Synthesis and adenosine receptor binding studies of some novel triazolothienopyrimidines

European Journal of Medicinal Chemistry

Volumn 43, Issue 3, 2008, Pages 614-620

  Raghu Prasad, Mailavaram ^a   Raghuram Rao, Akkinepally ^a   Shanthan Rao, Pamulaparthy ^b   Rajan, Kombu Subramanian ^a   Meena, Shanmugam ^a   Madhavi, Kuchana ^a  

^a KAKATIYA UNIVERSITY   (India)

^b INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Adenosine A1 receptor antagonists; Radioligand binding assays; Synthesis; Triazolopyrimidines; Triazolothienopyrimidines

Indexed keywords

4 HYDRAZINO 2 ETHYL 5,6 DIMETHYLTHIENO[2,3 D]PYRIMIDINE; 4 HYDRAZINO 2 ETHYL 5,6,7,8 TETRAHYDRO[1]BENZOTHEINO[2,3 D]PYRIMIDINE; 4 HYDRAZINO 2 PROPYL 5,6 DIMETHYLTHIENO[2,3 D]PYRIMIDINE; 4 HYDRAZINO 2 PROPYL 5,6,7,8 TETRAHYDRO[1]BENZOTHIENO[2,3 D]PYRIMIDINE; 5 BENZYL 8,9 DIMETHYLTHIENO[3,2 E][1,2,4]TRIAZOLO[4,3 C]PYRIMIDINE 3(2H) THIONE; 5 BENZYL 8,9,10,11 TETRAHYDRO[1]BENZOTHIENO[3,2 E][1,2,4]TRIAZOLO[4,3 C]PYRIMIDINE 3(2H) THIONE; 5 ETHYL 8,9 DIMETHYLTHIENO[3,2 E][1,2,4]TRIAZOLO[4,3 C]PYRIMIDINE 3(2H) THIONE; 5 ETHYL 8,9,10,11 TETRAHYDRO[1]BENZOTHIENO[3,2 E][1,2,4]TRIAZOLO[4,3 C]PYRIMIDINE 3(2H) THIONE; 5 METHYL 8,9 DIMETHYLTHIENO[3,2 E][1,2,4]TRIAZOLO[4,3 C]PYRIMIDINE 3(2H) THIONE; 5 METHYL 8,9,10,11 TETRAHYDRO[1]BENZOTHIENO[3,2 E][1,2,4]TRIAZOLO[4,3 C]PYRIMIDINE 3(2H) THIONE; 5 PHENYL 8,9 DIMETHYLTHIENO[3,2 E][1,2,4]TRIAZOLO[4,3 C]PYRIMIDINE 3(2H) THIONE; 5 PHENYL 8,9,10,11 TETRAHYDRO[1]BENZOTHIENO[3,2 E][1,2,4]TRIAZOLO[4,3 C]PYRIMIDINE 3(2H) THIONE; 5 PROPYL 8,9 DIMETHYLTHIENO[3,2 E][1,2,4]TRIAZOLO[4,3 C]PYRIMIDINE 3(2H) THIONE; 5 PROPYL 8,9,10,11 TETRAHYDRO[1]BENZOTHIENO[3,2 E][1,2,4]TRIAZOLO[4,3 C]PYRIMIDINE 3(2H) THIONE; 5 PYRIDYL 8,9,10,11 TETRAHYDRO[1]BENZOTHIENO[3,2 E][1,2,4]TRIAZOLO[4,3 C]PYRIMIDINE 3(2H) THIONE; ADENOSINE A1 RECEPTOR ANTAGONIST; ADENOSINE RECEPTOR; CARBON DISULFIDE; CP 68247; HYDRAZINE; THIENOPYRIDINE DERIVATIVE; TRIAZOLOTHIENOPYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CYCLIZATION; DRUG BINDING; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; NONHUMAN; PHARMACOPHORE; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; STRUCTURE ACTIVITY RELATION;

EID: 40049087249     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.05.001     Document Type: Article

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