3-Aryl[1,2,4]triazino[4,3-α]benzimidazol-4(10H)-ones: A new class of selective A1 adenosine receptor antagonists

Journal of Medicinal Chemistry

Volumn 44, Issue 3, 2001, Pages 316-327

  Da Settimo, F ^a   Primofiore, G ^a   Taliani, S ^a   Marini, A M ^a   La Motta, C ^a   Novellino, E ^b   Greco, G ^b   Lavecchia, A ^b   Trincavelli, L ^a   Martini, C ^a  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

10 METHYL 3 PHENYL[1,2,4]TRIAZINO[4,3 A]BENZIMIDAZOL 4(10H) ONE DERIVATIVE; ADENOSINE A1 RECEPTOR ANTAGONIST; ADENOSINE A2A RECEPTOR; ADENOSINE A3 RECEPTOR; BENZENE DERIVATIVE; BENZIMIDAZOLE DERIVATIVE; BENZODIAZEPINE RECEPTOR; NITROGEN; UNCLASSIFIED DRUG;

ALKYLATION; ANIMAL CELL; ARTICLE; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HYDROGEN BOND; IN VITRO STUDY; LIGAND BINDING; NONHUMAN; PHARMACOPHORE;

AMINO ACID SEQUENCE; ANIMALS; BENZIMIDAZOLES; BRAIN; CATTLE; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; RADIOLIGAND ASSAY; RECEPTORS, PURINERGIC P1;

EID: 0035253846     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm001054m     Document Type: Article

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