Latent Herpesvirus Infection in Human Trigeminal Ganglia Causes Chronic Immune Response

American Journal of Pathology

Volumn 163, Issue 6, 2003, Pages 2179-2184

  Theil, Diethilde ^a   Derfuss, Tobias ^a,b,c   Paripovic, Igor ^a   Herberger, Simone ^a   Meinl, Edgar ^b,c   Schueler, Olaf ^a   Strupp, Michael ^a   Arbusow, Viktor ^a   Brandt, Thomas ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b MAX PLANCK INSTITUTE OF NEUROBIOLOGY   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD8 ANTIGEN; CHEMOKINE; CHLORDANE; CYTOKINE; GAMMA INTERFERON; RANTES; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; CELLULAR IMMUNITY; CHILD; CHRONIC INFLAMMATION; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; HERPES SIMPLEX VIRUS 1; HERPES VIRUS INFECTION; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; INFANT; LYMPHOCYTIC INFILTRATION; MACROPHAGE; MALE; NEWBORN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRIGEMINUS GANGLION; VARICELLA ZOSTER VIRUS; VIRUS LATENCY;

EID: 0344413030     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)63575-4     Document Type: Article

References (34)

1. Croen DK, Ostrove JM, Dragovic LJ, Smialek JE, Straus SE: Latent herpes simplex virus in human trigeminal ganglia: detection of an immediate early gene 'antisense' transcript by in situ hybridisation. N Engl J Med 1987, 317:142-1432
2. Furuta Y, Takasu T, Sato KC, Fukuda S, Inuyama Y, Nagashima K: Latent herpes virus type 1 in human geniculate ganglia. Acta Neuropathol (Berl) 1992, 84:39-44
3. Theil D, Arbusow V, Derfuss T, Strupp M, Pfeiffer M, Mascolo A, Brandt T: Prevalence of HSV-1 LAT in human trigeminal, geniculate, and vestibular ganglia and its implication for cranial nerve syndromes. Brain Pathol 2001, 11:408-413
4. Simmons A, Tscharke D, Speck P: The role of immune mechanisms in control of herpes simplex virus infection of the peripheral nervous system. Curr Top Microbiol Immunol 1992, 179:31-56
5. Mester JC, Rouse BT: The mouse model and understanding immunity to herpes simplex virus. Rev Infect Dis 1991, 13:935-945
6. Dyck PJ, Giannini C, Lais A: Pathological alterations of nerves. Peripheral Neuropathy Edited by PJ Dyck, PK Thomas, JW Griffin, PA Low, JF Poduslo. Philadelphia, WB Saunders Co., 1993, pp 517-559
7. Hickey WF: Basic principles of immunological surveillance of the normal central nervous system. Glia 2001, 36:118-124
8. Allt G, Lawrenson JG: The blood-nerve barrier: enzymes, transporters and receptors: a comparison with the blood-brain barrier. Brain Res Bull 2000, 52:1-12
9. Cantin EM, Hinton DR, Chen J, Openshaw H: Gamma interferon expression during acute and latent nervous system infection by herpes simplex virus type 1. J Virol 1995, 69:4898-4905
10. Shimeld C, Whiteland JL, Nicholls SM, Grinfeld E, Easty DL, Gao H, Hill T: Immune cell infiltration and persistence in the mouse trigeminal ganglion after infection of the cornea with herpes simplex virus type 1. J Neuroimmunol 1995, 61:7-16
11. Halford WP, Gebhardt BM, Carr DJ: Persistent cytokine expression in trigeminal ganglion latently infected with herpes simplex virus type 1. J Immunol 1996, 157:3542-3549
12. Liu T, Tang Q, Hendricks RL: Inflammatory infiltration of the trigeminal ganglion after herpes simplex virus type 1 corneal infection. J Virol 1996, 70:264-271
13. Chen S-H, Graber DA, Schaffer PA, Knipe DM, Coen DM: Persistent elevated expression of cytokine transcripts in ganglia latently infected with herpes simplex virus in the absence of ganglionic replication or reactivation. Virology 2000, 278:207-216
14. Ellison AR, Yang L, Voytek C, Margolis T: Establishment of latent herpes simplex virus type 1 infection in resistant, sensitive, and immunodeficient mouse strains. Virology 2000, 268:17-28
15. Kennedy PGE, Grinfeld E, Bell EJ: Varicella-zoster virus gene expression in latently infected and explanted human ganglia. J Virol 2000, 74:11893-11898
