메뉴 건너뛰기




Volumn 15, Issue 4, 2004, Pages 393-398

CETP gene variation: Relation to lipid parameters and cardiovascular risk

Author keywords

CETP; Cholesteryl ester transfer protein; Coronary artery disease; Genetics; HDL

Indexed keywords

AMINO ACID; CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LOW DENSITY LIPOPROTEIN; PRAVASTATIN;

EID: 4043096347     PISSN: 09579672     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mol.0000137226.54278.60     Document Type: Review
Times cited : (60)

References (77)
  • 1
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
    • Scandinavian Simvastatin Survival Study investigators. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet 1994; 344:1383-1389.
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 2
    • 0037031061 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of cholesterol lowering with Simvastatin in 20,536 high-risk individuals: A randomised placebo-controlled trial
    • Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol lowering with Simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet 2002; 360:7-22.
    • (2002) Lancet , vol.360 , pp. 7-22
  • 3
    • 0028883828 scopus 로고
    • Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia
    • West of Scotland Coronary Prevention Study Group
    • Shepherd J, Cobbe SM, Ford I, et al. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group. N Engl J Med 1995; 333:1301-1307.
    • (1995) N Engl J Med , vol.333 , pp. 1301-1307
    • Shepherd, J.1    Cobbe, S.M.2    Ford, I.3
  • 4
    • 0017384270 scopus 로고
    • High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study
    • Gordon T, Castelli WP, Hjortland MC, et al. High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study. Am J Med 1977; 62:707-714.
    • (1977) Am J Med , vol.62 , pp. 707-714
    • Gordon, T.1    Castelli, W.P.2    Hjortland, M.C.3
  • 5
    • 0017614773 scopus 로고
    • The Tromso heart-study. High-density lipoprotein and coronary heart-disease: A prospective cass-control study
    • Miller NE, Thelle DS, Forde OH, et al. The Tromso heart-study. High-density lipoprotein and coronary heart-disease: a prospective cass-control study. Lancet 1977; 1:965-968.
    • (1977) Lancet , vol.1 , pp. 965-968
    • Miller, N.E.1    Thelle, D.S.2    Forde, O.H.3
  • 6
    • 0032510639 scopus 로고    scopus 로고
    • Prediction of coronary heart disease using risk factor categories
    • Wilson PW, D'Agostino RB, Levy D, et al. Prediction of coronary heart disease using risk factor categories. Circulation 1998; 97:1837-1847.
    • (1998) Circulation , vol.97 , pp. 1837-1847
    • Wilson, P.W.1    D'Agostino, R.B.2    Levy, D.3
  • 7
    • 14344284525 scopus 로고    scopus 로고
    • Low high-density lipoprotein cholesterol as a risk factor in coronary heart disease: A working group report
    • Gotto AM Jr. Low high-density lipoprotein cholesterol as a risk factor in coronary heart disease: a working group report. Circulation 2001; 103:2213-2218.
    • (2001) Circulation , vol.103 , pp. 2213-2218
    • Gotto Jr., A.M.1
  • 8
    • 0037035459 scopus 로고    scopus 로고
    • Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: A randomized phase II doss-response study
    • De Grooth GJ, Kuivenhoven JA, Stalenhoef AF, et al. Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: a randomized phase II doss-response study. Circulation 2002; 105:2159-2165.
    • (2002) Circulation , vol.105 , pp. 2159-2165
    • De Grooth, G.J.1    Kuivenhoven, J.A.2    Stalenhoef, A.F.3
  • 9
    • 12144287356 scopus 로고    scopus 로고
    • Raising high-density lipoprotein in humans through inhibition of cholesteryl ester transfer protein: An initial multidose study of torcetrapib
    • Clark RW, Sutfin TA, Ruggeri RB, et al. Raising high-density lipoprotein in humans through inhibition of cholesteryl ester transfer protein: an initial multidose study of torcetrapib. Arterioscler Thromb Vasc Biol 2004; 24:490-497.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 490-497
    • Clark, R.W.1    Sutfin, T.A.2    Ruggeri, R.B.3
  • 10
    • 0027325516 scopus 로고
    • Severe atherosclerosis in transgenic mice expressing simian cholesteryl ester transfer protein
    • Marotti KR, Castle CK, Boyle TP, et al. Severe atherosclerosis in transgenic mice expressing simian cholesteryl ester transfer protein. Nature 1993; 364:73-75.
    • (1993) Nature , vol.364 , pp. 73-75
    • Marotti, K.R.1    Castle, C.K.2    Boyle, T.P.3
  • 11
    • 0032917975 scopus 로고    scopus 로고
    • Increased atherosclerosis in ApoE and LDL receptor gene knock-out mice as a result of human cholesteryl ester transfer protein transgene expression
    • Plump AS, Masucci-Magoulas L, Bruce C, et al. Increased atherosclerosis in ApoE and LDL receptor gene knock-out mice as a result of human cholesteryl ester transfer protein transgene expression. Arterioscler Thromb Vasc Biol 1999; 19:1105-1110.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 1105-1110
    • Plump, A.S.1    Masucci-Magoulas, L.2    Bruce, C.3
  • 12
    • 0028784246 scopus 로고
    • Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene
    • Hayek T, Masucci-Magoulas L, Jiang X, et al. Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene. J Clin Invest 1995; 96:2071-2074.
