Sex difference in the regulation of plasma high density lipoprotein cholesterol by genetic and environmental factors

Human Genetics

Volumn 97, Issue 2, 1996, Pages 156-162

  Kauma, Heikki ^a   Savolainen, Markku J ^a   Heikkilä, Riitta ^a   Rantala, Asko O ^a   Lilja, Mauno ^a   Reunanen, Antti ^b   Kesäniemi, Y Antero ^a  

^a UNIVERSITY OF OULU   (Finland)

^b SOCIAL INSURANCE INSTITUTION   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL;

ADULT; ARTICLE; CHOLESTEROL BLOOD LEVEL; ENVIRONMENTAL FACTOR; FEMALE; GENE DOSAGE; GENETIC SUSCEPTIBILITY; GENOTYPE; HEREDITY; HORMONE SUBSTITUTION; HUMAN; MALE; NORMAL HUMAN; POPULATION RESEARCH; POSTMENOPAUSE; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SEX DIFFERENCE; SMOKING;

ADULT; ALCOHOL DRINKING; CARRIER PROTEINS; CHOLESTEROL; CHOLESTEROL ESTER TRANSFER PROTEINS; CHOLESTEROL, HDL; COHORT STUDIES; FEMALE; GENE DOSAGE; GENOTYPE; GLYCOPROTEINS; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; REGRESSION ANALYSIS; SEX CHARACTERISTICS; SMOKING; TRIGLYCERIDES;

EID: 0030021148     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02265258     Document Type: Article

References (30)

