메뉴 건너뛰기




Volumn 134, Issue 4, 2004, Pages 324-331

Vaccine engineering improved by hybrid technology

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; ANTIGEN; EPITOPE; VACCINE;

EID: 4043133762     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000079535     Document Type: Review
Times cited : (36)

References (82)
  • 2
    • 0031757985 scopus 로고    scopus 로고
    • Vaccine requirements for sustained cellular immunity to an intracellular parasitic infection
    • Gurunathan S, Prussin C, Sacks DL, Seder RA: Vaccine requirements for sustained cellular immunity to an intracellular parasitic infection. Nat Med 1998;4:1409-1415.
    • (1998) Nat Med , vol.4 , pp. 1409-1415
    • Gurunathan, S.1    Prussin, C.2    Sacks, D.L.3    Seder, R.A.4
  • 3
    • 0035525357 scopus 로고    scopus 로고
    • Towards a blood-stage vaccine for malaria: Are we following all the leads?
    • Good MF: Towards a blood-stage vaccine for malaria: Are we following all the leads? Nat Rev Immunol 2001;1:117-125.
    • (2001) Nat Rev Immunol , vol.1 , pp. 117-125
    • Good, M.F.1
  • 4
    • 0035495579 scopus 로고    scopus 로고
    • How can immunology contribute to the control of tuberculosis?
    • Kaufmann SHE: How can immunology contribute to the control of tuberculosis? Nat Rev Immunol 2001;1:20-30.
    • (2001) Nat Rev Immunol , vol.1 , pp. 20-30
    • Kaufmann, S.H.E.1
  • 5
    • 0036547263 scopus 로고    scopus 로고
    • New hope for an AIDS vaccine
    • Robinson HL: New hope for an AIDS vaccine. Nat Rev Immunol 2002;2:239-250.
    • (2002) Nat Rev Immunol , vol.2 , pp. 239-250
    • Robinson, H.L.1
  • 6
    • 0036719574 scopus 로고    scopus 로고
    • Antibodies, viruses and vaccines
    • Burton DR: Antibodies, viruses and vaccines. Nat Rev Immunol 2002;2:706-713.
    • (2002) Nat Rev Immunol , vol.2 , pp. 706-713
    • Burton, D.R.1
  • 8
    • 0035523169 scopus 로고    scopus 로고
    • Vaccine safety-vaccine benefits: Science and public's perception
    • Wilson CB, Marcuse EK: Vaccine safety-vaccine benefits: Science and public's perception. Nat Rev Immunol 2001;1:160-165.
    • (2001) Nat Rev Immunol , vol.1 , pp. 160-165
    • Wilson, C.B.1    Marcuse, E.K.2
  • 9
    • 0035751961 scopus 로고    scopus 로고
    • Strategies for designing and optimizing new generation vaccines
    • Berzofsky JA, Ahlers JD, Belyakov IM: Strategies for designing and optimizing new generation vaccines. Nat Rev Immunol 2001;1:209-219.
    • (2001) Nat Rev Immunol , vol.1 , pp. 209-219
    • Berzofsky, J.A.1    Ahlers, J.D.2    Belyakov, I.M.3
  • 10
    • 84984761803 scopus 로고    scopus 로고
    • Identification of tumor-associated T-cell epitopes for vaccine development
    • Stevanovic S: Identification of tumor-associated T-cell epitopes for vaccine development. Nat Rev Cancer 2002;2:1-7.
    • (2002) Nat Rev Cancer , vol.2 , pp. 1-7
    • Stevanovic, S.1
  • 12
    • 0141720783 scopus 로고    scopus 로고
    • Cancer vaccines: Between the idea and the reality
    • Finn OJ: Cancer vaccines: Between the idea and the reality. Nat Rev Immunol 2003;3:630-641.
    • (2003) Nat Rev Immunol , vol.3 , pp. 630-641
    • Finn, O.J.1
  • 13
    • 0345827680 scopus 로고    scopus 로고
    • Prevention of cervical cancer through papillomavirus vaccination
    • Frazer IH: Prevention of cervical cancer through papillomavirus vaccination. Nat Rev Immunol 2004;4:46-55.