    • (1995) J Clin Invest , vol.96 , pp. 2071-2074
    • Hayek, T.1    Masucci-Magoulas, L.2    Jiang, X.3
  • 13
    • 10244232759 scopus 로고    scopus 로고
    • A novel nonsense mutation (G181X) in the human cholesteryl ester transfer protein gene in Japanese hyperalphalipoproteinemic subjects
    • Arai T, Yamashita S, Sakai N, et al. A novel nonsense mutation (G181X) in the human cholesteryl ester transfer protein gene in Japanese hyperalphalipoproteinemic subjects. J Lipid Res 1996; 37:2145-2150.
    • (1996) J Lipid Res , vol.37 , pp. 2145-2150
    • Arai, T.1    Yamashita, S.2    Sakai, N.3
  • 14
    • 0036120909 scopus 로고    scopus 로고
    • A novel mutation in the intron 1 splice donor site of the cholesterol ester transfer protein (CETP) gene as a cause of hyperalphalipoproteinemia
    • Jap TS, Wu YC, Tso YC, et al. A novel mutation in the intron 1 splice donor site of the cholesterol ester transfer protein (CETP) gene as a cause of hyperalphalipoproteinemia. Metabolism 2002; 51:394-397.
    • (2002) Metabolism , vol.51 , pp. 394-397
    • Jap, T.S.1    Wu, Y.C.2    Tso, Y.C.3
  • 15
    • 0001445065 scopus 로고
    • Identification of mutations in the cholesterol ester transfer protein in Europeans with elevated high density lipoprotein cholesterol
    • Funke H, Wiebusch H, Fuer L, et al. Identification of mutations in the cholesterol ester transfer protein in Europeans with elevated high density lipoprotein cholesterol. Circulation 1994; 90:1-124.
    • (1994) Circulation , vol.90 , pp. 1-124
    • Funke, H.1    Wiebusch, H.2    Fuer, L.3
  • 16
    • 0031457897 scopus 로고    scopus 로고
    • Deficiency of cholesteryl ester transfer protein. Description of the molecular defect and the dissociation of cholesteryl ester and triglyceride transport in plasma
    • Ritsch A, Drexel H, Amann FW, et al. Deficiency of cholesteryl ester transfer protein. Description of the molecular defect and the dissociation of cholesteryl ester and triglyceride transport in plasma. Arterioscler Thromb Vasc Biol 1997; 17:3433-3441.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 3433-3441
    • Ritsch, A.1    Drexel, H.2    Amann, F.W.3
  • 17
    • 0031910644 scopus 로고    scopus 로고
    • Human plasma CETP deficiency: Identification of a novel mutation in exon 9 of the CETP gene in a Caucasian subject from North America
    • Teh EM, Dolphin PJ, Breckenridge WC, et al. Human plasma CETP deficiency: identification of a novel mutation in exon 9 of the CETP gene in a Caucasian subject from North America. J Lipid Res 1998; 39:442-456.
    • (1998) J Lipid Res , vol.39 , pp. 442-456
    • Teh, E.M.1    Dolphin, P.J.2    Breckenridge, W.C.3
  • 18
    • 0030984690 scopus 로고    scopus 로고
    • The cholesteryl ester transfer protein (CETP) locus as a candidate gene in abdominal aortic aneurysm
    • Ramsbottom D, O'Neill A, Sexton DM, et al. The cholesteryl ester transfer protein (CETP) locus as a candidate gene in abdominal aortic aneurysm. Clin Genet 1997; 51:241-245.
    • (1997) Clin Genet , vol.51 , pp. 241-245
    • Ramsbottom, D.1    O'Neill, A.2    Sexton, D.M.3
  • 19
    • 0027227681 scopus 로고
    • Cholesteryl ester transfer protein deficiency caused by a nonsense mutation detected in the patient's macrophage mRNA
    • Gotoda T, Kinoshita M, Shimano H, et al. Cholesteryl ester transfer protein deficiency caused by a nonsense mutation detected in the patient's macrophage mRNA. Biochem Biophys Res Commun 1993; 194:519-524.
    • (1993) Biochem Biophys Res Commun , vol.194 , pp. 519-524
    • Gotoda, T.1    Kinoshita, M.2    Shimano, H.3
  • 20
    • 0029859668 scopus 로고    scopus 로고
    • Exon 10 skipping caused by intron 10 splice donor site mutation in cholesteryl ester transfer protein gene results in abnormal downstream splice site selection
    • Sakai N, Santamarina-Fojo S, Yamashita S, et al. Exon 10 skipping caused by intron 10 splice donor site mutation in cholesteryl ester transfer protein gene results in abnormal downstream splice site selection. J Lipid Res 1996; 37:2065-2073.
    • (1996) J Lipid Res , vol.37 , pp. 2065-2073
    • Sakai, N.1    Santamarina-Fojo, S.2    Yamashita, S.3
  • 21
    • 0024415898 scopus 로고
    • Molecular basis of lipid transfer deficiency in a family with increased high-density lipoproteins
    • Brown ML, Inazu A, Hesler CB, et al. Molecular basis of lipid transfer deficiency in a family with increased high-density lipoproteins. Nature 1989; 342:448-451.
    • (1989) Nature , vol.342 , pp. 448-451
    • Brown, M.L.1    Inazu, A.2    Hesler, C.B.3
  • 22
    • 0028135441 scopus 로고
    • Genetic cholesteryl ester transfer protein deficiency caused by two prevalent mutations as a major determinant of increased levels of high density lipoprotein cholesterol
    • Inazu A, Jiang XC, Haraki T, et al. Genetic cholesteryl ester transfer protein deficiency caused by two prevalent mutations as a major determinant of increased levels of high density lipoprotein cholesterol. J Clin Invest 1994; 94:1872-1882.
