메뉴 건너뛰기




Volumn 40, Issue 1, 2004, Pages 9-19

Antiretroviral activity and pharmacokinetics properties of lamivudine and zidovudine association;Atividade anti-retroviral e propriedades farmacocinéticas da associação entre lamivudina e zidovudina

Author keywords

Antiretroviral drugs; Lamivudine; Pharmacokinetics; Zidovudine

Indexed keywords

ANTIRETROVIRUS AGENT; COTRIMOXAZOLE; FLUCONAZOLE; LAMIVUDINE; NUCLEOSIDE DERIVATIVE; RNA DIRECTED DNA POLYMERASE; TRANSCRIPTASE; ZIDOVUDINE;

EID: 4043161323     PISSN: 15169332     EISSN: None     Source Type: Journal    
DOI: 10.1590/s1516-93322004000100004     Document Type: Review
Times cited : (8)

References (43)
  • 1
    • 0029968585 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of zidovudine
    • ACOSTA, E. P.; PAGE, L. M.; FLETCHER, C. V. Clinical pharmacokinetics of zidovudine. Clin. Pharm., v. 30, n. 4, p. 251-262, 1996.
    • (1996) Clin. Pharm. , vol.30 , Issue.4 , pp. 251-262
    • Acosta, E.P.1    Page, L.M.2    Fletcher, C.V.3
  • 3
    • 84862393060 scopus 로고    scopus 로고
    • Infecções virais
    • Page, C. P.; Curtis, M. J.; Sutter, M. C.; Walker, M. J. A.; Hoffman, B. B. São Paulo: Manole
    • AOKI, F. Y. Infecções virais. In: PAGE, C. P.; CURTIS, M. J.; SUTTER, M. C.; WALKER, M. J. A.; HOFFMAN, B. B. Farmacologia Integrada. São Paulo: Manole, 1999. p. 445-460.
    • (1999) Farmacologia Integrada , pp. 445-460
    • Aoki, F.Y.1
  • 4
    • 0034698425 scopus 로고    scopus 로고
    • Determination of twelve antiretroviral agents in human plasma sample using reversed-phase high-performance liquid chromatography
    • AYMARD, G.; LEGRAND, M.; TRICHEREAU, N.; DIQUET, B. Determination of twelve antiretroviral agents in human plasma sample using reversed-phase high-performance liquid chromatography. J. Chromatogr. B, v. 744, p. 227-240, 2000.
    • (2000) J. Chromatogr. B , vol.744 , pp. 227-240
    • Aymard, G.1    Legrand, M.2    Trichereau, N.3    Diquet, B.4
  • 5
    • 0035057018 scopus 로고    scopus 로고
    • Antiretroviral therapeutic possibilities for human immunodeficiency virus/acquired imunodeficiency syndrome
    • BALINT, G. A. Antiretroviral therapeutic possibilities for human immunodeficiency virus/acquired imunodeficiency syndrome. Pharmacol. Ther., v 89, p. 17-27, 2001.
    • (2001) Pharmacol. Ther. , vol.89 , pp. 17-27
    • Balint, G.A.1
  • 6
    • 0032955402 scopus 로고    scopus 로고
    • Pharmacokinetics and potential interactions amongst antiretroviral agents used to treat patients with HIV infection
    • BARRY, M.; MULCAHY, F.; MERRY, C.; GIBBONS, S.; BACK, D. Pharmacokinetics and potential interactions amongst antiretroviral agents used to treat patients with HIV infection. Clin. Pharmacokinet., v. 36, n. 4, p. 289-304, 1999.
    • (1999) Clin. Pharmacokinet. , vol.36 , Issue.4 , pp. 289-304
    • Barry, M.1    Mulcahy, F.2    Merry, C.3    Gibbons, S.4    Back, D.5
  • 7
    • 0023680670 scopus 로고
    • Pharmacokinetics and biovailability of zidovudine in humans
    • S. 2A
    • BLUM, R.; LIAO, H. T. S.; GOOD, S. S.; MIRANDA, P. Pharmacokinetics and biovailability of zidovudine in humans. Am. J. Med., v. 85, S. 2A, p. 189-194, 1988.
