Epitope-specific crosslinking of CD45 down-regulates membrane-associated tyrosine phosphatase activity and triggers early signalling events in human activated T cells

Immunology

Volumn 113, Issue 4, 2004, Pages 441-452

  Spertini, François ^a   Perret Menoud, Veronique ^a   Barbier, Nathalie ^a   Chatila, Talal ^b   Barbey, Catherine ^a   Corthesy, Blaise ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b WASHINGTON UNIVERSITY   (United States)

Author keywords

CD45; Cell activation; Protein kinase phosphatase; Signal transduction; T cell

Indexed keywords

CALCIUM ION; CD3 ANTIGEN; CD45 ANTIGEN; LAT PROTEIN; PHOSPHATIDYLINOSITIDE; PROTEIN KINASE ZAP 70; PROTEIN P56; PROTEIN P72; PROTEIN TYROSINE PHOSPHATASE; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; VAV PROTEIN;

ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ANTIGENS, CD45; CELLS, CULTURED; DOWN-REGULATION; EPITOPES, T-LYMPHOCYTE; HUMANS; LYMPHOCYTE ACTIVATION; PHOSPHORYLATION; PROTEIN-TYROSINE-PHOSPHATASE; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 9944246010     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2004.01986.x     Document Type: Article

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