XH-14 analogues as adenosine antagonists

Bioorganic and Medicinal Chemistry

Volumn 6, Issue 9, 1998, Pages 1517-1524

  Scammells, Peter J ^a   Baker, Stephen P ^b   Beauglehole, Anthony R ^a  

^a DEAKIN UNIVERSITY   (Australia)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

A1 adenosine receptor; Adenosine antagonist; Benzofuran

Indexed keywords

2 (4 HYDROXY 3 METHOXYPHENYL) 5 (3 HYDROXYPROPYL) 7 METHOXY 3 BENZO[B]FURANCARBALDEHYDE; 5 (3' HYDROXYPROPYL) 7 METHOXY 2 (3' METHOXY 4' HYDROXYPHENYL)BENZO[B]FURAN 3 CARBALDEHYDE DERIVATIVE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

ADENOSINE; BENZOFURANS; CELL LINE; MAGNETIC RESONANCE SPECTROSCOPY; RECEPTORS, PURINERGIC P1; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032169116     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(98)00093-5     Document Type: Article

References (14)

1. Daly, J. W. J. Med. Chem. 1982, 25, 197.
2. Jacobson, K. A.; van Galen, P. J. M.; Williams, M. J. Med. Chem. 1992, 35, 407.
3. Williams, M. Drug News & Perspectives, 1991, 4, 5.
4. Collis, M. J.; Hourani, S. M. O. TIPS Reviews, 1993, 14, 360.
5. Yang, Z.; Hon, P. M.; Chui, K. Y.; Xu, Z. L.; Chang, H. M.; Lee, C. M.; Cui, Y. X.; Wong, H. N. C.; Poon, C. D.; Fung, B. M. Tetrahedron 1991, 32, 2061.
6. Yang, Z.; Liu, H. B.; Lee, C. M.; Chang, H. M.; Wong, H. N. C. J. Org. Chem. 1992, 57, 7428.
7. Jacobson, K. A.; Kiriasis, L.; Barone, S.; Bradbury, B. J.; Kammula, U.; Campagne, J. M.; Secunda, S.; Daly, J. W.; Neumeyer, J. L.; Pfleiderer, W. J. Med. Chem. 1989, 32, 1873.
8. Baillargeon, V. P.; Stille, J. K. J. Am. Chem. Soc. 1986, 108, 452.
9. Okano, T.; Harada, N.; Kiji, J. Bull. Chem. Soc. Jpn. 1994, 67, 2329.
10. Scammells, P. J.; Tiekink, E. Z. Krist. 1998, 213, 59.
11. Larock, R. C.; Yum, E.; Doty, M. J.; Sham, K. K. C. J. Org. Chem. 1995, 60, 3270.
12. Hutchinson, S. A.; Luetjens, H.; Scammells, P. J. Bioorg. Med. Chem. Lett. 1997, 7, 3081.
13. Scammells, P. J.; Baker, S. P.; Berlardinelli, L.; Olsson, R. A. J. Med. Chem. 1994, 37, 2704.
14. Cheng, Y.; Prusoff, S. Biochem. Pharmacol. 1973, 22, 3099.