Glycosylation changes in hFUT1 transgenic mice increase TCR signaling and apoptosis resulting in thymocyte maturation arrest

Molecular Immunology

Volumn 45, Issue 8, 2008, Pages 2401-2410

  Moore, Gregory T C ^a,b   Brown, Steven J ^a,b   Winterhalter, Adam C ^a   Lust, Mark ^a,b   Salvaris, Evelyn J ^a   Selan, Carly ^a   Nandurkar, Harshal H ^a,b   Desmond, Paul V ^a,b   Cowan, Peter J ^a,b   d'Apice, Anthony J F ^a,b  

^a ST VINCENT S HOSPITAL   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Apoptosis; CD45; Glycosylation; T cell signaling; Thymus

Indexed keywords

ALPHA1 2 FUCOSYLTRANSFERASE; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL COUNT; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GLYCOSYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

ANIMALS; ANNEXIN A5; ANTIGENS, CD45; APOPTOSIS; CELL DIFFERENTIATION; DIMERIZATION; FUCOSYLTRANSFERASES; GLYCOSYLATION; HUMANS; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; N-ACETYLNEURAMINIC ACID; PHOSPHORYLATION; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; ZAP-70 PROTEIN-TYROSINE KINASE;

MUS; MUS MUSCULUS;

EID: 40149092812     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2007.11.006     Document Type: Article

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