    • (1988) Am. J. Med. , vol.85 , pp. 189-194
    • Blum, R.1    Liao, H.T.S.2    Good, S.S.3    Miranda, P.4
  • 8
    • 84862396276 scopus 로고    scopus 로고
    • Ministério da Saúde
    • BRASIL. Ministério da Saúde. Boletim epidemiológico - editorial. Disponível em 〈http://www.aids.gov.br/sitebol/inferior. htm〉. Acesso em: 01 de julho de 2002a.
    • Boletim Epidemiológico - Editorial
  • 9
    • 84862394309 scopus 로고    scopus 로고
    • Ministério da Saúde
    • BRASIL. Ministério da Saúde. Documentos, recomendações e relatórios técnicos. Disponível em 〈http://www.aids.gov.br/documentos.htm〉. Acesso em: 01 de julho de 2002b.
    • Documentos, Recomendações e Relatórios Técnicos
  • 10
    • 0031568694 scopus 로고    scopus 로고
    • Recent advances HIV-1 infection -I
    • COHN, J. A. Recent advances HIV-1 infection -I. BMJ., v. 314, p. 487-491, 1997.
    • (1997) BMJ , vol.314 , pp. 487-491
    • Cohn, J.A.1
  • 12
    • 0034104090 scopus 로고    scopus 로고
    • Efficacy, safety and adherence with a twice-daily combination lamivudine/zidovudine tablet formulation, plus a protease inhibitor, in HIV infection
    • ERON, J. J.; YETZER, E. S.; RUANE, P. J.; BECKER, S.; SAWYERR, G. A.; FISHER, R. L.; TOLSON, J. M.; SHAEFER, M. S. Efficacy, safety and adherence with a twice-daily combination lamivudine/zidovudine tablet formulation, plus a protease inhibitor, in HIV infection. AIDS., v. 14, n. 6, p. 671-681, 2000.
    • (2000) AIDS , vol.14 , Issue.6 , pp. 671-681
    • Eron, J.J.1    Yetzer, E.S.2    Ruane, P.J.3    Becker, S.4    Sawyerr, G.A.5    Fisher, R.L.6    Tolson, J.M.7    Shaefer, M.S.8
  • 14
    • 0033790624 scopus 로고    scopus 로고
    • Zidovudine triphosphate and lamivudine triphosphate concentration- response relationships in HIV-infected persons
    • FLETCHER, C. V; RAWLE, S. P.; KAKUDA, T. N.; ANDERSON, P. L.; WELLER, D.; LANE, R. B.; BRUNDAGE, R. C.; REMMEL, R. P. Zidovudine triphosphate and lamivudine triphosphate concentration-response relationships in HIV-infected persons. AIDS, v. 14, n. 14, p. 2137-2144, 2000.
    • (2000) AIDS , vol.14 , Issue.14 , pp. 2137-2144
    • Fletcher, C.V.1    Rawle, S.P.2    Kakuda, T.N.3    Anderson, P.L.4    Weller, D.5    Lane, R.B.6    Brundage, R.C.7    Remmel, R.P.8
  • 15
    • 0025669912 scopus 로고
    • Determination of 3'-azido-3'-deoxythymidine, 2',3'-dideoxycytidine, 3'-fluoro-3'-deoxythymidine and 2',3'-dideoxyinosine in biological samples by high-performance liquid chromatography
    • FRIJUS-PLESSEN, N.; MICHAELIS, H. C.; FOTH, H.; KAHL, G. F. Determination of 3'-azido-3'-deoxythymidine, 2',3'-dideoxycytidine, 3'-fluoro-3'- deoxythymidine and 2',3'-dideoxyinosine in biological samples by high-performance liquid chromatography. J. Chromatogr. Biom. Appl., v. 534, p. 101-107, 1990.