    • (2004) Nat Rev Immunol , vol.4 , pp. 46-55
    • Frazer, I.H.1
  • 16
    • 0031784380 scopus 로고    scopus 로고
    • Immunologic changes associated with allergen immunotherapy
    • Durham SR, Till SJ: Immunologic changes associated with allergen immunotherapy. J Allergy Clin Immunol 1998;102:157-164.
    • (1998) J Allergy Clin Immunol , vol.102 , pp. 157-164
    • Durham, S.R.1    Till, S.J.2
  • 17
    • 0031817107 scopus 로고    scopus 로고
    • WHO position paper. Allergen immunotherapy: Therapeutic vaccines for allergic diseases
    • Bousquet J, Lockey R, Malling HJ: WHO position paper. Allergen immunotherapy: Therapeutic vaccines for allergic diseases. Allergy 1998;53:1-42.
    • (1998) Allergy , vol.53 , pp. 1-42
    • Bousquet, J.1    Lockey, R.2    Malling, H.J.3
  • 18
    • 0037031090 scopus 로고    scopus 로고
    • Effect of Tcell peptides derived from Fel d 1 on allergic reactions and cytokine production in patients sensitive to cats: A randomised controlled trial
    • Oldfield WL, Larche M, Kay AB: Effect of Tcell peptides derived from Fel d 1 on allergic reactions and cytokine production in patients sensitive to cats: A randomised controlled trial. Lancet 2002;360:47-53.
    • (2002) Lancet , vol.360 , pp. 47-53
    • Oldfield, W.L.1    Larche, M.2    Kay, A.B.3
  • 19
    • 0036598404 scopus 로고    scopus 로고
    • The future of antigen-specific immunotherapy of allergy
    • Valenta R: The future of antigen-specific immunotherapy of allergy. Nat Rev Immunol 2002;2:446-453.
    • (2002) Nat Rev Immunol , vol.2 , pp. 446-453
    • Valenta, R.1
  • 21
    • 0037167684 scopus 로고    scopus 로고
    • Mucosal administration of heat shock protein-65 decreases atherosclerosis and inflammation in aortic arch of low-density lipoprotein receptor-deficient mice
    • Maron R, Sukhova G, Faria AM, Hoffmann E, Mach F, Libby P, Weiner HL: Mucosal administration of heat shock protein-65 decreases atherosclerosis and inflammation in aortic arch of low-density lipoprotein receptor-deficient mice. Circulation 2002;106:1708-1715.
    • (2002) Circulation , vol.106 , pp. 1708-1715
    • Maron, R.1    Sukhova, G.2    Faria, A.M.3    Hoffmann, E.4    Mach, F.5    Libby, P.6    Weiner, H.L.7
  • 22
    • 0030987548 scopus 로고    scopus 로고
    • Copolymer 1 induces T cells of the T helper type 2 that cross-react with myelin basic protein and suppress experimental autoimmune encephalomyelitis
    • USA
    • Aharoni R, Teitelbaum D, Sela M, Arnon R: Copolymer 1 induces T cells of the T helper type 2 that cross-react with myelin basic protein and suppress experimental autoimmune encephalomyelitis. Proc Natl Acad Sci USA 1997;94:10821-10826.
    • (1997) Proc Natl Acad Sci , vol.94 , pp. 10821-10826
    • Aharoni, R.1    Teitelbaum, D.2    Sela, M.3    Arnon, R.4
  • 24
    • 0345643410 scopus 로고    scopus 로고
    • Production of recombinant subunit vaccines: Protein immunogens, live delivery systems and nucleic acid vaccines
    • Liljeqvist S, Stahl S: Production of recombinant subunit vaccines: Protein immunogens, live delivery systems and nucleic acid vaccines. J Biotechnol 1999;73:1-33.
    • (1999) J Biotechnol , vol.73 , pp. 1-33
    • Liljeqvist, S.1    Stahl, S.2
  • 25
    • 15444353066 scopus 로고    scopus 로고
    • Immunization with purified natural and recombinant allergens induces mouse IgG1 antibodies that recognize similar epitopes as human IgE and inhibit the human IgE-allergen interaction and allergen-induced basophil degranulation
    • Vrtala S, Ball T, Spitzauer S, Pandjaitan B, Suphioglu C, Knox B, Sperr WR, Valent P, Kraft D, Valenta R: Immunization with purified natural and recombinant allergens induces mouse IgG1 antibodies that recognize similar epitopes as human IgE and inhibit the human IgE-allergen interaction and allergen-induced basophil degranulation. J Immunol 1998;160:6137-6144.
