Chronic social stress produces reductions in available splenic type II corticosteroid receptor binding and plasma corticosteroid binding globulin levels

Psychoneuroendocrinology

Volumn 21, Issue 1, 1996, Pages 95-109

  Spencer, Robert L ^a   Miller, A H ^b   Moday, H ^c   McEwen, B S ^c   Blanchard, R J ^d   Blanchard, D C ^e   Sakai, R R ^f  

^a UNIVERSITY OF COLORADO   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

^d UNIVERSITY OF HAWAII   (United States)

^e UNIVERSITY OF HAWAII   (United States)

^f UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Corticosteroid binding globulin; Corticosteroid receptors; HPA axis; Rat; Social stress; Spleen

Indexed keywords

EID: 0029944573     PISSN: 03064530     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-4530(95)00020-8     Document Type: Article

References (26)

1. Bateman A, Singh A, Kral T, Solomon S (1989) The immune-hypothalamic-pituitary-adrenal axis. Endocr Rev 10:92-112.
2. Besedovsky HO, Del Rey AE, Sorkin E (1985) Immune-neuroendocrine interactions. J Immunol 135:750s-754s.
3. Blanchard DC, Blanchard RJ (1990) Behavioral correlates of chronic dominance-subordination relationships of male rats in a seminatural situation. Neurosci Biobehav Rev 14:455-462.
4. Blanchard DC, Spencer RL, Weiss SM, Blanchard RJ, McEwen BS, Sakai RR (1995) Visible burrow system as a model of chronic social stress: behavioral and neuroendocrine correlates. Psychoneuroendocrinology, 20:117-134.
5. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 27:248-254.
6. Chou YC, Luttge WG (1988) Activated type II receptors in brain cannot rebind glucocorticoids: relationship to progesterone's antiglucocorticoid actions. Brain Res 440:67-68.
7. Dhabhar FS, Miller AH, McEwen BS, Spencer RL (1995) Differential activation of adrenal steroid receptors in neural and immune tissues of Sprague-Dawley, Fischer 344, and Lewis rats. J Neuroimmunol 56:77-90.
8. Dong Y, Poellinger L, Gustafsson J, Okret S (1988) Regulation of glucocorticoid receptor expression: evidence for transcriptional and posttranslational mechanisms. Mol Endocrinol 2:1256-1264.
9. Hammond GL, Smith CL, Paterson NAM, Sibbald WJ (1990) A role for corticosteroid-binding globulin in delivery of cortisol to activated neutrophils. J Clin Endocrinol Metab 71:34-39.
10. Litwack G (1988) The glucocorticoid receptor at the protein level. Cancer Res 48:2636-2640.
11. McEwen BS, Wallach G, Magnus C (1974) Corticosterone binding to hippocampus: immediate and delayed influences of the absence of adrenal secretion. Brain Res 70:321-334.
12. Miller AH, Spencer RL, Kim C, McEwen BS, Stein M (1991) Adrenal steroid receptor activation in vivo and immune function. Am J Physiol 261:E126-E131.
13. Miller AH, Spencer RL, Stein M, McEwen BS (1990) Adrenal steroid receptor binding in spleen and thymus after stress or dexamethasone. Am J Physiol 259:E405-E412.
14. Perrin FM, Forest MG (1975) Time course of the effect of adrenalectomy on transcortin binding characteristics: appraisal of different methods of calculation. Endocrinology 96:869-878.
15. Reul JMHM, Bosch FR van den, deKloet ER (1987) Relative occupation of type I and type II corticosteroid receptors in rat brain following stress and dexamethasone treatment: functional implications. J Endocrinol 115:459-467.
16. Rosner W (1990) The functions of corticosteroid-binding globulin and sex hormone-binding globulin: recent advances. Endocr Rev 11:80-91.
17. Sapolsky RM, Krey LC, McEwen BS (1984) Stress down-regulates corticosterone receptors in a site-specific manner in the brain. Endocrinology 114:287-292.
18. Sapolsky RM, Krey LC, McEwen BS (1985) Down-regulation of neural corticosterone receptors by corticosterone and dexamethasone. Brain Res 339:161-165.
19. Savu L, Lombart C, Nunez EA (1980) Corticosterone binding globulin: an acute phase "negative" protein in the rat. FEBS Lett 113:102-106.
20. Savu L, Zouaghi H, Carli A, Nunez EA (1981) Serum depletion of corticosteroid binding activities, an early marker of human septic shock. Biochem Biophys Res Commun 102:411-419.
21. Siiteri PK, Murai JT, Hammond GL, Nisker JA, Raymoure WJ, Kuhn RW (1982) The serum transport of steroid hormones. Rec Prog Horm Res 38:457-510.
22. Smith CL, Hammond GL (1992) Hormonal regulation of corticosteroid-binding globulin biosynthesis in the male rat. Endocrinology 130:2245-2251.
23. Spencer RL, Miller AH, Moday H, Stein M, McEwen BS (1993) Diurnal differences in basal and acute stress levels of type I and type II adrenal steroid receptor activation in neural and immune tissues. Endocrinology 133:1941-1950.
24. Spencer RL, Miller AH, Stein M, McEwen BS (1991) Corticosterone regulation of type I and type II adrenal steroid receptors in brain, pituitary, and immune tissue. Brain Res 549:236-246.
25. Spencer RL, Young E, Choo P, McEwen BS (1990) Adrenal steroid type I and type II receptor binding: estimates of in vivo receptor number, occupancy, and activation with varying level of steroid. Brain Res 514:37-48.
26. Westphal U (1971) Steroid-protein Interactions. Springer, New York