    • (1990) J. Chromatogr. Biom. Appl. , vol.534 , pp. 101-107
    • Frijus-Plessen, N.1    Michaelis, H.C.2    Foth, H.3    Kahl, G.F.4
  • 16
    • 84862397613 scopus 로고    scopus 로고
    • GLAXO - editorial. Disponível em 〈 http://www.glaxo.com. br〉. Acesso em: 01 de julho de 2002.
    • GLAXO - Editorial
  • 18
    • 0031613952 scopus 로고    scopus 로고
    • New antivirals and new combintions
    • HAVLIR, D. V.; LANGE, J. M. A. New antivirals and new combintions. AIDS, v. 12, Sup. A, p. S165-S174, 1998.
    • (1998) AIDS , vol.12 , Issue.SUPPL. A
    • Havlir, D.V.1    Lange, J.M.A.2
  • 19
    • 0028356833 scopus 로고
    • High-performance liquid chromatographic assay for 2'-deoxy-3'- thiacutidine in human serum
    • HARKER, A. J.; EVANS, G. L.; HAWLEY, A. E.; MORRIS, D. M. High-performance liquid chromatographic assay for 2'-deoxy-3'-thiacutidine in human serum. J. Chromatogr. B: Biom. Appl., v. 657, p. 227-232, 1994.
    • (1994) J. Chromatogr. B: Biom. Appl. , vol.657 , pp. 227-232
    • Harker, A.J.1    Evans, G.L.2    Hawley, A.E.3    Morris, D.M.4
  • 20
    • 0032402235 scopus 로고    scopus 로고
    • A randomized, controlled, double-blind study comparing the survival benefit of four different reverse transcriptase inhibitor therapies (three-drug, two-drug, and alternating drug) for the treatment of advanced AIDS
    • HENRY, K.; ERICE, A.; TIERNEY, C.; BALFOUR JR, H. H.; FISCHL, M. A.; KMACK, A.; LIOU, S. H.; KENTON, A.; HIRSCH, M. S.; PHAIR, J.; MARTINEZ, A.; KAHN, J. O. A randomized, controlled, double-blind study comparing the survival benefit of four different reverse transcriptase inhibitor therapies (three-drug, two-drug, and alternating drug) for the treatment of advanced AIDS. J. Acquir. Imm. Defic. Synd. and human retrovirol., v. 19, n. 4, p. 339-349, 1998.
    • (1998) J. Acquir. Imm. Defic. Synd. and Human Retrovirol. , vol.19 , Issue.4 , pp. 339-349
    • Henry, K.1    Erice, A.2    Tierney, C.3    Balfour, J.R.4    Fischl, H.H.5    Kmack, M.A.6    Liou, A.7    Kenton, S.H.8    Hirsch, A.9    Phair, M.S.10    Martinez, J.11    Kahn, A.J.O.12
  • 21
    • 0032427644 scopus 로고    scopus 로고
    • Quantitative determination of (-)-2'-deoxy-3'-thiacytidine (lamivudine) in human plasma, saliva and cerebrospinal fluid by high-performance liquid chromatography with ultraviolet detection
    • HOETELMANS, R. M. W.; PROFIJT, M.; MEENHORST, P. L.; MULDER, J. W.; BEIJNEN, J. H. Quantitative determination of (-)-2'-deoxy-3'-thiacytidine (lamivudine) in human plasma, saliva and cerebrospinal fluid by high-performance liquid chromatography with ultraviolet detection. J. Chromatogr. B., v. 713, p. 387-394, 1998.