    • (1998) J Immunol , vol.160 , pp. 6137-6144
    • Vrtala, S.1    Ball, T.2    Spitzauer, S.3    Pandjaitan, B.4    Suphioglu, C.5    Knox, B.6    Sperr, W.R.7    Valent, P.8    Kraft, D.9    Valenta, R.10
  • 26
    • 0031158980 scopus 로고    scopus 로고
    • Correlation of tolerogenicity of a viral antigen with its immunogenicity
    • Bachmann MF, Fehr T, Freer G, Hengartner H, Zinkernagel RM: Correlation of tolerogenicity of a viral antigen with its immunogenicity. J Immunol 1997;158:5106-5111.
    • (1997) J Immunol , vol.158 , pp. 5106-5111
    • Bachmann, M.F.1    Fehr, T.2    Freer, G.3    Hengartner, H.4    Zinkernagel, R.M.5
  • 27
    • 0001399408 scopus 로고    scopus 로고
    • Recombinant allergens with reduced allergenicity but retaining immunogenicity of the natural allergens: Hybrids of yellow jacket and paper wasp venom allergen antigen 5s
    • King TP, Jim SY, Monsalve RI, Kagey-Sobotka A, Lichtenstein LM, Spangfort MD: Recombinant allergens with reduced allergenicity but retaining immunogenicity of the natural allergens: Hybrids of yellow jacket and paper wasp venom allergen antigen 5s. J Immunol 2001;166:6057-6065.
    • (2001) J Immunol , vol.166 , pp. 6057-6065
    • King, T.P.1    Jim, S.Y.2    Monsalve, R.I.3    Kagey-Sobotka, A.4    Lichtenstein, L.M.5    Spangfort, M.D.6
  • 29
    • 0036676925 scopus 로고    scopus 로고
    • Combination vaccines for the treatment of grass pollen allergy consisting of genetically engineered hybrid molecules with increased immunogenicity
    • Linhart B, Jahn-Schmid B, Verdino P, Keller W, Ebner C, Kraft D, Valenta R: Combination vaccines for the treatment of grass pollen allergy consisting of genetically engineered hybrid molecules with increased immunogenicity. FASEB J 2002;16:1301-1303.
    • (2002) FASEB J , vol.16 , pp. 1301-1303
    • Linhart, B.1    Jahn-Schmid, B.2    Verdino, P.3    Keller, W.4    Ebner, C.5    Kraft, D.6    Valenta, R.7
  • 32
    • 0033604543 scopus 로고    scopus 로고
    • Signalling through the high-affinity IgE receptor Fc epsilon RI
    • Turner H, Kinet JP: Signalling through the high-affinity IgE receptor Fc epsilon RI. Nature 1999;402:24-30.
    • (1999) Nature , vol.402 , pp. 24-30
    • Turner, H.1    Kinet, J.P.2
  • 34
    • 0030965584 scopus 로고    scopus 로고
    • IgE-mediated allergen presentation via Fc epsilon RI on antigen-presenting cells
    • Stingl G, Maurer D: IgE-mediated allergen presentation via Fc epsilon RI on antigen-presenting cells. Int Arch Allergy Immunol 1997;113:24-29.
    • (1997) Int Arch Allergy Immunol , vol.113 , pp. 24-29
    • Stingl, G.1    Maurer, D.2
  • 35
    • 0030299848 scopus 로고    scopus 로고
    • Fc epsilon RI on antigen-presenting cells
    • Bieber T: Fc epsilon RI on antigen-presenting cells. Curr Opin Immunol 1996;8:773-777.
    • (1996) Curr Opin Immunol , vol.8 , pp. 773-777
    • Bieber, T.1
  • 36
    • 0141958643 scopus 로고    scopus 로고
    • Renaissance of the blocking antibody concept in type I allergy
    • Flicker S, Valenta R: Renaissance of the blocking antibody concept in type I allergy. Int Arch Allergy Immunol 2003;132:13-24.
