Simultaneous quantitation of the 5′-triphosphate metabolites of zidovudine, lamivudine, and stavudine in peripheral mononuclear blood cells of HIV infected patients by high-performance liquid chromatography tandem mass spectrometry

Journal of the American Society for Mass Spectrometry

Volumn 11, Issue 12, 2000, Pages 1134-1143

  Moore, Jeff D ^a   Valette, Gilles ^a   Darque, Albert ^a   Zhou, Xiao Jian ^a   Sommadossi, Jean Pierre ^a,b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; CELLS; ENZYMES; EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; ORGANIC COMPOUNDS; VIRUSES;

MONONUCLEAR BLOOD CELLS;

METABOLITES;

3' AZIDO 2',3' DIDEOXYURIDINE; DRUG METABOLITE; LAMIVUDINE; LAMIVUDINE 5' TRIPHOSPHATE; NUCLEOSIDE; NUCLEOSIDE TRIPHOSPHATE; STAVUDINE; STAVUDINE 5' TRIPHOSPHATE; UNCLASSIFIED DRUG; ZIDOVUDINE; ZIDOVUDINE 5' TRIPHOSPHATE;

MASS SPECTROMETRY;

ACCURACY; ANALYTIC METHOD; ARTICLE; CALIBRATION; CASE REPORT; CELL LEVEL; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; ION EXCHANGE; MONONUCLEAR CELL; PATIENT; PHYSICAL PHENOMENA; QUADRUPOLE; QUANTITATIVE ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOLID PHASE EXTRACTION; STANDARD; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS; VOLUNTEER;

ANTI-HIV AGENTS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTIDINE TRIPHOSPHATE; DRUG THERAPY, COMBINATION; HIV INFECTIONS; HUMANS; LAMIVUDINE; MASS SPECTROMETRY; MONOCYTES; REFERENCE STANDARDS; SENSITIVITY AND SPECIFICITY; STAVUDINE; THYMINE NUCLEOTIDES; ZIDOVUDINE;

EID: 0034488247     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1044-0305(00)00178-1     Document Type: Article

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