Unique features of the sodC-encoded superoxide dismutase from Mycobacterium tuberculosis, a fully functional copper-containing enzyme lacking zinc in the active site

Journal of Biological Chemistry

Volumn 279, Issue 32, 2004, Pages 33447-33455

  Spagnolo, Laura ^a,f   Töro, Imre ^a   D'Orazio, Melania ^c   O'Neil, Peter ^d   Pedersen, Jens Z ^c   Carugo, Oliviero ^b,e   Rotilio, Giuseppe ^c   Battistoni, Andrea ^c   Djinović Carugo, Kristina ^a  

^a SINCROTRONE TRIESTE   (Italy)

^b Ist Naz per la Fis della Materia   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

^d MEDICAL RESEARCH COUNCIL   (United Kingdom)

^e UNIVERSITY OF PAVIA   (Italy)

^f INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; COPPER; DIMERS; ENZYMES; OPTICAL RESOLVING POWER; PROTEINS; X RAY CRYSTALLOGRAPHY; ZINC;

LIGANDS; MUTATION; MYCOBACTERIUM; TUBERCULOSIS;

BIOCHEMISTRY;

BACTERIAL ENZYME; COPPER; COPPER ZINC SUPEROXIDE DISMUTASE; DIMER; HISTIDINE; RECOMBINANT PROTEIN; SUPEROXIDE DISMUTASE; ZINC;

ARTICLE; BACTERIAL GENE; BACTERIAL SURVIVAL; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME KINETICS; ENZYME STABILITY; ENZYME STRUCTURE; GENE DELETION; GENE MUTATION; GEOMETRY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PH; PRIORITY JOURNAL; REACTION ANALYSIS; SEQUENCE HOMOLOGY; SODC GENE; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; BINDING SITES; CATALYSIS; COPPER; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; ELECTRON SPIN RESONANCE SPECTROSCOPY; ELECTROSTATICS; ESCHERICHIA COLI; HYDROGEN-ION CONCENTRATION; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SUPEROXIDE DISMUTASE; ZINC;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS;

EID: 4043057281     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M404699200     Document Type: Article

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