    • (1998) J. Chromatogr. B , vol.713 , pp. 387-394
    • Hoetelmans, R.M.W.1    Profijt, M.2    Meenhorst, P.L.3    Mulder, J.W.4    Beijnen, J.H.5
  • 22
    • 0032568239 scopus 로고    scopus 로고
    • Pilot study of zidovudine-lamivudine combination therapy in vertical HIV-infected antiretroviral-naive children
    • HORNEFF, G.; ADANS, O.; WAHN, V. Pilot study of zidovudine-lamivudine combination therapy in vertical HIV-infected antiretroviral-naive children. AIDS, v. 12, n. 5, p. 489-494, 1998.
    • (1998) AIDS , vol.12 , Issue.5 , pp. 489-494
    • Horneff, G.1    Adans, O.2    Wahn, V.3
  • 24
    • 0030020718 scopus 로고    scopus 로고
    • Solubility behavior of lamivudine crystal forms in recrystallization solvents
    • Washington
    • JOZWIAKOWSKI, M. J.; NGUYEN, N. A. T.; SISCO, J. M.; SPANCAKE, C. W. Solubility behavior of lamivudine crystal forms in recrystallization solvents. J. Pharm. Sci., Washington, v. 85, n. 2, p. 193-199, 1996.
    • (1996) J. Pharm. Sci. , vol.85 , Issue.2 , pp. 193-199
    • Jozwiakowski, M.J.1    Nguyen, N.A.T.2    Sisco, J.M.3    Spancake, C.W.4
  • 25
  • 26
    • 0036437809 scopus 로고    scopus 로고
    • Antiretroviral pharmacokinetics in the paediatric population
    • KING, R. J.; KIMBERLIN, D. W.; ALDROVANDI, G. M.; ACOSTA, E. P. Antiretroviral pharmacokinetics in the paediatric population. Clin. Pharmacokinet., v. 44, n. 14, p. 1115-1133, 2002.
    • (2002) Clin. Pharmacokinet. , vol.44 , Issue.14 , pp. 1115-1133
    • King, R.J.1    Kimberlin, D.W.2    Aldrovandi, G.M.3    Acosta, E.P.4
  • 27
    • 1842423921 scopus 로고    scopus 로고
    • Physicochemical properties and stability of Epivir tablets
    • Osaka
    • KYOKO, H.; ETSUKO, U.; MASUMITSU, T. Physicochemical properties and stability of Epivir tablets. Kagaku Ryoho no Ryoiki, Osaka, v. 13, p. 1170-1172, 1997.
    • (1997) Kagaku Ryoho No Ryoiki , vol.13 , pp. 1170-1172
    • Kyoko, H.1    Etsuko, U.2    Masumitsu, T.3
  • 28
    • 0037662652 scopus 로고    scopus 로고
    • An in vivo pharmacokinetic/pharmacodynamic model for antiretroviral combination
    • LEGRAND, M.; COMETS, E.; AYMARD, G.; TUBIANA, R.; KATLAMA, C.; DIQUET, B. An in vivo pharmacokinetic/pharmacodynamic model for antiretroviral combination. HIV Clin. Trials., v. 4, n. 3, p. 170-83, 2003.
    • (2003) HIV Clin. Trials. , vol.4 , Issue.3 , pp. 170-183
    • Legrand, M.1    Comets, E.2    Aymard, G.3    Tubiana, R.4    Katlama, C.5    Diquet, B.6
  • 30
    • 0035943472 scopus 로고    scopus 로고
    • Simultaneous quantification of nicleoside HIV-1 reverse transcriptase inhibitors by short-end injection capillary eletrochromatography on a β-cyclodextrin-blonded silica stationary phase
    • MESPLET, N.; MORIN, P.; FRANÇOIS, C. AGROFOGLIO, L. A. Simultaneous quantification of nicleoside HIV-1 reverse transcriptase inhibitors by short-end injection capillary eletrochromatography on a β-cyclodextrin- blonded silica stationary phase. J. Chromatogr. A., v. 927, p. 161-168, 2001.
