Simultaneous mutations in CA and Vif of maedi-visna virus cause attenuated replication in macrophages and reduced infectivity in vivo

Journal of Virology

Volumn 79, Issue 24, 2005, Pages 15038-15042

  Gudmundsson, Bjarki ^a   Jónsson, Stefán Ragnar ^a,b   Ólafsson, Oddur ^a   Agnarsdóttir, Gudrún ^a   Matthíasdóttir, Sigrídur ^a   Georgsson, Gudmundur ^a   Torsteinsdóttir, Sigurbjorg ^a   Svansson, Vilhjálmur ^a   Kristbjornsdóttir, Helga Bryndís ^a   Franzdóttir, Sigrídur Rut ^a   Andrésson, Ólafur S ^a   Andrésdóttir, Valgerdur ^a  

^a UNIVERSITY OF ICELAND   (Iceland)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; LEUCINE; PROLINE; SERINE; VIF PROTEIN;

ADOLESCENT; AMINO ACID SUBSTITUTION; ANTIVIRAL ACTIVITY; ARTICLE; CA DOMAIN; CELL LINE; CENTRAL NERVOUS SYSTEM DISEASE; ENVELOPE GENE; GENE DELETION; IN VIVO STUDY; LENTIVIRINAE; LUNG DISEASE; MACROPHAGE; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SHEEP; SHEEP DISEASE; VIROGENESIS; VIRUS ATTENUATION; VIRUS GENE; VIRUS INFECTIVITY; VIRUS INHIBITION; VIRUS MUTATION; VIRUS REPLICATION; VIRUS VIRULENCE; VISNA VIRUS; VISNA VIRUS KS1; VISNA VIRUS KV1772;

ANIMALS; DNA, VIRAL; GENE PRODUCTS, VIF; GENOME, VIRAL; MACROPHAGES; MUTATION; SHEEP; SHEEP DISEASES; VIRUS REPLICATION; VISNA-MAEDI VIRUS;

LENTIVIRUS; OVIS ARIES; PRIMATES; VISNA/MAEDI VIRUS;

EID: 29744456189     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.79.24.15038-15042.2005     Document Type: Article

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