentiviruses: existence of heterogeneous populations in sheep and of the same lentiviral genotypes in sheep and goats. Archives of Virology 142 (1997) 1125-1137
28. Murphy B.G., Hötzel I., Jasmer D.P., Davis W.C., and Knowles D. TNFα and GM-CSF-induced activation of the CAEV promoter is independent of AP-1. Virology 352 (2006) 188-199
29. Narayan O., and Clements J. Biology and pathogenesis of lentiviruses. Journal of General Virology 70 (1989) 1617-1639
30. Narayan O., Wolinsky J.S., Clements J.C., Strandberg J.D., Griffin D.E., and Cork L.C. Slow virus replication: the role of the macrophage in the persistence and the expression of visna viruses of sheep and goats. Journal of General Virology 59 (1982) 345-356
31. Pépin M., Vitu C., Russo P., Mornex J.F., and Peterhans E. Maedi-visna virus infection in sheep: a review. Veterinary Research 29 (1998) 341-367
32. Ravazzolo A.P., Nenci C., Vogt H.-R., Waldvogel A., Obexer-Ruff G., Peterhans E., and Bertoni G. Viral load, organ distribution, histopathological lesions, and cytokine mRNA expression in goats infected with a molecular clone of the caprine arthritis encephalitis virus. Virology 350 (2006) 116-127
33. Reis J.K.P., Craigo J.K., Cook S.J., Issel C.J., and Montelaro R.C. Characterization of EIAV LTR variability and compartmentalization in various reservoir tissues of long-term inapparent carrier ponies. Virology 311 (2003) 169-180
34. Sargan D., Sutton K., Bennet I., McConnell I., and Harkiss G. Sequence and repeat structure variants in the long terminal repeat of maedi-visna virus EV-1. Virology 208 (1995) 343-348
35. Sonigo P., Alizon M., Staskus K., Klatzmann D., Cole S., Danos O., Retzel E., Tiollais P., Haase A., and Wain-Hobson S. Nucleotide sequence of the visna lentivirus: relationship to the AIDS virus. Cell 42 (1985) 369-382
36. Sutton K., Lin C.-T., Harkiss G., Mcconnell I., and Sargan D. Regulation of the long terminal repeat in visna virus by a transcription factor related to the AML/PEBP2/CBF superfamily. Virology 229 (1997) 240-250
37. Thompson J.D., Higgins D.G., and Gibson T.J. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Research 22 (1994) 4673-4680
38. Zhang Z., Watt N.J., Hopkins J., Harkiss G., and Woodall C.J. Quantitative analysis of maedi-visna virus DNA load in peripheral blood monocytes and alveolar macrophages. Journal of Virological Methods 86 (2000) 13-20
39. Zink M.C., and Johnson L.K. Pathobiology of lentivirus infections of sheep and goats. Virus Research 32 (1994) 139-154
40. Zink M.C., Yager J.A., and Myers J.D. Pathogenesis of caprine arthritis encephalitis virus. Cellular localization of viral transcripts in tissues of infected goats. American Journal of Pathology 136 (1990) 843-854