    • (1994) J Clin Invest , vol.94 , pp. 1872-1882
    • Inazu, A.1    Jiang, X.C.2    Haraki, T.3
  • 23
    • 0142010558 scopus 로고    scopus 로고
    • Natural genetic variation as a tool in understanding the role of CETP in lipid levels and disease
    • Boekholdt SM, Thompson JF. Natural genetic variation as a tool in understanding the role of CETP in lipid levels and disease. J Lipid Res 2003; 44:1080-1093. This meta-analysis provides large-scale evidence that both the Taq1B and I405V variants are significantly associated with CETP activity and HDL-c levels.
    • (2003) J Lipid Res , vol.44 , pp. 1080-1093
    • Boekholdt, S.M.1    Thompson, J.F.2
  • 24
    • 0022346576 scopus 로고
    • Deficiency of serum cholesteryl-ester transfer activity in patients with familial hyperalphalipoproteinaemia
    • Koizumi J, Mabuchi H, Yoshimura A, et al. Deficiency of serum cholesteryl-ester transfer activity in patients with familial hyperalphalipoproteinaemia. Atherosclerosis 1985; 58:175-186.
    • (1985) Atherosclerosis , vol.58 , pp. 175-186
    • Koizumi, J.1    Mabuchi, H.2    Yoshimura, A.3
  • 25
    • 0023881202 scopus 로고
    • Small polydisperse low density lipoproteins in familial hyperalphalipoproteinemia with complete deficiency of cholesteryl ester transfer activity
    • Yamashita S, Matsuzawa Y, Okazaki M, et al. Small polydisperse low density lipoproteins in familial hyperalphalipoproteinemia with complete deficiency of cholesteryl ester transfer activity. Atherosclerosis 1988; 70:7-12.
    • (1988) Atherosclerosis , vol.70 , pp. 7-12
    • Yamashita, S.1    Matsuzawa, Y.2    Okazaki, M.3
  • 26
    • 0029948968 scopus 로고    scopus 로고
    • Increased coronary heart disease in Japanese-American men with mutation in the cholesteryl-ester transfer protein gene despite increased HDL levels
    • Zhong S, Sharp DS, Grove JS, et al. Increased coronary heart disease in Japanese-American men with mutation in the cholesteryl-ester transfer protein gene despite increased HDL levels. J Clin Invest 1996; 97:2917-2923.
    • (1996) J Clin Invest , vol.97 , pp. 2917-2923
    • Zhong, S.1    Sharp, D.S.2    Grove, J.S.3
  • 27
    • 0025104275 scopus 로고
    • Increased high-density lipoprotein levels caused by a common cholesteryl-ester transfer protein gene mutation
    • Inazu AM, Brown ML, Hesler CB, et al. Increased high-density lipoprotein levels caused by a common cholesteryl-ester transfer protein gene mutation. N Engl J Med 1990; 323:1234-1238.
    • (1990) N Engl J Med , vol.323 , pp. 1234-1238
    • Inazu, A.M.1    Brown, M.L.2    Hesler, C.B.3
  • 28
    • 0028575740 scopus 로고
    • Cholesteryl ester transfer protein gene: Two common mutations and their effect on plasma high-density lipoprotein cholesterol content
    • Akita H, Chiba H, Tschuchihashi K, et al. Cholesteryl ester transfer protein gene: two common mutations and their effect on plasma high-density lipoprotein cholesterol content. J Clin Endocrinol Metab 1994; 79:1615-1618.
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 1615-1618
    • Akita, H.1    Chiba, H.2    Tschuchihashi, K.3
  • 29
    • 0033800003 scopus 로고    scopus 로고
    • Particle size analysis of high density lipoproteins in patients with genetic cholesteryl ester transfer protein deficiency
    • Arai T, Tsukada T, Murase T, et al. Particle size analysis of high density lipoproteins in patients with genetic cholesteryl ester transfer protein deficiency. Clin Chim Acta 2000; 301:103-117.
    • (2000) Clin Chim Acta , vol.301 , pp. 103-117
    • Arai, T.1    Tsukada, T.2    Murase, T.3
  • 30
    • 14444277710 scopus 로고    scopus 로고
    • Quantitative and compositional changes in high density lipoprotein subclasses in patients with various genotypes of cholesteryl ester transfer protein deficiency
    • Chiba H, Akita H, Tsuchihashi K, et al. Quantitative and compositional changes in high density lipoprotein subclasses in patients with various genotypes of cholesteryl ester transfer protein deficiency. J Lipid Res 1997; 38:1204-1216.
    • (1997) J Lipid Res , vol.38 , pp. 1204-1216
    • Chiba, H.1    Akita, H.2    Tsuchihashi, K.3
  • 31
    • 0035718873 scopus 로고    scopus 로고
    • Point mutation (-69 G→A) in the promoter region of cholesteryl ester transfer protein gene in Japanese hyperalphalipoproteinemic subjects
    • Nagano M, Yamashita S, Hirano K, et al. Point mutation (-69 G→A) in the promoter region of cholesteryl ester transfer protein gene in Japanese hyperalphalipoproteinemic subjects. Arterioscler Thromb Vasc Biol 2001; 21:985-990.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 985-990
    • Nagano, M.1    Yamashita, S.2    Hirano, K.3
  • 32
    • 0035026352 scopus 로고    scopus 로고
    • Effects of hepatic lipase gene promoter nucleotide variations on serum HDL cholesterol concentration in the general Japanese population
    • Inazu A, Nishimura Y, Tereda Y, et al. Effects of hepatic lipase gene promoter nucleotide variations on serum HDL cholesterol concentration in the general Japanese population. J Hum Genet 2001; 46:172-177.