    • (2001) J. Chromatogr. A , vol.927 , pp. 161-168
    • Mesplet, N.1    Morin, P.2    François, C.3    Agrofoglio, L.A.4
  • 33
    • 0034488247 scopus 로고    scopus 로고
    • Simultaneous quantitation of the 5'- triphosphate metabolites of zidovudine, lamivudine, and stavudine in peripheral mononuclear blood cells of HIV infected patients by high-performance liquid chromatography tandem mass spectrometry
    • MOORE, J. D.; VALETTE, G.; DARQUE, A.; ZHOU, X. J.; SOMMADOSSI, J. P. Simultaneous quantitation of the 5'- triphosphate metabolites of zidovudine, lamivudine, and stavudine in peripheral mononuclear blood cells of HIV infected patients by high-performance liquid chromatography tandem mass spectrometry. J. Am. Soc. Mass Spectrom., v. 11, p. 1134-1143, 2000.
    • (2000) J. Am. Soc. Mass Spectrom. , vol.11 , pp. 1134-1143
    • Moore, J.D.1    Valette, G.2    Darque, A.3    Zhou, X.J.4    Sommadossi, J.P.5
  • 34
    • 0001024860 scopus 로고    scopus 로고
    • The pharmacokinetics of lamivudine phosphorilation in peripheral blood mononuclear cells from patients infected HIV-1
    • MOORE, K. H. P.; BARRETT, J. E.; SHAW, S.; PAKES, G. E.; CHURCHUS, R.; KAPPOR, A.; LLOYD, J.; BARRY, M. G.; BACK, D. The pharmacokinetics of lamivudine phosphorilation in peripheral blood mononuclear cells from patients infected HIV-1. AIDS, v. 13, n. 16, p. 2239-2250, 1999.
    • (1999) AIDS , vol.13 , Issue.16 , pp. 2239-2250
    • Moore, K.H.P.1    Barrett, J.E.2    Shaw, S.3    Pakes, G.E.4    Churchus, R.5    Kappor, A.6    Lloyd, J.7    Barry, M.G.8    Back, D.9
  • 35
    • 0033339123 scopus 로고    scopus 로고
    • Lamivudine/zidovudine as a combined formulation tablet: Bioequivalence compared with lamivudine and zidovudine administered concurrently and the effect of food on absorption
    • MOORE, K. H. P.; SHAW, S.; LAURENT, A. L.; LLOYD, P.; DUNCAN, B.; MORRIS, D. M.; O'MARA, M. J.; PAKES, G. E. Lamivudine/zidovudine as a combined formulation tablet: bioequivalence compared with lamivudine and zidovudine administered concurrently and the effect of food on absorption. J. Clin. Pharmacol., v. 39, p. 593-605, 1999.
    • (1999) J. Clin. Pharmacol. , vol.39 , pp. 593-605
    • Moore, K.H.P.1    Shaw, S.2    Laurent, A.L.3    Lloyd, P.4    Duncan, B.5    Morris, D.M.6    O'Mara, M.J.7    Pakes, G.E.8
  • 36
    • 0032870854 scopus 로고    scopus 로고
    • Drug monitoring of antiretroviral therapy for HIV-1 infection: Method validation and results of a pilot study
    • MOYER, T. P.; TEMESGEN, Z.; ENGER, R.; ESTES, L.; CHARLSON, J.; OLIVER, L.; WRIGHT, A. Drug monitoring of antiretroviral therapy for HIV-1 infection: method validation and results of a pilot study. Clin. Chem., v. 45, n. 9, p. 1465-1476, 1999.
    • (1999) Clin. Chem. , vol.45 , Issue.9 , pp. 1465-1476
    • Moyer, T.P.1    Temesgen, Z.2    Enger, R.3    Estes, L.4    Charlson, J.5    Oliver, L.6    Wright, A.7
  • 37
    • 0034717232 scopus 로고    scopus 로고
    • Simultaneous determination of lamivudine and zidovudine concentrations in human seminal plasma using high-performance liquid chromatography and tandem mass spectrometry
    • PEREIRA, A. S.; KENNEY, K. B.; COHEN, M. S.; HALL, J. E.; ERON, J. J.; TIDWELL, R. R.; DUNN, J. A. Simultaneous determination of lamivudine and zidovudine concentrations in human seminal plasma using high-performance liquid chromatography and tandem mass spectrometry. J. Chromatogr. B., v. 742, p. 173-183, 2000.
