Ezetimibe potently inhibits cholesterol absorption but does not affect acute hepatic or intestinal cholesterol synthesis in rats

British Journal of Pharmacology

Volumn 138, Issue 8, 2003, Pages 1459-1464

  Van Heek, Margaret ^a   Farley, Constance ^a   Compton, Douglas S ^a   Hoos, Lizbeth M ^a   Smith Torhan, April ^a   Davis, Harry R ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Cholesterol absorption inhibitor; Cholesteryl ester; Ezetimibe; Hepatic cholesterol; Intestinal cholesterol; Lymph; Rat

Indexed keywords

1,4 BIS(4 METHOXYPHENYL) 3 (3 PHENYLPROPYL) 2 AZETIDINONE; CARBON 14; CHOLESTEROL; CHOLESTEROL ESTER; EZETIMIBE; KETOCONAZOLE; MEVALONIC ACID;

ABSORPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL LIVER LEVEL; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; FEMALE; HYPERCHOLESTEROLEMIA; INHIBITION KINETICS; INTESTINE; INTESTINE CELL; ISOTOPE LABELING; LIVER; MALE; MESENTERY LYMPH NODE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTICHOLESTEREMIC AGENTS; AZETIDINES; CHOLESTEROL; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPERCHOLESTEROLEMIA; INTESTINAL ABSORPTION; LIVER; MALE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0038291655     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705187     Document Type: Article

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