    • (2001) J Hum Genet , vol.46 , pp. 172-177
    • Inazu, A.1    Nishimura, Y.2    Tereda, Y.3
  • 33
    • 0037212396 scopus 로고    scopus 로고
    • Prevalence and phenotypic spectrum of cholesteryl ester transfer protein gene mutations in Japanese hyperalphalipoproteinemia
    • Maruyama T, Sakai N, Ishigami M, et al. Prevalence and phenotypic spectrum of cholesteryl ester transfer protein gene mutations in Japanese hyperalphalipoproteinemia. Atherosclerosis 2003; 166:177-185.
    • (2003) Atherosclerosis , vol.166 , pp. 177-185
    • Maruyama, T.1    Sakai, N.2    Ishigami, M.3
  • 34
    • 0035047564 scopus 로고    scopus 로고
    • Identification of the intron 14 splicing defect of the cholesteryl ester transfer protein gene in Hong Kong Chinese
    • Ma YQ, Thomas GN, Critchley JA, et al. Identification of the intron 14 splicing defect of the cholesteryl ester transfer protein gene in Hong Kong Chinese. Clin Genet 2001; 59:287-289.
    • (2001) Clin Genet , vol.59 , pp. 287-289
    • Ma, Y.Q.1    Thomas, G.N.2    Critchley, J.A.3
  • 35
    • 0034813677 scopus 로고    scopus 로고
    • Effect of a common mutation (D442G) of the cholesteryl ester transfer protein gene on lipids and lipoproteins in children
    • Arashiro R, Katsuren K, Maung K, et al. Effect of a common mutation (D442G) of the cholesteryl ester transfer protein gene on lipids and lipoproteins in children. Pediatr Res 2001; 50:455-459.
    • (2001) Pediatr Res , vol.50 , pp. 455-459
    • Arashiro, R.1    Katsuren, K.2    Maung, K.3
  • 36
    • 0033050091 scopus 로고    scopus 로고
    • A common mutation of cholesteryl ester transfer protein gene in dialysis patients
    • Kimura H, Gejyo F, Suzuki S, et al. A common mutation of cholesteryl ester transfer protein gene in dialysis patients. Kidney Int 1999; 56:S186-S189.
    • (1999) Kidney Int , vol.56
    • Kimura, H.1    Gejyo, F.2    Suzuki, S.3
  • 37
    • 0028925455 scopus 로고
    • Frequency of exon 15 missense mutation (442D:G) in cholesteryl transfer protein gene in hyperalphalipoproteinemic Japanese subjects
    • Sakai N, Yamashita S, Hirano KI, et al. Frequency of exon 15 missense mutation (442D:G) in cholesteryl transfer protein gene in hyperalphalipoproteinemic Japanese subjects. Atherosclerosis 1995; 114:139-145.
    • (1995) Atherosclerosis , vol.114 , pp. 139-145
    • Sakai, N.1    Yamashita, S.2    Hirano, K.I.3
  • 38
    • 16944362351 scopus 로고    scopus 로고
    • Genetic cholesteryl ester transfer protein deficiency is extremely frequent in the Omagari area of Japan. Marked hyperalphalipoproteinemia caused by CETP gene mutation is not associated with longevity
    • Hirano K, Yamashita S, Nakajima N, et al. Genetic cholesteryl ester transfer protein deficiency is extremely frequent in the Omagari area of Japan. Marked hyperalphalipoproteinemia caused by CETP gene mutation is not associated with longevity. Arterioscler Thromb Vasc Biol 1997; 17:1053-1059.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 1053-1059
    • Hirano, K.1    Yamashita, S.2    Nakajima, N.3
  • 39
    • 0025104275 scopus 로고
    • Increased high-density lipoprotein levels caused by a common cholesteryl-ester transfer protein gene mutation
    • Inazu A, Brown ML, Hesler CB, et al. Increased high-density lipoprotein levels caused by a common cholesteryl-ester transfer protein gene mutation. N Engl J Med 1990; 323:1234-1238.
    • (1990) N Engl J Med , vol.323 , pp. 1234-1238
    • Inazu, A.1    Brown, M.L.2    Hesler, C.B.3
  • 40
    • 17444448251 scopus 로고    scopus 로고
    • A low prevalence of coronary heart disease among subjects with increased high-density lipoprotein cholesterol levels, including those with plasma cholesteryl ester transfer protein deficiency
    • Moriyama Y, Okamura T, Inazu A, et al. A low prevalence of coronary heart disease among subjects with increased high-density lipoprotein cholesterol levels, including those with plasma cholesteryl ester transfer protein deficiency. Prev Med 1998; 27:659-667.
    • (1998) Prev Med , vol.27 , pp. 659-667
    • Moriyama, Y.1    Okamura, T.2    Inazu, A.3
  • 41
    • 0035194258 scopus 로고    scopus 로고
    • Influence of CETP gene variation on plasma lipid levels and coronary heart disease: A survey in Taiwan
    • Wu JH, Lee YT, Hsu HC, et al. Influence of CETP gene variation on plasma lipid levels and coronary heart disease: a survey in Taiwan. Atherosclerosis 2001; 159:451-458.