    • (2003) Int Arch Allergy Immunol , vol.132 , pp. 13-24
    • Flicker, S.1    Valenta, R.2
  • 37
    • 0043264799 scopus 로고    scopus 로고
    • Allergen-specific immunotherapy with a monophosphoryl lipid A-adjuvanted vaccine: Reduced seasonally boosted immunoglobulin e production and inhibition of basophil histamine release by therapy-induced blocking antibodies
    • Mothes N, Heinzkill M, Drachenberg KJ, Sperr WR, Krauth MT, Majlesi Y, Semper H, Valent P, Niederberger V, Kraft D, Valenta R: Allergen-specific immunotherapy with a monophosphoryl lipid A-adjuvanted vaccine: Reduced seasonally boosted immunoglobulin E production and inhibition of basophil histamine release by therapy-induced blocking antibodies. Clin Exp Allergy 2003;33:1-11.
    • (2003) Clin Exp Allergy , vol.33 , pp. 1-11
    • Mothes, N.1    Heinzkill, M.2    Drachenberg, K.J.3    Sperr, W.R.4    Krauth, M.T.5    Majlesi, Y.6    Semper, H.7    Valent, P.8    Niederberger, V.9    Kraft, D.10    Valenta, R.11
  • 39
    • 0005629635 scopus 로고    scopus 로고
    • The recombinant allergen-based concept of component-resolved diagnostics and immunotherapy (CRD and CRIT)
    • Valenta R, Lidholm J, Niederberger V, Hayek B, Kraft D, Gronlund H: The recombinant allergen-based concept of component-resolved diagnostics and immunotherapy (CRD and CRIT). Clin Exp Allergy 1999;29:896-904.
    • (1999) Clin Exp Allergy , vol.29 , pp. 896-904
    • Valenta, R.1    Lidholm, J.2    Niederberger, V.3    Hayek, B.4    Kraft, D.5    Gronlund, H.6
  • 41
    • 0030458495 scopus 로고    scopus 로고
    • False-positive skin prick test responses to commercially available dog dander extracts caused by contamination with house dust mite (Dermatophagoides pteronyssinus) allergens
    • van der Veen MJ, Mulder M, Witteman AM, van Ree R, Aalberse RC, Jansen HM, van der Zee JS: False-positive skin prick test responses to commercially available dog dander extracts caused by contamination with house dust mite (Dermatophagoides pteronyssinus) allergens. J Allergy Clin Immunol 1996;98:1028-1034.
    • (1996) J Allergy Clin Immunol , vol.98 , pp. 1028-1034
    • Van Der Veen, M.J.1    Mulder, M.2    Witteman, A.M.3    Van Ree, R.4    Aalberse, R.C.5    Jansen, H.M.6    Van Der Zee, J.S.7
  • 43
    • 0035109363 scopus 로고    scopus 로고
    • Recombinant allergen molecules: Tools to study effector cell activation
    • Valenta R, Kraft D: Recombinant allergen molecules: Tools to study effector cell activation. Immunol Rev 2001;179:119-127.
    • (2001) Immunol Rev , vol.179 , pp. 119-127
    • Valenta, R.1    Kraft, D.2
  • 44
    • 0036888370 scopus 로고    scopus 로고
    • From allergen structure to new forms of allergen-specific immunotherapy
    • Valenta R, Kraft D: From allergen structure to new forms of allergen-specific immunotherapy. Curr Opin Immunol 2002;14:718-727.
    • (2002) Curr Opin Immunol , vol.14 , pp. 718-727
    • Valenta, R.1    Kraft, D.2
  • 45
    • 0020619604 scopus 로고
    • Isolation and immunochemical characterization of the major allergen of birch pollen (Betula verrucosa)
    • Ipsen H, Lowenstein H: Isolation and immunochemical characterization of the major allergen of birch pollen (Betula verrucosa). J Allergy Clin Immunol 1983;72:150-159.
    • (1983) J Allergy Clin Immunol , vol.72 , pp. 150-159
    • Ipsen, H.1    Lowenstein, H.2
  • 46
    • 0021213550 scopus 로고
    • Cat allergen 1: Biochemical, antigenic, and allergenic properties
    • Leitermann K, Ohman JL: Cat allergen 1: Biochemical, antigenic, and allergenic properties. J Allergy Clin Immunol 1984;74:147-153.
