ZNF418, a novel human KRAB/C2H2 zinc finger protein, suppresses MAPK signaling pathway

Molecular and Cellular Biochemistry

Volumn 310, Issue 1-2, 2008, Pages 141-151

  Li, Yongqing ^a   Yang, Dan ^a   Bai, Yan ^a   Mo, Xiaoyang ^a   Huang, Wen ^a   Yuan, Wuzhou ^a   Yin, Zhaochu ^a   Deng, Yun ^a   Murashko, Oleg ^a   Wang, Yuequn ^a   Fan, Xiongwei ^a   Zhu, Chuanbing ^a   Ocorr, Karen ^a   Bodmer, Rolf ^a   Wu, Xiushan ^a  

^a HUNAN NORMAL UNIVERSITY   (China)

Author keywords

C2H2 zinc finger protein; KRAB box; MAPK signaling pathway; ZNF418

Indexed keywords

MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN ZNF418; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ADULT; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL STRAIN COS7; CHROMOSOME 19Q; CONTROLLED STUDY; DNA LIBRARY; EMBRYO; EMBRYO DEVELOPMENT; EXON; FETUS; GENE EXPRESSION; GENE IDENTIFICATION; GENE OVEREXPRESSION; GENE SILENCING; HEART DEVELOPMENT; HUMAN; HUMAN TISSUE; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PROTEIN DOMAIN; PROTEIN FAMILY; REPORTER GENE; RNA TRANSCRIPTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ZINC FINGER MOTIF;

EID: 39949084887     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-007-9674-4     Document Type: Article

References (38)