    • (2001) Atherosclerosis , vol.159 , pp. 451-458
    • Wu, J.H.1    Lee, Y.T.2    Hsu, H.C.3
  • 42
    • 0036294244 scopus 로고    scopus 로고
    • CETP gene mutation (D442G) increases low-density lipoprotein particle size in patients with coronary heart disease
    • Wang JH, Qiang H, Chen D, et al. CETP gene mutation (D442G) increases low-density lipoprotein particle size in patients with coronary heart disease. Clin Chim Acta 2002; 322:85-90.
    • (2002) Clin Chim Acta , vol.322 , pp. 85-90
    • Wang, J.H.1    Qiang, H.2    Chen, D.3
  • 43
    • 0037327033 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein: A novel target for raising HDL and inhibiting atherosclerosis
    • Barter PJ, Brewer HB Jr, Chapman MJ, et al. Cholesteryl ester transfer protein: a novel target for raising HDL and inhibiting atherosclerosis. Arterioscler Thromb Vasc Biol 2003; 23:160-167.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 160-167
    • Barter, P.J.1    Brewer Jr., H.B.2    Chapman, M.J.3
  • 44
    • 4043177556 scopus 로고    scopus 로고
    • A novel intronic CETP mutation (In7+1) in Dutch subjects with hyperalphalipoproteinemia
    • Klerkx AH, Hovingh GK, Nooteboom I, et al. A novel intronic CETP mutation (In7+1) in Dutch subjects with hyperalphalipoproteinemia. Circulation 2003; 108 (Suppl):997.
    • (2003) Circulation , vol.108 , Issue.SUPPL. , pp. 997
    • Klerkx, A.H.1    Hovingh, G.K.2    Nooteboom, I.3
  • 45
    • 0035987264 scopus 로고    scopus 로고
    • Two novel missense mutations in the CETP gene in Japanese hyperalphaproteinemic subjects: High throughput assay by Invader assay
    • Nagano M, Yamashita S, Hirano K, et al. Two novel missense mutations in the CETP gene in Japanese hyperalphaproteinemic subjects: high throughput assay by Invader assay. J Lipid Res 2002; 43:1011-1018.
    • (2002) J Lipid Res , vol.43 , pp. 1011-1018
    • Nagano, M.1    Yamashita, S.2    Hirano, K.3
  • 46
    • 0032991552 scopus 로고    scopus 로고
    • Characterization of single-nucleotide polymorphisms in coding regions of human genes
    • Cargill M, Altshuler J, Ireland J, et al. Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nat Genet 1999; 22:231-238.
    • (1999) Nat Genet , vol.22 , pp. 231-238
    • Cargill, M.1    Altshuler, J.2    Ireland, J.3
  • 47
    • 0024563260 scopus 로고
    • An Stul RFLP at the human cholesteryl ester transfer protein (CETP) locus
    • Freeman DJ, Shepherd J, Packard CJ, et al. An Stul RFLP at the human cholesteryl ester transfer protein (CETP) locus. Nucleic Acids Res 1989; 17:2880.
    • (1989) Nucleic Acids Res , vol.17 , pp. 2880
    • Freeman, D.J.1    Shepherd, J.2    Packard, C.J.3
  • 48
    • 0025105228 scopus 로고
    • Organization of the human cholesteryl ester transfer protein gene
    • Agellon LB, Quinet EM, Gillette TG, et al. Organization of the human cholesteryl ester transfer protein gene. Biochemistry 1990; 29:1372-1376.
    • (1990) Biochemistry , vol.29 , pp. 1372-1376
    • Agellon, L.B.1    Quinet, E.M.2    Gillette, T.G.3
  • 49
    • 0027420629 scopus 로고
    • A missense mutation in the cholesteryl ester transfer protein gene with possible dominant effects on plasma high density lipoproteins
    • Takahashi K, Jiang XC, Sakai N, et al. A missense mutation in the cholesteryl ester transfer protein gene with possible dominant effects on plasma high density lipoproteins. J Clin Invest 1993; 92:2060-2064.
    • (1993) J Clin Invest , vol.92 , pp. 2060-2064
    • Takahashi, K.1    Jiang, X.C.2    Sakai, N.3
  • 50
    • 0033945005 scopus 로고    scopus 로고
    • Extensive association analysis between the CETP gene and coronary heart disease phenotypes reveals several putative functional polymorphisms and gene-environment interaction
    • Corbex M, Poirier O, Fumeron F, et al. Extensive association analysis between the CETP gene and coronary heart disease phenotypes reveals several putative functional polymorphisms and gene-environment interaction. Genet Epidemiol 2000; 19:64-80.
    • (2000) Genet Epidemiol , vol.19 , pp. 64-80
    • Corbex, M.1    Poirier, O.2    Fumeron, F.3
  • 51
    • 0034946988 scopus 로고    scopus 로고
    • Variation at the cholesteryl ester transfer protein gene in relation to plasma high density lipoproteins cholesterol levels and carotid intima-media thickness
    • Kakko S, Tamminen M, Paivansalo M, et al. Variation at the cholesteryl ester transfer protein gene in relation to plasma high density lipoproteins cholesterol levels and carotid intima-media thickness. Eur J Clin Invest 2001; 31:593-602.