    • (1984) J Allergy Clin Immunol , vol.74 , pp. 147-153
    • Leitermann, K.1    Ohman, J.L.2
  • 47
    • 0024443144 scopus 로고
    • The gene coding for the major birch pollen allergen Bet v 1, is highly homologous to a pea disease resistance response gene
    • Breiteneder H, Pettenburger K, Bito A, Valenta R, Kraft D, Rumpold H, Scheiner O, Breitenbach M: The gene coding for the major birch pollen allergen Bet v 1, is highly homologous to a pea disease resistance response gene. EMBO J 1989;8:1935-1938.
    • (1989) EMBO J , vol.8 , pp. 1935-1938
    • Breiteneder, H.1    Pettenburger, K.2    Bito, A.3    Valenta, R.4    Kraft, D.5    Rumpold, H.6    Scheiner, O.7    Breitenbach, M.8
  • 50
    • 0031794759 scopus 로고    scopus 로고
    • Recombinant birch pollen allergens (rBet v 1 and rBet v 2) contain most of the IgE epitopes present in birch, alder, hornbeam, hazel, and oak pollen: A quantitative IgE inhibition study with sera from different populations
    • Niederberger V, Pauli G, Gronlund H, Froschl R, Rumpold H, Kraft D, Valenta R, Spitzauer S: Recombinant birch pollen allergens (rBet v 1 and rBet v 2) contain most of the IgE epitopes present in birch, alder, hornbeam, hazel, and oak pollen: A quantitative IgE inhibition study with sera from different populations. J Allergy Clin Immunol 1998;102:579-591.
    • (1998) J Allergy Clin Immunol , vol.102 , pp. 579-591
    • Niederberger, V.1    Pauli, G.2    Gronlund, H.3    Froschl, R.4    Rumpold, H.5    Kraft, D.6    Valenta, R.7    Spitzauer, S.8
  • 52
    • 0024255816 scopus 로고
    • Monoclonal antibodies to the major feline allergen Fel d I. Serologic and biologic activity of affinity-purified Fel d I and of Fel d I depleted extract
    • de Groot H, van Swieten P, van Leeuwen J, Lind P, Aalberse RC: Monoclonal antibodies to the major feline allergen Fel d I. Serologic and biologic activity of affinity-purified Fel d I and of Fel d I depleted extract. J Allergy Clin Immunol 1988;82:778-786.
    • (1988) J Allergy Clin Immunol , vol.82 , pp. 778-786
    • De Groot, H.1    Van Swieten, P.2    Van Leeuwen, J.3    Lind, P.4    Aalberse, R.C.5
  • 57
    • 0033759739 scopus 로고    scopus 로고
    • Structure and biology of stinging insect venom allergens
    • King TP, Spangfort MD: Structure and biology of stinging insect venom allergens. Int Arch Allergy Immunol 2000;123:99-106.
    • (2000) Int Arch Allergy Immunol , vol.123 , pp. 99-106
    • King, T.P.1    Spangfort, M.D.2
  • 58
    • 0033928258 scopus 로고    scopus 로고
    • Molecular and biochemical classification of plant-derived food allergens
    • Breiteneder H, Ebner C: Molecular and biochemical classification of plant-derived food allergens. Int Arch Allergy Immunol 2000;106:27-36.
    • (2000) Int Arch Allergy Immunol , vol.106 , pp. 27-36
    • Breiteneder, H.1    Ebner, C.2
  • 62
    • 0037229842 scopus 로고    scopus 로고
    • Characteristics and immunobiology of grass pollen allergens
    • Andersson K, Lidholm J: Characteristics and immunobiology of grass pollen allergens. Int Arch Allergy Immunol 2003;130:87-107.
    • (2003) Int Arch Allergy Immunol , vol.130 , pp. 87-107
    • Andersson, K.1    Lidholm, J.2
  • 65
    • 0036095437 scopus 로고    scopus 로고
    • Recombinant marker allergens: Diagnostic gatekeepers for the treatment of allergy
    • Kazemi-Shirazi L, et al: Recombinant marker allergens: Diagnostic gatekeepers for the treatment of allergy. Int Arch Allergy Immunol 2002;127:259-268.
