Associations between HPA axis functioning and level of anxiety in children and adolescents with an anxiety disorder

Depression and Anxiety

Volumn 25, Issue 2, 2008, Pages 131-141

  Kallen, Victor L ^a   Tulen, J H M ^b   Utens, E M W J ^a   Treffers, P D A ^c   De Jong, F H ^b   Ferdinand, R F ^a  

^a SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c Acad Ctr Child and Adol Psychiat   (Netherlands)

Author keywords

Adolescents; Anxiety; anxiety disorder; Children; Cortisol; HPA axis

Indexed keywords

HYDROCORTISONE;

ADOLESCENT; ANXIETY DISORDER; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DISEASE ASSOCIATION; FEMALE; HUMAN; HYPOTHALAMUS HYPOPHYSIS SYSTEM; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SCHOOL CHILD; SEPARATION ANXIETY;

ADOLESCENT; AGE FACTORS; ANXIETY DISORDERS; ANXIETY, SEPARATION; AROUSAL; CHILD; CIRCADIAN RHYTHM; FEMALE; HARM REDUCTION; HUMANS; HYDROCORTISONE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; PHOBIC DISORDERS; PITUITARY-ADRENAL SYSTEM; REFERENCE VALUES; SEX FACTORS;

EID: 40349084433     PISSN: 10914269     EISSN: 15206394     Source Type: Journal    
DOI: 10.1002/da.20287     Document Type: Article

References (66)