    • (2001) Eur J Clin Invest , vol.31 , pp. 593-602
    • Kakko, S.1    Tamminen, M.2    Paivansalo, M.3
  • 52
    • 0037786655 scopus 로고    scopus 로고
    • Polymorphisms in the CETP gene and association with CETP mass and HDL levels
    • Thompson JF, Lira ME, Durham LK, et al. Polymorphisms in the CETP gene and association with CETP mass and HDL levels. Atherosclerosis 2003; 167:195-204.
    • (2003) Atherosclerosis , vol.167 , pp. 195-204
    • Thompson, J.F.1    Lira, M.E.2    Durham, L.K.3
  • 53
    • 0034283526 scopus 로고    scopus 로고
    • The contribution of candidate genes to the response of plasma lipids and lipoproteins to dietary challenge
    • Friedlander Y, Leitersdorf E, Vecsler R, et al. The contribution of candidate genes to the response of plasma lipids and lipoproteins to dietary challenge. Atherosclerosis 2000; 152:239-248.
    • (2000) Atherosclerosis , vol.152 , pp. 239-248
    • Friedlander, Y.1    Leitersdorf, E.2    Vecsler, R.3
  • 54
    • 0035200547 scopus 로고    scopus 로고
    • Genetic influences on the lipid metabolism trait variability within the Stanislas cohort
    • Pallaud C, Gueguen R, Sass C, et al. Genetic influences on the lipid metabolism trait variability within the Stanislas cohort. J Lipid Res 2001; 42:1879-1890.
    • (2001) J Lipid Res , vol.42 , pp. 1879-1890
    • Pallaud, C.1    Gueguen, R.2    Sass, C.3
  • 55
    • 0142089644 scopus 로고    scopus 로고
    • Analysis of the possible role of genetic factors in determination of the concentration of high-density-lipoprotein cholesterol in the Moscow population
    • Slominsky PA, Metelskaya VA, Miloserdova OV, et al. Analysis of the possible role of genetic factors in determination of the concentration of high-density-lipoprotein cholesterol in the Moscow population. Russ J Genet 2000; 36:1177-1180.
    • (2000) Russ J Genet , vol.36 , pp. 1177-1180
    • Slominsky, P.A.1    Metelskaya, V.A.2    Miloserdova, O.V.3
  • 56
    • 0033065475 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein gene effect on CETP activity and plasma high-density lipoprotein in European populations
    • Gudnason V, Kakko S, Nicaud V, et al. Cholesteryl ester transfer protein gene effect on CETP activity and plasma high-density lipoprotein in European populations. Eur J Clin Invest 1999; 29:116-128.
    • (1999) Eur J Clin Invest , vol.29 , pp. 116-128
    • Gudnason, V.1    Kakko, S.2    Nicaud, V.3
  • 57
    • 0034712706 scopus 로고    scopus 로고
    • Elevated HDL cholesterol is a risk factor for ischemic heart disease in white women when caused by a common mutation in the cholesteryl ester transfer protein
    • Agerholm-Larsen B, Nordestgaard BG, Steffensen R, et al. Elevated HDL cholesterol is a risk factor for ischemic heart disease in white women when caused by a common mutation in the cholesteryl ester transfer protein. Circulation 2000; 101:1907-1912.
    • (2000) Circulation , vol.101 , pp. 1907-1912
    • Agerholm-Larsen, B.1    Nordestgaard, B.G.2    Steffensen, R.3
  • 58
    • 0031942155 scopus 로고    scopus 로고
    • Relationship of HDL and coronary heart disease to a common amino acid polymorphism in the cholesteryl ester transfer protein in men with and without hypertriglyceridemia
    • Bruce C, Sharp DS, Tall AR. Relationship of HDL and coronary heart disease to a common amino acid polymorphism in the cholesteryl ester transfer protein in men with and without hypertriglyceridemia. J Lipid Res 1998; 39:1071-1078.
    • (1998) J Lipid Res , vol.39 , pp. 1071-1078
    • Bruce, C.1    Sharp, D.S.2    Tall, A.R.3
  • 59
    • 0142088521 scopus 로고    scopus 로고
    • Unique lipoprotein phenotype and genotype associated with exceptional longevity
    • Barzilai N, Atzmon G, Schechter C, et al. Unique lipoprotein phenotype and genotype associated with exceptional longevity. JAMA 2003; 290:2030-2040. Interesting study investigating determinants of longevity. The I405V variant has been previously related with lipoprotein levels, lipoprotein size, and CAD risk. This study confirms the relationship with lipoprotein size and, in addition, relates it to longevity.
    • (2003) JAMA , vol.290 , pp. 2030-2040
    • Barzilai, N.1    Atzmon, G.2    Schechter, C.3
  • 60
    • 0034061148 scopus 로고    scopus 로고
    • Association of cholesteryl ester transfer protein-Taq1B polymorphism with variations in lipoprotein subclasses and coronary heart disease risk. The Framingham study
    • Ordovas JM, Cupples A, Corella D, et al. Association of cholesteryl ester transfer protein-Taq1B polymorphism with variations in lipoprotein subclasses and coronary heart disease risk. The Framingham study. Arterioscler Thromb Vasc Biol 2000; 20:1323-1329.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1323-1329
    • Ordovas, J.M.1    Cupples, A.2    Corella, D.3
  • 61
    • 1842767407 scopus 로고    scopus 로고
    • The relationship between cholesteryl ester transfer protein levels and risk factor profile in patients with familial hypercholesterolemia
    • De Grooth GJ, Smilde TJ, van Wissen S, et al. The relationship between cholesteryl ester transfer protein levels and risk factor profile in patients with familial hypercholesterolemia. Atherosclerosis 2004; 173:260-267.