1. 1. E Maldonado M Hampsey D Reinberg 1999 Repression targeting the heart of the matter Cell 99 455 458 10589673 10.1016/S0092-8674(00)81533-0 1:CAS:528:DyaK1MXnvVSis7g%3D Maldonado E, Hampsey M, Reinberg D (1999) Repression targeting the heart of the matter. Cell 99:455–458
2. 2. L Zawel D Reinberg 1995 Common themes in assembly and function of eukaryotic transcription complexes Annu Rev Biochem 64 533 561 7574492 10.1146/annurev.bi.64.070195.002533 1:CAS:528:DyaK2MXmsl2qtr4%3D Zawel L, Reinberg D (1995) Common themes in assembly and function of eukaryotic transcription complexes. Annu Rev Biochem 64:533–561
3. 3. A Klug JWR Schwabe 1995 Protein motifs 5. Zinc fingers FASEB J 9 597 604 7768350 1:CAS:528:DyaK2MXmt1ajtr4%3D Klug A, Schwabe JWR (1995) Protein motifs 5. Zinc fingers. FASEB J 9:597–604
4. 4. EJ Bellefroid PJ Lecocq A Benhida DA Poncelet A Belavew JA Martial 1989 The human genome contains hundreds of genes coding for finger proteins of the Krüppel type DNA 8 377 387 2505992 1:CAS:528:DyaK3cXhslehu7c%3D Bellefroid EJ, Lecocq PJ, Benhida A, Poncelet DA, Belavew A, Martial JA (1989) The human genome contains hundreds of genes coding for finger proteins of the Krüppel type. DNA 8:377–387
5. 5. ES Lander LM Linton B Birren C Nusbaum MC Zody J Baldwin K Devon K Dewar M Doyle 2001 Initial sequencing and analysis of the human genome Nature 409 860 921 11237011 10.1038/35057062 1:CAS:528:DC%2BD3MXhsFCjtLc%3D Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, Devon K, Dewar K, Doyle M et al (2001) Initial sequencing and analysis of the human genome. Nature 409:860–921
6. 6. DT Dang J Pevsner VW Yang 2000 The biology of the mammalian Kruppel-like family of transcription factors Int J Biochem Cell Biol 32 1103 1121 11137451 10.1016/S1357-2725(00)00059-5 1:CAS:528:DC%2BD3MXns12rsA%3D%3D Dang DT, Pevsner J, Yang VW (2000) The biology of the mammalian Kruppel-like family of transcription factors. Int J Biochem Cell Biol 32:1103–1121
7. 7. RT Nolte RM Conlin SC Harrison RS Brown 1998 Differing roles for zinc finger in DNA recognition: structure of a six-finger transcription factor IIIA complex Proc Natl Acad Sci USA 95 2938 2943 9501194 10.1073/pnas.95.6.2938 1:CAS:528:DyaK1cXitV2is7Y%3D Nolte RT, Conlin RM, Harrison SC, Brown RS (1998) Differing roles for zinc finger in DNA recognition: structure of a six-finger transcription factor IIIA complex. Proc Natl Acad Sci USA 95:2938–2943
8. 8. N Makoto N Wataru S Yasuhisa S Yukio 2001 Significant effect of linker sequence on DNA recognition by multi-zinc finger protein Biochem Biophys Res Commun 282 1001 1007 10.1006/bbrc.2001.4672 Makoto N, Wataru N, Yasuhisa S, Yukio S (2001) Significant effect of linker sequence on DNA recognition by multi-zinc finger protein. Biochem Biophys Res Commun 282:1001–1007
9. 9. SW Rue BW Kim DY Jun YH Kim 2001 Nucleotide sequence and cell cycle-associated differential expression of ZF5128, a novel Kruppel type zinc finger protein gene Biochim Biophys Acta 1522 230 237 11779640 1:CAS:528:DC%2BD38Xls1ehuw%3D%3D Rue SW, Kim BW, Jun DY, Kim YH (2001) Nucleotide sequence and cell cycle-associated differential expression of ZF5128, a novel Kruppel type zinc finger protein gene. Biochim Biophys Acta 1522:230–237
10. 10. EJ Bellefroid DA Poncelet PJ Lecocq O Revelant JA Martial 1991 The evolutionarily conserved Kruppel-associated box domain defines a subfamily of eukaryotic multifingered proteins Proc Natl Acad Sci USA 88 3608 3612 2023909 10.1073/pnas.88.9.3608 1:CAS:528:DyaK38Xhslegtw%3D%3D Bellefroid EJ, Poncelet DA, Lecocq PJ, Revelant O, Martial JA (1991) The evolutionarily conserved Kruppel-associated box domain defines a subfamily of eukaryotic multifingered proteins. Proc Natl Acad Sci USA 88:3608–3612