    • (2002) Int Arch Allergy Immunol , vol.127 , pp. 259-268
    • Kazemi-Shirazi, L.1
  • 66
    • 4544343180 scopus 로고    scopus 로고
    • The transition from a botanical to a molecular classification in tree pollen allergy: Implications for diagnosis and therapy
    • in press
    • Mothes N, Horak F, Valenta R: The transition from a botanical to a molecular classification in tree pollen allergy: Implications for diagnosis and therapy. Int Arch Allergy Immunol, in press.
    • Int Arch Allergy Immunol
    • Mothes, N.1    Horak, F.2    Valenta, R.3
  • 69
    • 0031924659 scopus 로고    scopus 로고
    • IgE antibodies to recombinant allergens (Phl p 1, Phl p 2, Phl p 5, and Bet v 2) account for a high percentage of grass pollen-specific IgE
    • Niederberger V, Laffer S, Fröschl R, Kraft D, Rumpold H, Kapiotis S, Valenta R, Spitzauer S: IgE antibodies to recombinant allergens (Phl p 1, Phl p 2, Phl p 5, and Bet v 2) account for a high percentage of grass pollen-specific IgE. J Allergy Clin Immunol 1998;101:258-264.
    • (1998) J Allergy Clin Immunol , vol.101 , pp. 258-264
    • Niederberger, V.1    Laffer, S.2    Fröschl, R.3    Kraft, D.4    Rumpold, H.5    Kapiotis, S.6    Valenta, R.7    Spitzauer, S.8
  • 70
    • 0013898788 scopus 로고
    • Studies on the effect of the carrier molecule on antihapten antibody synthesis. II. Carrier specificity of the anti-2,4-dinitrophenyl-poly-l-lysine antibodies
    • Paul WE, Siskind GW, Benacerraf B: Studies on the effect of the carrier molecule on antihapten antibody synthesis. II. Carrier specificity of the anti-2,4-dinitrophenyl-poly-l-lysine antibodies. J Exp Med 1966;123:689-705.
    • (1966) J Exp Med , vol.123 , pp. 689-705
    • Paul, W.E.1    Siskind, G.W.2    Benacerraf, B.3
  • 71
    • 0014829537 scopus 로고
    • Carrier function in anti-hapten immune responses. II. Specific properties of carrier cells capable of enhancing anti-hapten antibody responses
    • Paul WE, Katz DH, Goidl EA, Benacerraf B: Carrier function in anti-hapten immune responses. II. Specific properties of carrier cells capable of enhancing anti-hapten antibody responses. J Exp Med 1970;132:283-299.
    • (1970) J Exp Med , vol.132 , pp. 283-299
    • Paul, W.E.1    Katz, D.H.2    Goidl, E.A.3    Benacerraf, B.4
  • 72
    • 0014829780 scopus 로고
    • Carrier function in anti-hapten immune responses. I. Enhancement of primary and secondary anti-hapten antibody responses by carrier preimmunization
    • Katz DH, Paul WE, Goidl EA, Benacerraf B: Carrier function in anti-hapten immune responses. I. Enhancement of primary and secondary anti-hapten antibody responses by carrier preimmunization. J Exp Med 1970;132:261-282.
    • (1970) J Exp Med , vol.132 , pp. 261-282
    • Katz, D.H.1    Paul, W.E.2    Goidl, E.A.3    Benacerraf, B.4
  • 73
    • 0015038383 scopus 로고
    • The carrier effect in the secondary response to hapten-protein conjugates. V. Use of anti-lymphocyte serum to deplete animals of helper cells
    • Mitchison NA: The carrier effect in the secondary response to hapten-protein conjugates. V. Use of anti-lymphocyte serum to deplete animals of helper cells. Eur J Immunol 1971;1:68-75.
    • (1971) Eur J Immunol , vol.1 , pp. 68-75
    • Mitchison, N.A.1
  • 74
    • 0015038983 scopus 로고
    • The carrier effect in the secondary response to hapten-protein conjugates. 3. The anatomical distribution of helper cells and antibody-formingcell-precursors
    • Boak JL, Mitchison NA, Pattisson PH: The carrier effect in the secondary response to hapten-protein conjugates. 3. The anatomical distribution of helper cells and antibody-formingcell-precursors. Eur J Immunol 1971;1:63-65.