    • (2004) Atherosclerosis , vol.173 , pp. 260-267
    • De Grooth, G.J.1    Smilde, T.J.2    Van Wissen, S.3
  • 62
    • 0029740950 scopus 로고    scopus 로고
    • Association of small low-density lipoprotein particles with the incidence of coronary artery disease in men and women
    • Gardner CD, Fortmann SP, Krauss RM. Association of small low-density lipoprotein particles with the incidence of coronary artery disease in men and women. JAMA 1996; 276:875-881.
    • (1996) JAMA , vol.276 , pp. 875-881
    • Gardner, C.D.1    Fortmann, S.P.2    Krauss, R.M.3
  • 63
    • 0029741921 scopus 로고    scopus 로고
    • A prospective study of triglyceride level, low-density lipoprotein particle diameter, and risk of myocardial infarction
    • Stampfer MJ, Krauss RM, Ma J, et al. A prospective study of triglyceride level, low-density lipoprotein particle diameter, and risk of myocardial infarction. JAMA 1996; 276:882-888.
    • (1996) JAMA , vol.276 , pp. 882-888
    • Stampfer, M.J.1    Krauss, R.M.2    Ma, J.3
  • 64
    • 0024571215 scopus 로고
    • DNA polymorphism at the locus for human cholesteryl ester transfer protein (CETP) is associated with high density lipoprotein cholesterol and apolipoprotein levels
    • Kondo I, Berg K, Drayna D, et al. DNA polymorphism at the locus for human cholesteryl ester transfer protein (CETP) is associated with high density lipoprotein cholesterol and apolipoprotein levels. Clin Genet 1989; 35:49-56.
    • (1989) Clin Genet , vol.35 , pp. 49-56
    • Kondo, I.1    Berg, K.2    Drayna, D.3
  • 65
    • 0037439546 scopus 로고    scopus 로고
    • Haplotype analysis of the CETP gene: Not Taq1B, but the closely linked -629 C→A polymorphism and a novel promoter variant are independently associated with CETP concentration
    • Klerkx AH, Tanck MW, Kastelein JJ, et al. Haplotype analysis of the CETP gene: not Taq1B, but the closely linked -629 C→A polymorphism and a novel promoter variant are independently associated with CETP concentration. Hum Mol Genet 2003; 12:111-123. This extensive haplotype analysis of the CETP promoter region confirms a previous study which suggested that the Taq1B variant is not instrumental in determining CETP or HDL-c levels, but a marker for the -629 promoter variant.
    • (2003) Hum Mol Genet , vol.12 , pp. 111-123
    • Klerkx, A.H.1    Tanck, M.W.2    Kastelein, J.J.3
  • 66
    • 0034750404 scopus 로고    scopus 로고
    • The 629 > a polymorphism in the CETP gene does not explain the association of the Taq1B polymorphism with risk and age of Myocardial Infarction in Icelandic men
    • Eiriksdottir G, Bolla MK, Thorsson B, et al. The 629 > A polymorphism in the CETP gene does not explain the association of the Taq1B polymorphism with risk and age of Myocardial Infarction in Icelandic men. Atherosclerosis 2001; 159:187-192.
    • (2001) Atherosclerosis , vol.159 , pp. 187-192
    • Eiriksdottir, G.1    Bolla, M.K.2    Thorsson, B.3
  • 67
    • 0033951707 scopus 로고    scopus 로고
    • New functional promoter polymorphism, CETP/-629, in cholesteryl ester transfer protein (CETP) gene related to CETP mass and high density lipoprotein cholesterol levels: Role of Sp1/Sp3 in transcriptional regulation
    • Dachet C, Poirier O, Cambien F, et al. New functional promoter polymorphism, CETP/-629, in cholesteryl ester transfer protein (CETP) gene related to CETP mass and high density lipoprotein cholesterol levels: role of Sp1/Sp3 in transcriptional regulation. Arterioscler Thromb Vasc Biol 2000; 20:507-515.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 507-515
    • Dachet, C.1    Poirier, O.2    Cambien, F.3
  • 68
    • 0030021148 scopus 로고    scopus 로고
    • Sex difference in the regulation of plasma high density lipoprotein cholesterol by genetic and environmental factors
    • Kauma H, Savolainen M, Heikkila R, et al. Sex difference in the regulation of plasma high density lipoprotein cholesterol by genetic and environmental factors. Hum Genet 1996; 97:156-162.
    • (1996) Hum Genet , vol.97 , pp. 156-162
    • Kauma, H.1    Savolainen, M.2    Heikkila, R.3
  • 69
    • 0028177421 scopus 로고
    • Regulation of plasma HDL cholesterol and subfraction distribution by genetic and environmental factors. Associations between the Taq1B RFLP in the CETP gene and smoking and obesity
    • Freeman DJ, Griffin BA, Holmes AP, et al. Regulation of plasma HDL cholesterol and subfraction distribution by genetic and environmental factors. Associations between the Taq1B RFLP in the CETP gene and smoking and obesity. Arterioscler Thromb 1994; 14:336-344.