11. 11. L Medugno P Costanzo A Lupo M Monti 2003 A novel zinc finger transcriptional repressor, ZNF224, interacts with the negative regulatory element (AldA-NRE) and inhibits gen expression FEBS Lett 532 93 100 10.1016/S0014-5793(02)03783-3 Medugno L, Costanzo P, Lupo A, Monti M et al (2003) A novel zinc finger transcriptional repressor, ZNF224, interacts with the negative regulatory element (AldA-NRE) and inhibits gen expression. FEBS Lett 532:93–100
12. 12. J Yang 2003 A novel zinc finger protein, ZZaPK, interacts with ZAK and stimulates the ZAK-expressing cells re-entering the cell cycle Biochem Biophys Res Commun 301 71 77 12535642 10.1016/S0006-291X(02)02980-7 1:CAS:528:DC%2BD3sXjtFemuw%3D%3D Yang J (2003) A novel zinc finger protein, ZZaPK, interacts with ZAK and stimulates the ZAK-expressing cells re-entering the cell cycle. Biochem Biophys Res Commun 301:71–77
13. 13. A Lupo P Costanzo L Medugno I Romeo F Salvatore P Izzo 1997 Negative regulation of the mouse aldolase A gene. A cell cycle-dependent DNA binding activity functions as a silencer of gene transcription J Biol Chem 272 31641 31647 9395505 10.1074/jbc.272.50.31641 1:CAS:528:DyaK2sXotVSktbs%3D Lupo A, Costanzo P, Medugno L, Romeo I, Salvatore F, Izzo P (1997) Negative regulation of the mouse aldolase A gene. A cell cycle-dependent DNA binding activity functions as a silencer of gene transcription. J Biol Chem 272:31641–31647
14. 14. EJ Bellefroid JC Marine T Ried PJ Leeocq M Riviere C Amemiya DA Poncelet PG Coulie P Jong de C Szpirer DC Ward JA Martial 1993 Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells EMBO J 12 1363 1374 8467795 1:CAS:528:DyaK3sXisV2jtr0%3D Bellefroid EJ, Marine JC, Ried T, Leeocq PJ, Riviere M, Amemiya C, Poncelet DA, Coulie PG, de Jong P, Szpirer C, Ward DC, Martial JA (1993) Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. EMBO J 12:1363–1374
15. 15. R Lovering J Trowsdale 1991 A gene encoding 22 highly related zinc fingers is expressed in lymphoid cell lines Nucleic Acids Res 19 2921 2928 1711675 10.1093/nar/19.11.2921 1:CAS:528:DyaK38Xht1agsrg%3D Lovering R, Trowsdale J (1991) A gene encoding 22 highly related zinc fingers is expressed in lymphoid cell lines. Nucleic Acids Res 19:2921–2928
16. 16. N Tommerup L Aagaard CL Lund E Boel S Baxendale GP Bates H Lehrach H Vissing 1993 A zinc-finger gene ZNF141 mapping at 4p16.3/D4S90 is a candidate gene for the Wolf-Hirschhorn (4p-) syndrome Hum Mol Genet 2 1571 1575 8268908 10.1093/hmg/2.10.1571 1:CAS:528:DyaK2cXpslCqtA%3D%3D Tommerup N, Aagaard L, Lund CL, Boel E, Baxendale S, Bates GP, Lehrach H, Vissing H (1993) A zinc-finger gene ZNF141 mapping at 4p16.3/D4S90 is a candidate gene for the Wolf-Hirschhorn (4p-) syndrome. Hum Mol Genet 2:1571–1575
17. 17. Y Wang K Luo Y Li C Zhu X Wu 2001 A rapid method of extracting total RNA from embryo tissues Life Sci Res 5 1 88 90 1:CAS:528:DC%2BD3MXjt1ygu70%3D Wang Y, Luo K, Li Y, Zhu C, Wu X (2001) A rapid method of extracting total RNA from embryo tissues. Life Sci Res 5(1):88–90
18. 18. C Huang Y Wang D Li Y Li J Luo W Yuan Y Ou C Zhu Y Zhang Z Wang M Liu X Wu 2004 Inhibition of transcriptional activities of AP-1 and c-Jun by a new zinc finger protein ZNF394 Biochem Biophys Res Commun 320 4 1298 305 15249231 10.1016/j.bbrc.2004.06.080 1:CAS:528:DC%2BD2cXls1eisbw%3D Huang C, Wang Y, Li D, Li Y, Luo J, Yuan W, Ou Y, Zhu C, Zhang Y, Wang Z, Liu M, Wu X (2004) Inhibition of transcriptional activities of AP-1 and c-Jun by a new zinc finger protein ZNF394. Biochem Biophys Res Commun 320(4):1298–305
19. 19. Y Wang Y Li X Qi W Yuan J Ai C Zhu L Cao H Yang F Liu X Wu M Liu 2004 TRIM45, a novel human RBCC/TRIM protein, inhibits transcriptional activities of ElK-1 and AP-1 Biochem Biophy Res Commun 323 9 16 10.1016/j.bbrc.2004.08.048 1:CAS:528:DC%2BD2cXntlOisLo%3D Wang Y, Li Y, Qi X, Yuan W, Ai J, Zhu C, Cao L, Yang H, Liu F, Wu X, Liu M (2004) TRIM45, a novel human RBCC/TRIM protein, inhibits transcriptional activities of ElK-1 and AP-1. Biochem Biophy Res Commun 323:9–16