    • (1971) Eur J Immunol , vol.1 , pp. 63-65
    • Boak, J.L.1    Mitchison, N.A.2    Pattisson, P.H.3
  • 75
    • 0016738688 scopus 로고
    • Induction of T lymphocyte responses to a small molecular weight antigen. III. T-T cell interactions to determinants linked together: Suppression vs. enhancement
    • Bullock WW, Katz DH, Benacerraf B: Induction of T lymphocyte responses to a small molecular weight antigen. III. T-T cell interactions to determinants linked together: Suppression vs. enhancement. J Exp Med 1975;142:275-287.
    • (1975) J Exp Med , vol.142 , pp. 275-287
    • Bullock, W.W.1    Katz, D.H.2    Benacerraf, B.3
  • 76
    • 0034544450 scopus 로고    scopus 로고
    • T cell epitope-containing hypoallergenic recombinant fragments of the major birch pollen allergen, Bet v 1, induce blocking antibodies
    • Vrtala S, Akdis CA, Budak F, Akdis M, Blaser K, Kraft D, Valenta R: T cell epitope-containing hypoallergenic recombinant fragments of the major birch pollen allergen, Bet v 1, induce blocking antibodies. J Immunol 2000;165:6653-6659.
    • (2000) J Immunol , vol.165 , pp. 6653-6659
    • Vrtala, S.1    Akdis, C.A.2    Budak, F.3    Akdis, M.4    Blaser, K.5    Kraft, D.6    Valenta, R.7
  • 78
    • 0032783475 scopus 로고    scopus 로고
    • B cell epitopes of the major timothy grass pollen allergen, Phl p 1, revealed by gene fragmentation as candidates for immunotherapy
    • Ball T, et al: B cell epitopes of the major timothy grass pollen allergen, Phl p 1, revealed by gene fragmentation as candidates for immunotherapy. FASEB J 1999;13:1277-1290.
    • (1999) FASEB J , vol.13 , pp. 1277-1290
    • Ball, T.1
  • 79
    • 0035464780 scopus 로고    scopus 로고
    • Nonanaphylactic synthetic peptides derived from B cell epitopes of the major grass pollen allergen, Phl p 1, for allergy vaccination
    • Focke M, Mahler V, Ball T, Sperr WR, Majlesi Y, Valent P Kraft D, Valenta R: Nonanaphylactic synthetic peptides derived from B cell epitopes of the major grass pollen allergen, Phl p 1, for allergy vaccination. FASEB J 2001;15:2042-2044.
    • (2001) FASEB J , vol.15 , pp. 2042-2044
    • Focke, M.1    Mahler, V.2    Ball, T.3    Sperr, W.R.4    Majlesi, Y.5    Valent, P.6    Kraft, D.7    Valenta, R.8
  • 81
    • 0035577475 scopus 로고    scopus 로고
    • Immunization with an interferon-gamma- gp 120 fusion protein induces enhanced immune responses to human immunodeficiency virus gp 120
    • McCormick AL, Thomas MS, Heath AW: Immunization with an interferon-gamma- gp 120 fusion protein induces enhanced immune responses to human immunodeficiency virus gp 120. J Infect Dis 2001;184:1423-1430.
    • (2001) J Infect Dis , vol.184 , pp. 1423-1430
    • McCormick, A.L.1    Thomas, M.S.2    Heath, A.W.3
  • 82
    • 0035863822 scopus 로고    scopus 로고
    • Vaccination with allergen-IL-18 fusion DNA protects against, and reverses established, airway hyperreactivity in a murine asthma model
    • Maecker HT, Hansen G, Walter DM, De-Kruyff RH, Levy S, Umetsu DT: Vaccination with allergen-IL-18 fusion DNA protects against, and reverses established, airway hyperreactivity in a murine asthma model. J Immunol 2001;166:959-965.
    • (2001) J Immunol , vol.166 , pp. 959-965
    • Maecker, H.T.1    Hansen, G.2    Walter, D.M.3    De-Kruyff, R.H.4    Levy, S.5    Umetsu, D.T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.