    • (1994) Arterioscler Thromb , vol.14 , pp. 336-344
    • Freeman, D.J.1    Griffin, B.A.2    Holmes, A.P.3
  • 70
    • 0032833701 scopus 로고    scopus 로고
    • Contribution of the cholesteryl ester transfer protein gene Taq1B polymorphism to the reduced plasma HDL-cholesterol levels found in abdominal obese men with the features of the insulin resistance syndrome
    • Vohl MC, Lamarche B, Pascot A, et al. Contribution of the cholesteryl ester transfer protein gene Taq1B polymorphism to the reduced plasma HDL-cholesterol levels found in abdominal obese men with the features of the insulin resistance syndrome Int J Obes Relat Metab Disord 1999; 23:918-925.
    • (1999) Int J Obes Relat Metab Disord , vol.23 , pp. 918-925
    • Vohl, M.C.1    Lamarche, B.2    Pascot, A.3
  • 71
    • 0029091283 scopus 로고
    • Alcohol intake modulates the effect of a polymorphism of the cholesteryl ester transfer protein gene on plasma high density lipoprotein and the risk of myocardial infarction
    • Fumeron F, Betoulle D, Luc G, et al. Alcohol intake modulates the effect of a polymorphism of the cholesteryl ester transfer protein gene on plasma high density lipoprotein and the risk of myocardial infarction. J Clin Invest 1995; 96:1664-1671.
    • (1995) J Clin Invest , vol.96 , pp. 1664-1671
    • Fumeron, F.1    Betoulle, D.2    Luc, G.3
  • 72
    • 0038121112 scopus 로고    scopus 로고
    • Common genetic variation of the cholesteryl ester transfer protein gene strongly predicts future cardiovascular death in patients with coronary artery disease
    • Blankenberg S, Rupprecht HJ, Bickel C, et al. Common genetic variation of the cholesteryl ester transfer protein gene strongly predicts future cardiovascular death in patients with coronary artery disease. J Am Coll Cardiol 2003; 41:1983-1989.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 1983-1989
    • Blankenberg, S.1    Rupprecht, H.J.2    Bickel, C.3
  • 73
    • 0032495541 scopus 로고    scopus 로고
    • The role of a common variant of the cholesteryl ester transfer protein gene in the progression of coronary atherosclerosis
    • Kuivenhoven JA, Jukema JW, Zwinderman AH, et al. The role of a common variant of the cholesteryl ester transfer protein gene in the progression of coronary atherosclerosis. N Engl J Med 1998; 338:86-93.
    • (1998) N Engl J Med , vol.338 , pp. 86-93
    • Kuivenhoven, J.A.1    Jukema, J.W.2    Zwinderman, A.H.3
  • 74
    • 0029050796 scopus 로고
    • Effects of lipid lowering by pravastatin on progression and regression of coronary artery disease in symptomatic men with normal to moderately elevated serum cholesterol levels: The regression growth evaluation statin study (REGRESS)
    • Jukema JW, Bruschke AVG, van Boven AJ, et al. Effects of lipid lowering by pravastatin on progression and regression of coronary artery disease in symptomatic men with normal to moderately elevated serum cholesterol levels: the regression growth evaluation statin study (REGRESS). Circulation 1995; 91:2528-2540.
    • (1995) Circulation , vol.91 , pp. 2528-2540
    • Jukema, J.W.1    Bruschke, A.V.G.2    Van Boven, A.J.3
  • 75
    • 1242314787 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein (CETP) concentration is associated with progression of atherosclerosis and response to pravastatin in men with coronary artery disease (REGRESS)
    • Klerkx AH, De Grooth GJ, Zwinderman AH, et al. Cholesteryl ester transfer protein (CETP) concentration is associated with progression of atherosclerosis and response to pravastatin in men with coronary artery disease (REGRESS). Eur J Clin Invest 2003; 34:21-28.
    • (2003) Eur J Clin Invest , vol.34 , pp. 21-28
    • Klerkx, A.H.1    De Grooth, G.J.2    Zwinderman, A.H.3
  • 76
    • 0142104870 scopus 로고    scopus 로고
    • A polymorphism of the cholesteryl ester transfer protein gene predicts cardiovascular events in non-smokers in the West of Scotland Coronary Prevention Study
    • Freeman DJ, Samani NJ, Wilson V, et al. A polymorphism of the cholesteryl ester transfer protein gene predicts cardiovascular events in non-smokers in the West of Scotland Coronary Prevention Study. Eur Heart J 2003; 24:1833-1842. Subanalysis of the West of Scotland coronary prevention study trial to investigate a potential clinically relevant pharmacogenetic interaction between the Taq1B variant and pravastatin therapy using the incidence of cardiovascular events as outcome.
    • (2003) Eur Heart J , vol.24 , pp. 1833-1842
    • Freeman, D.J.1    Samani, N.J.2    Wilson, V.3
  • 77
    • 10744219782 scopus 로고    scopus 로고
    • The cholesteryl ester transfer protein (CETP) Taq1B polymorphism in the Cholesterol and ecurrent Events study (CARE): No interaction with the response to pravastatin therapy and no effects on cardiovascular outcome
    • De Grooth GJ, Zerba KE, Huang SP, et al. The cholesteryl ester transfer protein (CETP) Taq1B polymorphism in the Cholesterol And ecurrent Events study (CARE): no interaction with the response to pravastatin therapy and no effects on cardiovascular outcome. J Am Coll Cardiol 2004; 43:854-857. Subanalysis of the cholesterol and recurrent events trial also investigating the potential clinically relevant pharmacogenetic interaction between the Taq1B variant and pravastatin therapy using the incidence of cardiovascular events as outcome.
    • (2004) J Am Coll Cardiol , vol.43 , pp. 854-857
    • De Grooth, G.J.1    Zerba, K.E.2    Huang, S.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.