    • (2000) J. Chromatogr. B , vol.742 , pp. 173-183
    • Pereira, A.S.1    Kenney, K.B.2    Cohen, M.S.3    Hall, J.E.4    Eron, J.J.5    Tidwell, R.R.6    Dunn, J.A.7
  • 38
    • 0030899204 scopus 로고    scopus 로고
    • Lamivudine. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in the management of HIV infection
    • PERRY, C. M.; FAULDS, D. Lamivudine. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in the management of HIV infection. Drugs, v. 53, n. 4, p. 657-680, 1997.
    • (1997) Drugs , vol.53 , Issue.4 , pp. 657-680
    • Perry, C.M.1    Faulds, D.2
  • 39
    • 0030199966 scopus 로고    scopus 로고
    • Clinical toxicity of antiretroviral nucleoside analogs
    • STYRT, B. A.; PIAZZA-HEPP, T. D.; CHIKAMI, G. K. Clinical toxicity of antiretroviral nucleoside analogs. Antiv. Res., v. 31, p. 121-135, 1996.
    • (1996) Antiv. Res. , vol.31 , pp. 121-135
    • Styrt, B.A.1    Piazza-Hepp, T.D.2    Chikami, G.K.3
  • 40
    • 0035853626 scopus 로고    scopus 로고
    • Determination of serum levels of thirteen human immunodeficiency virus-suppressing drugs by high-performance liquid chromatography
    • SIMON, V. A.; THIAM, M. D.; LIPFORD, L. C. Determination of serum levels of thirteen human immunodeficiency virus-suppressing drugs by high-performance liquid chromatography. J. Chromatogr. A., v. 913, p. 447-453, 2001.
    • (2001) J. Chromatogr. A , vol.913 , pp. 447-453
    • Simon, V.A.1    Thiam, M.D.2    Lipford, L.C.3
  • 41
    • 0029869720 scopus 로고    scopus 로고
    • Interation between lamivudine (3TC) and other nucleoside analogues for intracellular phosphorilation
    • VEAL, G. J.; HOGGARD, P. G.; BARRY, M. G.; KHOO, S.; BACL, D. J. Interation between lamivudine (3TC) and other nucleoside analogues for intracellular phosphorilation. AIDS., v. 10, n. 5, p. 546-548, 1996.
    • (1996) AIDS , vol.10 , Issue.5 , pp. 546-548
    • Veal, G.J.1    Hoggard, P.G.2    Barry, M.G.3    Khoo, S.4    Bacl, D.J.5
  • 42
    • 0029591968 scopus 로고
    • Metabolism of zidovudine
    • VEAL, G. J.; BACK, J. D. Metabolism of zidovudine. Gen. Pharmacol., v. 26, n. 7, p. 1469-1475, 1995.
    • (1995) Gen. Pharmacol. , vol.26 , Issue.7 , pp. 1469-1475
    • Veal, G.J.1    Back, J.D.2
  • 43
    • 0030912073 scopus 로고    scopus 로고
    • Rapid quantitation of (-)-2'-deoxy-3'-thiacytidine in human serum by high-performance liquid chromatography with ultraviolet detection
    • ZHOU, X. L.; SOMMADOSSI, J. P. Rapid quantitation of (-)-2'-deoxy-3'- thiacytidine in human serum by high-performance liquid chromatography with ultraviolet detection. J. Chromatogr. B., v. 691, p. 417-424, 1997.
    • (1997) J. Chromatogr. B , vol.691 , pp. 417-424
    • Zhou, X.L.1    Sommadossi, J.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.