1. Anisman HA, Griffiths J, Matheson K, Ravindran AV, Merali Z. 2001. Posttraumatic stress symptoms and salivary cortisol levels. Am J Psychiatry 158:1509-1511.
2. Bartels M, De Geus EJC, Kirschbaum C, Sluyter F, Boomsma DI. 2003. Heritability of daytime cortisol levels in Children. Behav Genet 33:421-433.
3. Bierwolf C, Struve K, Marshall L, Born J, Fehm FL. 1997. Slow wave sleep drives inhibition of pituitary-adrenal secretion in humans. J Neuroendocrinol 9:479-484.
4. Bonne O, Brandes D, Segman R, Piman RK, Yehuda R, Shalev A. 2003. Prospective evaluation of plasma cortisol in recent trauma survivors with posttraumatic stress disorder. Psychiatry Res 119:171-175.
5. Bremner JD, Vythilingam M, Vermetten E, Adil J, Khan S, Nazeer A, et al. 2003. Cortisol response to a cognitive stress challenge in posttraumatic stress disorder (PTSD) related to childhood abuse. Psychoneuroendocrinology 28:733-750.
6. Broderick JE, Arnold D, Kudielka BM, Kirschbaum C. 2004. Salivary cortisol sampling compliance: comparison of patients and healthy volunteers. Psychoneuroendocrinology 29:636-650.
7. Charmandari E, Kino T, Souvatzoglou E, Chrousos GP. 2003. Pediatric stress: hormonal mediators and human development. Hormone Res 59:161-179.
8. Chrousos GP. 1997. Stressors, stress and neuroendocrine integration of the adaptive response. Ann N Y Acad Sci 331-335.
9. Clark LA, Watson D. 1991. Tripartite model of anxiety and depression: psychometric evidence and taxonomic implications. J Abnormal Psychol 100:316-336.
10. Clark LA, Watson D, Mineka S. 1994. Temperament, personality, and the mood and anxiety disorders. J Abnormal Psychol 103:103-116.
11. Coplan JD, Moreau D, Chaput F, Martinez JM, Hoven CW, Mandell DJ, Gorman, JM, Pine DS. 2002. Salivary cortisol concentrations before and after carbon-dioxide inhalations in children. Biol Psychiatry 51:326-333.
12. De Kloet ER. 2003. Hormones, brain and stress. Endocrine Regulat 37:51-68.
13. Essau CA, Conradt J, Petermann F. 2000. Frequency, comorbidity, and psychosocial impairment of anxiety disorders in German adolescents. J Anxiety Disorders 14:263-279.
14. Feder A, Coplan JD, Goetz RR, Mathew SJ, Pine DS, Dahl RE. et al. 2004. Twenty-four-hour cortisol secretion patterns in prepubertal children with anxiety or depressive disorders. Biol Psychiatry 56:198-204.
15. Federenko I, Wüst S, Hellhammer DH, Dechoux R, Kumstra R, Kirschbaum C. 2004. Free cortisol awakening responses are influenced by awakening time. Psychoneuroendocrinology 29:174-184.
16. Ferdinand RF, Van Lang NDJ, Ormel J, Verhulst FC. 2006. No distinctions between different types of anxiety symptoms in pre-adolescents from the general population. J Anxiety Disorders 20:207-221.
17. Francis KT. 1979. Psychological correlates of serum indicators of stress in man: a longitudinal study. Psychosomatic Med 41:617-628.
18. Goenjian AK, Pynoos RS, Steinberg AM, Endres D, Abraham K, Geffher ME, Fairbanks LA. 2003. Hypothalamic-pituitary-adrenal activity among Armenian adolescents with PTSD symptoms. J Traumatic Stress 16:319-323.
19. Gerra G, Zaimovic A, Zambelli U, Timpano M, Reali N, Bernasconi S, Brambilla F. 2000. Neuroendocrine responses to psychological stress in adolescents with anxiety disorder. Neuropsychobiology 42:82-92.
20. Gold PW, Goodwin FK, Chrousos GP. 1988a. Clinical and biochemical manifestations of depression: relationship to the neurobiology of stress (part 1). New Engl J Med 319:348-353.
21. Gold PW, Goodwin FK, Chrousos GP. 1988b. Clinical and biochemical manifestations of depression: relationship to the neurobiology of stress (part 2). New Engl J Med 319:348-353.
22. Granger DA, Weisz JR, Kauneckis D. 1994. Neuroendocrine reactivity, internalizing behavior problems, and control-repated cognitions in clinic-referred children and adolescents. J Abnormal Psychol 103:267-276.
23. Grossi G, Ahs A, Lundbeerg U. 1998. Psychological correlates of salivary cortisol secretion among unemployed men and women. Integrative Physiol Behav Sci 33:249-263.
24. Gunnar MR, Vazquez DM. 2001. Low cortisol and a flattening of expected daytime rhythm: potential indices of risk in human development. Develop Psychopathol 13:515-538.
25. Hageman I, Andersen HS, Jorgensen MB. 2001. Post-traumatic stress disorder: a review of psychobiology and pharmacotherapy. Acta Psychiatr Scandinavica 104:411-422.
26. Heim C, Nemeroff CB. 1999. The impact of early adverse experiences on brain systems involved in the pathophysiology of anxiety and affective disorders. Biol Psychiatry 46:1509-1522.
27. Kirschbaum C, Hellhammer DH. 1994. Salivary cortisol in psychoneuroendocrine research: recent developments and applications. Psychoneuroendocrinology 19:313-333.
28. Kirschbaum C, Pirke KM, Hellhammer DH. 1993. The "Trier Social Stress Test" a tool for investigating psychobiological stress responses in a laboratory setting. Neuropsychobiology 28:76-81.
29. Koot H, Van Widenfelt BM. 2000. Dutch translation of Kovacs' Children's Depression Inventory. Intern rapport, Oestgeest: ACKJP Curium.
30. Kovacs M. 1992. Children's Depression Inventory (CDI); Manual. North Tonawanda, NY: Multi-Health Systems.
31. Kudielka BM, Kirschbaum C. 2003. Awakening cortisol responses are influenced by health status and awakening time but not by menstrual cycle phase. Psychoneuroendocrinology 28:35-47.
32. Kudielka BM, Broderick JE, Kirschbaum C. 2003. Compliance with saliva sampling protocols: electronic monitoring reveals invalid cortisol daytime profiles in noncompliant subjects. Psychosomatic Med 65:313-319.
33. Kunz-Ebrecht SR, Kirschbaum C, Marmot M, Steptoe A. 2004. Differences in cortisol awakening response on work days and weekends in women and men from the Whitehall II cohort. Psychoneuroendocrinology 29:516-528.
34. Levine S. 2000. Influence of psychological variables on the activity of the hypothalamic-pituitary-adrenal axis. Eur J Pharmacol 405:149-160.
