Immunity to latent viral infection: Many skirmishes but few fatalities

Trends in Immunology

Volumn 25, Issue 5, 2004, Pages 230-234

  Khanna, Kamal M ^a   Lepisto, Andrew J ^a   Hendricks, Robert L ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; VIRUS VACCINE;

GENE EXPRESSION; HERPES; HERPES SIMPLEX VIRUS 1; HUMAN; IMMUNE SYSTEM; IMMUNITY; IMMUNOLOGICAL TECHNIQUE; LATENT PERIOD; LATENT VIRUS INFECTION; RECURRENT DISEASE; REVIEW; SENSORY NERVE CELL; T LYMPHOCYTE;

EID: 4043126793     PISSN: 14714906     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.it.2004.02.010     Document Type: Article

References (38)

1. Liesegang T.J. Herpes simplex virus epidemiology and ocular importance. Cornea. 20:2001;1-13.
2. Stevens J.G., et al. RNA complementary to a herpesvirus α gene mRNA is prominent in latently infected neurons. Science. 235:1987;1056-1059.
3. Feldman L.T., et al. Spontaneous molecular reactivation of herpes simplex virus type 1 latency in mice. Proc. Natl. Acad. Sci. U. S. A. 99:2002;978-983.
4. Chen S.H., et al. Neither LAT nor open reading frame p mutations increase expression of spliced or intron-containing ICP0 transcripts in mouse ganglia latently infected with herpes simplex virus. J. Virol. 76:2002;4764-4772.
5. Kramer M.F., Coen D.M. Quantification of transcripts from the ICP4 and thymidine kinase genes in mouse ganglia latently infected with herpes simplex virus. J. Virol. 69:1995;1389-1399.
6. Chen S.H., et al. A viral function represses accumulation of transcripts from productive-cycle genes in mouse ganglia latently infected with herpes simplex virus. J. Virol. 71:1997;5878-5884.
7. Sawtell N.M. Quantitative analysis of herpes simplex virus reactivation in vivo demonstrates that reactivation in the nervous system is not inhibited at early times postinoculation. J. Virol. 77:2003;4127-4138.
8. + T cells can block herpes simplex virus type 1 (HSV-1) reactivation from latency in sensory neurons. J. Exp. Med. 191:2000;1459-1466.
9. Gebhardt B.M., Hill J.M. Cellular neuroimmunologic responses to ocular herpes simplex virus infection. J. Neuroimmunol. 28:1990;227-236.
10. Liu T., et al. Inflammatory infiltration of the trigeminal ganglion after herpes simplex virus type 1 corneal infection. J. Virol. 70:1996;264-271.
11. Theil D., et al. Latent herpesvirus infection in human trigeminal ganglia causes chronic immune response. Am. J. Pathol. 163:2003;2179-2184.
12. Carbone F.R., Speck P.G. Hide and seek: the immunology of HSV persistence. Immunity. 18:2003;583-584.
13. Halford W.P., et al. Persistent cytokine expression in trigeminal ganglion latently infected with herpes simplex virus type 1. J. Immunol. 157:1996;3542-3549.
14. Halford W.P., et al. Acyclovir blocks cytokine gene expression in trigeminal ganglia latently infected with herpes simplex virus type 1. Virology. 238:1997;53-63.
15. Cantin E.M., et al. Gamma interferon expression during acute and latent nervous system infection by herpes simplex virus type 1. J. Virol. 69:1995;4898-4905.
16. + T cells. Nature. 401:1999;76-79.
17. + T cells are activated and retained in latently infected sensory ganglia and can regulate viral latency. Immunity. 18:2003;593-603.
18. Kagi D., et al. Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity. Science. 265:1994;528-530.
19. Kojima H., et al. Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes. Immunity. 1:1994;357-364.
20. Guidotti L.G., et al. Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes. Immunity. 4:1996;25-36.
21. + cell anti-HIV factor (CAF). Trends Immunol. 24:2003;628-632.
22. Claoue C., et al. Neural spread of herpes simplex virus to the eye of the mouse: microbiological aspects and effect on the blink reflex. Eye. 2:1988;318-323.
23. Cantin E., et al. Role for γ interferon in control of herpes simplex virus type 1 reactivation. J. Virol. 73:1999;3418-3423.
24. Minami M., et al. Role of IFN-γ and tumor necrosis factor-α in herpes simplex virus type 1 infection. J. Interferon Cytokine Res. 22:2002;671-676.
25. Liu T., et al. Gamma interferon can prevent herpes simplex virus type 1 reactivation from latency in sensory neurons. J. Virol. 75:2001;11178-11184.
26. Halford W.P., Schaffer P.A. ICP0 is required for efficient reactivation of herpes simplex virus type1 from neuronal latency. J. Virol. 75:2001;3240-3249.
27. Harle P., et al. The immediate-early protein, ICP0, is essential for the resistance of herpes simplex virus to interferon-alpha/beta. Virology. 293:2002;295-304.
28. Valitutti S., et al. Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy. J. Exp. Med. 183:1996;1917-1921.
29. Mosmann T.R., Fong T.A.T. Specific assays for cytokine production by T cells. J. Immunol. Methods. 116:1989;151-158.
30. 2+-independent T cell-mediated cytotoxicity. J. Exp. Med. 177:1993;195-200.
31. + TC1 cells: loss of IL-2 synthesis and autonomous proliferation but retention of cytotoxicity and synthesis of other cytokines. J. Exp. Med. 182:1995;1505-1515.
32. Pereira R.A., et al. Upregulation of class I major histocompatibility complex gene expression in primary sensory neurons, satellite cells, and Schwann cells of mice in response to acute but not latent herpes simplex virus infection in vivo. J. Exp. Med. 180:1994;841-850.
33. Pereira R.A., Simmons A. Cell surface expression of H2 antigens on primary sensory neurons in response to acute but not latent herpes simplex virus infection in vivo. J. Virol. 73:1999;6484-6489.
34. + T cells. J. Virol. 77:2003;2445-2451.
35. Jerome K.R., et al. Herpes simplex virus inhibits apoptosis through the action of two genes Us5 and Us3. J. Virol. 73:1999;8950-8957.
36. Cartier A., et al. The herpes simplex virus-1 Us3 protein kinase blocks CD8 T cell lysis by preventing the cleavage of Bid by granzyme B. Cell Death Differ. 10:2003;1320-1328.
37. Kaech S.M., et al. Molecular and functional profiling of memory CD8 T cell differentiation. Cell. 111:2002;837-851.
38. Tomazin R., et al. Stable binding of the herpes simplex virus ICP47 protein to the peptide binding site of TAP. EMBO J. 15:1996;3256-3266.