20. 20. F Yi Y Li W Ma D Li C Zhu J Luo Y Wang X Huang W Yuan M Liu X Wu 2004 A novel KRAB zinc-finger protein, ZNF480, expresses in human heart and activates transcriptional activities of AP-1 and SRE Biochem Biophys Res Commun 320 409 415 15219843 10.1016/j.bbrc.2004.05.182 1:CAS:528:DC%2BD2cXlt1egtrs%3D Yi F, Li Y, Ma W, Li D, Zhu C, Luo J, Wang Y, Huang X, Yuan W, Liu M, Wu X (2004) A novel KRAB zinc-finger protein, ZNF480, expresses in human heart and activates transcriptional activities of AP-1 and SRE. Biochem Biophys Res Commun 320:409–415
21. 21. G Brawerman 1990 Mechanisms of mRNA decay Trends Biotechnol 8 171 174 1366620 10.1016/0167-7799(90)90167-V 1:CAS:528:DyaK3cXltFSqur4%3D Brawerman G (1990) Mechanisms of mRNA decay. Trends Biotechnol 8:171–174
22. 22. C Looman M Abrink C Mark L Hellman 2002 KRAB zinc finger proteins: an analysis of the molecular mechanisms governing their increase in numbers and complexity during evolution Mol Biol Evol 19 2118 2130 12446804 1:CAS:528:DC%2BD38Xps12hs7w%3D Looman C, Abrink M, Mark C, Hellman L (2002) KRAB zinc finger proteins: an analysis of the molecular mechanisms governing their increase in numbers and complexity during evolution. Mol Biol Evol 19:2118–2130
23. 23. SS Kim YM Chen E O’Leary R Witzgall M Vidal JV Bonventre 1996 A novel member of the RING finger family, KRIP-1, associates with the KRAB-A transcriptional repressor domain of zinc finger proteins Proc Natl Acad Sci USA 93 15299 15304 8986806 10.1073/pnas.93.26.15299 1:CAS:528:DyaK2sXnt1eg Kim SS, Chen YM, O’Leary E, Witzgall R, Vidal M, Bonventre JV (1996) A novel member of the RING finger family, KRIP-1, associates with the KRAB-A transcriptional repressor domain of zinc finger proteins. Proc Natl Acad Sci USA 93:15299–15304
24. 24. H Peng GE Begg DC Schultz JR Friedman DE Jensen DW Speicher FJ Rauscher 2000 Reconstitution of the KRAB-KAP-1 repressor complex: a model system for defining the molecular anatomy of RING-B box-coiled-coil domain-mediated protein–protein interactions J Mol Biol 295 1139 1162 10653693 10.1006/jmbi.1999.3402 1:CAS:528:DC%2BD3cXnsFCitA%3D%3D Peng H, Begg GE, Schultz DC, Friedman JR, Jensen DE, Speicher DW, Rauscher FJ (2000) Reconstitution of the KRAB-KAP-1 repressor complex: a model system for defining the molecular anatomy of RING-B box-coiled-coil domain-mediated protein–protein interactions. J Mol Biol 295:1139–1162
25. 25. H Vissing WK Meyer L Aagaard N Tommerup HJ Thiesen 1995 Repression of transcriptional activity by heterologous KRAB domains present in zinc finger proteins FEBS Lett 369 153 157 7649249 10.1016/0014-5793(95)00728-R 1:CAS:528:DyaK2MXnslyiu7s%3D Vissing H, Meyer WK, Aagaard L, Tommerup N, Thiesen HJ (1995) Repression of transcriptional activity by heterologous KRAB domains present in zinc finger proteins. FEBS Lett 369:153–157
26. 26. AL Nielsen JA Ortiz J You M Oulad-Abdelghani R Khechumian A Gansmuller P Chambon R Losson 1999 Interaction with members of heterchromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family EMBO J 18 6385 6395 10562550 10.1093/emboj/18.22.6385 1:CAS:528:DyaK1MXns1Ortr0%3D Nielsen AL, Ortiz JA, You J, Oulad-Abdelghani M, Khechumian R, Gansmuller A, Chambon P, Losson R (1999) Interaction with members of heterchromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family. EMBO J 18:6385–6395
27. 27. SX Skapek D Jansen TF Wei T Mcdermott W Huang EN Olson EYHP Lee 2000 Cloning and characterization of a novel Krüppel assosicated box family transcriptional repressor that interacts with the retinoblastoma gene product. RB J Biol Chem 275 7212 7223 10702291 10.1074/jbc.275.10.7212 1:CAS:528:DC%2BD3cXhvVGku7g%3D Skapek SX, Jansen D, Wei TF, Mcdermott T, Huang W, Olson EN, Lee EYHP (2000) Cloning and characterization of a novel Krüppel assosicated box family transcriptional repressor that interacts with the retinoblastoma gene product. RB. J Biol Chem 275:7212–7223