35. Luboshitzky R. 2000. Endocrine activity during sleep. J Pediatr Endocrinol Metab 13:13-20.
36. March JS, Parker JDA, Sullivan K, Stallings P, Conners K. 1997. The Multidimensional Anxiety Scale for Children (MASC): Factor Structure, Reliability, and Validity. J Am Acad Child Adolesc Psychiatry 36:554-565.
37. Mason JW, Giller EL, Kosten TR, Ostroff RB, Podd L. 1986. Urinary free cortisol levels in posttraumatic stress disordered patients. J Nervous Mental Disease 174:145-149.
38. McEwen BS. 2001. Plasticity of the hippocampus: adaption to chronic stress and allostatic load. Ann N Y Acad Sci 933:265-277.
39. Ockenfels MC, Porter L, Smyth J, Kirschbaum C, Hellhammer DH, Stone AA. 1995. Effect of chronic stress associated with unemployment on salivary cortisol: overall cortisol levels, diurnal rhythm, and acute stress reactivity. Psychosomatic Med 57:460-467.
40. Parker KJ, Schatzberg AF, Lyons DM. 2003. Neuroendocrine aspects of hypercortisolism in major depression. Hormones Behav 43:60-66.
41. Penza KM, Heim C, Nemeroff CB. 2003. Neurobiological effects of childhood abuse: implications for the pathophysiology of depression and anxiety. Arch Womens Mental Health 6:15-22.
42. Preussner JC, Wolf OT, Hellhammer DH, Burscke-Kirschbaum A, Von Auer K, Jobst S, Kaspers F, Kirschbaum C. 1997. Free cortisol levels after awakening: a riable biological marker for the assessment of adrenocortical activity. Life Sci 61:2539-2549.
43. Preussner JC, Hellhammer DH, Kirschbaum C. 1999. Burnout, perceived stress, and cortisol responses to awakening. Psychosomatic Med 61:197-204.
44. Preussner M, Hellhammer DH, Preussner JC, Lupien SJ. 2003a. Self-reported depressive symptoms and stress levels in healthy young men: associations with cortisol response to awakening. Psychosomatic Med 65:92-99.
45. Preussner JC, Kirschbaum C, Meinlschmid G, Hellhammer DH. 2003b. Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change. Psychoneuroendocrinology 28:916-931.
46. Rosmalen JG, Oldehinkel AJ, Ormel J, De Winter AF, Buitelaar JK, Verhulst FC. 2005. Determinants of salivary cortisol levels in 10-12 year old children; a population-based study of individual differences. Psychoneuroendocrinology 30:483-495.
47. Sapolsky RM, Romero LM, Munck AU. 2000. How do glucocorticoids influence stress response? Integrating permissive, suppressive, stimulatory, and preparative actions. Endocrine Rev 21:55-89.
48. Schulz P, Kirschbaum C, Prüssner J, Hellhammer D. 1998. Increased free cortisol secretion after awakening in chronically stressed individuals due to work overload. Stress Med 14:91-97.
49. Seifritz E, Hemmeter U, Trachsel L, Lauer CJ, Hatzinger M, Emrich HM, Holsboer-Trachsler E. 1995. Effects of flumazenil on recovery sleep and hormonal secretion after sleep deprivation in male controls. Psychopharmacology 120:449-456.
50. Siebelink BM, Treffers PhDA. 2000. Dutch translation of the Anxiety Disorders Schedule for DSM-IV: Child version. Lisse: Swets & Zeitlinger.
51. Sitarenios G, Kovacs M. 1999. Use of the Children's Depression Inventory. In: Maruish ME, editor. The use of psychological testing for treatment planning and outcome. London: LEA. p 267-298.
52. Silverman WK, Saavedra LM, Pina AA. 2001. Test-retest reliability of anxiety symptoms and diagnoses with the Anxiety Disorders Interview Schedule for DSM-IV: Child and Parent versions. J Am Acad Child Adolesc Psychiatry 40:937-944.
53. Spencer RL, Miller AH, Moday H, McEwen BS, Blanchard RJ, Blanchard DC, Skai RR. 1996. Chronic social stress produces reductions in available splencic type II corticosteroid receptor binding and plasma corticosteroid binding globulin levels. Psychoneuroendocrinology 21:95-109.
54. Tiemeier H. 2003. Biological risk factors for late life depression. Eur J Epidemiol 2003:745-750.
55. Van Eck M, Berkhof H, Nicolson N, Sulon J. 1996. The effects of perceived stress, traits, mood states, and stressful daily events on salivary cortisol. Psychosomatic Med 58:447-458.
56. Verduin TL, Kendall PC. 2003 Differential occurrence of comorbidity within childhood anxiety disorders. J Clin Child Adolesc Psychol 32:290-295.
57. Vingerhoets AJJM, Ratliff-Crain J, Jabaaij L, Tilders FJH, Moleman P, Menges LJ. 1996. Self-reported stressors, symptom complaints and psychobiological functioning II: psychoneuroendocrine variables. J Psychosomatic Res 40:191-203.
58. Voderholzer U, Hohagen F, Klein T, Jungnickel J, Kirschbaum C, Berger M, Riemann D. 2004. Impact of sleep depreivation and subsequent recovery sleep on cortisol in unmedicated depressed patients. Am J Psych 161:1404-1410.
59. Wechsler D. 1974. Wechsler intelligence scale for children-revised: manual. New York: Psychological Corporation.
60. Wessa M, Rohleder N, Kirschbaum C, Flor H. 2006. Altered cortisol awakening response in posttraumatic stress disorder. Psychoneuroendocrinology 31:209-215.
61. Wüst S, Federenko I, Hellhammer DH, Kirschbaum C. 2000a. Genetic factors, perceived chronic stress, and free cortisol response to awakening. Psychoneuroendocrinology 25:707-720.
62. Wüst S, Wolf J, Hellhammer DH, Federenko I, Schommer N, Kirschbaum C. 2000b. The cortisol awakening response - normal values and confounds. Noise Health 7:79-88.
63. Yehuda R, Kahana B, Binder-Brynes K, Southwick SM, Mason JW, Giller EL. 1995. Low urinary cortisol excretion in holocaust survivors woth posttraumatic stress disorder. Am J Psychiatry 152:982-986.
64. Yehuda R, Golier JA, Kaufman S. 2005a. Circadian rhythm of salivary cortisol in holocaust survivors with and without PTSD. Am J Psychiatry 162:998-1000.
65. Yehuda R, Yang RK, Buchsbaum MS, Golier JA. 2006. Alterations in cortisol negative feedback inhibition as examined using the ACTH response to cortisol administration in PTSD. Psychoneuroendocrinology. 31:447-451.
66. Zarkovic M, Stefanova E, Ciric J, Penezic Z, Kostic V, Sumarac-Dumanovic M, et al. 2003. Prolonged psychological stress suppresses cortisol secretion. Clin Endocrinol 59:811-816.