1. Applebaum-Bowden D, McLean P, Steinmetz A, Fontana D, Matthys C, Warnick GR, Cheung M, Albers JJ, Hazzard WR (1989) Lipoprotein, apolipoprotein, and lipolytic enzyme changes following estrogen administration in postmenopausal women. J Lipid Res 30: 1895-1906
2. Brown ML, Inazu A, Hesler CB, Aeellon LB, Mann C, Whitlock ME, Marcel YL, Milne RW, Koizumi J, Mabuchi H, Takeda R, Tall AR (1989) Molecular basis of lipid transfer protein deficiency in a family with increased high-density lipoproteins. Nature 342: 448-451
3. Bu X, Warden CH, Xia Y-R, De Meester C, Puppione DL, Teruya S, Lokensgard B, Daneshmand S, Brown J, Gray RJ, Rotter JI, Lusis AJ (1994) Linkage analysis of the genetic determinants of high density lipoprotein concentrations and composition: evidence for involvement of the apolipoprotein A-II and cholesteryl ester transfer protein loci. Hum Genet 93: 639-648
4. Drayna D, Lawn R (1987) Multiple RFLPs at the human cholesteryl ester transfer protein (CETP) locus. Nucleic Acids Res 15: 4698
5. Drayna D, Jarnagin AS, McLean J, Henzel W, Kohr W, Fielding C, Lawn R (1987) Cloning and sequencing of human cholesteryl ester transfer protein cDNA. Nature 327: 632-634
6. Feinberg AP, Vogelstein B (1983) A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 132: 6-13
7. Freeman DJ, Packard CJ, Shepherd J, Gaffney D (1990) Polymorphisms in the gene coding for cholesteryl ester transfer protein are related to plasma high-density lipoprotein cholesterol and transfer protein activity. Clin Sci 79: 575-581
8. Gordon D, Rifkind BM (1989) High-density lipoprotein - the clinical implications of recent studies. N Engl J Med 321: 1311-1316
9. Hannuksela ML, Marcel YL, Kesäniemi YA, Savolainen MJ (1992) Reduction in the concentration and activity of plasma cholesteryl ester transfer protein by alcohol. J Lipid Res 33: 737-744
10. Hannuksela ML, Liinamaa MJ, Kesäniemi YA, Savolainen MJ (1994) Relation of polymorphisms in the cholesteryl ester transfer protein gene to transfer protein activity and plasma lipoprotein levels in alcohol drinkers. Atherosclerosis 110: 35-44
11. Hartl DL (1988) A primer of population genetics. 2nd edn. Sinauer Associates. Sunderland, Mass., USA, pp 40-47
12. Inazu A, Brown ML, Hesler CB, Agellon LB, Koizumi J, Takata K, Maruhama Y, Mabuchi H, Tall AR (1990) Increased high-density lipoprotein levels caused by a common cholesteryl-ester transfer protein gene mutation. N Engl J Med 323: 1234-1238
13. Inazu A, Quinet EM, Brown ML, Moulin P, Tall AR (1991) Alternative splicing of the mRNA encoding the human cholesteryl ester transfer protein. Biochemistry 31: 2352-2358
14. Kessling A, Ouellette S, Bouffard O, Chamberland A, Bétard C, Selinger E, Xhignesse M, Lussier-Cacan S, Davignon J (1991) Patterns of association between genetic variability in apolipoprotein (Apo) B, Apo AI-CIII-AIV. and cholesterol ester transfer protein gene regions and quantitative variation in lipid and lipoprotein traits: influence of gender and exogenous hormone. Am J Hum Genet 50: 92-106
15. Koizumi J, Mabuchi H, Yoshimura A, Michishita I, Takeda M, Itoh H, Sakai Y, Sakai T, Ueda K, Takeda R (1985) Deficiency of serum cholesteryl ester transfer activity in patients with familial hyperalphalipoproteinemia. Atherosclerosis 58: 175-186
16. Kondo I, Berg K, Drayna D, Lawn R (1989) DNA polymorphism at the locus for human cholesteryl ester transfer protein (CETP) is associated with high density lipoprotein cholesterol and apolipoprotein levels. Clin Genet 35: 49-56
17. Marcel YL, Czarnecka H, McPherson R, Hesler CB, Milen RW, Tall AR (1990) Distribution and concentration of cholesteryl ester transfer protein in plasma of normolipidemic subjects. J Clin Invest 85: 10-17
18. Miller SA, Dykes DD, Polesky HF (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16: 1215
19. Moulin P, Cheung MC, Bruce C, Zhong S, Cocke T, Richardson H, Tall AR (1994) Gender effects on the distribution of the cholesteryl ester transfer protein in apolipoprotein A-I-defined lipoprotein subpopulations. J Lipid Res 35: 793-802
20. Pattnaik NM, Montes A, Hughes LB, Zilversmit DB (1978) Cholesteryl ester exchange protein in human plasma: isolation and characterization. Biochim Biophys Acta 530: 428-138
21. Rothman KJ (1990) No adjustments are needed for multiple comparisons. Epidemiology 1: 43-46
22. Savolainen MJ, Hannuksela M, Seppänen S, Kervinen K, Kesäniemi YA (1990) Increased high-density lipoprotein cholesterol concentration in alcoholics is related to low choksteryl ester transfer protein activity. Eur J Clin Invest 20: 593-599
23. Siervogel RM, Morrison JA, Kelly K, Mellies M, Gartside P, Glueck CJ (1980) Familial hyper-alpha-lipoproteinemia in 26 kindreds. Clin Genet 17: 13-25
24. Silliman K, Tall AR, Kretchmer N, Forte TM (1993) Unusual high-density lipoprotein subclass distribution during late pregnancy. Metabolism 42: 1592-1599
25. Tall AR (1993) Plasma cholesteryl ester transfer protein. J Lipid Res 34: 1255-1274
26. Tenkanen H, Koskinen P, Kontula K, Aalto-Setälä K, Mänttári M, Manninen V, Runeberg S-L, Taskinen M-R, Ehnholm C (1991) Polymorphisms of the gene encoding cholesterol transfer protein and serum lipoprotein levels in subjects with and without coronary heart disease. Hum Genet 87: 574-578
27. Tikkanen MJ, Nikkila EA, Kuusi T, Sipinen S (1982) Effects of oestradiol and levonorgestrel on lipoprotein lipids and postheparin plasma lipase activities in normolipoproteinaemic women. Acta Endocrinol 99: 630-635
28. Ukkola O, Savolainen MJ, Salmela PI, Dickhoff K von, Kesäniemi YA (1993) Apolipoprotein B gene DNA polymorphisms are associated with macro- and microangiopathy in non-insulin-dependent diabetes mellitus. Clin Genet 44: 177-184
29. Yamashita S, Hui DY, Wetterau JR, Sprecher DL, Harmony JAK, Sakai N, Matsuzawa Y, Tarui S (1991) Characterization of plasma lipoproteins in patients heterozygous for human plasma cholesteryl ester transfer protein (CETP) deficiency: plasma CETP regulates high-density lipoprotein concentration and composition. Metabolism 40: 756-763
30. Zuliani G, Hobbs HH (1990) EcoNI polymorphism in the human cholesteryl ester transfer protein (CETP) gene. Nucleic Acids Res 18: 2384