28. 28. SM Hollenberg R Sternglanz PF Cheng H Weintraub 1995 Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system Mol Cell Biol 15 3813 3822 7791788 1:CAS:528:DyaK2MXmsVClsLY%3D Hollenberg SM, Sternglanz R, Cheng PF, Weintraub H (1995) Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system. Mol Cell Biol 15:3813–3822
29. 29. RJ Davis 1994 MAPK: new Juk expands the group Trends Biochem Sci 19 470 473 7855889 10.1016/0968-0004(94)90132-5 1:CAS:528:DyaK2MXitlyhs70%3D Davis RJ (1994) MAPK: new Juk expands the group. Trends Biochem Sci 19:470–473
30. 30. L Chang M Karin 2001 Mammalian MAP kinase signaling cascades Nature 410 37 40 11242034 10.1038/35065000 1:CAS:528:DC%2BD3MXhvVSgs7k%3D Chang L, Karin M (2001) Mammalian MAP kinase signaling cascades. Nature 410:37–40
31. 31. J English G Pearson J Wilsbacher J Swantek M Karandikar S Xu MH Cobb 1999 New insights into the control of MAP kinase pathways Exp Cell Res 253 255 270 10579927 10.1006/excr.1999.4687 1:CAS:528:DyaK1MXnsF2it70%3D English J, Pearson G, Wilsbacher J, Swantek J, Karandikar M, Xu S, Cobb MH (1999) New insights into the control of MAP kinase pathways. Exp Cell Res 253:255–270
32. 32. RJ Davis 1993 The mitogen-activated protein kinase signal transduction pathway J Biol Chem 268 14553 14556 8325833 1:CAS:528:DyaK3sXltFWnsL4%3D Davis RJ (1993) The mitogen-activated protein kinase signal transduction pathway. J Biol Chem 268:14553–14556
33. 33. I Sanchez RT Hughes BJ Mayer K Yee JR Woodgett J Avruch JM Kyriakis LI Zon 1994 Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun Nature 372 794 798 7997269 1:CAS:528:DyaK2MXivVSjsrY%3D Sanchez I, Hughes RT, Mayer BJ, Yee K, Woodgett JR, Avruch J, Kyriakis JM, Zon LI (1994) Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Nature 372:794–798
34. 34. S Gupta D Campbell B Derijard RJ Davis 1995 Transcription factor ATF2 regulation by the JNK signal transduction pathway Science 267 389 393 7824938 10.1126/science.7824938 1:CAS:528:DyaK2MXjt12nsbk%3D Gupta S, Campbell D, Derijard B, Davis RJ (1995) Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science 267:389–393
35. 35. G Mavrothalassitis J Ghysdael 2000 Proteins of the ETS family with transcriptional repressor activity Oncogene 19 6524 6532 11175368 10.1038/sj.onc.1204045 1:CAS:528:DC%2BD3MXptVelsA%3D%3D Mavrothalassitis G, Ghysdael J (2000) Proteins of the ETS family with transcriptional repressor activity. Oncogene 19:6524–6532
36. 36. F Jeanmougin JD Thompson M Gouty DG Higgins TJ Gibson 1998 Multiple sequence alignment with Clustal X. Trends Biochem Sci 23 403 405 9810230 10.1016/S0968-0004(98)01285-7 1:CAS:528:DyaK1cXntlansLg%3D Jeanmougin F, Thompson JD, Gouty M, Higgins DG, Gibson TJ (1998) Multiple sequence alignment with Clustal X. Trends Biochem Sci 23:403–405
37. 37. JM Kyriakis J Avruch 2001 Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation Physiol Rev 81 807 869 11274345 1:CAS:528:DC%2BD3MXislCrsb8%3D Kyriakis JM, Avruch J (2001) Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 81:807–869
38. 38. AB Keeton KD Bortoff WL Bennett JL Franklin DY Venable JL Messina 2003 Insulin-regulated expression of Egr-1 and Krox20:dependence on ERK1/2 and interaction with P38 and PI3-kinase pathways Endocrinology 144 5402 5410 12970165 10.1210/en.2003-0592 1:CAS:528:DC%2BD3sXpsV2gurk%3D Keeton AB, Bortoff KD, Bennett WL, Franklin JL, Venable DY, Messina JL (2003) Insulin-regulated expression of Egr-1 and Krox20:dependence on ERK1/2 and interaction with P38 and PI3-kinase pathways. Endocrinology 144:5402–5410