16. Naoe M, Marumoto R, Ishizaki Y, Ogawa Y, Nakagami Y, Yoshida H: Correlation between major histocompatibility complex class I molecules and CD8+ T lymphocytes in prostate, and quantification of CD8 and interferon-γ mRNA in prostate tissue specimens. BJU Int 2002, 90:748-753
17. Brink N, Szamel M, Young AR, Wittern KP, Bergemann J: Comparative quantification of IL-1β, IL-10, IL-10r, TNFα, and IL-7 mRNA levels in UV-irradiated human skin in vivo. Inflamm Res 2000, 49:290-296
18. Yin JL, Shackel NA, Zekry A, McGuinness PH, Richards C, Putten KV, McCaughan GW, Eris JM, Bishop GA: Real-time reverse transcriptase-polymerase chain reaction (RT-PCR) for measurement of cytokine and growth factor mRNA expression with fluorogenic probes or SYBR green I. Immunol Cell Biol 2001, 79:213-221
19. Kramer MF, Chen S-H, Knipe DM, Coen DM: Accumulation of viral transcripts and DNA during establishment of latency by herpes simplex virus. J Virol 1998, 72:1177-1185
20. Feldman LT, Ellison AR, Voytek CC, Yang L, Krause P, Margolis TP: Spontaneous molecular reactivation of herpes simplex virus type 1 latency in mice. Proc Natl Acad Sci USA 2002, 99:978-983
21. Neumann H, Cavalie A, Jenne DE, Wekerle H: Induction of MHC class I genes in neurons. Science 1995, 269:549-552
22. Perng GC, Maguen B, Jin L, Mott KR, Kurylo J, BenMohamed L, Yukht A, Osorio N, Nesburn AB, Henderson G, Inman M, Jones C, Wechsler SL: A novel herpes simplex virus type 1 transcript (AL-RNA) antisense to the 5′ end of the latency-associated transcript produces a protein in infected rabbits. J Virol 2002, 76:8003-8010
23. Heath WR, Carbone FR: Cross-presentation in viral immunity and self-tolerance. Nat Rev Immunol 2001, 1:126-134
24. Theil D, Derfuss T, Strupp M, Gilden DH, Arbusow V, Brandt T: Cranial nerve palsies: herpes simplex virus type 1 and varicella-zoster virus latency. Ann Neurol 2002, 51:273
25. Lungu O, Panagiotidis CA, Annunziato PW, Gershon AA, Silverstein SJ: Aberrant intracellular localization of varicella-zoster virus regulatory proteins during latency. Proc Natl Acad Sci USA 1998, 95:7080-7085
26. Mahalingam R, Wellish M, Cohrs R, Debrus S, Piette J, Rentier B, Gilden DH: Expression of protein encoded by varicella-zoster virus open reading frame 63 in latently infected human ganglionic neurons. Proc Natl Acad Sci USA 1996, 93:2122-2124
27. Guidotti LG, Chisari FV: Noncytolytic control of viral infections by the innate and adaptive immune response. Annu Rev Immunol 2001, 19:65-91
28. Feduchi E, Alonso MA, Carrasco L: Human gamma interferon and tumor necrosis factor exert a synergistic blockade on the replication of herpes simplex virus. J Virol 1989, 63:1354-1359
29. Paludan SR, Mogensen SC: Virus-cell interactions regulating induction of tumor necrosis factor a production in macrophages infected with herpes simplex virus. J Virol 2001, 75:10170
30. Liu T, Khanna KM, Chen XP, Fink DJ, Hendricks LR: CD8+ T cells can block herpes simplex virus type 1 (HSV-1) reactivation from latency in sensory neurons. J Exp Med 2000, 191:1459-1466
31. Liu T, Khanna KM, Carriere BN, Hendricks RL: Gamma interferon can prevent herpes simplex virus type 1 reactivation from latency in sensory neurons. J Virol 2001, 75:11178-11184
32. Melchjorsen J, Pedersen FS, Mogensen SC, Paludan SR: Herpes simplex virus selectively induces expression of the CC chemokine RANTES/CCL5 in macrophages through a mechanism dependent on PKR and ICP0. J Virol 2002, 76:2780-2788
33. Lokensgard JR, Hu S, Sheng W, van Oijen M, Cox D, Cheeran MC, Peterson PK: Robust expression of TNF-α, IL-1β, RANTES, and IP-10 by human microglial cells during nonproductive infection with herpes simplex virus. J Neurovirol 2001, 7:208-219
34. Khanna KM, Bonneau RH, Kinchington PR, Hendricks RL: Herpes simplex virus-specific memory CD8+ T cells are selectively activated and retained in latently infected sensory ganglia. Immunity 2003, 18:593-603